Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 58

1.

Genetic Deletion of Hesx1 Promotes Exit from the Pluripotent State and Impairs Developmental Diapause.

Pozzi S, Bowling S, Apps J, Brickman JM, Rodriguez TA, Martinez-Barbera JP.

Stem Cell Reports. 2019 Dec 10;13(6):970-979. doi: 10.1016/j.stemcr.2019.10.014. Epub 2019 Nov 21.

2.

Naïve human pluripotent stem cells respond to Wnt, Nodal and LIF signalling to produce expandable naïve extra-embryonic endoderm.

Linneberg-Agerholm M, Wong YF, Romero Herrera JA, Monteiro RS, Anderson KGV, Brickman JM.

Development. 2019 Dec 16;146(24). pii: dev180620. doi: 10.1242/dev.180620.

PMID:
31740534
3.

Dynamic lineage priming is driven via direct enhancer regulation by ERK.

Hamilton WB, Mosesson Y, Monteiro RS, Emdal KB, Knudsen TE, Francavilla C, Barkai N, Olsen JV, Brickman JM.

Nature. 2019 Nov;575(7782):355-360. doi: 10.1038/s41586-019-1732-z. Epub 2019 Nov 6.

PMID:
31695196
4.

An automated microfluidic device for time-lapse imaging of mouse embryonic stem cells.

Laing AF, Tirumala V, Hegarty E, Mondal S, Zhao P, Hamilton WB, Brickman JM, Ben-Yakar A.

Biomicrofluidics. 2019 Sep 17;13(5):054102. doi: 10.1063/1.5124057. eCollection 2019 Sep.

PMID:
31558920
5.

HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development.

Gauvrit S, Villasenor A, Strilic B, Kitchen P, Collins MM, Marín-Juez R, Guenther S, Maischein HM, Fukuda N, Canham MA, Brickman JM, Bogue CW, Jayaraman PS, Stainier DYR.

Nat Commun. 2018 Jul 13;9(1):2704. doi: 10.1038/s41467-018-05039-1.

6.

Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome.

Weinert BT, Narita T, Satpathy S, Srinivasan B, Hansen BK, Schölz C, Hamilton WB, Zucconi BE, Wang WW, Liu WR, Brickman JM, Kesicki EA, Lai A, Bromberg KD, Cole PA, Choudhary C.

Cell. 2018 Jun 28;174(1):231-244.e12. doi: 10.1016/j.cell.2018.04.033. Epub 2018 May 24.

7.

Insulin fine-tunes self-renewal pathways governing naive pluripotency and extra-embryonic endoderm.

Anderson KGV, Hamilton WB, Roske FV, Azad A, Knudsen TE, Canham MA, Forrester LM, Brickman JM.

Nat Cell Biol. 2017 Oct;19(10):1164-1177. doi: 10.1038/ncb3617. Epub 2017 Sep 25.

PMID:
28945231
8.

Four simple rules that are sufficient to generate the mammalian blastocyst.

Nissen SB, Perera M, Gonzalez JM, Morgani SM, Jensen MH, Sneppen K, Brickman JM, Trusina A.

PLoS Biol. 2017 Jul 12;15(7):e2000737. doi: 10.1371/journal.pbio.2000737. eCollection 2017 Jul.

9.

Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny.

Migueles RP, Shaw L, Rodrigues NP, May G, Henseleit K, Anderson KG, Goker H, Jones CM, de Bruijn MF, Brickman JM, Enver T.

Dev Biol. 2017 Apr 15;424(2):236-245. doi: 10.1016/j.ydbio.2016.12.021. Epub 2017 Feb 9.

10.

Surveillance for Secure Differentiation.

Hamilton WB, Brickman JM.

Cell Stem Cell. 2017 Jan 5;20(1):3-5. doi: 10.1016/j.stem.2016.12.011.

11.

Properties of embryoid bodies.

Brickman JM, Serup P.

Wiley Interdiscip Rev Dev Biol. 2017 Mar;6(2). doi: 10.1002/wdev.259. Epub 2016 Dec 2. Review.

PMID:
27911036
12.

Polycomb enables primitive endoderm lineage priming in embryonic stem cells.

Illingworth RS, Hölzenspies JJ, Roske FV, Bickmore WA, Brickman JM.

Elife. 2016 Oct 10;5. pii: e14926. doi: 10.7554/eLife.14926.

13.

Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency.

Martin Gonzalez J, Morgani SM, Bone RA, Bonderup K, Abelchian S, Brakebusch C, Brickman JM.

Stem Cell Reports. 2016 Aug 9;7(2):177-91. doi: 10.1016/j.stemcr.2016.07.009.

14.

Differentiation of Mouse Embryonic Stem Cells into Ventral Foregut Precursors.

Rothová M, Hölzenspies JJ, Livigni A, Villegas SN, Brickman JM.

Curr Protoc Stem Cell Biol. 2016 Feb 3;36:1G.3.1-1G.3.12. doi: 10.1002/9780470151808.sc01g03s36. Review.

PMID:
26840225
15.

Erratum to: Resolving Heterogeneity: Fluorescence-Activated Cell Sorting of Dynamic Cell Populations from Feeder-Free Mouse Embryonic Stem Cell Culture.

