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Items: 1 to 50 of 116

1.

Antibiotic Review Kit for Hospitals (ARK-Hospital): study protocol for a stepped-wedge cluster-randomised controlled trial.

Walker AS, Budgell E, Laskawiec-Szkonter M, Sivyer K, Wordsworth S, Quaddy J, Santillo M, Krusche A, Roope LSJ, Bright N, Mowbray F, Jones N, Hand K, Rahman N, Dobson M, Hedley E, Crook D, Sharland M, Roseveare C, Hobbs FDR, Butler C, Vaughan L, Hopkins S, Yardley L, Peto TEA, Llewelyn MJ; ARK trial team.

Trials. 2019 Jul 11;20(1):421. doi: 10.1186/s13063-019-3497-y.

2.

The lysosomal disease caused by mutant VPS33A.

Pavlova EV, Shatunov A, Wartosch L, Moskvina AI, Nikolaeva LE, Bright NA, Tylee KL, Church HJ, Ballabio A, Luzio JP, Cox TM.

Hum Mol Genet. 2019 Apr 10. pii: ddz077. doi: 10.1093/hmg/ddz077. [Epub ahead of print]

PMID:
31070736
3.

The Lysosome and Intracellular Signalling.

Hesketh GG, Wartosch L, Davis LJ, Bright NA, Luzio JP.

Prog Mol Subcell Biol. 2018;57:151-180. doi: 10.1007/978-3-319-96704-2_6. Review.

PMID:
30097775
4.

Mammalian γ2 AMPK regulates intrinsic heart rate.

Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M, Czibik G, Steeples V, Ghaffari S, Nguyen C, Stockenhuber A, Clair JRS, Rimmbach C, Okamoto Y, Yang D, Wang M, Ziman BD, Moen JM, Riordon DR, Ramirez C, Paina M, Lee J, Zhang J, Ahmet I, Matt MG, Tarasova YS, Baban D, Sahgal N, Lockstone H, Puliyadi R, de Bono J, Siggs OM, Gomes J, Muskett H, Maguire ML, Beglov Y, Kelly M, Dos Santos PPN, Bright NJ, Woods A, Gehmlich K, Isackson H, Douglas G, Ferguson DJP, Schneider JE, Tinker A, Wolkenhauer O, Channon KM, Cornall RJ, Sternick EB, Paterson DJ, Redwood CS, Carling D, Proenza C, David R, Baruscotti M, DiFrancesco D, Lakatta EG, Watkins H, Ashrafian H.

Nat Commun. 2017 Nov 2;8(1):1258. doi: 10.1038/s41467-017-01342-5.

5.

Families' experiences of raising concerns in health care services: An interpretative phenomenological analysis.

Bright N, Hutchinson N, Oakes P, Marsland D.

J Appl Res Intellect Disabil. 2018 May;31(3):405-412. doi: 10.1111/jar.12419. Epub 2017 Oct 10.

PMID:
28994488
6.

Relationship of low doses of alcohol voluntarily consumed during adolescence and early adulthood with subsequent behavioral flexibility.

Fisher H, Bright N, Gallo M, Pajser A, Pickens CL.

Behav Pharmacol. 2017 Oct;28(7):531-544. doi: 10.1097/FBP.0000000000000331.

PMID:
28906303
7.

Development and clinical performance of high throughput loop-mediated isothermal amplification for detection of malaria.

Perera RS, Ding XC, Tully F, Oliver J, Bright N, Bell D, Chiodini PL, Gonzalez IJ, Polley SD.

PLoS One. 2017 Feb 6;12(2):e0171126. doi: 10.1371/journal.pone.0171126. eCollection 2017.

8.

Exosomes bind to autotaxin and act as a physiological delivery mechanism to stimulate LPA receptor signalling in cells.

Jethwa SA, Leah EJ, Zhang Q, Bright NA, Oxley D, Bootman MD, Rudge SA, Wakelam MJ.

J Cell Sci. 2016 Oct 15;129(20):3948-3957. Epub 2016 Aug 24.

9.

Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity.

Bright NA, Davis LJ, Luzio JP.

