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Items: 10


An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration.

Tajadura-Ortega V, Garg R, Allen R, Owczarek C, Bright MD, Kean S, Mohd-Noor A, Grigoriadis A, Elston TC, Hahn KM, Ridley AJ.

BMC Biol. 2018 Mar 6;16(1):29. doi: 10.1186/s12915-018-0489-4.


HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.

Fok JHL, Hedayat S, Zhang L, Aronson LI, Mirabella F, Pawlyn C, Bright MD, Wardell CP, Keats JJ, De Billy E, Rye CS, Chessum NEA, Jones K, Morgan GJ, Eccles SA, Workman P, Davies FE.

Clin Cancer Res. 2018 May 15;24(10):2395-2407. doi: 10.1158/1078-0432.CCR-17-1594. Epub 2018 Feb 1.


Oncogenic RAC1 and NRAS drive resistance to endoplasmic reticulum stress through MEK/ERK signalling.

Bright MD, Clarke PA, Workman P, Davies FE.

Cell Signal. 2018 Apr;44:127-137. doi: 10.1016/j.cellsig.2018.01.004. Epub 2018 Jan 9.


Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control.

Pawlyn C, Bright MD, Buros AF, Stein CK, Walters Z, Aronson LI, Mirabella F, Jones JR, Kaiser MF, Walker BA, Jackson GH, Clarke PA, Bergsagel PL, Workman P, Chesi M, Morgan GJ, Davies FE.

Blood Cancer J. 2017 Mar 31;7(3):e549. doi: 10.1038/bcj.2017.27.


Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress.

Bright MD, Itzhak DN, Wardell CP, Morgan GJ, Davies FE.

Mol Cell Biol. 2015 Jun;35(12):2186-202. doi: 10.1128/MCB.00013-15. Epub 2015 Apr 13.


The motor protein myosin 1G functions in FcγR-mediated phagocytosis.

Dart AE, Tollis S, Bright MD, Frankel G, Endres RG.

J Cell Sci. 2012 Dec 15;125(Pt 24):6020-9. doi: 10.1242/jcs.109561. Epub 2012 Oct 4.


PAK4 phosphorylates myosin regulatory light chain and contributes to Fcγ receptor-mediated phagocytosis.

Bright MD, Frankel G.

Int J Biochem Cell Biol. 2011 Dec;43(12):1776-81. doi: 10.1016/j.biocel.2011.08.015. Epub 2011 Sep 3.


Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements.

Wong AR, Pearson JS, Bright MD, Munera D, Robinson KS, Lee SF, Frankel G, Hartland EL.

Mol Microbiol. 2011 Jun;80(6):1420-38. doi: 10.1111/j.1365-2958.2011.07661.x. Epub 2011 May 5. Review.


PAK1 and PAK2 have different roles in HGF-induced morphological responses.

Bright MD, Garner AP, Ridley AJ.

Cell Signal. 2009 Dec;21(12):1738-47. doi: 10.1016/j.cellsig.2009.07.005. Epub 2009 Jul 21.


Demonstration of competence and progression activities for human fibroblasts.

Bright MD, Gaffney EV.

Exp Cell Res. 1982 Feb;137(2):309-16. No abstract available.


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