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Items: 1 to 50 of 79

1.

DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study.

Pickles JC, Fairchild AR, Stone TJ, Brownlee L, Merve A, Yasin SA, Avery A, Ahmed SW, Ogunbiyi O, Gonzalez Zapata J, Peary AF, Edwards M, Wilkhu L, Dryden C, Ladon D, Kristiansen M, Rowe C, Kurian KM, Nicoll JAR, Mitchell C, Bloom T, Hilton DA, Al-Sarraj S, Doey L, Johns PN, Bridges LR, Chakrabarty A, Ismail A, Rathi N, Syed K, Lammie GA, Limback-Stanic C, Smith C, Torgersen A, Rae F, Hill RM, Clifford SC, Grabovska Y, Williamson D, Clarke M, Jones C, Capper D, Sill M, von Deimling A, Pfister SM, Jones DTW, Hargrave D, Chalker J, Jacques TS.

Lancet Child Adolesc Health. 2019 Nov 27. pii: S2352-4642(19)30342-6. doi: 10.1016/S2352-4642(19)30342-6. [Epub ahead of print]

PMID:
31786093
2.

Cell Senescence and Cerebral Small Vessel Disease in the Brains of People Aged 80 Years and Older.

Norton EJ, Bridges LR, Kenyon LC, Esiri MM, Bennett DC, Hainsworth AH.

J Neuropathol Exp Neurol. 2019 Nov 1;78(11):1066-1072. doi: 10.1093/jnen/nlz088.

PMID:
31553444
3.

Foix-Chavany-Marie syndrome due to type E TDP43 pathology.

Clark CN, Quaegebeur A, Nirmalananthan N, MacKinnon AD, Revesz T, Holton JL, Bridges LR, Pereira AC.

Neuropathol Appl Neurobiol. 2019 Sep 13. doi: 10.1111/nan.12579. [Epub ahead of print] No abstract available.

PMID:
31520433
4.

Epstein-Barr virus associated CNS lymphoproliferative disorder after long-term immunosuppression.

Lee A, Bridges LR, Lloyd M, Barker R, Wren DR, Galtrey CM.

Pract Neurol. 2019 Aug 29. pii: practneurol-2019-002356. doi: 10.1136/practneurol-2019-002356. [Epub ahead of print]

PMID:
31467148
5.

Rapid neuroinflammatory changes in human acute intracerebral hemorrhage.

Shtaya A, Bridges LR, Esiri MM, Lam-Wong J, Nicoll JAR, Boche D, Hainsworth AH.

Ann Clin Transl Neurol. 2019 Aug;6(8):1465-1479. doi: 10.1002/acn3.50842. Epub 2019 Jul 13.

6.

On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships.

McAleer CW, Pointon A, Long CJ, Brighton RL, Wilkin BD, Bridges LR, Narasimhan Sriram N, Fabre K, McDougall R, Muse VP, Mettetal JT, Srivastava A, Williams D, Schnepper MT, Roles JL, Shuler ML, Hickman JJ, Ewart L.

Sci Rep. 2019 Jul 3;9(1):9619. doi: 10.1038/s41598-019-45656-4.

7.

Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics.

McAleer CW, Long CJ, Elbrecht D, Sasserath T, Bridges LR, Rumsey JW, Martin C, Schnepper M, Wang Y, Schuler F, Roth AB, Funk C, Shuler ML, Hickman JJ.

Sci Transl Med. 2019 Jun 19;11(497). pii: eaav1386. doi: 10.1126/scitranslmed.aav1386.

PMID:
31217335
8.

The cGMP-Degrading Enzyme Phosphodiesterase-5 (PDE5) in Cerebral Small Arteries of Older People.

Vasita E, Yasmeen S, Andoh J, Bridges LR, Kruuse C, Pauls MMH, Pereira AC, Hainsworth AH.

J Neuropathol Exp Neurol. 2019 Feb 1;78(2):191-194. doi: 10.1093/jnen/nly117.

