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Neuronal Calcium Sensor 1 is up-regulated in response to stress to promote cell survival and motility in cancer cells.

Grosshans HK, Fischer TT, Steinle JA, Brill AL, Ehrlich BE.

Mol Oncol. 2020 Apr 2. doi: 10.1002/1878-0261.12678. [Epub ahead of print]


Integrin α9β1: a new target to fight thrombosis.

Brill A.

Blood. 2020 Mar 12;135(11):787-788. doi: 10.1182/blood.2020004999. No abstract available.


Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis.

Perry RJ, Zhang D, Guerra MT, Brill AL, Goedeke L, Nasiri AR, Rabin-Court A, Wang Y, Peng L, Dufour S, Zhang Y, Zhang XM, Butrico GM, Toussaint K, Nozaki Y, Cline GW, Petersen KF, Nathanson MH, Ehrlich BE, Shulman GI.

Nature. 2020 Mar;579(7798):279-283. doi: 10.1038/s41586-020-2074-6. Epub 2020 Mar 4.


The dual role of platelet-innate immune cell interactions in thrombo-inflammation.

Rayes J, Bourne JH, Brill A, Watson SP.

Res Pract Thromb Haemost. 2019 Oct 17;4(1):23-35. doi: 10.1002/rth2.12266. eCollection 2020 Jan. Review.


Low dose Btk inhibitors selectively block platelet activation by CLEC-2.

Nicolson PLR, Nock SH, Hinds J, Garcia-Quintanilla L, Smith CW, Campos J, Brill A, Pike JA, Khan AO, Poulter NS, Kavanagh DM, Watson S, Watson CN, Clifford H, Huissoon AP, Pollitt AY, Eble JA, Pratt G, Watson SP, Hughes CE.

Haematologica. 2020 Jan 16. pii: haematol.2019.218545. doi: 10.3324/haematol.2019.218545. [Epub ahead of print]


Polycystin 2 is increased in disease to protect against stress-induced cell death.

Brill AL, Fischer TT, Walters JM, Marlier A, Sewanan LR, Wilson PC, Johnson EK, Moeckel G, Cantley LG, Campbell SG, Nerbonne JM, Chung HJ, Robert ME, Ehrlich BE.

Sci Rep. 2020 Jan 15;10(1):386. doi: 10.1038/s41598-019-57286-x.


Polycystin 2: A calcium channel, channel partner, and regulator of calcium homeostasis in ADPKD.

Brill AL, Ehrlich BE.

Cell Signal. 2020 Feb;66:109490. doi: 10.1016/j.cellsig.2019.109490. Epub 2019 Dec 2.


By word of mouse: using animal models in venous thrombosis research.

Campos J, Brill A.

Platelets. 2019 Oct 18:1-8. doi: 10.1080/09537104.2019.1678117. [Epub ahead of print]


Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation.

Chimen M, Evryviadou A, Box CL, Harrison MJ, Hazeldine J, Dib LH, Kuravi SJ, Payne H, Price JMJ, Kavanagh D, Iqbal AJ, Lax S, Kalia N, Brill A, Thomas SG, Belli A, Crombie N, Adams RA, Evans SA, Deckmyn H, Lord JM, Harrison P, Watson SP, Nash GB, Rainger GE.

Haematologica. 2019 Aug 29. pii: haematol.2018.215145. doi: 10.3324/haematol.2018.215145. [Epub ahead of print]


Intussusception In Adults.

Brill A, Waheed A.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-.
2019 Aug 8.


An Unusual Presentation of Postpartum Spontaneous Coronary Artery Dissection.

Alterie J, Villanueva F, Arekat M, Brill A.

Clin Pract Cases Emerg Med. 2019 May 20;3(3):229-232. doi: 10.5811/cpcem.2019.4.41305. eCollection 2019 Aug.


Association of Radioactive Iodine Treatment With Cancer Mortality in Patients With Hyperthyroidism.

Kitahara CM, Berrington de Gonzalez A, Bouville A, Brill AB, Doody MM, Melo DR, Simon SL, Sosa JA, Tulchinsky M, Villoing D, Preston DL.

JAMA Intern Med. 2019 Jul 1. doi: 10.1001/jamainternmed.2019.0981. [Epub ahead of print] Erratum in: JAMA Intern Med. 2019 Aug 1;179(8):1152.


Polycystin 2 regulates mitochondrial Ca2+ signaling, bioenergetics, and dynamics through mitofusin 2.

