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Items: 1 to 50 of 347

1.

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases.

Bousquet JJ, Schünemann HJ, Togias A, Erhola M, Hellings PW, Zuberbier T, Agache I, Ansotegui IJ, Anto JM, Bachert C, Becker S, Bedolla-Barajas M, Bewick M, Bosnic-Anticevich S, Bosse I, Boulet LP, Bourrez JM, Brusselle G, Chavannes N, Costa E, Cruz AA, Czarlewski W, Fokkens WJ, Fonseca JA, Gaga M, Haahtela T, Illario M, Klimek L, Kuna P, Kvedariene V, Le LTT, Larenas-Linnemann D, Laune D, Lourenço OM, Menditto E, Mullol J, Okamoto Y, Papadopoulos N, Pham-Thi N, Picard R, Pinnock H, Roche N, Roller-Wirnsberger RE, Rolland C, Samolinski B, Sheikh A, Toppila-Salmi S, Tsiligianni I, Valiulis A, Valovirta E, Vasankari T, Ventura MT, Walker S, Williams S, Akdis CA, Annesi-Maesano I, Arnavielhe S, Basagana X, Bateman E, Bedbrook A, Bennoor KS, Benveniste S, Bergmann KC, Bialek S, Billo N, Bindslev-Jensen C, Bjermer L, Blain H, Bonini M, Bonniaud P, Bouchard J, Briedis V, Brightling CE, Brozek J, Buhl R, Buonaiuto R, Canonica GW, Cardona V, Carriazo AM, Carr W, Cartier C, Casale T, Cecchi L, Cepeda Sarabia AM, Chkhartishvili E, Chu DK, Cingi C, Colgan E, de Sousa JC, Courbis AL, Custovic A, Cvetkosvki B, D'Amato G, da Silva J, Dantas C, Dokic D, Dauvilliers Y, Dedeu A, De Feo G, Devillier P, Di Capua S, Dykewickz M, Dubakiene R, Ebisawa M, El-Gamal Y, Eller E, Emuzyte R, Farrell J, Fink-Wagner A, Fiocchi A, Fontaine JF, Gemicioğlu B, Schmid-Grendelmeir P, Gamkrelidze A, Garcia-Aymerich J, Gomez M, González Diaz S, Gotua M, Guldemond NA, Guzmán MA, Hajjam J, O'B Hourihane J, Humbert M, Iaccarino G, Ierodiakonou D, Illario M, Ivancevich JC, Joos G, Jung KS, Jutel M, Kaidashev I, Kalayci O, Kardas P, Keil T, Khaitov M, Khaltaev N, Kleine-Tebbe J, Kowalski ML, Kritikos V, Kull I, Leonardini L, Lieberman P, Lipworth B, Lodrup Carlsen KC, Loureiro CC, Louis R, Mair A, Marien G, Mahboub B, Malva J, Manning P, De Manuel Keenoy E, Marshall GD, Masjedi MR, Maspero JF, Mathieu-Dupas E, Matricardi PM, Melén E, Melo-Gomes E, Meltzer EO, Menditto E, Mercier J, Miculinic N, Mihaltan F, Milenkovic B, Moda G, Mogica-Martinez MD, Mohammad Y, Montefort S, Monti R, Morais-Almeida M, Mösges R, Münter L, Muraro A, Murray R, Naclerio R, Napoli L, Namazova-Baranova L, Neffen H, Nekam K, Neou A, Novellino E, Nyembue D, O'Hehir R, Ohta K, Okubo K, Onorato G, Ouedraogo S, Pali-Schöll I, Palkonen S, Panzner P, Park HS, Pépin JL, Pereira AM, Pfaar O, Paulino E, Phillips J, Picard R, Plavec D, Popov TA, Portejoie F, Price D, Prokopakis EP, Pugin B, Raciborski F, Rajabian-Söderlund R, Reitsma S, Rodo X, Romano A, Rosario N, Rottem M, Ryan D, Salimäki J, Sanchez-Borges MM, Sisul JC, Solé D, Somekh D, Sooronbaev T, Sova M, Spranger O, Stellato C, Stelmach R, Suppli Ulrik C, Thibaudon M, To T, Todo-Bom A, Tomazic PV, Valero AA, Valenta R, Valentin-Rostan M, van der Kleij R, Vandenplas O, Vezzani G, Viart F, Viegi G, Wallace D, Wagenmann M, Wang Y, Waserman S, Wickman M, Williams DM, Wong G, Wroczynski P, Yiallouros PK, Yorgancioglu A, Yusuf OM, Zar HJ, Zeng S, Zernotti M, Zhang L, Zhong NS, Zidarn M; ARIA Study Group; MASK Study Group.

