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Items: 1 to 50 of 69

1.

Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells.

Mukhamedova N, Hoang A, Dragoljevic D, Dubrovsky L, Pushkarsky T, Low H, Ditiatkovski M, Fu Y, Ohkawa R, Meikle PJ, Horvath A, Brichacek B, Miller YI, Murphy A, Bukrinsky M, Sviridov D.

PLoS Pathog. 2019 Jul 25;15(7):e1007907. doi: 10.1371/journal.ppat.1007907. eCollection 2019 Jul.

2.

Short Communication: Accumulation of Neutral Lipids in Liver and Aorta of Nef-Transgenic Mice.

Pushkarsky T, Shilov E, Kruglova N, Naumann R, Brichacek B, Jennelle L, Sviridov D, Kruglov A, Nedospasov SA, Bukrinsky M.

AIDS Res Hum Retroviruses. 2017 Jan;33(1):57-60. doi: 10.1089/AID.2016.0128. Epub 2016 Oct 25.

3.

Interaction Between HIV-1 Nef and Calnexin: From Modeling to Small Molecule Inhibitors Reversing HIV-Induced Lipid Accumulation.

Hunegnaw R, Vassylyeva M, Dubrovsky L, Pushkarsky T, Sviridov D, Anashkina AA, Üren A, Brichacek B, Vassylyev DG, Adzhubei AA, Bukrinsky M.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1758-71. doi: 10.1161/ATVBAHA.116.307997. Epub 2016 Jul 28.

4.

Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells.

Santos S, Obukhov Y, Nekhai S, Pushkarsky T, Brichacek B, Bukrinsky M, Iordanskiy S.

Virology. 2016 Oct;497:11-22. doi: 10.1016/j.virol.2016.06.023. Epub 2016 Jul 12.

5.

Live Cell Imaging of ABCA1 Downregulation by HIV-1 Nef in an Experimental Model of HeLa ABCA1-GFP.

Siegel J, Darwish C, Popratiloff A, Bukrinsky M, Brichacek B.

AIDS Res Hum Retroviruses. 2016 Sep;32(9):872-3. doi: 10.1089/aid.2015.0362. Epub 2016 May 2. No abstract available.

6.

Analysis of ABCA1 and Cholesterol Efflux in HIV-Infected Cells.

Mukhamedova N, Brichacek B, Darwish C, Popratiloff A, Sviridov D, Bukrinsky M.

Methods Mol Biol. 2016;1354:281-92. doi: 10.1007/978-1-4939-3046-3_19.

7.

HIV-1 infection of macrophages induces retention of cholesterol transporter ABCA1 in the endoplasmic reticulum.

Brichacek B, Darwish C, Popratiloff A, Dubrovsky L, Bukrinsky M.

AIDS Res Hum Retroviruses. 2014 Oct;30(10):947-8. doi: 10.1089/aid.2014.0156. Epub 2014 Sep 8. No abstract available.

8.

HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin.

Jennelle L, Hunegnaw R, Dubrovsky L, Pushkarsky T, Fitzgerald ML, Sviridov D, Popratiloff A, Brichacek B, Bukrinsky M.

J Biol Chem. 2014 Oct 17;289(42):28870-84. doi: 10.1074/jbc.M114.583591. Epub 2014 Aug 28.

9.

In vivo evaluation of safety and toxicity of a Lactobacillus jensenii producing modified cyanovirin-N in a rhesus macaque vaginal challenge model.

Brichacek B, Lagenaur LA, Lee PP, Venzon D, Hamer DH.

PLoS One. 2013 Nov 12;8(11):e78817. doi: 10.1371/journal.pone.0078817. eCollection 2013.

10.

The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis.

Trachtenberg A, Pushkarsky T, Heine S, Constant S, Brichacek B, Bukrinsky M.

BMC Res Notes. 2011 Oct 11;4:396. doi: 10.1186/1756-0500-4-396.

11.

Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus.

Lagenaur LA, Sanders-Beer BE, Brichacek B, Pal R, Liu X, Liu Y, Yu R, Venzon D, Lee PP, Hamer DH.

Mucosal Immunol. 2011 Nov;4(6):648-57. doi: 10.1038/mi.2011.30. Epub 2011 Jul 6.

12.

Contrasting roles for TLR ligands in HIV-1 pathogenesis.

