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Items: 43

1.

Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.

André V, Gau C, Scheideler A, Aguilar-Pimentel JA, Amarie OV, Becker L, Garrett L, Hans W, Hölter SM, Janik D, Moreth K, Neff F, Östereicher M, Racz I, Rathkolb B, Rozman J, Bekeredjian R, Graw J, Klingenspor M, Klopstock T, Ollert M, Schmidt-Weber C, Wolf E, Wurst W, Gailus-Durner V, Brielmeier M, Fuchs H, Hrabé de Angelis M.

PLoS Biol. 2018 Apr 16;16(4):e2005019. doi: 10.1371/journal.pbio.2005019. eCollection 2018 Apr.

2.

Environmental samples make soiled bedding sentinels dispensable for hygienic monitoring of IVC-reared mouse colonies.

Miller M, Brielmeier M.

Lab Anim. 2018 Jun;52(3):233-239. doi: 10.1177/0023677217739329. Epub 2017 Nov 16.

PMID:
29145766
3.

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Fuchs H, Aguilar-Pimentel JA, Amarie OV, Becker L, Calzada-Wack J, Cho YL, Garrett L, Hölter SM, Irmler M, Kistler M, Kraiger M, Mayer-Kuckuk P, Moreth K, Rathkolb B, Rozman J, da Silva Buttkus P, Treise I, Zimprich A, Gampe K, Hutterer C, Stöger C, Leuchtenberger S, Maier H, Miller M, Scheideler A, Wu M, Beckers J, Bekeredjian R, Brielmeier M, Busch DH, Klingenspor M, Klopstock T, Ollert M, Schmidt-Weber C, Stöger T, Wolf E, Wurst W, Yildirim AÖ, Zimmer A, Gailus-Durner V, Hrabě de Angelis M.

Behav Brain Res. 2018 Oct 15;352:187-196. doi: 10.1016/j.bbr.2017.09.048. Epub 2017 Sep 29. Review.

PMID:
28966146
4.
5.

Murine norovirus detection in the exhaust air of IVCs is more sensitive than serological analysis of soiled bedding sentinels.

Zorn J, Ritter B, Miller M, Kraus M, Northrup E, Brielmeier M.

Lab Anim. 2017 Jun;51(3):301-310. doi: 10.1177/0023677216661586. Epub 2016 Jul 20.

PMID:
27440411
6.

High-Resolution Melting Curve Analysis for Identification of Pasteurellaceae Species in Experimental Animal Facilities.

Miller M, Zorn J, Brielmeier M.

PLoS One. 2015 Nov 10;10(11):e0142560. doi: 10.1371/journal.pone.0142560. eCollection 2015.

7.

Heart-Specific Knockout of the Mitochondrial Thioredoxin Reductase (Txnrd2) Induces Metabolic and Contractile Dysfunction in the Aging Myocardium.

Kiermayer C, Northrup E, Schrewe A, Walch A, de Angelis MH, Schoensiegel F, Zischka H, Prehn C, Adamski J, Bekeredjian R, Ivandic B, Kupatt C, Brielmeier M.

J Am Heart Assoc. 2015 Jul 21;4(7). pii: e002153. doi: 10.1161/JAHA.115.002153.

8.

Influence of 5 different caging types and the use of cage-changing stations on mouse allergen exposure.

Feistenauer S, Sander I, Schmidt J, Zahradnik E, Raulf M, Brielmeier M.

J Am Assoc Lab Anim Sci. 2014 Jul;53(4):356-63.

9.

Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons.

Wirth EK, Bharathi BS, Hatfield D, Conrad M, Brielmeier M, Schweizer U.

Biol Trace Elem Res. 2014 May;158(2):203-10. doi: 10.1007/s12011-014-9920-z. Epub 2014 Mar 6.

10.

Muscle force development after low-frequency magnetic burst stimulation in dogs.

Emrich D, Fischer A, Altenhöfer C, Weyh T, Helling F, Goetz S, Brielmeier M, Matiasek K.

Muscle Nerve. 2012 Dec;46(6):954-6. doi: 10.1002/mus.23523.

PMID:
23225387
11.

Structural and functional concepts in current mouse phenotyping and archiving facilities.

