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Items: 1 to 50 of 361

1.

Sputum microbiome profiling in COPD: beyond singular pathogen detection.

Ditz B, Christenson S, Rossen J, Brightling C, Kerstjens HAM, van den Berge M, Faiz A.

Thorax. 2020 Jan 29. pii: thoraxjnl-2019-214168. doi: 10.1136/thoraxjnl-2019-214168. [Epub ahead of print]

2.

Managing Chronic Cough due to Asthma and NAEB in Adults and Adolescents: CHEST Guideline and Expert Panel Report.

Côté A, Russell RJ, Boulet LP, Gibson PG, Lai K, Irwin RS, Brightling CE; CHEST Expert Cough Panel.

Chest. 2020 Jan 20. pii: S0012-3692(20)30045-3. doi: 10.1016/j.chest.2019.12.021. [Epub ahead of print]

PMID:
31972181
3.

Clinical utility of fractional exhaled nitric oxide (FeNO) in severe asthma management.

Menzies-Gow A, Mansur AH, Brightling CE.

Eur Respir J. 2020 Jan 16. pii: 1901633. doi: 10.1183/13993003.01633-2019. [Epub ahead of print] Review.

PMID:
31949116
4.

The stability of blood Eosinophils in chronic obstructive pulmonary disease.

Long GH, Southworth T, Kolsum U, Donaldson GC, Wedzicha JA, Brightling CE, Singh D.

Respir Res. 2020 Jan 10;21(1):15. doi: 10.1186/s12931-020-1279-4.

5.

High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls.

Thun GA, Derdak S, Castro-Giner F, Apunte-Ramos K, Águeda L, Wjst M, Boland A, Deleuze JF, Kolsum U, Heiss-Neumann MS, Nowinski A, Gorecka D, Hohlfeld JM, Welte T, Brightling CE, Parr DG, Prasse A, Müller-Quernheim J, Greulich T, Stendardo M, Boschetto P, Barta I, Döme B, Gut M, Singh D, Ziegler-Heitbrock L, Gut IG.

Sci Rep. 2019 Dec 27;9(1):20158. doi: 10.1038/s41598-019-56618-1.

6.

Asthma exacerbations during pregnancy: A need for precision medicine.

Brightling CE.

Respirology. 2019 Dec 16. doi: 10.1111/resp.13761. [Epub ahead of print] No abstract available.

7.

Tensin1 expression and function in chronic obstructive pulmonary disease.

Stylianou P, Clark K, Gooptu B, Smallwood D, Brightling CE, Amrani Y, Roach KM, Bradding P.

Sci Rep. 2019 Dec 12;9(1):18942. doi: 10.1038/s41598-019-55405-2.

8.

Fatty airways: a source of good and bad fats?

Brightling CE, Tobin AB, Milligan G.

Eur Respir J. 2019 Dec 12;54(6). pii: 1902060. doi: 10.1183/13993003.02060-2019. Print 2019 Dec. No abstract available.

PMID:
31831675
9.

Increased ventilation heterogeneity in asthma can be attributed to proximal bronchioles.

Foy B, Kay D, Siddiqui S, Brightling C, Paiva M, Verbanck S.

Eur Respir J. 2019 Dec 5. pii: 1901345. doi: 10.1183/13993003.01345-2019. [Epub ahead of print] No abstract available.

PMID:
31806713
10.

Assessing causal treatment effect estimation when using large observational datasets.

John ER, Abrams KR, Brightling CE, Sheehan NA.

BMC Med Res Methodol. 2019 Nov 14;19(1):207. doi: 10.1186/s12874-019-0858-x.

11.

Resistome analyses of sputum from COPD and healthy subjects reveals bacterial load-related prevalence of target genes.

Ramsheh MY, Haldar K, Bafadhel M, George L, Free RC, John C, Reeve NF, Ziegler-Heitbrock L, Gut I, Singh D, Mistry V, Tobin MD, Oggioni MR, Brightling C, Barer MR.

Thorax. 2020 Jan;75(1):8-16. doi: 10.1136/thoraxjnl-2019-213485. Epub 2019 Nov 7.

PMID:
31699806
12.

Comment on "Unraveling a Clinical Paradox: Why Does Bronchial Thermoplasty Work in Asthma?"

Brook BS, Chernyavsky IL, Russell RJ, Saunders RM, Brightling CE.

Am J Respir Cell Mol Biol. 2019 Nov;61(5):660-661. doi: 10.1165/rcmb.2019-0095LE. No abstract available.

