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Items: 8


Development and Evaluation of an 18F-Radiolabeled Monocyclam Derivative for Imaging CXCR4 Expression.

Brickute D, Braga M, Kaliszczak MA, Barnes C, Lau D, Carroll L, Stevens E, Trousil S, Alam IS, Nguyen QD, Aboagye EO.

Mol Pharm. 2019 May 6;16(5):2106-2117. doi: 10.1021/acs.molpharmaceut.9b00069. Epub 2019 Apr 3.


Depicting Changes in Tumor Biology in Response to Cetuximab Monotherapy or Combination Therapy by Apoptosis and Proliferation Imaging Using 18F-ICMT-11 and 18F-FLT PET.

Heinzmann K, Nguyen QD, Honess D, Smith DM, Stribbling S, Brickute D, Barnes C, Griffiths J, Aboagye E.

J Nucl Med. 2018 Oct;59(10):1558-1565. doi: 10.2967/jnumed.118.209304. Epub 2018 May 24.


The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth.

Trousil S, Kaliszczak M, Schug Z, Nguyen QD, Tomasi G, Favicchio R, Brickute D, Fortt R, Twyman FJ, Carroll L, Kalusa A, Navaratnam N, Adejumo T, Carling D, Gottlieb E, Aboagye EO.

Oncotarget. 2016 Jun 14;7(24):37103-37120. doi: 10.18632/oncotarget.9466.


Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection.

Witney TH, Pisaneschi F, Alam IS, Trousil S, Kaliszczak M, Twyman F, Brickute D, Nguyen QD, Schug Z, Gottlieb E, Aboagye EO.

J Nucl Med. 2014 Sep;55(9):1506-12. doi: 10.2967/jnumed.114.140343. Epub 2014 Jul 10. Erratum in: J Nucl Med. 2014 Nov;55(11):1914.


Biodistribution and radiation dosimetry of deuterium-substituted 18F-fluoromethyl-[1, 2-2H4]choline in healthy volunteers.

Challapalli A, Sharma R, Hallett WA, Kozlowski K, Carroll L, Brickute D, Twyman F, Al-Nahhas A, Aboagye EO.

J Nucl Med. 2014 Feb;55(2):256-63. doi: 10.2967/jnumed.113.129577.


Radiosynthesis of the D2/3 agonist [3-11C]-(+)-PHNO using [11C]iodomethane.

Francisco Garcia-Arguello S, Fortt R, Steel CJ, Brickute D, Glaser M, Turton DR, Robins EG, Arstad E, Luthra SK.

Appl Radiat Isot. 2013 Mar;73:79-83. doi: 10.1016/j.apradiso.2012.11.009. Epub 2012 Nov 23.


Evaluation of deuterated 18F- and 11C-labeled choline analogs for cancer detection by positron emission tomography.

Witney TH, Alam IS, Turton DR, Smith G, Carroll L, Brickute D, Twyman FJ, Nguyen QD, Tomasi G, Awais RO, Aboagye EO.

Clin Cancer Res. 2012 Feb 15;18(4):1063-72. doi: 10.1158/1078-0432.CCR-11-2462. Epub 2012 Jan 10.


Further evaluation of the carbon11-labeled D(2/3) agonist PET radiotracer PHNO: reproducibility in tracer characteristics and characterization of extrastriatal binding.

Egerton A, Hirani E, Ahmad R, Turton DR, Brickute D, Rosso L, Howes OD, Luthra SK, Grasby PM.

Synapse. 2010 Apr;64(4):301-12. doi: 10.1002/syn.20718.

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