Brichacek B, Vanpouille C, Kiselyeva Y, Biancotto A, Merbah M, Hirsch I, Lisco A, Grivel JC, Margolis L.

PLoS One. 2010 Sep 20;5(9). pii: e12831. doi: 10.1371/journal.pone.0012831.

13.

Significantly reduced CCR5-tropic HIV-1 replication in vitro in cells from subjects previously immunized with Vaccinia Virus.

Weinstein RS, Weinstein MM, Alibek K, Bukrinsky MI, Brichacek B.

BMC Immunol. 2010 May 18;11:23. doi: 10.1186/1471-2172-11-23.

14.

HIV-1 sexual transmission: early events of HIV-1 infection of human cervico-vaginal tissue in an optimized ex vivo model.

Saba E, Grivel JC, Vanpouille C, Brichacek B, Fitzgerald W, Margolis L, Lisco A.

Mucosal Immunol. 2010 May;3(3):280-90. doi: 10.1038/mi.2010.2. Epub 2010 Feb 10.

15.

A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2.

Vanpouille C, Lisco A, Derudas M, Saba E, Grivel JC, Brichacek B, Scrimieri F, Schinazi R, Schols D, McGuigan C, Balzarini J, Margolis L.

J Infect Dis. 2010 Feb 15;201(4):635-43. doi: 10.1086/650343.

16.

Movements of HIV-virions in human cervical mucus.

Boukari H, Brichacek B, Stratton P, Mahoney SF, Lifson JD, Margolis L, Nossal R.

Biomacromolecules. 2009 Sep 14;10(9):2482-8. doi: 10.1021/bm900344q.

17.

Toxoplasma gondii inhibits R5 HIV-1 replication in human lymphoid tissues ex vivo.

Sassi A, Brichacek B, Hieny S, Yarovinsky F, Golding H, Grivel JC, Sher A, Margolis L.

Microbes Infect. 2009 Dec;11(14-15):1106-13. doi: 10.1016/j.micinf.2009.08.004. Epub 2009 Aug 9.

18.

Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase.

Tchesnokov EP, Obikhod A, Massud I, Lisco A, Vanpouille C, Brichacek B, Balzarini J, McGuigan C, Derudas M, Margolis L, Schinazi RF, Götte M.

J Biol Chem. 2009 Aug 7;284(32):21496-504. doi: 10.1074/jbc.M109.024026. Epub 2009 Jun 9.

19.

A highly sensitive and dynamic immunofluorescent cytometric bead assay for the detection of HIV-1 p24.

Biancotto A, Brichacek B, Chen SS, Fitzgerald W, Lisco A, Vanpouille C, Margolis L, Grivel JC.

J Virol Methods. 2009 Apr;157(1):98-101. doi: 10.1016/j.jviromet.2008.11.013. Epub 2009 Jan 6.

20.

Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.

Lisco A, Vanpouille C, Tchesnokov EP, Grivel JC, Biancotto A, Brichacek B, Elliott J, Fromentin E, Shattock R, Anton P, Gorelick R, Balzarini J, McGuigan C, Derudas M, Götte M, Schinazi RF, Margolis L.

Cell Host Microbe. 2008 Sep 11;4(3):260-270. doi: 10.1016/j.chom.2008.07.008.

21.

Interactions between human immunodeficiency virus type 1 and vaccinia virus in human lymphoid tissue ex vivo.

Vanpouille C, Biancotto A, Lisco A, Brichacek B.

J Virol. 2007 Nov;81(22):12458-64. Epub 2007 Sep 5.

22.

Long-term changes of serum chemokine levels in vaccinated military personnel.

Brichacek B, Vanpouille C, Trachtenberg AJ, Pushkarsky T, Dubrovsky L, Martin G, Simon G, Bukrinsky M.

BMC Immunol. 2006 Sep 11;7:21.

23.

Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60.

Pushkarsky T, Yurchenko V, Vanpouille C, Brichacek B, Vaisman I, Hatakeyama S, Nakayama KI, Sherry B, Bukrinsky MI.

J Biol Chem. 2005 Jul 29;280(30):27866-71. Epub 2005 Jun 9.

24.

HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection.

Swingler S, Brichacek B, Jacque JM, Ulich C, Zhou J, Stevenson M.

Nature. 2003 Jul 10;424(6945):213-9.

PMID:
12853962
25.