Clin Transl Allergy. 2019 Sep 9;9:44. doi: 10.1186/s13601-019-0279-2. eCollection 2019. Review.

2.

Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.

George L, Taylor AR, Esteve-Codina A, Soler Artigas M, Thun GA, Bates S, Pavlidis S, Wagers S, Boland A, Prasse A, Boschetto P, Parr DG, Nowinski A, Barta I, Hohlfeld J, Greulich T, van den Berge M, Hiemstra PS, Timens W, Hinks T, Wenzel S, Siddiqui S, Richardson M, Venge P, Heath S, Gut I, Tobin MD, Edwards L, Riley JH, Djukanovic R, Auffray C, De-Meulder B, Erik-Dahlen S, Adcock IM, Chung KF, Ziegler-Heitbrock L, Sterk PJ, Singh D, Brightling CE; U-BIOPRED and the EvA study teams.

Allergy. 2019 Sep 10. doi: 10.1111/all.14016. [Epub ahead of print]

PMID:
31506971
3.

The ERS fellowship portfolio: fostering excellence and diversity.

Morty RE, Donnelly LE, Stolz D, Roche N, Welte T, Forrest KA, Brightling CE, Brusselle GG.

Eur Respir J. 2019 Sep 5;54(3). pii: 1901503. doi: 10.1183/13993003.01503-2019. Print 2019 Sep. No abstract available.

PMID:
31488590
4.

Small airways dysfunction: is there any involvement in patients with atopy? - Authors' reply.

Kraft M, Brightling C, Postma D.

Lancet Respir Med. 2019 Sep;7(9):e27. doi: 10.1016/S2213-2600(19)30248-6. No abstract available.

PMID:
31486395
5.

ERS/EAACI Statement on severe exacerbations in asthma in adult: facts, priorities and key research questions.

Bourdin A, Bjermer L, Brightling C, Brusselle G, Chanez P, Chung F, Custovic A, Diamant Z, Diver S, Djukanovic R, Hamerlijnck D, Johnston S, Kanniess F, Papadopoulos N, Papi A, Russell R, Ryan D, Samitas K, Tonia T, Zervas E, Gaga M.

Eur Respir J. 2019 Sep 12. pii: 1900900. doi: 10.1183/13993003.00900-2019. [Epub ahead of print]

PMID:
31467120
6.

Non-typeable Haemophilus influenzae protein vaccine in adults with COPD: A phase 2 clinical trial.

Wilkinson TMA, Schembri S, Brightling C, Bakerly ND, Lewis K, MacNee W, Rombo L, Hedner J, Allen M, Walker PP, De Ryck I, Tasciotti A, Casula D, Moris P, Testa M, Arora AK.

Vaccine. 2019 Sep 24;37(41):6102-6111. doi: 10.1016/j.vaccine.2019.07.100. Epub 2019 Aug 22.

7.

Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum.

Ghebre MA, Pang PH, Desai D, Hargadon B, Newby C, Woods J, Rapley L, Cohen SE, Herath A, Gaillard EA, May RD, Brightling CE.

BMC Pulm Med. 2019 Aug 8;19(1):144. doi: 10.1186/s12890-019-0906-7.

8.

Computational modelling prediction and clinical validation of impact of benralizumab on airway smooth muscle mass in asthma.

Chachi L, Diver S, Kaul H, Rebelatto MC, Boutrin A, Nisa P, Newbold P, Brightling C.

Eur Respir J. 2019 Aug 7. pii: 1900930. doi: 10.1183/13993003.00930-2019. [Epub ahead of print] No abstract available.

PMID:
31391226
9.

Cohort profile: Extended Cohort for E-health, Environment and DNA (EXCEED).

John C, Reeve NF, Free RC, Williams AT, Ntalla I, Farmaki AE, Bethea J, Barton LM, Shrine N, Batini C, Packer R, Terry S, Hargadon B, Wang Q, Melbourne CA, Adams EL, Bee CE, Harrington K, Miola J, Brunskill NJ, Brightling CE, Barwell J, Wallace SE, Hsu R, Shepherd DJ, Hollox EJ, Wain LV, Tobin MD.

Int J Epidemiol. 2019 Jul 31. pii: dyz175. doi: 10.1093/ije/dyz175. [Epub ahead of print] No abstract available.

