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Items: 1 to 50 of 179

1.

Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways.

Clements CS, Bikkul MU, Ofosu W, Eskiw C, Tree D, Makarov E, Kill IR, Bridger JM.

Biogerontology. 2019 Jun;20(3):337-358. doi: 10.1007/s10522-019-09807-4. Epub 2019 Apr 30.

2.

Deletions of Chromosome 7q Affect Nuclear Organization and HLXB9Gene Expression in Hematological Disorders.

Federico C, Owoka T, Ragusa D, Sturiale V, Caponnetto D, Leotta CG, Bruno F, Foster HA, Rigamonti S, Giudici G, Cazzaniga G, Bridger JM, Sisu C, Saccone S, Tosi S.

Cancers (Basel). 2019 Apr 25;11(4). pii: E585. doi: 10.3390/cancers11040585.

3.

The Genomic Health of Human Pluripotent Stem Cells: Genomic Instability and the Consequences on Nuclear Organization.

Henry MP, Hawkins JR, Boyle J, Bridger JM.

Front Genet. 2019 Jan 21;9:623. doi: 10.3389/fgene.2018.00623. eCollection 2018. Review.

4.

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform.

Bikkul MU, Faragher RGA, Worthington G, Meinke P, Kerr ARW, Sammy A, Riyahi K, Horton D, Schirmer EC, Hubank M, Kill IR, Anderson RM, Slijepcevic P, Makarov E, Bridger JM.

Genes Chromosomes Cancer. 2019 Jun;58(6):341-356. doi: 10.1002/gcc.22711. Epub 2019 Jan 7.

PMID:
30474255
5.

The snail Biomphalaria glabrata as a model to interrogate the molecular basis of complex human diseases.

Bridger JM, Brindley PJ, Knight M.

PLoS Negl Trop Dis. 2018 Aug 9;12(8):e0006552. doi: 10.1371/journal.pntd.0006552. eCollection 2018 Aug. No abstract available.

6.

Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson-Gilford progeria syndrome fibroblasts.

Bikkul MU, Clements CS, Godwin LS, Goldberg MW, Kill IR, Bridger JM.

Biogerontology. 2018 Dec;19(6):579-602. doi: 10.1007/s10522-018-9758-4. Epub 2018 Jun 15.

7.

Floral guidance of learning a preference for symmetry by bumblebees.

Plowright CMS, Bridger JJM, Xu V, Herlehy RA, Collin CA.

Anim Cogn. 2017 Nov;20(6):1115-1127. doi: 10.1007/s10071-017-1128-0. Epub 2017 Aug 30.

PMID:
28856458
8.

Corrigendum: Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Adema CM, Hillier LW, Jones CS, Loker ES, Knight M, Minx P, Oliveira G, Raghavan N, Shedlock A, do Amaral LR, Arican-Goktas HD, Assis JG, Baba EH, Baron OL, Bayne CJ, Bickham-Wright U, Biggar KK, Blouin M, Bonning BC, Botka C, Bridger JM, Buckley KM, Buddenborg SK, Lima Caldeira R, Carleton J, Carvalho OS, Castillo MG, Chalmers IW, Christensens M, Clifton S, Cosseau C, Coustau C, Cripps RM, Cuesta-Astroz Y, Cummins SF, Di Stefano L, Dinguirard N, Duval D, Emrich S, Feschotte C, Feyereisen R, FitzGerald P, Fronick C, Fulton L, Galinier R, Gava SG, Geusz M, Geyer KK, Giraldo-Calderón GI, de Souza Gomes M, Gordy MA, Gourbal B, Grunau C, Hanington PC, Hoffmann KF, Hughes D, Humphries J, Jackson DJ, Jannotti-Passos LK, de Jesus Jeremias W, Jobling S, Kamel B, Kapusta A, Kaur S, Koene JM, Kohn AB, Lawson D, Lawton SP, Liang D, Limpanont Y, Liu S, Lockyer AE, Lovato TAL, Ludolf F, Magrini V, McManus DP, Medina M, Misra M, Mitta G, Mkoji GM, Montague MJ, Montelongo C, Moroz LL, Munoz-Torres MC, Niazi U, Noble LR, Oliveira FS, Pais FS, Papenfuss AT, Peace R, Pena JJ, Pila EA, Quelais T, Raney BJ, Rast JP, Rollinson D, Rosse IC, Rotgans B, Routledge EJ, Ryan KM, Scholte LLS, Storey KB, Swain M, Tennessen JA, Tomlinson C, Trujillo DL, Volpi EV, Walker AJ, Wang T, Wannaporn I, Warren WC, Wu XJ, Yoshino TP, Yusuf M, Zhang SM, Zhao M, Wilson RK.