PMID:
30590671
9.

Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage.

Boltze J, Ferrara F, Hainsworth AH, Bridges LR, Zille M, Lobsien D, Barthel H, McLeod DD, Gräßer F, Pietsch S, Schatzl AK, Dreyer AY, Nitzsche B.

J Cereb Blood Flow Metab. 2019 Dec;39(12):2521-2535. doi: 10.1177/0271678X18802119. Epub 2018 Sep 21.

PMID:
30239258
10.

Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system.

Oleaga C, Riu A, Rothemund S, Lavado A, McAleer CW, Long CJ, Persaud K, Narasimhan NS, Tran M, Roles J, Carmona-Moran CA, Sasserath T, Elbrecht DH, Kumanchik L, Bridges LR, Martin C, Schnepper MT, Ekman G, Jackson M, Wang YI, Note R, Langer J, Teissier S, Hickman JJ.

Biomaterials. 2018 Nov;182:176-190. doi: 10.1016/j.biomaterials.2018.07.062. Epub 2018 Aug 4.

11.

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

Vinci M, Burford A, Molinari V, Kessler K, Popov S, Clarke M, Taylor KR, Pemberton HN, Lord CJ, Gutteridge A, Forshew T, Carvalho D, Marshall LV, Qin EY, Ingram WJ, Moore AS, Ng HK, Trabelsi S, H'mida-Ben Brahim D, Entz-Werle N, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Sunol M, Mora J, de Torres C, Cruz O, Carcaboso AM, Monje M, Mackay A, Jones C.

Nat Med. 2018 Aug;24(8):1204-1215. doi: 10.1038/s41591-018-0086-7. Epub 2018 Jul 2.

12.

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.

Mackay A, Burford A, Carvalho D, Izquierdo E, Fazal-Salom J, Taylor KR, Bjerke L, Clarke M, Vinci M, Nandhabalan M, Temelso S, Popov S, Molinari V, Raman P, Waanders AJ, Han HJ, Gupta S, Marshall L, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Ng HK, Li X, Mu K, Trabelsi S, Brahim DH, Kisljakov AN, Konovalov DM, Moore AS, Carcaboso AM, Sunol M, de Torres C, Cruz O, Mora J, Shats LI, Stavale JN, Bidinotto LT, Reis RM, Entz-Werle N, Farrell M, Cryan J, Crimmins D, Caird J, Pears J, Monje M, Debily MA, Castel D, Grill J, Hawkins C, Nikbakht H, Jabado N, Baker SJ, Pfister SM, Jones DTW, Fouladi M, von Bueren AO, Baudis M, Resnick A, Jones C.

Cancer Cell. 2017 Oct 9;32(4):520-537.e5. doi: 10.1016/j.ccell.2017.08.017. Epub 2017 Sep 28.

13.

Neuropathology of White Matter Lesions, Blood-Brain Barrier Dysfunction, and Dementia.

Hainsworth AH, Minett T, Andoh J, Forster G, Bhide I, Barrick TR, Elderfield K, Jeevahan J, Markus HS, Bridges LR.

Stroke. 2017 Oct;48(10):2799-2804. doi: 10.1161/STROKEAHA.117.018101. Epub 2017 Aug 30.

14.

Metastasising pleomorphic adenoma of the submandibular salivary gland presenting with spinal cord compression: case report and review of cases with CNS involvement.

Knight J, Bridges LR, Minhas PS, Eralil G.

Br J Neurosurg. 2017 Oct;31(5):611-613. doi: 10.1080/02688697.2016.1199781. Epub 2016 Jun 22.

PMID:
27333085
15.

Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma.

Carceller F, Fowkes LA, Khabra K, Moreno L, Saran F, Burford A, Mackay A, Jones DT, Hovestadt V, Marshall LV, Vaidya S, Mandeville H, Jerome N, Bridges LR, Laxton R, Al-Sarraj S, Pfister SM, Leach MO, Pearson AD, Jones C, Koh DM, Zacharoulis S.