PMID:
31365084
10.

Neutrophil elastase as a biomarker for bacterial infection in COPD.

Thulborn SJ, Mistry V, Brightling CE, Moffitt KL, Ribeiro D, Bafadhel M.

Respir Res. 2019 Jul 30;20(1):170. doi: 10.1186/s12931-019-1145-4.

11.

The impact of the prostaglandin D2 receptor 2 and its downstream effects on the pathophysiology of asthma.

Brightling CE, Brusselle G, Altman P.

Allergy. 2019 Jul 29. doi: 10.1111/all.14001. [Epub ahead of print] Review.

PMID:
31355946
12.

Cough and Eosinophilia.

Diver S, Russell RJ, Brightling CE.

J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):1740-1747. doi: 10.1016/j.jaip.2019.04.048.

PMID:
31279462
13.

Sputum Streptococcus pneumoniae is reduced in COPD following treatment with benralizumab.

George L, Wright A, Mistry V, Sutcliffe A, Chachi L, Haldar K, Ramsheh MY, Richardson M, van der Merwe R, Martin U, Newbold P, Brightling CE.

Int J Chron Obstruct Pulmon Dis. 2019 Jun 5;14:1177-1185. doi: 10.2147/COPD.S198302. eCollection 2019.

14.

Benralizumab for the Prevention of COPD Exacerbations.

Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D, Sin DD, Vogelmeier CF, Sciurba FC, Bafadhel M, Backer V, Kato M, Ramírez-Venegas A, Wei YF, Bjermer L, Shih VH, Jison M, O'Quinn S, Makulova N, Newbold P, Goldman M, Martin UJ; GALATHEA and TERRANOVA Study Investigators; GALATHEA Study Investigators; TERRANOVA Study Investigators.

N Engl J Med. 2019 Sep 12;381(11):1023-1034. doi: 10.1056/NEJMoa1905248. Epub 2019 May 20.

PMID:
31112385
15.

Lung Computational Models and the Role of the Small Airways in Asthma.

Foy BH, Soares M, Bordas R, Richardson M, Bell A, Singapuri A, Hargadon B, Brightling C, Burrowes K, Kay D, Owers-Bradley J, Siddiqui S.

Am J Respir Crit Care Med. 2019 May 18. doi: 10.1164/rccm.201812-2322OC. [Epub ahead of print]

PMID:
31106566
16.

Mepolizumab does not alter the blood basophil count in severe asthma.

Wright AKA, Diver S, McCarthy J, Marvin A, Soares M, Thornton T, Bourne M, Craner M, Evans H, Edwards S, Glover S, Carr L, Parker S, Siddiqui S, Cousins D, Brightling C.

Allergy. 2019 May 20. doi: 10.1111/all.13879. [Epub ahead of print] No abstract available.

PMID:
31106444
17.

T2 Biologics for Chronic Obstructive Pulmonary Disease.

Yousuf A, Ibrahim W, Greening NJ, Brightling CE.

J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1405-1416. doi: 10.1016/j.jaip.2019.01.036.

PMID:
31076058
18.

Airway inflammation in COPD: progress to precision medicine.

Brightling C, Greening N.

Eur Respir J. 2019 Aug 1;54(2). pii: 1900651. doi: 10.1183/13993003.00651-2019. Print 2019 Aug.

PMID:
31073084
19.

Cohort Profile: Extended Cohort for E-health, Environment and DNA (EXCEED).

John C, Reeve NF, Free RC, Williams AT, Ntalla I, Farmaki AE, Bethea J, Barton LM, Shrine N, Batini C, Packer R, Terry S, Hargadon B, Wang Q, Melbourne CA, Adams EL, Bee CE, Harrington K, Miola J, Brunskill NJ, Brightling CE, Barwell J, Wallace SE, Hsu R, Shepherd DJ, Hollox EJ, Wain LV, Tobin MD.

Int J Epidemiol. 2019 Jun 1;48(3):678-679j. doi: 10.1093/ije/dyz073. No abstract available.

20.

Exploring the relevance and extent of small airways dysfunction in asthma (ATLANTIS): baseline data from a prospective cohort study.

Postma DS, Brightling C, Baldi S, Van den Berge M, Fabbri LM, Gagnatelli A, Papi A, Van der Molen T, Rabe KF, Siddiqui S, Singh D, Nicolini G, Kraft M; ATLANTIS study group.

Lancet Respir Med. 2019 May;7(5):402-416. doi: 10.1016/S2213-2600(19)30049-9. Epub 2019 Mar 12. Erratum in: Lancet Respir Med. 2019 Sep;7(9):e28.