PMID:
31674824
13.

Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline.

Holguin F, Cardet JC, Chung KF, Diver S, Ferreira DS, Fitzpatrick A, Gaga M, Kellermeyer L, Khurana S, Knight S, McDonald VM, Morgan RL, Ortega VE, Rigau D, Subbarao P, Tonia T, Adcock IM, Bleecker ER, Brightling C, Boulet LP, Cabana M, Castro M, Chanez P, Custovic A, Djukanovic R, Frey U, Frankemölle B, Gibson P, Hamerlijnck D, Jarjour N, Konno S, Shen H, Vitary C, Bush A.

Eur Respir J. 2020 Jan 2;55(1). pii: 1900588. doi: 10.1183/13993003.00588-2019. Print 2020 Jan.

PMID:
31558662
14.

Sputum microbiomic clustering in asthma and COPD reveals a Haemophilus-predominant subgroup.

Diver S, Richardson M, Haldar K, Ghebre MA, Ramsheh MY, Bafadhel M, Desai D, Cohen ES, Newbold P, Rapley L, Rugman P, Pavord ID, May RD, Barer M, Brightling CE.

Allergy. 2019 Sep 25. doi: 10.1111/all.14058. [Epub ahead of print]

PMID:
31556120
15.

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases.

Bousquet JJ, Schünemann HJ, Togias A, Erhola M, Hellings PW, Zuberbier T, Agache I, Ansotegui IJ, Anto JM, Bachert C, Becker S, Bedolla-Barajas M, Bewick M, Bosnic-Anticevich S, Bosse I, Boulet LP, Bourrez JM, Brusselle G, Chavannes N, Costa E, Cruz AA, Czarlewski W, Fokkens WJ, Fonseca JA, Gaga M, Haahtela T, Illario M, Klimek L, Kuna P, Kvedariene V, Le LTT, Larenas-Linnemann D, Laune D, Lourenço OM, Menditto E, Mullol J, Okamoto Y, Papadopoulos N, Pham-Thi N, Picard R, Pinnock H, Roche N, Roller-Wirnsberger RE, Rolland C, Samolinski B, Sheikh A, Toppila-Salmi S, Tsiligianni I, Valiulis A, Valovirta E, Vasankari T, Ventura MT, Walker S, Williams S, Akdis CA, Annesi-Maesano I, Arnavielhe S, Basagana X, Bateman E, Bedbrook A, Bennoor KS, Benveniste S, Bergmann KC, Bialek S, Billo N, Bindslev-Jensen C, Bjermer L, Blain H, Bonini M, Bonniaud P, Bouchard J, Briedis V, Brightling CE, Brozek J, Buhl R, Buonaiuto R, Canonica GW, Cardona V, Carriazo AM, Carr W, Cartier C, Casale T, Cecchi L, Cepeda Sarabia AM, Chkhartishvili E, Chu DK, Cingi C, Colgan E, de Sousa JC, Courbis AL, Custovic A, Cvetkosvki B, D'Amato G, da Silva J, Dantas C, Dokic D, Dauvilliers Y, Dedeu A, De Feo G, Devillier P, Di Capua S, Dykewickz M, Dubakiene R, Ebisawa M, El-Gamal Y, Eller E, Emuzyte R, Farrell J, Fink-Wagner A, Fiocchi A, Fontaine JF, Gemicioğlu B, Schmid-Grendelmeir P, Gamkrelidze A, Garcia-Aymerich J, Gomez M, González Diaz S, Gotua M, Guldemond NA, Guzmán MA, Hajjam J, O'B Hourihane J, Humbert M, Iaccarino G, Ierodiakonou D, Illario M, Ivancevich JC, Joos G, Jung KS, Jutel M, Kaidashev I, Kalayci O, Kardas P, Keil T, Khaitov M, Khaltaev N, Kleine-Tebbe J, Kowalski ML, Kritikos V, Kull I, Leonardini L, Lieberman P, Lipworth B, Lodrup Carlsen KC, Loureiro CC, Louis R, Mair A, Marien G, Mahboub B, Malva J, Manning P, De Manuel Keenoy E, Marshall GD, Masjedi MR, Maspero JF, Mathieu-Dupas E, Matricardi PM, Melén E, Melo-Gomes E, Meltzer EO, Menditto E, Mercier J, Miculinic N, Mihaltan F, Milenkovic B, Moda G, Mogica-Martinez MD, Mohammad Y, Montefort S, Monti R, Morais-Almeida M, Mösges R, Münter L, Muraro A, Murray R, Naclerio R, Napoli L, Namazova-Baranova L, Neffen H, Nekam K, Neou A, Novellino E, Nyembue D, O'Hehir R, Ohta K, Okubo K, Onorato G, Ouedraogo S, Pali-Schöll I, Palkonen S, Panzner P, Park HS, Pépin JL, Pereira AM, Pfaar O, Paulino E, Phillips J, Picard R, Plavec D, Popov TA, Portejoie F, Price D, Prokopakis EP, Pugin B, Raciborski F, Rajabian-Söderlund R, Reitsma S, Rodo X, Romano A, Rosario N, Rottem M, Ryan D, Salimäki J, Sanchez-Borges MM, Sisul JC, Solé D, Somekh D, Sooronbaev T, Sova M, Spranger O, Stellato C, Stelmach R, Suppli Ulrik C, Thibaudon M, To T, Todo-Bom A, Tomazic PV, Valero AA, Valenta R, Valentin-Rostan M, van der Kleij R, Vandenplas O, Vezzani G, Viart F, Viegi G, Wallace D, Wagenmann M, Wang Y, Waserman S, Wickman M, Williams DM, Wong G, Wroczynski P, Yiallouros PK, Yorgancioglu A, Yusuf OM, Zar HJ, Zeng S, Zernotti M, Zhang L, Zhong NS, Zidarn M; ARIA Study Group; MASK Study Group.