Curr Biol. 2016 Sep 12;26(17):2233-45. doi: 10.1016/j.cub.2016.06.046. Epub 2016 Aug 4.

10.
11.

Prior alcohol consumption does not impair go/no-go discrimination learning, but causes over-responding on go trials, in rats.

Pickens CL, Fisher H, Bright N, Gallo M, Ray MH, Anji A, Kumari M.

Behav Brain Res. 2016 Oct 1;312:272-8. doi: 10.1016/j.bbr.2016.06.028. Epub 2016 Jun 17.

PMID:
27327103
12.

A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I.

Parkinson MD, Piper SC, Bright NA, Evans JL, Boname JM, Bowers K, Lehner PJ, Luzio JP.

Biochem J. 2015 Oct 1;471(1):79-88. doi: 10.1042/BJ20150336. Epub 2015 Jul 28.

13.

CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.

Miller SE, Mathiasen S, Bright NA, Pierre F, Kelly BT, Kladt N, Schauss A, Merrifield CJ, Stamou D, Höning S, Owen DJ.

Dev Cell. 2015 Apr 20;33(2):163-75. doi: 10.1016/j.devcel.2015.03.002.

14.

Lysosomes.

Wartosch L, Bright NA, Luzio JP.

Curr Biol. 2015 Apr 20;25(8):R315-6. doi: 10.1016/j.cub.2015.02.027. No abstract available.

15.

Lysosome fusion in cultured mammalian cells.

Bright NA, Wartosch L, Luzio JP.

Methods Cell Biol. 2015;126:101-18. doi: 10.1016/bs.mcb.2014.10.029. Epub 2015 Jan 14.

PMID:
25665443
16.

Repetition Suppression in Ventral Visual Cortex Is Diminished as a Function of Increasing Autistic Traits.

Ewbank MP, Rhodes G, von dem Hagen EA, Powell TE, Bright N, Stoyanova RS, Baron-Cohen S, Calder AJ.

Cereb Cortex. 2015 Oct;25(10):3381-93. doi: 10.1093/cercor/bhu149. Epub 2014 Jul 1.

17.

Structural basis of AMPK regulation by small molecule activators.

Xiao B, Sanders MJ, Carmena D, Bright NJ, Haire LF, Underwood E, Patel BR, Heath RB, Walker PA, Hallen S, Giordanetto F, Martin SR, Carling D, Gamblin SJ.

Nat Commun. 2013;4:3017. doi: 10.1038/ncomms4017.

18.

Enhanced imaging of developed fingerprints using mass spectrometry imaging.

Bailey MJ, Ismail M, Bleay S, Bright N, Levin Elad M, Cohen Y, Geller B, Everson D, Costa C, Webb RP, Watts JF, de Puit M.

Analyst. 2013 Nov 7;138(21):6246-50. doi: 10.1039/c3an01204b.

PMID:
23991428
19.

Type VII collagen associated with the basement membrane of amniotic epithelium forms giant anchoring rivets which penetrate a massive lamina reticularis.

Ockleford CD, McCracken SA, Rimmington LA, Hubbard AR, Bright NA, Cockcroft N, Jefferson TB, Waldron E, d'Lacey C.

Placenta. 2013 Sep;34(9):727-37. doi: 10.1016/j.placenta.2013.06.002. Epub 2013 Jul 5.

PMID:
23834951
20.

Chemical changes exhibited by latent fingerprints after exposure to vacuum conditions.

Bright NJ, Willson TR, Driscoll DJ, Reddy SM, Webb RP, Bleay S, Ward NI, Kirkby KJ, Bailey MJ.

Forensic Sci Int. 2013 Jul 10;230(1-3):81-6. doi: 10.1016/j.forsciint.2013.03.047. Epub 2013 Apr 23.

PMID:
23622791
21.

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation.

Schäfer IB, Hesketh GG, Bright NA, Gray SR, Pryor PR, Evans PR, Luzio JP, Owen DJ.

Nat Struct Mol Biol. 2012 Dec;19(12):1300-9. doi: 10.1038/nsmb.2414. Epub 2012 Oct 28.