PMID:
30876830
21.

Assessment of breath volatile organic compounds in acute cardiorespiratory breathlessness: a protocol describing a prospective real-world observational study.

Ibrahim W, Wilde M, Cordell R, Salman D, Ruszkiewicz D, Bryant L, Richardson M, Free RC, Zhao B, Yousuf A, White C, Russell R, Jones S, Patel B, Awal A, Phillips R, Fowkes G, McNally T, Foxon C, Bhatt H, Peltrini R, Singapuri A, Hargadon B, Suzuki T, Ng LL, Gaillard E, Beardsmore C, Ryanna K, Pandya H, Coates T, Monks PS, Greening N, Brightling CE, Thomas P, Siddiqui S.

BMJ Open. 2019 Mar 8;9(3):e025486. doi: 10.1136/bmjopen-2018-025486.

22.

DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment.

Saunders R, Kaul H, Berair R, Gonem S, Singapuri A, Sutcliffe AJ, Chachi L, Biddle MS, Kaur D, Bourne M, Pavord ID, Wardlaw AJ, Siddiqui SH, Kay RA, Brook BS, Smallwood RH, Brightling CE.

Sci Transl Med. 2019 Feb 13;11(479). pii: eaao6451. doi: 10.1126/scitranslmed.aao6451.

PMID:
30760581
23.

Breath analysis by two-dimensional gas chromatography with dual flame ionisation and mass spectrometric detection - Method optimisation and integration within a large-scale clinical study.

Wilde MJ, Cordell RL, Salman D, Zhao B, Ibrahim W, Bryant L, Ruszkiewicz D, Singapuri A, Free RC, Gaillard EA, Beardsmore C, Thomas CLP, Brightling CE, Siddiqui S, Monks PS.

J Chromatogr A. 2019 Jun 7;1594:160-172. doi: 10.1016/j.chroma.2019.02.001. Epub 2019 Feb 5.

24.

Functional CT imaging for identification of the spatial determinants of small-airways disease in adults with asthma.

Bell AJ, Foy BH, Richardson M, Singapuri A, Mirkes E, van den Berge M, Kay D, Brightling C, Gorban AN, Galbán CJ, Siddiqui S.

J Allergy Clin Immunol. 2019 Jul;144(1):83-93. doi: 10.1016/j.jaci.2019.01.014. Epub 2019 Jan 22.

PMID:
30682455
25.

Comparison of CT ventilation imaging and hyperpolarised gas MRI: effects of breathing manoeuvre.

Tahir BA, Marshall H, Hughes PJC, Brightling CE, Collier G, Ireland RH, Wild JM.

Phys Med Biol. 2019 Mar 7;64(5):055013. doi: 10.1088/1361-6560/ab0145.

PMID:
30673634
26.

Reply.

Farahi N, Loutsios C, Tregay N, Wright AKA, Berair R, Lok LSC, Gillett D, Cullum I, Simmonds RP, Summers C, Wong A, Solanki CK, Buscombe J, Pang PH, Thavakumar A, Peters AM, Brightling CE, Condliffe AM, Chilvers ER.

J Allergy Clin Immunol. 2019 Mar;143(3):1265-1266. doi: 10.1016/j.jaci.2018.11.026. Epub 2019 Jan 11. No abstract available.

PMID:
30639067
27.

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

Shrine N, Portelli MA, John C, Soler Artigas M, Bennett N, Hall R, Lewis J, Henry AP, Billington CK, Ahmad A, Packer RJ, Shaw D, Pogson ZEK, Fogarty A, McKeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Djukanovic R, Hankinson J, Niven R, Simpson A, Chung KF, Sterk PJ, Blakey JD, Adcock IM, Hu S, Guo Y, Obeidat M, Sin DD, van den Berge M, Nickle DC, Bossé Y, Tobin MD, Hall IP, Brightling CE, Wain LV, Sayers I.

Lancet Respir Med. 2019 Jan;7(1):20-34. doi: 10.1016/S2213-2600(18)30389-8. Epub 2018 Dec 11.

28.

Temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations: FAST.

McKeever T, Mortimer K, Bradshaw L, Haydock R, Pavord I, Higgins B, Walker S, Wilson A, Price D, Thomas M, Devereux G, Brightling C, Renwick C, Parrott S, Mitchell E, Duley L, Harrison T.