Hölzenspies J, Cruz GD, Brickman JM.

Methods Mol Biol. 2016;1341:445. doi: 10.1007/7651_2015_313. No abstract available.

PMID:
26515453
16.

LIF supports primitive endoderm expansion during pre-implantation development.

Morgani SM, Brickman JM.

Development. 2015 Oct 15;142(20):3488-99. doi: 10.1242/dev.125021. Epub 2015 Sep 22.

17.

Erk signaling suppresses embryonic stem cell self-renewal to specify endoderm.

Hamilton WB, Brickman JM.

Cell Rep. 2014 Dec 24;9(6):2056-70. doi: 10.1016/j.celrep.2014.11.032. Epub 2014 Dec 18.

18.

Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression.

Laing AF, Lowell S, Brickman JM.

Dev Biol. 2015 Jan 1;397(1):56-66. doi: 10.1016/j.ydbio.2014.10.007. Epub 2014 Oct 23.

19.

The molecular underpinnings of totipotency.

Morgani SM, Brickman JM.

Philos Trans R Soc Lond B Biol Sci. 2014 Dec 5;369(1657). pii: 20130549. doi: 10.1098/rstb.2013.0549. Review.

20.

The POU-er of gene nomenclature.

Frankenberg SR, Frank D, Harland R, Johnson AD, Nichols J, Niwa H, Schöler HR, Tanaka E, Wylie C, Brickman JM.

Development. 2014 Aug;141(15):2921-3. doi: 10.1242/dev.108407.

21.

PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix.

Villegas SN, Rothová M, Barrios-Llerena ME, Pulina M, Hadjantonakis AK, Le Bihan T, Astrof S, Brickman JM.

Elife. 2013 Dec 24;2:e00806. doi: 10.7554/eLife.00806.

22.

Survival of the fattest.

Morgani SM, Brickman JM.

Elife. 2013 Nov 26;2:e01760. doi: 10.7554/eLife.01760.

23.

A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance.

Livigni A, Peradziryi H, Sharov AA, Chia G, Hammachi F, Migueles RP, Sukparangsi W, Pernagallo S, Bradley M, Nichols J, Ko MSH, Brickman JM.

Curr Biol. 2013 Nov 18;23(22):2233-2244. doi: 10.1016/j.cub.2013.09.048. Epub 2013 Nov 7.

24.

Oct4: the final frontier, differentiation defining pluripotency.

Livigni A, Brickman JM.

Dev Cell. 2013 Jun 24;25(6):547-8. doi: 10.1016/j.devcel.2013.06.002.

25.

Totipotent embryonic stem cells arise in ground-state culture conditions.

Morgani SM, Canham MA, Nichols J, Sharov AA, Migueles RP, Ko MS, Brickman JM.

Cell Rep. 2013 Jun 27;3(6):1945-57. doi: 10.1016/j.celrep.2013.04.034. Epub 2013 Jun 6.

26.

Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency.

Hammachi F, Morrison GM, Sharov AA, Livigni A, Narayan S, Papapetrou EP, O'Malley J, Kaji K, Ko MS, Ptashne M, Brickman JM.

Cell Rep. 2012 Feb 23;1(2):99-109. doi: 10.1016/j.celrep.2011.12.002. Epub 2012 Feb 16.

27.

HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche.

Jackson M, Axton RA, Taylor AH, Wilson JA, Gordon-Keylock SA, Kokkaliaris KD, Brickman JM, Schulz H, Hummel O, Hubner N, Forrester LM.

Stem Cells. 2012 Feb;30(2):150-60. doi: 10.1002/stem.782. Erratum in: Stem Cells. 2012 Jun;30(6):1311-2.

28.

Gene expression heterogeneities in embryonic stem cell populations: origin and function.

Martinez Arias A, Brickman JM.

Curr Opin Cell Biol. 2011 Dec;23(6):650-6. doi: 10.1016/j.ceb.2011.09.007. Epub 2011 Oct 5. Review.

PMID:
21982544
29.

A wider context for gene trap mutagenesis.

Brickman JM, Tsakiridis A, To C, Stanford WL.

Methods Enzymol. 2010;477:271-95. doi: 10.1016/S0076-6879(10)77014-2.

PMID:
20699146
30.

Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript.

Canham MA, Sharov AA, Ko MS, Brickman JM.

PLoS Biol. 2010 May 25;8(5):e1000379. doi: 10.1371/journal.pbio.1000379.

31.

FGF signalling as a mediator of lineage transitions--evidence from embryonic stem cell differentiation.

Villegas SN, Canham M, Brickman JM.

J Cell Biochem. 2010 May;110(1):10-20. doi: 10.1002/jcb.22536. Review.

PMID:
20336694
32.

Investigation of microsphere-mediated cellular delivery by chemical, microscopic and gene expression analysis.

Alexander LM, Pernagallo S, Livigni A, Sánchez-Martín RM, Brickman JM, Bradley M.

Mol Biosyst. 2010 Feb;6(2):399-409. doi: 10.1039/b914428e. Epub 2009 Nov 26.