Clin Transl Allergy. 2019 Sep 9;9:44. doi: 10.1186/s13601-019-0279-2. eCollection 2019. Review.

16.

Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.

George L, Taylor AR, Esteve-Codina A, Soler Artigas M, Thun GA, Bates S, Pavlidis S, Wagers S, Boland A, Prasse A, Boschetto P, Parr DG, Nowinski A, Barta I, Hohlfeld J, Greulich T, van den Berge M, Hiemstra PS, Timens W, Hinks T, Wenzel S, Siddiqui S, Richardson M, Venge P, Heath S, Gut I, Tobin MD, Edwards L, Riley JH, Djukanovic R, Auffray C, De-Meulder B, Erik-Dahlen S, Adcock IM, Chung KF, Ziegler-Heitbrock L, Sterk PJ, Singh D, Brightling CE; U-BIOPRED and the EvA study teams.

Allergy. 2019 Sep 10. doi: 10.1111/all.14016. [Epub ahead of print]

PMID:
31506971
17.

The ERS fellowship portfolio: fostering excellence and diversity.

Morty RE, Donnelly LE, Stolz D, Roche N, Welte T, Forrest KA, Brightling CE, Brusselle GG.

Eur Respir J. 2019 Sep 5;54(3). pii: 1901503. doi: 10.1183/13993003.01503-2019. Print 2019 Sep. No abstract available.

PMID:
31488590
18.

Small airways dysfunction: is there any involvement in patients with atopy? - Authors' reply.

Kraft M, Brightling C, Postma D.

Lancet Respir Med. 2019 Sep;7(9):e27. doi: 10.1016/S2213-2600(19)30248-6. No abstract available.

PMID:
31486395
19.

ERS/EAACI statement on severe exacerbations in asthma in adults: facts, priorities and key research questions.

Bourdin A, Bjermer L, Brightling C, Brusselle GG, Chanez P, Chung KF, Custovic A, Diamant Z, Diver S, Djukanovic R, Hamerlijnck D, Horváth I, Johnston SL, Kanniess F, Papadopoulos N, Papi A, Russell RJ, Ryan D, Samitas K, Tonia T, Zervas E, Gaga M.

Eur Respir J. 2019 Sep 28;54(3). pii: 1900900. doi: 10.1183/13993003.00900-2019. Print 2019 Sep.

PMID:
31467120
20.

Non-typeable Haemophilus influenzae protein vaccine in adults with COPD: A phase 2 clinical trial.

Wilkinson TMA, Schembri S, Brightling C, Bakerly ND, Lewis K, MacNee W, Rombo L, Hedner J, Allen M, Walker PP, De Ryck I, Tasciotti A, Casula D, Moris P, Testa M, Arora AK.

Vaccine. 2019 Sep 24;37(41):6102-6111. doi: 10.1016/j.vaccine.2019.07.100. Epub 2019 Aug 22.

21.

Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum.

Ghebre MA, Pang PH, Desai D, Hargadon B, Newby C, Woods J, Rapley L, Cohen SE, Herath A, Gaillard EA, May RD, Brightling CE.