Kuo IY, Brill AL, Lemos FO, Jiang JY, Falcone JL, Kimmerling EP, Cai Y, Dong K, Kaplan DL, Wallace DP, Hofer AM, Ehrlich BE.

Sci Signal. 2019 May 7;12(580). pii: eaat7397. doi: 10.1126/scisignal.aat7397.


Estimation of Radiation Doses to U.S. Military Test Participants from Nuclear Testing: A Comparison of Historical Film-Badge Measurements, Dose Reconstruction and Retrospective Biodosimetry.

Simon SL, Bailey SM, Beck HL, Boice JD, Bouville A, Brill AB, Cornforth MN, Inskip PD, McKenna MJ, Mumma MT, Salazar SI, Ukwuani A.

Radiat Res. 2019 Apr;191(4):297-310. doi: 10.1667/RR15247.1. Epub 2019 Feb 21.


Podoplanin regulates the migration of mesenchymal stromal cells and their interaction with platelets.

Ward LSC, Sheriff L, Marshall JL, Manning JE, Brill A, Nash GB, McGettrick HM.

J Cell Sci. 2019 Feb 25;132(5). pii: jcs222067. doi: 10.1242/jcs.222067.


Platelet glycoprotein VI and C-type lectin-like receptor 2 deficiency accelerates wound healing by impairing vascular integrity in mice.

Wichaiyo S, Lax S, Montague SJ, Li Z, Grygielska B, Pike JA, Haining EJ, Brill A, Watson SP, Rayes J.

Haematologica. 2019 Aug;104(8):1648-1660. doi: 10.3324/haematol.2018.208363. Epub 2019 Feb 7.


Sleep-disordered breathing and stroke: chicken or egg?

Alexiev F, Brill AK, Ott SR, Duss S, Schmidt M, Bassetti CL.

J Thorac Dis. 2018 Dec;10(Suppl 34):S4244-S4252. doi: 10.21037/jtd.2018.12.66. Review.


Prevalence of sleep-disordered breathing after stroke and TIA: A meta-analysis.

Seiler A, Camilo M, Korostovtseva L, Haynes AG, Brill AK, Horvath T, Egger M, Bassetti CL.

Neurology. 2019 Feb 12;92(7):e648-e654. doi: 10.1212/WNL.0000000000006904. Epub 2019 Jan 11.


Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells.

Noy PJ, Gavin RL, Colombo D, Haining EJ, Reyat JS, Payne H, Thielmann I, Lokman AB, Neag G, Yang J, Lloyd T, Harrison N, Heath VL, Gardiner C, Whitworth KM, Robinson J, Koo CZ, Di Maio A, Harrison P, Lee SP, Michelangeli F, Kalia N, Rainger GE, Nieswandt B, Brill A, Watson SP, Tomlinson MG.

Haematologica. 2019 Sep;104(9):1892-1905. doi: 10.3324/haematol.2018.194241. Epub 2018 Dec 20.


Sleep-Wake Disorders in Stroke-Increased Stroke Risk and Deteriorated Recovery? An Evaluation on the Necessity for Prevention and Treatment.

Duss SB, Brill AK, Bargiotas P, Facchin L, Alexiev F, Manconi M, Bassetti CL.

Curr Neurol Neurosci Rep. 2018 Sep 7;18(10):72. doi: 10.1007/s11910-018-0879-6. Review.


To switch or not to switch: Intentions to switch to injectable PrEP among gay and bisexual men with at least twelve months oral PrEP experience.

Meyers K, Wu Y, Brill A, Sandfort T, Golub SA.

PLoS One. 2018 Jul 19;13(7):e0200296. doi: 10.1371/journal.pone.0200296. eCollection 2018.


Immune checkpoint inhibitors and radiosurgery for newly diagnosed melanoma brain metastases.

Robin TP, Breeze RE, Smith DE, Rusthoven CG, Lewis KD, Gonzalez R, Brill A, Saiki R, Stuhr K, Gaspar LE, Karam SD, Raben D, Kavanagh BD, Nath SK, Liu AK.

J Neurooncol. 2018 Oct;140(1):55-62. doi: 10.1007/s11060-018-2930-5. Epub 2018 Jun 16.


Immune Factors in Deep Vein Thrombosis Initiation.

Budnik I, Brill A.

Trends Immunol. 2018 Aug;39(8):610-623. doi: 10.1016/ Epub 2018 May 16. Review.


Mask pressure effects on the nasal bridge during short-term noninvasive ventilation.

Brill AK, Pickersgill R, Moghal M, Morrell MJ, Simonds AK.