Kollmus H, Post R, Brielmeier M, Fernández J, Fuchs H, McKerlie C, Montoliu L, Otaegui PJ, Rebelo M, Riedesel H, Ruberte J, Sedlacek R, de Angelis MH, Schughart K.

J Am Assoc Lab Anim Sci. 2012 Jul;51(4):418-35.

12.

Musculoskeletal load in and highly repetitive actions of animal facility washroom employees.

Kiermayer C, Hoehne-Hückstädt UM, Brielmeier M, Brütting M, Ellegast R, Schmidt J.

J Am Assoc Lab Anim Sci. 2011 Sep;50(5):665-74.

13.

Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection.

Horstkotte J, Perisic T, Schneider M, Lange P, Schroeder M, Kiermayer C, Hinkel R, Ziegler T, Mandal PK, David R, Schulz S, Schmitt S, Widder J, Sinowatz F, Becker BF, Bauersachs J, Naebauer M, Franz WM, Jeremias I, Brielmeier M, Zischka H, Conrad M, Kupatt C.

Circulation. 2011 Dec 20;124(25):2892-902. doi: 10.1161/CIRCULATIONAHA.111.059253. Epub 2011 Dec 5.

PMID:
22144571
14.

Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.

Aichler M, Seiler C, Tost M, Siveke J, Mazur PK, Da Silva-Buttkus P, Bartsch DK, Langer P, Chiblak S, Dürr A, Höfler H, Klöppel G, Müller-Decker K, Brielmeier M, Esposito I.

J Pathol. 2012 Apr;226(5):723-34. doi: 10.1002/path.3017. Epub 2012 Jan 17.

PMID:
21984419
15.

The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models.

Fuchs H, Gailus-Durner V, Adler T, Pimentel JA, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Dalke C, Ehrhardt N, Fasnacht N, Ferwagner B, Frischmann U, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Maier H, Mossbrugger I, Mörth C, Naton B, Nöth U, Pasche B, Prehn C, Przemeck G, Puk O, Racz I, Rathkolb B, Rozman J, Schäble K, Schreiner R, Schrewe A, Sina C, Steinkamp R, Thiele F, Willershäuser M, Zeh R, Adamski J, Busch DH, Beckers J, Behrendt H, Daniel H, Esposito I, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Klingenspor M, Klopstock T, Lengeling A, Mempel M, Müller W, Neschen S, Ollert M, Quintanilla-Martinez L, Rosenstiel P, Schmidt J, Schreiber S, Schughart K, Schulz H, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M.

Curr Pharm Biotechnol. 2009 Feb;10(2):236-43.

PMID:
19199957
16.

Evaluation of polymerase chain reaction methods for detection of murine Helicobacter in nine diagnostic laboratories.

Moerth C, Mahabir E, Brielmeier M, Markoullis K, Beisker W, Needham J, Balzer HJ, Bater LE, Bleich A, Deeny A, Dix J, Jacobsen K, Lorenz A, Mähler M, Nicklas W, Phipps JD, Seidel KE, Seidelin M, Toft MF, Tomlinson A, Wilhelm P, Schmidt J.

Lab Anim (NY). 2008 Nov;37(11):521-7. doi: 10.1038/laban1108-521. No abstract available.

PMID:
18948992
17.

The role of thioredoxin reductases in brain development.

Soerensen J, Jakupoglu C, Beck H, Förster H, Schmidt J, Schmahl W, Schweizer U, Conrad M, Brielmeier M.

PLoS One. 2008 Mar 19;3(3):e1813. doi: 10.1371/journal.pone.0001813.

18.

Effect of selenium on thioredoxin reductase activity in Txnrd1 or Txnrd2 hemizygous mice.

Kiermayer C, Michalke B, Schmidt J, Brielmeier M.

Biol Chem. 2007 Oct;388(10):1091-7.

PMID:
17937623
19.

B- and T-cell-specific inactivation of thioredoxin reductase 2 does not impair lymphocyte development and maintenance.

Geisberger R, Kiermayer C, Hömig C, Conrad M, Schmidt J, Zimber-Strobl U, Brielmeier M.

Biol Chem. 2007 Oct;388(10):1083-90.

PMID:
17937622
20.

