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Items: 45


Nup98 regulation of histone methylation promotes normal gene expression and may drive leukemogenesis.

Sump B, Brickner JH.

Genes Dev. 2017 Nov 15;31(22):2201-2203. doi: 10.1101/gad.310359.117. Review.


Genetic and Epigenetic Strategies Potentiate Gal4 Activation to Enhance Fitness in Recently Diverged Yeast Species.

Sood V, Brickner JH.

Curr Biol. 2017 Dec 4;27(23):3591-3602.e3. doi: 10.1016/j.cub.2017.10.035. Epub 2017 Nov 16.


Nuclear Pore Complexes: A Scaffold Regulating Developmental Transcription?

Satomura A, Brickner JH.

Trends Cell Biol. 2017 Sep;27(9):621-622. doi: 10.1016/j.tcb.2017.07.002. Epub 2017 Jul 19.


Epigenetic Transcriptional Memory of GAL Genes Depends on Growth in Glucose and the Tup1 Transcription Factor in Saccharomyces cerevisiae.

Sood V, Cajigas I, D'Urso A, Light WH, Brickner JH.

Genetics. 2017 Aug;206(4):1895-1907. doi: 10.1534/genetics.117.201632. Epub 2017 Jun 12.


The dynamic three-dimensional organization of the diploid yeast genome.

Kim S, Liachko I, Brickner DG, Cook K, Noble WS, Brickner JH, Shendure J, Dunham MJ.

Elife. 2017 May 24;6. pii: e23623. doi: 10.7554/eLife.23623.


Memory Is the Treasury and Guardian of All Things.

D'Urso A, Brickner JH.

Mol Cell. 2017 Apr 6;66(1):5-6. doi: 10.1016/j.molcel.2017.03.012.


Epigenetic transcriptional memory.

D'Urso A, Brickner JH.

Curr Genet. 2017 Jun;63(3):435-439. doi: 10.1007/s00294-016-0661-8. Epub 2016 Nov 2. Review.


Subnuclear positioning and interchromosomal clustering of the GAL1-10 locus are controlled by separable, interdependent mechanisms.

Brickner DG, Sood V, Tutucci E, Coukos R, Viets K, Singer RH, Brickner JH.

Mol Biol Cell. 2016 Oct 1;27(19):2980-93. doi: 10.1091/mbc.E16-03-0174. Epub 2016 Aug 3.


Transcription factors dynamically control the spatial organization of the yeast genome.

Randise-Hinchliff C, Brickner JH.

Nucleus. 2016 Jul 3;7(4):369-74. doi: 10.1080/19491034.2016.1212797. Epub 2016 Jul 21. Review.


Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory.

D'Urso A, Takahashi YH, Xiong B, Marone J, Coukos R, Randise-Hinchliff C, Wang JP, Shilatifard A, Brickner JH.

Elife. 2016 Jun 23;5. pii: e16691. doi: 10.7554/eLife.16691.


Strategies to regulate transcription factor-mediated gene positioning and interchromosomal clustering at the nuclear periphery.

Randise-Hinchliff C, Coukos R, Sood V, Sumner MC, Zdraljevic S, Meldi Sholl L, Garvey Brickner D, Ahmed S, Watchmaker L, Brickner JH.

J Cell Biol. 2016 Mar 14;212(6):633-46. doi: 10.1083/jcb.201508068. Epub 2016 Mar 7.


INO1 transcriptional memory leads to DNA zip code-dependent interchromosomal clustering.

Brickner DG, Coukos R, Brickner JH.

Microb Cell. 2015 Dec;2(12):481-490. Epub 2015 Nov 13.


Approaches to studying subnuclear organization and gene-nuclear pore interactions.

Egecioglu DE, D'Urso A, Brickner DG, Light WH, Brickner JH.

Methods Cell Biol. 2014;122:463-85. doi: 10.1016/B978-0-12-417160-2.00021-7.


Mechanisms of epigenetic memory.

D'Urso A, Brickner JH.

Trends Genet. 2014 Jun;30(6):230-6. doi: 10.1016/j.tig.2014.04.004. Epub 2014 Apr 26. Review.


Nuclear pore interactions with the genome.

Sood V, Brickner JH.

Curr Opin Genet Dev. 2014 Apr;25:43-9. doi: 10.1016/j.gde.2013.11.018. Epub 2014 Jan 28. Review.


Nuclear pore proteins regulate chromatin structure and transcriptional memory by a conserved mechanism.

Light WH, Brickner JH.

Nucleus. 2013 Sep-Oct;4(5):357-60. doi: 10.4161/nucl.26209. Epub 2013 Aug 19. Review.


A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory.

Light WH, Freaney J, Sood V, Thompson A, D'Urso A, Horvath CM, Brickner JH.

PLoS Biol. 2013;11(3):e1001524. doi: 10.1371/journal.pbio.1001524. Epub 2013 Mar 26.


Vps factors are required for efficient transcription elongation in budding yeast.

Gaur NA, Hasek J, Brickner DG, Qiu H, Zhang F, Wong CM, Malcova I, Vasicova P, Brickner JH, Hinnebusch AG.

Genetics. 2013 Mar;193(3):829-51. doi: 10.1534/genetics.112.146308. Epub 2013 Jan 18.


A new direction for gene looping.

Randise-Hinchliff CE, Brickner JH.

Dev Cell. 2012 Nov 13;23(5):919-21. doi: 10.1016/j.devcel.2012.10.024.


Interchromosomal clustering of active genes at the nuclear pore complex.

Brickner DG, Brickner JH.

Nucleus. 2012 Nov-Dec;3(6):487-92. doi: 10.4161/nucl.22663. Epub 2012 Oct 25.