BMC Pulm Med. 2019 Aug 8;19(1):144. doi: 10.1186/s12890-019-0906-7.

22.

Computational modelling prediction and clinical validation of impact of benralizumab on airway smooth muscle mass in asthma.

Chachi L, Diver S, Kaul H, Rebelatto MC, Boutrin A, Nisa P, Newbold P, Brightling C.

Eur Respir J. 2019 Nov 14;54(5). pii: 1900930. doi: 10.1183/13993003.00930-2019. Print 2019 Nov. No abstract available.

PMID:
31391226
23.

Cohort profile: Extended Cohort for E-health, Environment and DNA (EXCEED).

John C, Reeve NF, Free RC, Williams AT, Ntalla I, Farmaki AE, Bethea J, Barton LM, Shrine N, Batini C, Packer R, Terry S, Hargadon B, Wang Q, Melbourne CA, Adams EL, Bee CE, Harrington K, Miola J, Brunskill NJ, Brightling CE, Barwell J, Wallace SE, Hsu R, Shepherd DJ, Hollox EJ, Wain LV, Tobin MD.

Int J Epidemiol. 2019 Oct 1;48(5):1734. doi: 10.1093/ije/dyz175. No abstract available.

24.

Neutrophil elastase as a biomarker for bacterial infection in COPD.

Thulborn SJ, Mistry V, Brightling CE, Moffitt KL, Ribeiro D, Bafadhel M.

Respir Res. 2019 Jul 30;20(1):170. doi: 10.1186/s12931-019-1145-4.

25.

The impact of the prostaglandin D2 receptor 2 and its downstream effects on the pathophysiology of asthma.

Brightling CE, Brusselle G, Altman P.

Allergy. 2019 Jul 29. doi: 10.1111/all.14001. [Epub ahead of print] Review.

PMID:
31355946
26.

Cough and Eosinophilia.

Diver S, Russell RJ, Brightling CE.

J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):1740-1747. doi: 10.1016/j.jaip.2019.04.048.

PMID:
31279462
27.

Sputum Streptococcus pneumoniae is reduced in COPD following treatment with benralizumab.

George L, Wright A, Mistry V, Sutcliffe A, Chachi L, Haldar K, Ramsheh MY, Richardson M, van der Merwe R, Martin U, Newbold P, Brightling CE.

Int J Chron Obstruct Pulmon Dis. 2019 Jun 5;14:1177-1185. doi: 10.2147/COPD.S198302. eCollection 2019.

28.

Benralizumab for the Prevention of COPD Exacerbations.

Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D, Sin DD, Vogelmeier CF, Sciurba FC, Bafadhel M, Backer V, Kato M, Ramírez-Venegas A, Wei YF, Bjermer L, Shih VH, Jison M, O'Quinn S, Makulova N, Newbold P, Goldman M, Martin UJ; GALATHEA Study Investigators; TERRANOVA Study Investigators.

N Engl J Med. 2019 Sep 12;381(11):1023-1034. doi: 10.1056/NEJMoa1905248. Epub 2019 May 20.

PMID:
31112385
29.

Lung Computational Models and the Role of the Small Airways in Asthma.

Foy BH, Soares M, Bordas R, Richardson M, Bell A, Singapuri A, Hargadon B, Brightling C, Burrowes K, Kay D, Owers-Bradley J, Siddiqui S.

Am J Respir Crit Care Med. 2019 Oct 15;200(8):982-991. doi: 10.1164/rccm.201812-2322OC.

PMID:
31106566
30.

Mepolizumab does not alter the blood basophil count in severe asthma.

Wright AKA, Diver S, McCarthy J, Marvin A, Soares M, Thornton T, Bourne M, Craner M, Evans H, Edwards S, Glover S, Carr L, Parker S, Siddiqui S, Cousins D, Brightling C.

Allergy. 2019 Dec;74(12):2488-2490. doi: 10.1111/all.13879. Epub 2019 Jun 28. No abstract available.

31.

T2 Biologics for Chronic Obstructive Pulmonary Disease.

Yousuf A, Ibrahim W, Greening NJ, Brightling CE.

J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1405-1416. doi: 10.1016/j.jaip.2019.01.036.

PMID:
31076058
32.

Airway inflammation in COPD: progress to precision medicine.

Brightling C, Greening N.

Eur Respir J. 2019 Aug 1;54(2). pii: 1900651. doi: 10.1183/13993003.00651-2019. Print 2019 Aug.

PMID:
31073084
33.

Cohort Profile: Extended Cohort for E-health, Environment and DNA (EXCEED).