Selenium status alters tumour differentiation but not incidence or latency of pancreatic adenocarcinomas in Ela-TGF-alpha p53+/ mice.

Aichler M, Algül H, Behne D, Hölzlwimmer G, Michalke B, Quintanilla-Martinez L, Schmidt J, Schmid RM, Brielmeier M.

Carcinogenesis. 2007 Sep;28(9):2002-7. Epub 2007 Jul 17.

PMID:
17638921
21.

Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate.

Kiermayer C, Conrad M, Schneider M, Schmidt J, Brielmeier M.

Genesis. 2007 Jan;45(1):11-6.

PMID:
17216603
22.

Microbiological monitoring of laboratory mice and biocontainment in individually ventilated cages: a field study.

Brielmeier M, Mahabir E, Needham JR, Lengger C, Wilhelm P, Schmidt J.

Lab Anim. 2006 Jul;40(3):247-60.

PMID:
16803642
23.

Embryonic expression profile of phospholipid hydroperoxide glutathione peroxidase.

Schneider M, Vogt Weisenhorn DM, Seiler A, Bornkamm GW, Brielmeier M, Conrad M.

Gene Expr Patterns. 2006 Jun;6(5):489-94. Epub 2006 Feb 2.

PMID:
16458079
24.

Monitoring a mouse colony for Helicobacter bilis using a Helicobacter-genus-specific nested PCR.

Jacobsen K, Mahabir E, Brielmeier M, Wilhelm P, Seidel KE, Schmidt J.

Lab Anim. 2005 Oct;39(4):400-12.

PMID:
16197707
25.

The nuclear form of phospholipid hydroperoxide glutathione peroxidase is a protein thiol peroxidase contributing to sperm chromatin stability.

Conrad M, Moreno SG, Sinowatz F, Ursini F, Kölle S, Roveri A, Brielmeier M, Wurst W, Maiorino M, Bornkamm GW.

Mol Cell Biol. 2005 Sep;25(17):7637-44.

26.

Introducing the German Mouse Clinic: open access platform for standardized phenotyping.

Gailus-Durner V, Fuchs H, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Elvert R, Ehrhardt N, Dalke C, Franz TJ, Grundner-Culemann E, Hammelbacher S, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kalaydjiev SV, Klempt M, Kling E, Kunder S, Lengger C, Lisse T, Mijalski T, Naton B, Pedersen V, Prehn C, Przemeck G, Racz I, Reinhard C, Reitmeir P, Schneider I, Schrewe A, Steinkamp R, Zybill C, Adamski J, Beckers J, Behrendt H, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Kirchhof P, Klingenspor M, Klopstock T, Lengeling A, Müller W, Ohl F, Ollert M, Quintanilla-Martinez L, Schmidt J, Schulz H, Wolf E, Wurst W, Zimmer A, Busch DH, de Angelis MH.

Nat Methods. 2005 Jun;2(6):403-4. No abstract available.

PMID:
15908916
27.

Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development.

Jakupoglu C, Przemeck GK, Schneider M, Moreno SG, Mayr N, Hatzopoulos AK, de Angelis MH, Wurst W, Bornkamm GW, Brielmeier M, Conrad M.

Mol Cell Biol. 2005 Mar;25(5):1980-8.

28.

Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function.

Conrad M, Jakupoglu C, Moreno SG, Lippl S, Banjac A, Schneider M, Beck H, Hatzopoulos AK, Just U, Sinowatz F, Schmahl W, Chien KR, Wurst W, Bornkamm GW, Brielmeier M.

Mol Cell Biol. 2004 Nov;24(21):9414-23.

29.

Mouse antibody production test: can we do without it?

Mahabir E, Jacobsen K, Brielmeier M, Peters D, Needham J, Schmidt J.

J Virol Methods. 2004 Sep 15;120(2):239-45. Review.

PMID:
15288967
30.

Optimized vector for conditional gene targeting in mouse embryonic stem cells.

Conrad M, Brielmeier M, Wurst W, Bornkamm GW.

Biotechniques. 2003 Jun;34(6):1136-8, 1140. No abstract available.

31.

Testis-specific expression of the nuclear form of phospholipid hydroperoxide glutathione peroxidase (PHGPx).