J Neurooncol. 2016 Aug;129(1):109-21. doi: 10.1007/s11060-016-2151-8. Epub 2016 May 14.

PMID:
27180091
16.

Age-dependent expression of VEGFR2 in deep brain arteries in small vessel disease, CADASIL, and healthy brains.

Ahmed-Jushuf F, Jiwa NS, Arwani AS, Foot P, Bridges LR, Kalaria RN, Esiri MM, Hainsworth AH.

Neurobiol Aging. 2016 Jun;42:110-5. doi: 10.1016/j.neurobiolaging.2016.03.002. Epub 2016 Mar 10.

PMID:
27143427
17.

Whole exome sequence analysis reveals a homozygous mutation in PNPLA2 as the cause of severe dilated cardiomyopathy secondary to neutral lipid storage disease.

Muggenthaler M, Petropoulou E, Omer S, Simpson MA, Sahak H, Rice A, Raju H, Conti FJ, Bridges LR, Anderson LJ, Sharma S, Behr ER, Jamshidi Y.

Int J Cardiol. 2016 May 1;210:41-4. doi: 10.1016/j.ijcard.2016.02.082. Epub 2016 Feb 13. No abstract available.

PMID:
26922712
18.

Endothelial cells and human cerebral small vessel disease.

Hainsworth AH, Oommen AT, Bridges LR.

Brain Pathol. 2015 Jan;25(1):44-50. doi: 10.1111/bpa.12224. Review.

PMID:
25521176
19.

Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people.

Bridges LR, Andoh J, Lawrence AJ, Khoong CHL, Poon W, Esiri MM, Markus HS, Hainsworth AH.

J Neuropathol Exp Neurol. 2014 Nov;73(11):1026-1033. doi: 10.1097/NEN.0000000000000124.

20.

A giant cause of stroke.

Kong KK, Mackinnon AD, Bridges LR, Cloud GC.

Acute Med. 2014;13(2):68-71.

PMID:
24940569
21.

Isolated intracranial Rosai-Dorfman disease in a child, a case report and review of the literature.

Maratos EC, Bridges LR, MacKinnon AD, Madigan JB, Atra A, Martin AJ.

Childs Nerv Syst. 2014 Sep;30(9):1595-600. doi: 10.1007/s00381-014-2437-0. Epub 2014 May 27. Review.

PMID:
24864019
22.
23.

Anosmin-1 contributes to brain tumor malignancy through integrin signal pathways.

Choy CT, Kim H, Lee JY, Williams DM, Palethorpe D, Fellows G, Wright AJ, Laing K, Bridges LR, Howe FA, Kim SH.

Endocr Relat Cancer. 2013 Dec 20;21(1):85-99. doi: 10.1530/ERC-13-0181. Print 2014 Feb.

24.

Cerebral subcortical small vessel disease in subjects with pathologically confirmed Alzheimer disease: a clinicopathologic study in the Oxford Project to Investigate Memory and Ageing (OPTIMA).

Esiri MM, Joachim C, Sloan C, Christie S, Agacinski G, Bridges LR, Wilcock GK, Smith AD.

Alzheimer Dis Assoc Disord. 2014 Jan-Mar;28(1):30-5. doi: 10.1097/WAD.0b013e31829b72f1.

PMID:
23842286
25.

Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.

Kim SH, Kowalski ML, Carson RP, Bridges LR, Ess KC.

Dis Model Mech. 2013 Jul;6(4):925-33. doi: 10.1242/dmm.011494. Epub 2013 Mar 27.

26.

Quantitative evaluation of MRI and histological characteristics of the 5xFAD Alzheimer mouse brain.

Spencer NG, Bridges LR, Elderfield K, Amir K, Austen B, Howe FA.

Neuroimage. 2013 Aug 1;76:108-15. doi: 10.1016/j.neuroimage.2013.02.071. Epub 2013 Mar 15.

PMID:
23507393
27.

An MRI-histological study of white matter in stroke-free SHRSP.