22.

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome.

Tumbarello DA, Waxse BJ, Arden SD, Bright NA, Kendrick-Jones J, Buss F.

Nat Cell Biol. 2012 Oct;14(10):1024-35. doi: 10.1038/ncb2589. Epub 2012 Sep 30.

23.
24.

Determination of the deposition order of overlapping latent fingerprints and inks using secondary ion mass spectrometry.

Bright NJ, Webb RP, Bleay S, Hinder S, Ward NI, Watts JF, Kirkby KJ, Bailey MJ.

Anal Chem. 2012 May 1;84(9):4083-7. doi: 10.1021/ac300185j. Epub 2012 Apr 16.

PMID:
22462501
25.

The autoimmunity-related GIMAP5 GTPase is a lysosome-associated protein.

Wong VW, Saunders AE, Hutchings A, Pascall JC, Carter C, Bright NA, Walker SA, Ktistakis NT, Butcher GW.

Self Nonself. 2010 Jul;1(3):259-268. Epub 2010 Jun 25.

26.

AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure.

Thornton C, Bright NJ, Sastre M, Muckett PJ, Carling D.

Biochem J. 2011 Mar 15;434(3):503-12. doi: 10.1042/BJ20101485.

PMID:
21204788
27.

Endosome-lysosome fusion.

Luzio JP, Gray SR, Bright NA.

Biochem Soc Trans. 2010 Dec;38(6):1413-6. doi: 10.1042/BST0381413.

PMID:
21118098
28.

Educational outreach to reduce immunization pain in office settings.

Schechter NL, Bernstein BA, Zempsky WT, Bright NS, Willard AK.

Pediatrics. 2010 Dec;126(6):e1514-21. doi: 10.1542/peds.2010-1597. Epub 2010 Nov 15.

PMID:
21078736
29.

The sodium/proton exchanger NHE8 regulates late endosomal morphology and function.

Lawrence SP, Bright NA, Luzio JP, Bowers K.

Mol Biol Cell. 2010 Oct 15;21(20):3540-51. doi: 10.1091/mbc.E09-12-1053. Epub 2010 Aug 18.

30.

Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C.

Roberts RC, Peden AA, Buss F, Bright NA, Latouche M, Reilly MM, Kendrick-Jones J, Luzio JP.

Hum Mol Genet. 2010 Mar 15;19(6):1009-18. doi: 10.1093/hmg/ddp565. Epub 2009 Dec 22.

31.

The delivery of endocytosed cargo to lysosomes.

Luzio JP, Parkinson MD, Gray SR, Bright NA.

Biochem Soc Trans. 2009 Oct;37(Pt 5):1019-21. doi: 10.1042/BST0371019. Review.

PMID:
19754443
32.

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5.

Seaman MN, Harbour ME, Tattersall D, Read E, Bright N.

J Cell Sci. 2009 Jul 15;122(Pt 14):2371-82. doi: 10.1242/jcs.048686. Epub 2009 Jun 16.

33.

SDPR induces membrane curvature and functions in the formation of caveolae.

Hansen CG, Bright NA, Howard G, Nichols BJ.

Nat Cell Biol. 2009 Jul;11(7):807-14. doi: 10.1038/ncb1887. Epub 2009 Jun 14.

34.

The regulation and function of mammalian AMPK-related kinases.

Bright NJ, Thornton C, Carling D.

Acta Physiol (Oxf). 2009 May;196(1):15-26. doi: 10.1111/j.1748-1716.2009.01971.x. Epub 2009 Feb 19. Review.

PMID:
19245655
35.

Sequence analysis of Escherichia coli O157:H7 bacteriophage PhiV10 and identification of a phage-encoded immunity protein that modifies the O157 antigen.

Perry LL, SanMiguel P, Minocha U, Terekhov AI, Shroyer ML, Farris LA, Bright N, Reuhs BL, Applegate BM.

FEMS Microbiol Lett. 2009 Mar;292(2):182-6. doi: 10.1111/j.1574-6968.2009.01511.x. Epub 2009 Feb 5.