Moreno SG, Laux G, Brielmeier M, Bornkamm GW, Conrad M.

Biol Chem. 2003 Apr;384(4):635-43.

PMID:
12751792
32.

Cloning of phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an anti-apoptotic and growth promoting gene of Burkitt lymphoma cells.

Brielmeier M, Béchet JM, Suppmann S, Conrad M, Laux G, Bornkamm GW.

Biofactors. 2001;14(1-4):179-90.

PMID:
11568455
33.

Antagonistic effects of c-myc and Epstein-Barr virus latent genes on the phenotype of human B cells.

Pajic A, Staege MS, Dudziak D, Schuhmacher M, Spitkovsky D, Eissner G, Brielmeier M, Polack A, Bornkamm GW.

Int J Cancer. 2001 Sep;93(6):810-6.

34.

Identification of a specific sperm nuclei selenoenzyme necessary for protamine thiol cross-linking during sperm maturation.

Pfeifer H, Conrad M, Roethlein D, Kyriakopoulos A, Brielmeier M, Bornkamm GW, Behne D.

FASEB J. 2001 May;15(7):1236-8. No abstract available.

PMID:
11344099
35.

Cell cycle activation by c-myc in a burkitt lymphoma model cell line.

Pajic A, Spitkovsky D, Christoph B, Kempkes B, Schuhmacher M, Staege MS, Brielmeier M, Ellwart J, Kohlhuber F, Bornkamm GW, Polack A, Eick D.

Int J Cancer. 2000 Sep 15;87(6):787-93.

36.

Activated Notch1 modulates gene expression in B cells similarly to Epstein-Barr viral nuclear antigen 2.

Strobl LJ, Höfelmayr H, Marschall G, Brielmeier M, Bornkamm GW, Zimber-Strobl U.

J Virol. 2000 Feb;74(4):1727-35.

37.

Improving stable transfection efficiency: antioxidants dramatically improve the outgrowth of clones under dominant marker selection.

Brielmeier M, Béchet JM, Falk MH, Pawlita M, Polack A, Bornkamm GW.

Nucleic Acids Res. 1998 May 1;26(9):2082-5.

38.

Apoptosis in Burkitt lymphoma cells is prevented by promotion of cysteine uptake.

Falk MH, Meier T, Issels RD, Brielmeier M, Scheffer B, Bornkamm GW.

Int J Cancer. 1998 Feb 9;75(4):620-5.

39.

Both Epstein-Barr viral nuclear antigen 2 (EBNA2) and activated Notch1 transactivate genes by interacting with the cellular protein RBP-J kappa.

Strobl LJ, Höfelmayr H, Stein C, Marschall G, Brielmeier M, Laux G, Bornkamm GW, Zimber-Strobl U.

Immunobiology. 1997 Dec;198(1-3):299-306. Review.

PMID:
9442401
40.

Mosaicicm in bcr-abl protein expression in B cells in chronic myelogenous leukemia.

Weissinger EM, Thalmeier K, Dull T, Grammer C, Kempkes B, Brielmeier M, Schumm M, Kolb HJ.

Int J Cancer. 1996 Nov 27;68(5):577-82.

41.

The latent membrane protein 2 gene of Epstein-Barr virus is important for efficient B cell immortalization.

Brielmeier M, Mautner J, Laux G, Hammerschmidt W.

J Gen Virol. 1996 Nov;77 ( Pt 11):2807-18.

PMID:
8922475
42.

Characterization of IkappaB kinases. IkappaB-alpha is not phosphorylated by Raf-1 or protein kinase C isozymes, but is a casein kinase II substrate.

Janosch P, Schellerer M, Seitz T, Reim P, Eulitz M, Brielmeier M, Kölch W, Sedivy JM, Mischak H.

J Biol Chem. 1996 Jun 7;271(23):13868-74.

43.

c-myc expression is activated by the immunoglobulin kappa-enhancers from a distance of at least 30 kb but not by elements located within 50 kb of the unaltered c-myc locus in vivo.

Mautner J, Behrends U, Hörtnagel K, Brielmeier M, Hammerschmidt W, Strobl L, Bornkamm GW, Polack A.

Oncogene. 1996 Mar 21;12(6):1299-307.

PMID:
8649832

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