John C, Reeve NF, Free RC, Williams AT, Ntalla I, Farmaki AE, Bethea J, Barton LM, Shrine N, Batini C, Packer R, Terry S, Hargadon B, Wang Q, Melbourne CA, Adams EL, Bee CE, Harrington K, Miola J, Brunskill NJ, Brightling CE, Barwell J, Wallace SE, Hsu R, Shepherd DJ, Hollox EJ, Wain LV, Tobin MD.

Int J Epidemiol. 2019 Jun 1;48(3):678-679j. doi: 10.1093/ije/dyz073. No abstract available. Erratum in: Int J Epidemiol. 2019 Oct 1;48(5):1734.

34.

Exploring the relevance and extent of small airways dysfunction in asthma (ATLANTIS): baseline data from a prospective cohort study.

Postma DS, Brightling C, Baldi S, Van den Berge M, Fabbri LM, Gagnatelli A, Papi A, Van der Molen T, Rabe KF, Siddiqui S, Singh D, Nicolini G, Kraft M; ATLANTIS study group.

Lancet Respir Med. 2019 May;7(5):402-416. doi: 10.1016/S2213-2600(19)30049-9. Epub 2019 Mar 12. Erratum in: Lancet Respir Med. 2019 Sep;7(9):e28.

PMID:
30876830
35.

Assessment of breath volatile organic compounds in acute cardiorespiratory breathlessness: a protocol describing a prospective real-world observational study.

Ibrahim W, Wilde M, Cordell R, Salman D, Ruszkiewicz D, Bryant L, Richardson M, Free RC, Zhao B, Yousuf A, White C, Russell R, Jones S, Patel B, Awal A, Phillips R, Fowkes G, McNally T, Foxon C, Bhatt H, Peltrini R, Singapuri A, Hargadon B, Suzuki T, Ng LL, Gaillard E, Beardsmore C, Ryanna K, Pandya H, Coates T, Monks PS, Greening N, Brightling CE, Thomas P, Siddiqui S.

BMJ Open. 2019 Mar 8;9(3):e025486. doi: 10.1136/bmjopen-2018-025486.

36.

DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment.

Saunders R, Kaul H, Berair R, Gonem S, Singapuri A, Sutcliffe AJ, Chachi L, Biddle MS, Kaur D, Bourne M, Pavord ID, Wardlaw AJ, Siddiqui SH, Kay RA, Brook BS, Smallwood RH, Brightling CE.

Sci Transl Med. 2019 Feb 13;11(479). pii: eaao6451. doi: 10.1126/scitranslmed.aao6451.

37.

Breath analysis by two-dimensional gas chromatography with dual flame ionisation and mass spectrometric detection - Method optimisation and integration within a large-scale clinical study.

Wilde MJ, Cordell RL, Salman D, Zhao B, Ibrahim W, Bryant L, Ruszkiewicz D, Singapuri A, Free RC, Gaillard EA, Beardsmore C, Thomas CLP, Brightling CE, Siddiqui S, Monks PS.

J Chromatogr A. 2019 Jun 7;1594:160-172. doi: 10.1016/j.chroma.2019.02.001. Epub 2019 Feb 5.

38.

Functional CT imaging for identification of the spatial determinants of small-airways disease in adults with asthma.

Bell AJ, Foy BH, Richardson M, Singapuri A, Mirkes E, van den Berge M, Kay D, Brightling C, Gorban AN, Galbán CJ, Siddiqui S.

J Allergy Clin Immunol. 2019 Jul;144(1):83-93. doi: 10.1016/j.jaci.2019.01.014. Epub 2019 Jan 22.

PMID:
30682455
39.

Comparison of CT ventilation imaging and hyperpolarised gas MRI: effects of breathing manoeuvre.

Tahir BA, Marshall H, Hughes PJC, Brightling CE, Collier G, Ireland RH, Wild JM.

Phys Med Biol. 2019 Mar 7;64(5):055013. doi: 10.1088/1361-6560/ab0145.

40.

Reply.

Farahi N, Loutsios C, Tregay N, Wright AKA, Berair R, Lok LSC, Gillett D, Cullum I, Simmonds RP, Summers C, Wong A, Solanki CK, Buscombe J, Pang PH, Thavakumar A, Peters AM, Brightling CE, Condliffe AM, Chilvers ER.

J Allergy Clin Immunol. 2019 Mar;143(3):1265-1266. doi: 10.1016/j.jaci.2018.11.026. Epub 2019 Jan 11. No abstract available.