ERJ Open Res. 2018 Apr 9;4(2). pii: 00168-2017. doi: 10.1183/23120541.00168-2017. eCollection 2018 Apr.


Prevalence and Prediction of Obstructive Sleep Apnea Prior to Bariatric Surgery-Gender-Specific Performance of Four Sleep Questionnaires.

Horvath CM, Jossen J, Kröll D, Nett PC, Baty F, Brill AK, Ott SR.

Obes Surg. 2018 Sep;28(9):2720-2726. doi: 10.1007/s11695-018-3222-z.


Four-year Survival (and Counting) after Stereotactic Radiosurgery to Nearly 100 Brain Metastases: A Case Report.

Saiki R, Brill A, Breeze RE.

Cureus. 2018 Jan 23;10(1):e2103. doi: 10.7759/cureus.2103.


CPAP as treatment of sleep apnea after stroke: A meta-analysis of randomized trials.

Brill AK, Horvath T, Seiler A, Camilo M, Haynes AG, Ott SR, Egger M, Bassetti CL.

Neurology. 2018 Apr 3;90(14):e1222-e1230. doi: 10.1212/WNL.0000000000005262. Epub 2018 Mar 9.


Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis.

Payne H, Brill A.

J Vis Exp. 2017 Dec 22;(130). doi: 10.3791/56697.


Cardiac βarrestin2 Improves Contractility and Adverse Remodeling in Heart Failure, But Is Underexpressed in Humans.

McCrink KA, Maning J, Vu A, Jafferjee M, Marrero C, Brill A, Bathgate-Siryk A, Dabul S, Koch WJ, Lymperopoulos A.

J Am Coll Cardiol. 2017 Dec 12;70(23):2948-2949. doi: 10.1016/j.jacc.2017.10.008. No abstract available.


Novel insights in cough and breathing patterns of patients with idiopathic pulmonary fibrosis performing repeated 24-hour-respiratory polygraphies.

Schertel A, Funke-Chambour M, Geiser T, Brill AK.

Respir Res. 2017 Nov 13;18(1):190. doi: 10.1186/s12931-017-0674-y.


β-Arrestin2 Improves Post-Myocardial Infarction Heart Failure via Sarco(endo)plasmic Reticulum Ca2+-ATPase-Dependent Positive Inotropy in Cardiomyocytes.

McCrink KA, Maning J, Vu A, Jafferjee M, Marrero C, Brill A, Bathgate-Siryk A, Dabul S, Koch WJ, Lymperopoulos A.

Hypertension. 2017 Nov;70(5):972-981. doi: 10.1161/HYPERTENSIONAHA.117.09817. Epub 2017 Sep 5.


EMX2 gene expression predicts liver metastasis and survival in colorectal cancer.

Aykut B, Ochs M, Radhakrishnan P, Brill A, Höcker H, Schwarz S, Weissinger D, Kehm R, Kulu Y, Ulrich A, Schneider M.

BMC Cancer. 2017 Aug 22;17(1):555. doi: 10.1186/s12885-017-3556-2.


Modelling and simulation of flow and agglomeration in deep veins valves using discrete multi physics.

Ariane M, Wen W, Vigolo D, Brill A, Nash FGB, Barigou M, Alexiadis A.

Comput Biol Med. 2017 Oct 1;89:96-103. doi: 10.1016/j.compbiomed.2017.07.020. Epub 2017 Jul 29.


A 58-Year-Old Man With Position-Dependent Nocturnal Dyspnea.

Schertel A, Horvath CM, Pichler Hefti J, Aubert JD, Brill AK.

Chest. 2017 Aug;152(2):e51-e55. doi: 10.1016/j.chest.2017.03.014.


The SERVE-HF safety notice in clinical practice - experiences of a tertiary sleep center.

Brill AK, Pichler Hefti J, Geiser T, Ott SR.

Sleep Med. 2017 Sep;37:201-207. doi: 10.1016/j.sleep.2017.02.007. Epub 2017 Mar 6.


Corrigendum: Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming.

Moreau T, Evans AL, Vasquez L, Tijssen MR, Yan Y, Trotter MW, Howard D, Colzani M, Arumugam M, Wu WH, Dalby A, Lampela R, Bouet G, Hobbs CM, Pask DC, Payne H, Ponomaryov T, Brill A, Soranzo N, Ouwehand WH, Pedersen RA, Ghevaert C.

Nat Commun. 2017 Jul 28;8:15076. doi: 10.1038/ncomms15076.


Lessons for Patient Education Around Long-Acting Injectable PrEP: Findings from a Mixed-Method Study of Phase II Trial Participants.