36.

ESCRT proteins and the regulation of endocytic delivery to lysosomes.

Luzio JP, Piper SC, Bowers K, Parkinson MD, Lehner PJ, Bright NA.

Biochem Soc Trans. 2009 Feb;37(Pt 1):178-80. doi: 10.1042/BST0370178.

PMID:
19143626
37.

Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate.

Louagie E, Taylor NA, Flamez D, Roebroek AJ, Bright NA, Meulemans S, Quintens R, Herrera PL, Schuit F, Van de Ven WJ, Creemers JW.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12319-24. doi: 10.1073/pnas.0800340105. Epub 2008 Aug 19.

38.

Patients' perspectives on total knee replacement.

Jacobson AF, Myerscough RP, Delambo K, Fleming E, Huddleston AM, Bright N, Varley JD.

Am J Nurs. 2008 May;108(5):54-63; quiz 63-4. doi: 10.1097/01.NAJ.0000318000.62786.fb.

PMID:
18434802
39.

Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation.

Bright NJ, Carling D, Thornton C.

J Biol Chem. 2008 May 30;283(22):14946-54. doi: 10.1074/jbc.M710381200. Epub 2008 Mar 13.

40.

Clathrin light chains function in mannose phosphate receptor trafficking via regulation of actin assembly.

Poupon V, Girard M, Legendre-Guillemin V, Thomas S, Bourbonniere L, Philie J, Bright NA, McPherson PS.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):168-73. doi: 10.1073/pnas.0707269105. Epub 2007 Dec 28.

41.

The role of calcium and other ions in sorting and delivery in the late endocytic pathway.

Luzio JP, Bright NA, Pryor PR.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1088-91. Review.

PMID:
17956286
42.

Lysosomes: fusion and function.

Luzio JP, Pryor PR, Bright NA.

Nat Rev Mol Cell Biol. 2007 Aug;8(8):622-32. Review.

PMID:
17637737
43.

Coassembly of flotillins induces formation of membrane microdomains, membrane curvature, and vesicle budding.

Frick M, Bright NA, Riento K, Bray A, Merrified C, Nichols BJ.

Curr Biol. 2007 Jul 3;17(13):1151-6.

44.

Pain reduction during pediatric immunizations: evidence-based review and recommendations.

Schechter NL, Zempsky WT, Cohen LL, McGrath PJ, McMurtry CM, Bright NS.

Pediatrics. 2007 May;119(5):e1184-98. Review.

PMID:
17473085
45.

ATP regulation in adult rat cardiomyocytes: time-resolved decoding of rapid mitochondrial calcium spiking imaged with targeted photoproteins.

Bell CJ, Bright NA, Rutter GA, Griffiths EJ.

J Biol Chem. 2006 Sep 22;281(38):28058-67. Epub 2006 Jul 31.

46.

Metachronous metastasis to the penis from carcinoma of the rectum.

Appu S, Lawrentschuk N, Russell JM, Bright NF.

Int J Urol. 2006 May;13(5):659-61.

47.

Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells.

Glebov OO, Bright NA, Nichols BJ.

Nat Cell Biol. 2006 Jan;8(1):46-54. Epub 2005 Dec 11.

PMID:
16341206
48.

Spastin and atlastin, two proteins mutated in autosomal-dominant hereditary spastic paraplegia, are binding partners.

Sanderson CM, Connell JW, Edwards TL, Bright NA, Duley S, Thompson A, Luzio JP, Reid E.

Hum Mol Genet. 2006 Jan 15;15(2):307-18. Epub 2005 Dec 8.

49.

Molecular characterization of autoinduction of bioluminescence in the Microtox indicator strain Vibrio fischeri ATCC 49387.

Perry LL, Bright NG, Carroll RJ Jr, Scott MC, Allen MS, Applegate BM.

Can J Microbiol. 2005 Jul;51(7):549-57.

PMID:
16175203
50.

Clathrin is required for the function of the mitotic spindle.

Royle SJ, Bright NA, Lagnado L.

Nature. 2005 Apr 28;434(7037):1152-7.

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