Nat Commun. 2017 Aug 23;8:16153. doi: 10.1038/ncomms16153.

9.

Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Adema CM, Hillier LW, Jones CS, Loker ES, Knight M, Minx P, Oliveira G, Raghavan N, Shedlock A, do Amaral LR, Arican-Goktas HD, Assis JG, Baba EH, Baron OL, Bayne CJ, Bickham-Wright U, Biggar KK, Blouin M, Bonning BC, Botka C, Bridger JM, Buckley KM, Buddenborg SK, Lima Caldeira R, Carleton J, Carvalho OS, Castillo MG, Chalmers IW, Christensens M, Clifton S, Cosseau C, Coustau C, Cripps RM, Cuesta-Astroz Y, Cummins SF, di Stephano L, Dinguirard N, Duval D, Emrich S, Feschotte C, Feyereisen R, FitzGerald P, Fronick C, Fulton L, Galinier R, Gava SG, Geusz M, Geyer KK, Giraldo-Calderón GI, de Souza Gomes M, Gordy MA, Gourbal B, Grunau C, Hanington PC, Hoffmann KF, Hughes D, Humphries J, Jackson DJ, Jannotti-Passos LK, de Jesus Jeremias W, Jobling S, Kamel B, Kapusta A, Kaur S, Koene JM, Kohn AB, Lawson D, Lawton SP, Liang D, Limpanont Y, Liu S, Lockyer AE, Lovato TL, Ludolf F, Magrini V, McManus DP, Medina M, Misra M, Mitta G, Mkoji GM, Montague MJ, Montelongo C, Moroz LL, Munoz-Torres MC, Niazi U, Noble LR, Oliveira FS, Pais FS, Papenfuss AT, Peace R, Pena JJ, Pila EA, Quelais T, Raney BJ, Rast JP, Rollinson D, Rosse IC, Rotgans B, Routledge EJ, Ryan KM, Scholte LLS, Storey KB, Swain M, Tennessen JA, Tomlinson C, Trujillo DL, Volpi EV, Walker AJ, Wang T, Wannaporn I, Warren WC, Wu XJ, Yoshino TP, Yusuf M, Zhang SM, Zhao M, Wilson RK.

Nat Commun. 2017 May 16;8:15451. doi: 10.1038/ncomms15451. Erratum in: Nat Commun. 2017 Aug 23;8:16153.

10.

The Compatibility Between Biomphalaria glabrata Snails and Schistosoma mansoni: An Increasingly Complex Puzzle.

Mitta G, Gourbal B, Grunau C, Knight M, Bridger JM, Théron A.

Adv Parasitol. 2017;97:111-145. doi: 10.1016/bs.apar.2016.08.006. Epub 2016 Sep 15. Review.

PMID:
28325369
11.

Visualizing the Spatial Relationship of the Genome with the Nuclear Envelope Using Fluorescence In Situ Hybridization.

Clements CS, Bikkul U, Ahmed MH, Foster HA, Godwin LS, Bridger JM.

Methods Mol Biol. 2016;1411:387-406. doi: 10.1007/978-1-4939-3530-7_24.

PMID:
27147055
12.

A structured environment helps to regulate nuclear architecture in breast epithelial cells.

Bridger JM, Kill IR.

Cell Cycle. 2016 May 2;15(9):1178-9. doi: 10.1080/15384101.2016.1147114. Epub 2016 Apr 14. No abstract available.

13.