Health Technol Assess. 2018 Dec;22(70):1-82. doi: 10.3310/hta22700.

29.

Sputum Moraxella catarrhalis strains exhibit diversity within and between COPD subjects.

George LM, Haigh RD, Mistry V, Haldar K, Barer MR, Oggioni MR, Brightling CE.

Int J Chron Obstruct Pulmon Dis. 2018 Nov 8;13:3663-3667. doi: 10.2147/COPD.S180961. eCollection 2018.

30.

Exacerbations of severe asthma in patients treated with mepolizumab.

Shrimanker R, Pavord ID, Yancey S, Heaney LG, Green RH, Bradding P, Hargadon B, Brightling CE, Wardlaw AJ, Haldar P.

Eur Respir J. 2018 Dec 13;52(6). pii: 1801127. doi: 10.1183/13993003.01127-2018. Print 2018 Dec. No abstract available.

PMID:
30464012
31.

Face mask sampling reveals antimicrobial resistance genes in exhaled aerosols from patients with chronic obstructive pulmonary disease and healthy volunteers.

Kennedy M, Ramsheh MY, Williams CML, Auty J, Haldar K, Abdulwhhab M, Brightling CE, Barer MR.

BMJ Open Respir Res. 2018 Sep 23;5(1):e000321. doi: 10.1136/bmjresp-2018-000321. eCollection 2018.

32.

ERS Clinical Research Collaborations: underpinning research excellence.

Brightling C, Genton C, Bill W, Welte T, Gaga M, Heuvelin E, Brusselle G.

Eur Respir J. 2018 Sep 15;52(3). pii: 1801534. doi: 10.1183/13993003.01534-2018. Print 2018 Sep. No abstract available.

PMID:
30219755
33.

In vivo imaging reveals increased eosinophil uptake in the lungs of obese asthmatic patients.

Farahi N, Loutsios C, Tregay N, Wright AKA, Berair R, Lok LSC, Gillett D, Cullum I, Simmonds RP, Summers C, Wong A, Solanki CK, Buscombe J, Pang PH, Thavakumar A, Peters AM, Brightling CE, Condliffe AM, Chilvers ER.

J Allergy Clin Immunol. 2018 Nov;142(5):1659-1662.e8. doi: 10.1016/j.jaci.2018.07.011. Epub 2018 Jul 30. No abstract available.

34.

Urgent need for pragmatic trial platforms in severe asthma.

Pilette C, Brightling C, Lacombe D, Brusselle G.

Lancet Respir Med. 2018 Aug;6(8):581-583. doi: 10.1016/S2213-2600(18)30291-1. No abstract available.

PMID:
30070256
35.

Modelling the effect of gravity on inert-gas washout outputs.

Foy BH, Gonem S, Brightling C, Siddiqui S, Kay D.

Physiol Rep. 2018 May;6(10):e13709. doi: 10.14814/phy2.13709.

36.

Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial.

Russell RJ, Chachi L, FitzGerald JM, Backer V, Olivenstein R, Titlestad IL, Ulrik CS, Harrison T, Singh D, Chaudhuri R, Leaker B, McGarvey L, Siddiqui S, Wang M, Braddock M, Nordenmark LH, Cohen D, Parikh H, Colice G, Brightling CE; MESOS study investigators.

Lancet Respir Med. 2018 Jul;6(7):499-510. doi: 10.1016/S2213-2600(18)30201-7. Epub 2018 May 21.

PMID:
29793857
37.

Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials.

Panettieri RA Jr, Sjöbring U, Péterffy A, Wessman P, Bowen K, Piper E, Colice G, Brightling CE.

Lancet Respir Med. 2018 Jul;6(7):511-525. doi: 10.1016/S2213-2600(18)30184-X. Epub 2018 May 20.

PMID:
29792288
38.

Biological exacerbation clusters demonstrate asthma and chronic obstructive pulmonary disease overlap with distinct mediator and microbiome profiles.

Ghebre MA, Pang PH, Diver S, Desai D, Bafadhel M, Haldar K, Kebadze T, Cohen S, Newbold P, Rapley L, Woods J, Rugman P, Pavord ID, Johnston SL, Barer M, May RD, Brightling CE.

J Allergy Clin Immunol. 2018 Jun;141(6):2027-2036.e12. doi: 10.1016/j.jaci.2018.04.013. Epub 2018 Apr 28.

39.

In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss.

Chernyavsky IL, Russell RJ, Saunders RM, Morris GE, Berair R, Singapuri A, Chachi L, Mansur AH, Howarth PH, Dennison P, Chaudhuri R, Bicknell S, Rose FRAJ, Siddiqui S, Brook BS, Brightling CE.