PMID:
30639067
41.

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

Shrine N, Portelli MA, John C, Soler Artigas M, Bennett N, Hall R, Lewis J, Henry AP, Billington CK, Ahmad A, Packer RJ, Shaw D, Pogson ZEK, Fogarty A, McKeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Djukanovic R, Hankinson J, Niven R, Simpson A, Chung KF, Sterk PJ, Blakey JD, Adcock IM, Hu S, Guo Y, Obeidat M, Sin DD, van den Berge M, Nickle DC, Bossé Y, Tobin MD, Hall IP, Brightling CE, Wain LV, Sayers I.

Lancet Respir Med. 2019 Jan;7(1):20-34. doi: 10.1016/S2213-2600(18)30389-8. Epub 2018 Dec 11.

42.

Temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations: FAST.

McKeever T, Mortimer K, Bradshaw L, Haydock R, Pavord I, Higgins B, Walker S, Wilson A, Price D, Thomas M, Devereux G, Brightling C, Renwick C, Parrott S, Mitchell E, Duley L, Harrison T.

Health Technol Assess. 2018 Dec;22(70):1-82. doi: 10.3310/hta22700.

43.

Sputum Moraxella catarrhalis strains exhibit diversity within and between COPD subjects.

George LM, Haigh RD, Mistry V, Haldar K, Barer MR, Oggioni MR, Brightling CE.

Int J Chron Obstruct Pulmon Dis. 2018 Nov 8;13:3663-3667. doi: 10.2147/COPD.S180961. eCollection 2018.

44.

Exacerbations of severe asthma in patients treated with mepolizumab.

Shrimanker R, Pavord ID, Yancey S, Heaney LG, Green RH, Bradding P, Hargadon B, Brightling CE, Wardlaw AJ, Haldar P.

Eur Respir J. 2018 Dec 13;52(6). pii: 1801127. doi: 10.1183/13993003.01127-2018. Print 2018 Dec. No abstract available.

PMID:
30464012
45.

Face mask sampling reveals antimicrobial resistance genes in exhaled aerosols from patients with chronic obstructive pulmonary disease and healthy volunteers.

Kennedy M, Ramsheh MY, Williams CML, Auty J, Haldar K, Abdulwhhab M, Brightling CE, Barer MR.

BMJ Open Respir Res. 2018 Sep 23;5(1):e000321. doi: 10.1136/bmjresp-2018-000321. eCollection 2018.

46.

ERS Clinical Research Collaborations: underpinning research excellence.

Brightling C, Genton C, Bill W, Welte T, Gaga M, Heuvelin E, Brusselle G.

Eur Respir J. 2018 Sep 15;52(3). pii: 1801534. doi: 10.1183/13993003.01534-2018. Print 2018 Sep. No abstract available.

PMID:
30219755
47.

In vivo imaging reveals increased eosinophil uptake in the lungs of obese asthmatic patients.

Farahi N, Loutsios C, Tregay N, Wright AKA, Berair R, Lok LSC, Gillett D, Cullum I, Simmonds RP, Summers C, Wong A, Solanki CK, Buscombe J, Pang PH, Thavakumar A, Peters AM, Brightling CE, Condliffe AM, Chilvers ER.

J Allergy Clin Immunol. 2018 Nov;142(5):1659-1662.e8. doi: 10.1016/j.jaci.2018.07.011. Epub 2018 Jul 30. No abstract available.

48.

Urgent need for pragmatic trial platforms in severe asthma.

Pilette C, Brightling C, Lacombe D, Brusselle G.

Lancet Respir Med. 2018 Aug;6(8):581-583. doi: 10.1016/S2213-2600(18)30291-1. No abstract available.

PMID:
30070256
49.

Modelling the effect of gravity on inert-gas washout outputs.

Foy BH, Gonem S, Brightling C, Siddiqui S, Kay D.

Physiol Rep. 2018 May;6(10):e13709. doi: 10.14814/phy2.13709.

50.

Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial.

Russell RJ, Chachi L, FitzGerald JM, Backer V, Olivenstein R, Titlestad IL, Ulrik CS, Harrison T, Singh D, Chaudhuri R, Leaker B, McGarvey L, Siddiqui S, Wang M, Braddock M, Nordenmark LH, Cohen D, Parikh H, Colice G, Brightling CE; MESOS study investigators.

Lancet Respir Med. 2018 Jul;6(7):499-510. doi: 10.1016/S2213-2600(18)30201-7. Epub 2018 May 21.

PMID:
29793857

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