Meyers K, Rodriguez K, Brill AL, Wu Y, La Mar M, Dunbar D, Koblin B, Margolis D, Sobieszczyk ME, Van Tieu H, Frank I, Markowitz M, Golub SA.

AIDS Behav. 2018 Apr;22(4):1209-1216. doi: 10.1007/s10461-017-1871-x.


Mast Cells Granular Contents Are Crucial for Deep Vein Thrombosis in Mice.

Ponomaryov T, Payne H, Fabritz L, Wagner DD, Brill A.

Circ Res. 2017 Sep 29;121(8):941-950. doi: 10.1161/CIRCRESAHA.117.311185. Epub 2017 Jul 24.


Sleep-disordered breathing: clinical features, pathophysiology and diagnosis.

Ott SR, Korostovtseva L, Schmidt M, Horvath T, Brill AK, Bassetti CL.

Swiss Med Wkly. 2017 May 22;147:w14436. doi: 10.4414/smw.2017.14436. eCollection 2017.


Randomized crossover trial of a pressure sensing visual feedback system to improve mask fitting in noninvasive ventilation.

Brill AK, Moghal M, Morrell MJ, Simonds AK.

Respirology. 2017 Oct;22(7):1343-1349. doi: 10.1111/resp.13074. Epub 2017 May 15.


The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice.

Fenske RJ, Cadena MT, Harenda QE, Wienkes HN, Carbajal K, Schaid MD, Laundre E, Brill AL, Truchan NA, Brar H, Wisinski J, Cai J, Graham TE, Engin F, Kimple ME.

Endocrinology. 2017 Jun 1;158(6):1645-1658. doi: 10.1210/en.2016-1700.


Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-Cell Function.

Neuman JC, Schaid MD, Brill AL, Fenske RJ, Kibbe CR, Fontaine DA, Sdao SM, Brar HK, Connors KM, Wienkes HN, Eliceiri KW, Merrins MJ, Davis DB, Kimple ME.

Diabetes. 2017 Jun;66(6):1572-1585. doi: 10.2337/db16-1362. Epub 2017 Feb 13.


Mice with a deficiency in CLEC-2 are protected against deep vein thrombosis.

Payne H, Ponomaryov T, Watson SP, Brill A.

Blood. 2017 Apr 6;129(14):2013-2020. doi: 10.1182/blood-2016-09-742999. Epub 2017 Jan 19.


A 43-Year-Old Man With Daytime Sleepiness and a Heart Murmur.

Horvath CM, Zbinden S, Ott SR, Brill AK.

Chest. 2016 Oct;150(4):e117-e120. doi: 10.1016/j.chest.2016.03.039.


Initial Experience With a Novel Bipolar Hysteroscopic Tissue Removal System: A pilot Study Using the Symphion® System to Perform Office Polypectomy and Myomectomy.

Garcia AL, Brill AI.

J Minim Invasive Gynecol. 2015 Nov-Dec;22(6S):S114-S115. doi: 10.1016/j.jmig.2015.08.307. Epub 2015 Oct 15. No abstract available.


β1-adrenoceptor Arg389Gly polymorphism confers differential β-arrestin-binding tropism in cardiac myocytes.

McCrink KA, Brill A, Jafferjee M, Valero TR, Marrero C, Rodriguez MM, Hale GM, Lymperopoulos A.

Pharmacogenomics. 2016 Oct;17(15):1611-1620. Epub 2016 Sep 19.


Mounted Smartphones as Measurement and Control Platforms for Motor-Based Laboratory Test-Beds.

Frank JA, Brill A, Kapila V.

Sensors (Basel). 2016 Aug 20;16(8). pii: E1331. doi: 10.3390/s16081331.


Longitudinal Positron Emission Tomography in Preventive Alzheimer's Disease Drug Trials, Critical Barriers from Imaging Science Perspective.

Shokouhi S, Campbell D, Brill AB, Gwirtsman HE; Alzheimer's Disease Neuroimaging Initiative.

Brain Pathol. 2016 Sep;26(5):664-71. doi: 10.1111/bpa.12399.


Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice.

Shaw MA, Kombrinck KW, McElhinney KE, Sweet DR, Flick MJ, Palumbo JS, Cheng M, Esmon NL, Esmon CT, Brill A, Wagner DD, Degen JL, Mullins ES.

Blood. 2016 Aug 4;128(5):721-31. doi: 10.1182/blood-2015-11-680280. Epub 2016 Jun 1.

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