Epigenetic modulation, stress and plasticity in susceptibility of the snail host, Biomphalaria glabrata, to Schistosoma mansoni infection.

Knight M, Ittiprasert W, Arican-Goktas HD, Bridger JM.

Int J Parasitol. 2016 Jun;46(7):389-94. doi: 10.1016/j.ijpara.2016.03.003. Epub 2016 Apr 4. Review.

PMID:
27056272
14.

Rapamycin reduces fibroblast proliferation without causing quiescence and induces STAT5A/B-mediated cytokine production.

Gillespie ZE, MacKay K, Sander M, Trost B, Dawicki W, Wickramarathna A, Gordon J, Eramian M, Kill IR, Bridger JM, Kusalik A, Mitchell JA, Eskiw CH.

Nucleus. 2015;6(6):490-506. doi: 10.1080/19491034.2015.1128610.

15.

Continuing Education on Suicide Assessment and Crisis Intervention: What Can We Learn About the Needs of Mental Health Professionals in Community Practice?

Mirick R, McCauley J, Bridger J, Berkowitz L.

Community Ment Health J. 2016 Jul;52(5):501-10. doi: 10.1007/s10597-015-9884-2. Epub 2015 May 9.

PMID:
25956584
16.

Cytometric analysis, genetic manipulation and antibiotic selection of the snail embryonic cell line Bge from Biomphalaria glabrata, the intermediate host of Schistosoma mansoni.

Rinaldi G, Yan H, Nacif-Pimenta R, Matchimakul P, Bridger J, Mann VH, Smout MJ, Brindley PJ, Knight M.

Int J Parasitol. 2015 Jul;45(8):527-35. doi: 10.1016/j.ijpara.2015.02.012. Epub 2015 Apr 20.

17.

Differential spatial repositioning of activated genes in Biomphalaria glabrata snails infected with Schistosoma mansoni.

Arican-Goktas HD, Ittiprasert W, Bridger JM, Knight M.

PLoS Negl Trop Dis. 2014 Sep 11;8(9):e3013. doi: 10.1371/journal.pntd.0003013. eCollection 2014 Sep.

18.

Schistosomes and snails: a molecular encounter.

Knight M, Arican-Goktas HD, Ittiprasert W, Odoemelam EC, Miller AN, Bridger JM.

Front Genet. 2014 Jul 21;5:230. doi: 10.3389/fgene.2014.00230. eCollection 2014. Review.

19.

The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer.

Bridger JM, Arican-Gotkas HD, Foster HA, Godwin LS, Harvey A, Kill IR, Knight M, Mehta IS, Ahmed MH.

Adv Exp Med Biol. 2014;773:263-79. doi: 10.1007/978-1-4899-8032-8_12. Review. Erratum in: Adv Exp Med Biol. 2014;773:E1.

PMID:
24563352
20.

The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer.

Wazir U, Ahmed MH, Bridger JM, Harvey A, Jiang WG, Sharma AK, Mokbel K.

Cell Mol Biol Lett. 2013 Dec;18(4):595-611. doi: 10.2478/s11658-013-0109-9. Epub 2013 Nov 30.

21.

Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells.

Foster HA, Estrada-Girona G, Themis M, Garimberti E, Hill MA, Bridger JM, Anderson RM.

Mutat Res. 2013 Aug 30;756(1-2):66-77. doi: 10.1016/j.mrgentox.2013.06.003. Epub 2013 Jun 18.

22.
23.

Will all scientists working on snails and the diseases they transmit please stand up?

Adema CM, Bayne CJ, Bridger JM, Knight M, Loker ES, Yoshino TP, Zhang SM.

PLoS Negl Trop Dis. 2012;6(12):e1835. doi: 10.1371/journal.pntd.0001835. Epub 2012 Dec 27. No abstract available.

24.

Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues.

Foster HA, Griffin DK, Bridger JM.

BMC Cell Biol. 2012 Nov 15;13:30. doi: 10.1186/1471-2121-13-30.

25.

Chromobility: the rapid movement of chromosomes in interphase nuclei.

Bridger JM.

Biochem Soc Trans. 2011 Dec;39(6):1747-51. doi: 10.1042/BST20110696. Review.