Eur Respir J. 2018 May 24;51(5). pii: 1701680. doi: 10.1183/13993003.01680-2017. Print 2018 May.

40.

Biologic Drugs: A New Target Therapy in COPD?

Yousuf A, Brightling CE.

COPD. 2018 Apr;15(2):99-107. doi: 10.1080/15412555.2018.1437897. Epub 2018 Apr 23. Review.

PMID:
29683730
41.

Airway pathological heterogeneity in asthma: Visualization of disease microclusters using topological data analysis.

Siddiqui S, Shikotra A, Richardson M, Doran E, Choy D, Bell A, Austin CD, Eastham-Anderson J, Hargadon B, Arron JR, Wardlaw A, Brightling CE, Heaney LG, Bradding P.

J Allergy Clin Immunol. 2018 Nov;142(5):1457-1468. doi: 10.1016/j.jaci.2017.12.982. Epub 2018 Mar 14.

PMID:
29550052
42.

Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease Is Enhanced by Nrf2 Agonists.

Bewley MA, Budd RC, Ryan E, Cole J, Collini P, Marshall J, Kolsum U, Beech G, Emes RD, Tcherniaeva I, Berbers GAM, Walmsley SR, Donaldson G, Wedzicha JA, Kilty I, Rumsey W, Sanchez Y, Brightling CE, Donnelly LE, Barnes PJ, Singh D, Whyte MKB, Dockrell DH; COPDMAP.

Am J Respir Crit Care Med. 2018 Sep 15;198(6):739-750. doi: 10.1164/rccm.201705-0903OC.

43.

Quadrupling Inhaled Glucocorticoid Dose to Abort Asthma Exacerbations.

McKeever T, Mortimer K, Wilson A, Walker S, Brightling C, Skeggs A, Pavord I, Price D, Duley L, Thomas M, Bradshaw L, Higgins B, Haydock R, Mitchell E, Devereux G, Harrison T.

N Engl J Med. 2018 Mar 8;378(10):902-910. doi: 10.1056/NEJMoa1714257. Epub 2018 Mar 3.

44.

Advancing the management of obstructive airways diseases through translational research.

Porsbjerg C, Sverrild A, Baines KJ, Searles A, Maltby S, Foster PS, Brightling C, Gibson PG.

Clin Exp Allergy. 2018 May;48(5):493-501. doi: 10.1111/cea.13112. Epub 2018 Mar 13. Review.

PMID:
29412485
45.

Fevipiprant in the treatment of asthma.

White C, Wright A, Brightling C.

Expert Opin Investig Drugs. 2018 Feb;27(2):199-207. doi: 10.1080/13543784.2018.1432592. Epub 2018 Jan 30. Review.

PMID:
29363343
46.

New and emerging drug treatments for severe asthma.

Diver S, Russell RJ, Brightling CE.

Clin Exp Allergy. 2018 Mar;48(3):241-252. doi: 10.1111/cea.13086. Epub 2018 Feb 13. Review.

PMID:
29315966
47.

A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial.

Hanratty CE, Matthews JG, Arron JR, Choy DF, Pavord ID, Bradding P, Brightling CE, Chaudhuri R, Cowan DC, Djukanovic R, Gallagher N, Fowler SJ, Hardman TC, Harrison T, Holweg CT, Howarth PH, Lordan J, Mansur AH, Menzies-Gow A, Mosesova S, Niven RM, Robinson DS, Shaw DE, Walker S, Woodcock A, Heaney LG; RASP-UK (Refractory Asthma Stratification Programme) Consortium.

Trials. 2018 Jan 4;19(1):5. doi: 10.1186/s13063-017-2384-7.

48.

Big asthma data: getting bigger and more beautiful?

Diver S, Brightling CE.

Thorax. 2018 Apr;73(4):311-312. doi: 10.1136/thoraxjnl-2017-211148. Epub 2017 Dec 29. No abstract available.

PMID:
29288213
49.

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

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Nat Genet. 2018 Jan;50(1):42-53. doi: 10.1038/s41588-017-0014-7. Epub 2017 Dec 22.

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Asthma.

Papi A, Brightling C, Pedersen SE, Reddel HK.

Lancet. 2018 Feb 24;391(10122):783-800. doi: 10.1016/S0140-6736(17)33311-1. Epub 2017 Dec 19. Review.

PMID:
29273246

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