PMID:
20094660
33.

Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells.

Tsakiridis A, Tzouanacou E, Rahman A, Colby D, Axton R, Chambers I, Wilson V, Forrester L, Brickman JM.

Nucleic Acids Res. 2009 Oct;37(19):e129. doi: 10.1093/nar/gkp640. Epub 2009 Aug 19.

34.

Microsphere-based tracing and molecular delivery in embryonic stem cells.

Tsakiridis A, Alexander LM, Gennet N, Sanchez-Martin RM, Livigni A, Li M, Bradley M, Brickman JM.

Biomaterials. 2009 Oct;30(29):5853-61. doi: 10.1016/j.biomaterials.2009.06.024. Epub 2009 Jul 15.

PMID:
19608269
35.

Differentiation of embryonic stem cells into anterior definitive endoderm.

Livigni A, Villegas SN, Oikonomopoulou I, Rahman A, Morrison GM, Brickman JM.

Curr Protoc Stem Cell Biol. 2009 Jul;Chapter 1:Unit 1G.3. doi: 10.1002/9780470151808.sc01g03s10.

PMID:
19585461
36.

Microspheres as a vehicle for biomolecule delivery to neural stem cells.

Gennet N, Alexander LM, Sánchez-Martín RM, Behrendt JM, Sutherland AJ, Brickman JM, Bradley M, Li M.

N Biotechnol. 2009 Sep;25(6):442-9. doi: 10.1016/j.nbt.2009.05.006. Epub 2009 Jun 11.

PMID:
19524076
37.

Microsphere-mediated protein delivery into cells.

Sanchez-Martin RM, Alexander L, Muzerelle M, Cardenas-Maestre JM, Tsakiridis A, Brickman JM, Bradley M.

Chembiochem. 2009 Jun 15;10(9):1453-6. doi: 10.1002/cbic.200900136. No abstract available.

PMID:
19444829
38.

Anterior definitive endoderm from ESCs reveals a role for FGF signaling.

Morrison GM, Oikonomopoulou I, Migueles RP, Soneji S, Livigni A, Enver T, Brickman JM.

Cell Stem Cell. 2008 Oct 9;3(4):402-15. doi: 10.1016/j.stem.2008.07.021.

39.

Inhibition of cortical neuron differentiation by Groucho/TLE1 requires interaction with WRPW, but not Eh1, repressor peptides.

Buscarlet M, Perin A, Laing A, Brickman JM, Stifani S.

J Biol Chem. 2008 Sep 5;283(36):24881-8. doi: 10.1074/jbc.M800722200. Epub 2008 Jul 8.

40.

A novel triple fusion reporter system for use in gene trap mutagenesis.

Tsakiridis A, Tzouanacou E, Larralde O, Watts TM, Wilson V, Forrester L, Brickman JM.

Genesis. 2007 Jun;45(6):353-60.

PMID:
17492751
41.

Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal.

Zamparini AL, Watts T, Gardner CE, Tomlinson SR, Johnston GI, Brickman JM.

Development. 2006 Sep;133(18):3709-22.

42.
43.

Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.

Sousa-Nunes R, Rana AA, Kettleborough R, Brickman JM, Clements M, Forrest A, Grimmond S, Avner P, Smith JC, Dunwoodie SL, Beddington RS.

Genome Res. 2003 Dec;13(12):2609-20. Epub 2003 Nov 12.

44.

A homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressor-corepressor interaction.

Carvalho LR, Woods KS, Mendonca BB, Marcal N, Zamparini AL, Stifani S, Brickman JM, Arnhold IJ, Dattani MT.

J Clin Invest. 2003 Oct;112(8):1192-201.

45.

Pluripotency and tumorigenicity.

Brickman JM, Burdon TG.

Nat Genet. 2002 Dec;32(4):557-8. No abstract available.

PMID:
12457185
46.

Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality.

Roberts C, Sutherland HF, Farmer H, Kimber W, Halford S, Carey A, Brickman JM, Wynshaw-Boris A, Scambler PJ.

Mol Cell Biol. 2002 Apr;22(7):2318-28.

47.

Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders.

Brickman JM, Clements M, Tyrell R, McNay D, Woods K, Warner J, Stewart A, Beddington RS, Dattani M.

Development. 2001 Dec;128(24):5189-99.

48.

Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia.

Thomas PQ, Dattani MT, Brickman JM, McNay D, Warne G, Zacharin M, Cameron F, Hurst J, Woods K, Dunger D, Stanhope R, Forrest S, Robinson IC, Beddington RS.

Hum Mol Genet. 2001 Jan 1;10(1):39-45.

PMID:
11136712
49.

Molecular genetics of septo-optic dysplasia.

Dattani ML, Martinez-Barbera J, Thomas PQ, Brickman JM, Gupta R, Wales JK, Hindmarsh PC, Beddington RS, Robinson IC.

Horm Res. 2000;53 Suppl 1:26-33. Review.

PMID:
10895039
50.

Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function.

Brickman JM, Jones CM, Clements M, Smith JC, Beddington RS.

Development. 2000 Jun;127(11):2303-15.

Supplemental Content

Loading ...
Support Center