PMID:
22103519
26.

Progeria Research Day at Brunel University.

Bridger JM, Eskiw CH, Makarov EM, Tree D, Kill IR.

Nucleus. 2011 Nov-Dec;2(6):517-22. doi: 10.4161/nucl.2.6.17605. Epub 2011 Nov 1. Review.

27.

Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells.

Mehta IS, Eskiw CH, Arican HD, Kill IR, Bridger JM.

Genome Biol. 2011 Aug 12;12(8):R74. doi: 10.1186/gb-2011-12-8-r74.

28.

Genomic imbalances are confined to non-proliferating cells in paediatric patients with acute myeloid leukaemia and a normal or incomplete karyotype.

Ballabio E, Regan R, Garimberti E, Harbott J, Bradtke J, Teigler-Schlegel A, Biondi A, Cazzaniga G, Giudici G, Wainscoat JS, Boultwood J, Bridger JM, Knight SJ, Tosi S.

PLoS One. 2011;6(6):e20607. doi: 10.1371/journal.pone.0020607. Epub 2011 Jun 9.

29.

Association of adipogenic genes with SC-35 domains during porcine adipogenesis.

Szczerbal I, Bridger JM.

Chromosome Res. 2010 Dec;18(8):887-95. doi: 10.1007/s10577-010-9176-1. Epub 2010 Dec 3.

PMID:
21127962
30.

Non-random organization of the Biomphalaria glabrata genome in interphase Bge cells and the spatial repositioning of activated genes in cells co-cultured with Schistosoma mansoni.

Knight M, Ittiprasert W, Odoemelam EC, Adema CM, Miller A, Raghavan N, Bridger JM.

Int J Parasitol. 2011 Jan;41(1):61-70. doi: 10.1016/j.ijpara.2010.07.015. Epub 2010 Sep 16.

31.

Fluorescence in situ hybridization on early porcine embryos.

Foster HA, Sturmey RG, Stokes PJ, Leese HJ, Bridger JM, Griffin DK.

Methods Mol Biol. 2010;659:427-36. doi: 10.1007/978-1-60761-789-1_33.

PMID:
20809332
32.

FISH on chromosomes derived from the snail model organism Biomphalaria glabrata.

Odoemelam EC, Raghavan N, Ittiprasert W, Miller A, Bridger JM, Knight M.

Methods Mol Biol. 2010;659:379-88. doi: 10.1007/978-1-60761-789-1_29.

PMID:
20809328
33.

Fluorescence in situ hybridization on DNA halo preparations and extended chromatin fibres.

Elcock LS, Bridger JM.

Methods Mol Biol. 2010;659:21-31. doi: 10.1007/978-1-60761-789-1_2.

PMID:
20809301
34.

Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes.

Stimpson KM, Song IY, Jauch A, Holtgreve-Grez H, Hayden KE, Bridger JM, Sullivan BA.

PLoS Genet. 2010 Aug 12;6(8). pii: e1001061. doi: 10.1371/journal.pgen.1001061.

35.

Human antibody responses to bovine (Newbury-2) norovirus (GIII.2) and association to histo-blood group antigens.

Vildevall M, Grahn A, Oliver SL, Bridger JC, Charpilienne A, Poncet D, Larson G, Svensson L.

J Med Virol. 2010 Jul;82(7):1241-6. doi: 10.1002/jmv.21776.

PMID:
20513091
36.

Progeria, the nucleolus and farnesyltransferase inhibitors.

Mehta IS, Bridger JM, Kill IR.

Biochem Soc Trans. 2010 Feb;38(Pt 1):287-91. doi: 10.1042/BST0380287.

PMID:
20074076
37.

Exploring the relationship between interphase gene positioning, transcriptional regulation and the nuclear matrix.

Elcock LS, Bridger JM.

Biochem Soc Trans. 2010 Feb;38(Pt 1):263-7. doi: 10.1042/BST0380263. Review.

PMID:
20074071
38.

Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts.

Mehta IS, Amira M, Harvey AJ, Bridger JM.