Transcription factor binding to a DNA zip code controls interchromosomal clustering at the nuclear periphery.

Brickner DG, Ahmed S, Meldi L, Thompson A, Light W, Young M, Hickman TL, Chu F, Fabre E, Brickner JH.

Dev Cell. 2012 Jun 12;22(6):1234-46. doi: 10.1016/j.devcel.2012.03.012. Epub 2012 May 10.


Nuclear architecture: the cell biology of a laminopathy.

Brickner JH.

Curr Biol. 2011 Oct 11;21(19):R807-9. doi: 10.1016/j.cub.2011.09.006.


Compartmentalization of the nucleus.

Meldi L, Brickner JH.

Trends Cell Biol. 2011 Dec;21(12):701-8. doi: 10.1016/j.tcb.2011.08.001. Epub 2011 Sep 6. Review.


Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat.

Leung A, Cajigas I, Jia P, Ezhkova E, Brickner JH, Zhao Z, Geng F, Tansey WP.

Mol Biol Cell. 2011 Aug 1;22(15):2741-53. doi: 10.1091/mbc.E11-05-0426. Epub 2011 Jun 16.


A role for DNA sequence in controlling the spatial organization of the genome.

Ahmed S, Brickner JH.

Nucleus. 2010 Sep-Oct;1(5):402-6. doi: 10.4161/nucl.1.5.12637.


Gene positioning and expression.

Egecioglu D, Brickner JH.

Curr Opin Cell Biol. 2011 Jun;23(3):338-45. doi: 10.1016/ Epub 2011 Feb 1. Review.


Gene positioning is regulated by phosphorylation of the nuclear pore complex by Cdk1.

Brickner DG, Brickner JH.

Cell Cycle. 2011 Feb 1;10(3):392-5. Epub 2011 Feb 1.


Quantitative localization of chromosomal loci by immunofluorescence.

Brickner DG, Light W, Brickner JH.

Methods Enzymol. 2010;470:569-80. doi: 10.1016/S0076-6879(10)70022-7. Epub 2010 Mar 1.


Interaction of a DNA zip code with the nuclear pore complex promotes H2A.Z incorporation and INO1 transcriptional memory.

Light WH, Brickner DG, Brand VR, Brickner JH.

Mol Cell. 2010 Oct 8;40(1):112-25. doi: 10.1016/j.molcel.2010.09.007.


Cdk phosphorylation of a nucleoporin controls localization of active genes through the cell cycle.

Brickner DG, Brickner JH.

Mol Biol Cell. 2010 Oct 1;21(19):3421-32. doi: 10.1091/mbc.E10-01-0065. Epub 2010 Aug 11.


Transcriptional memory: staying in the loop.

Brickner JH.

Curr Biol. 2010 Jan 12;20(1):R20-1. doi: 10.1016/j.cub.2009.11.013.


DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery.

Ahmed S, Brickner DG, Light WH, Cajigas I, McDonough M, Froyshteter AB, Volpe T, Brickner JH.

Nat Cell Biol. 2010 Feb;12(2):111-8. doi: 10.1038/ncb2011. Epub 2010 Jan 24. Erratum in: Nat Cell Biol. 2010 Mar;12(3):306.


Cohesinopathy mutations disrupt the subnuclear organization of chromatin.

Gard S, Light W, Xiong B, Bose T, McNairn AJ, Harris B, Fleharty B, Seidel C, Brickner JH, Gerton JL.

J Cell Biol. 2009 Nov 16;187(4):455-62. doi: 10.1083/jcb.200906075. Epub 2009 Nov 9. Erratum in: J Cell Biol. 2009 Nov 30;187(5):749.


Transcriptional memory at the nuclear periphery.

Brickner JH.

Curr Opin Cell Biol. 2009 Feb;21(1):127-33. doi: 10.1016/ Epub 2009 Jan 30. Review.


Regulation and epigenetic control of transcription at the nuclear periphery.

Ahmed S, Brickner JH.

Trends Genet. 2007 Aug;23(8):396-402. Epub 2007 Jun 12. Review.


H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state.

Brickner DG, Cajigas I, Fondufe-Mittendorf Y, Ahmed S, Lee PC, Widom J, Brickner JH.

PLoS Biol. 2007 Apr;5(4):e81.


Eisosomes mark static sites of endocytosis.

Walther TC, Brickner JH, Aguilar PS, Bernales S, Pantoja C, Walter P.

Nature. 2006 Feb 23;439(7079):998-1003.


Structural basis of FFAT motif-mediated ER targeting.

Kaiser SE, Brickner JH, Reilein AR, Fenn TD, Walter P, Brunger AT.

Structure. 2005 Jul;13(7):1035-45.


Gene recruitment of the activated INO1 locus to the nuclear membrane.

Brickner JH, Walter P.

PLoS Biol. 2004 Nov;2(11):e342. Epub 2004 Sep 28.


Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteins.

Sipos G, Brickner JH, Brace EJ, Chen L, Rambourg A, Kepes F, Fuller RS.

Mol Biol Cell. 2004 Jul;15(7):3196-209. Epub 2004 Apr 16.


The Tlg SNARE complex is required for TGN homotypic fusion.

Brickner JH, Blanchette JM, Sipos G, Fuller RS.

J Cell Biol. 2001 Dec 10;155(6):969-78. Epub 2001 Dec 10.


Yeast TFIIE. Cloning, expression, and homology to vertebrate proteins.

Feaver WJ, Henry NL, Bushnell DA, Sayre MH, Brickner JH, Gileadi O, Kornberg RD.

J Biol Chem. 1994 Nov 4;269(44):27549-53.

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