Brittain JF, McCabe C, Khatun H, Kaushal N, Bridges LR, Holmes WM, Barrick TR, Graham D, Dominiczak AF, Mhairi Macrae I, Hainsworth AH.

J Cereb Blood Flow Metab. 2013 May;33(5):760-3. doi: 10.1038/jcbfm.2013.14. Epub 2013 Feb 13.

28.

Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.

Ray KC, Moss ME, Franklin JL, Weaver CJ, Higginbotham J, Song Y, Revetta FL, Blaine SA, Bridges LR, Guess KE, Coffey RJ, Crawford HC, Washington MK, Means AL.

Oncogene. 2014 Feb 13;33(7):823-31. doi: 10.1038/onc.2013.3. Epub 2013 Feb 4.

29.

Paucity of natural killer and cytotoxic T cells in human neuromyelitis optica lesions.

Saadoun S, Bridges LR, Verkman AS, Papadopoulos MC.

Neuroreport. 2012 Dec 19;23(18):1044-7. doi: 10.1097/WNR.0b013e32835ab480.

30.

Devastating aquaporin-4 and HTLV-1-associated necrotizing encephalopathy.

Symmonds M, Nirmalananthan N, Taylor GP, Bridges LR, Schon F.

J Neurol. 2012 Dec;259(12):2732-5. doi: 10.1007/s00415-012-6651-y. Epub 2012 Aug 24. No abstract available.

PMID:
22918454
31.

Glioblastoma blood flow measured with stable xenon CT indicates tumor necrosis, vascularity, and brain invasion.

Crocker M, Saadoun S, Jury A, Jones C, Zacharoulis S, Thomas S, Zwiggelaar R, Bridges LR, Bell BA, Papadopoulos MC.

Neuro Oncol. 2012 May;14(5):641-8. doi: 10.1093/neuonc/nos063. Epub 2012 Apr 5.

32.

Paciniolipoma in congenital spinal dysraphism.

Hettige S, Smart C, Bridges LR, Martin AJ.

J Neurosurg Pediatr. 2012 Mar;9(3):280-2. doi: 10.3171/2011.12.PEDS11104.

PMID:
22380956
33.

Neuropathologic evidence of endothelial changes in cerebral small vessel disease.

Giwa MO, Williams J, Elderfield K, Jiwa NS, Bridges LR, Kalaria RN, Markus HS, Esiri MM, Hainsworth AH.

Neurology. 2012 Jan 17;78(3):167-74. doi: 10.1212/WNL.0b013e3182407968. Epub 2011 Dec 14.

PMID:
22170884
34.

Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation.

Viana-Pereira M, Lee A, Popov S, Bax DA, Al-Sarraj S, Bridges LR, Stávale JN, Hargrave D, Jones C, Reis RM.

PLoS One. 2011;6(5):e20588. doi: 10.1371/journal.pone.0020588. Epub 2011 May 26.

35.

T cell deficiency does not reduce lesions in mice produced by intracerebral injection of NMO-IgG and complement.

Saadoun S, Waters P, Macdonald C, Bridges LR, Bell BA, Vincent A, Verkman AS, Papadopoulos MC.

J Neuroimmunol. 2011 Jun;235(1-2):27-32. doi: 10.1016/j.jneuroim.2011.03.007. Epub 2011 Apr 13.

PMID:
21492943
36.

Clinical, histological and genetic characterization of reducing body myopathy caused by mutations in FHL1.

Schessl J, Taratuto AL, Sewry C, Battini R, Chin SS, Maiti B, Dubrovsky AL, Erro MG, Espada G, Robertella M, Saccoliti M, Olmos P, Bridges LR, Standring P, Hu Y, Zou Y, Swoboda KJ, Scavina M, Goebel HH, Mitchell CA, Flanigan KM, Muntoni F, Bönnemann CG.

Brain. 2009 Feb;132(Pt 2):452-64. doi: 10.1093/brain/awn325. Epub 2009 Jan 29.