Genome Biol. 2010 Jan 13;11(1):R5. doi: 10.1186/gb-2010-11-1-r5.

39.

The surgical anatomy of the radial nerve and the triceps aponeurosis.

Chaudhry T, Noor S, Maher B, Bridger J.

Clin Anat. 2010 Mar;23(2):222-6. doi: 10.1002/ca.20903.

PMID:
20014401
40.

Neonatal health in calves--comprehensive solutions for complex enteric disorders.

Makoschey B, Klee W, Martella V, Bridger J, Smiths DG, Daugschies A, Millemann Y, Liebler-Tenorio E, Snodgrass D, Claerebout E, Bendali F, van de Ven J, Garcia A, Illek J, Kaske M, Cutler K, González-Martín JV, Carvalho LM, Crouch C, Thiry E.

Berl Munch Tierarztl Wochenschr. 2009 Sep-Oct;122(9-10):398-408. English, German. No abstract available.

PMID:
19863013
41.

The spatial repositioning of adipogenesis genes is correlated with their expression status in a porcine mesenchymal stem cell adipogenesis model system.

Szczerbal I, Foster HA, Bridger JM.

Chromosoma. 2009 Oct;118(5):647-63. doi: 10.1007/s00412-009-0225-5. Epub 2009 Jul 8.

PMID:
19585140
42.

Comparison of the efficacy of rotavirus VLP vaccines to a live homologous rotavirus vaccine in a pig model of rotavirus disease.

El-Attar L, Oliver SL, Mackie A, Charpilienne A, Poncet D, Cohen J, Bridger JC.

Vaccine. 2009 May 21;27(24):3201-8. doi: 10.1016/j.vaccine.2009.03.043. Epub 2009 Apr 7.

PMID:
19446192
43.

Heterogeneity in the capsid protein of bovine enteric caliciviruses belonging to a new genus.

D'Mello F, Jervis SM, Edwards PM, Oliver SL, Bridger JC.

Virology. 2009 Apr 25;387(1):109-16. doi: 10.1016/j.virol.2009.01.035. Epub 2009 Feb 28.

44.

Epidemiological study of bovine norovirus infection by RT-PCR and a VLP-based antibody ELISA.

Mauroy A, Scipioni A, Mathijs E, Saegerman C, Mast J, Bridger JC, Ziant D, Thys C, Thiry E.

Vet Microbiol. 2009 Jun 12;137(3-4):243-51. doi: 10.1016/j.vetmic.2009.01.031. Epub 2009 Jan 30.

PMID:
19232845
45.

Revised karyotyping and gene mapping of the Biomphalaria glabrata embryonic (Bge) cell line.

Odoemelam E, Raghavan N, Miller A, Bridger JM, Knight M.

Int J Parasitol. 2009 May;39(6):675-81. doi: 10.1016/j.ijpara.2008.11.011. Epub 2008 Dec 24.

46.

The use of oxygen uptake rate to monitor discovery of microbial and enzymatic biocatalysts.

Dumsday GJ, Ocal G, Bridger JS, Zachariou M.

Biotechnol Bioeng. 2009 Feb 15;102(3):673-83. doi: 10.1002/bit.22115.

PMID:
19090578
47.

Towards a Drosophila model of Hutchinson-Gilford progeria syndrome.

Beard GS, Bridger JM, Kill IR, Tree DR.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1389-92. doi: 10.1042/BST0361389.

PMID:
19021561
48.

Nuclear motors and nuclear structures containing A-type lamins and emerin: is there a functional link?

Mehta IS, Elcock LS, Amira M, Kill IR, Bridger JM.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1384-8. doi: 10.1042/BST0361384. Review.

PMID:
19021560
49.

Exploring the effects of a dysfunctional nuclear matrix.

Elcock LS, Bridger JM.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1378-83. doi: 10.1042/BST0361378. Review.

PMID:
19021559
50.

FISH glossary: an overview of the fluorescence in situ hybridization technique.

Volpi EV, Bridger JM.

Biotechniques. 2008 Oct;45(4):385-6, 388, 390 passim. doi: 10.2144/000112811. Review.

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