37.

Vision loss due to coincident ocular and central causes in a patient with Heidenhain variant Creutzfeldt-Jakob disease.

Foundas M, Donaldson MD, McAllister IL, Bridges LR.

Age Ageing. 2008 Mar;37(2):231-2. Epub 2007 Dec 8.

PMID:
18065777
38.

40 year-old male with history of brain tumor 10 years ago.

Baborie A, Chakrabarty A, Kuruvath S, Roberts P, Timothy J, Bonsor G, van Hille P, Bridges LR.

Brain Pathol. 2007 Jul;17(3):337-9. No abstract available. Erratum in: Brain Pathol. 2008 Oct;18(4):640. Roberts, Paul [added].

PMID:
17598832
39.

Laing early onset distal myopathy: slow myosin defect with variable abnormalities on muscle biopsy.

Lamont PJ, Udd B, Mastaglia FL, de Visser M, Hedera P, Voit T, Bridges LR, Fabian V, Rozemuller A, Laing NG.

J Neurol Neurosurg Psychiatry. 2006 Feb;77(2):208-15. Epub 2005 Aug 15.

40.

Angioleiomyoma of the internal auditory meatus: a rare occurrence in the internal auditory canal.

Karagama YG, Bridges LR, van Hille PT.

Ear Nose Throat J. 2005 Apr;84(4):216, 218.

PMID:
15929320
41.

Epidemiology of central nervous system tumors in children and young adults (0-29 years), Yorkshire, United Kingdom.

Feltbower RG, Picton S, Bridges LR, Crooks DA, Glaser AW, McKinney PA.

Pediatr Hematol Oncol. 2004 Oct-Nov;21(7):647-60.

PMID:
15626021
42.

Progressive myoclonus epilepsy with polyglucosans (Lafora disease): evidence for a third locus.

Chan EM, Omer S, Ahmed M, Bridges LR, Bennett C, Scherer SW, Minassian BA.

Neurology. 2004 Aug 10;63(3):565-7.

PMID:
15304597
43.

Comparison of autologous serum eye drops with conventional therapy in a randomised controlled crossover trial for ocular surface disease.

Noble BA, Loh RS, MacLennan S, Pesudovs K, Reynolds A, Bridges LR, Burr J, Stewart O, Quereshi S.

Br J Ophthalmol. 2004 May;88(5):647-52.

44.

Hashimoto's encephalopathy: postmortem findings after fatal status epilepticus.

Duffey P, Yee S, Reid IN, Bridges LR.

Neurology. 2003 Oct 28;61(8):1124-6.

PMID:
14581677
45.

Genetic, ophthalmic, morphometric and histopathological analysis of the Retinopathy Globe Enlarged (rge) chicken.

Inglehearn CF, Morrice DR, Lester DH, Robertson GW, Mohamed MD, Simmons I, Downey LM, Thaung C, Bridges LR, Paton IR, Smith J, Petersen-Jones S, Hocking PM, Burt DW.

Mol Vis. 2003 Jul 1;9:295-300.

46.

Analysis of the rdd locus in chicken: a model for human retinitis pigmentosa.

Burt DW, Morrice DR, Lester DH, Robertson GW, Mohamed MD, Simmons I, Downey LM, Thaung C, Bridges LR, Paton IR, Gentle M, Smith J, Hocking PM, Inglehearn CF.

Mol Vis. 2003 Apr 30;9:164-70.

47.

Neuromuscular hamartoma of the cochlear nerve: a rare occurrence in the internal auditory meatus.

Karagama YG, Bridges LR, van Hille PT.

Eur Arch Otorhinolaryngol. 2002 Mar;259(3):119-20. Review.

PMID:
12003263
49.

Primary diffuse leptomeningeal gliomatosis predominantly affecting the spinal cord: case report and review of the literature.

Baborie A, Dunn EM, Bridges LR, Bamford JM.

J Neurol Neurosurg Psychiatry. 2001 Feb;70(2):256-8.

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