Highly active antiretroviral therapy and beta-chemokines.

Brichacek B, Bukrinsky M.

Clin Exp Immunol. 2002 Nov;130(2):169-71. No abstract available.

26.

Evidence for a cytopathogenicity determinant in HIV-1 Vpr.

Somasundaran M, Sharkey M, Brichacek B, Luzuriaga K, Emerman M, Sullivan JL, Stevenson M.

Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9503-8. Epub 2002 Jul 1.

27.

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages.

Swingler S, Mann A, Jacqué J, Brichacek B, Sasseville VG, Williams K, Lackner AA, Janoff EN, Wang R, Fisher D, Stevenson M.

Nat Med. 1999 Sep;5(9):997-103.

PMID:
10470075
28.

Vpx is required for dissemination and pathogenesis of SIV(SM) PBj: evidence of macrophage-dependent viral amplification.

Hirsch VM, Sharkey ME, Brown CR, Brichacek B, Goldstein S, Wakefield J, Byrum R, Elkins WR, Hahn BH, Lifson JD, Stevenson M.

Nat Med. 1998 Dec;4(12):1401-8.

PMID:
9846578
29.
30.

Modulation of HIV-1 infectivity by MAPK, a virion-associated kinase.

Jacqué JM, Mann A, Enslen H, Sharova N, Brichacek B, Davis RJ, Stevenson M.

EMBO J. 1998 May 1;17(9):2607-18.

31.

Quantitative competitive RNA PCR for quantitation of virion-associated HIV-1 RNA.

Brichacek B, Stevenson M.

Methods. 1997 Aug;12(4):294-9.

PMID:
9245609
32.

A yeast artificial chromosome (YAC) contig encompassing the critical region of the X-linked lymphoproliferative disease (XLP) locus.

Lanyi A, Li B, Li S, Talmadge CB, Brichacek B, Davis JR, Kozel BA, Trask B, van den Engh G, Uzvolgyi E, Stanbridge EJ, Nelson DL, Chinault C, Heslop H, Gross TG, Seemayer TA, Klein G, Purtilo DT, Sumegi J.

Genomics. 1997 Jan 1;39(1):55-65.

PMID:
9027486
33.

Increased plasma human immunodeficiency virus type 1 burden following antigenic challenge with pneumococcal vaccine.

Brichacek B, Swindells S, Janoff EN, Pirruccello S, Stevenson M.

J Infect Dis. 1996 Dec;174(6):1191-9.

PMID:
8940208
34.

Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM).

Fletcher TM 3rd, Brichacek B, Sharova N, Newman MA, Stivahtis G, Sharp PM, Emerman M, Hahn BH, Stevenson M.

EMBO J. 1996 Nov 15;15(22):6155-65.

35.

Regulation and characterization of the interferon-alpha present in patients with advanced human immunodeficiency virus type 1 disease.

Swindells S, Baldwin T, Kelly C, Baca-Regen L, Loomis L, Post D, Brichacek B, Stevenson M, Dominguez EA, Reddy R, Klein R, Liao MJ, Testa D, McDonald T, Bellanti J, Skurkovich S, Gendelman HE.

J Interferon Cytokine Res. 1996 Feb;16(2):127-37.

PMID:
8742365
36.

Molecular basis of cell cycle dependent HIV-1 replication. Implications for control of virus burden.

Stevenson M, Brichacek B, Heinzinger N, Swindells S, Pirruccello S, Janoff E, Emerman M.

Adv Exp Med Biol. 1995;374:33-45. Review.

PMID:
7572399
37.

X-linked lymphoproliferative disease.

Seemayer TA, Grierson H, Pirruccello SJ, Gross TG, Weisenburger DD, Davis J, Spiegel K, Brichacek B, Sumegi J.

Am J Dis Child. 1993 Nov;147(11):1242-5. Review. No abstract available.

PMID:
8237920
39.

Early activation of the proto-oncogene c-fgr during Epstein-Barr virus immortalization.

Okano M, Davis JR, Brichacek B, Yasuda N, Purtilo DT.

Cancer Lett. 1992 May 30;64(1):11-5.

PMID:
1317747
40.

HIV-1 infectivity of human carcinoma cell lines lacking CD4 receptors.

Brichacek B, Derderian C, Chermann JC, Hirsch I.

Cancer Lett. 1992 Mar 31;63(1):23-31.

PMID:
1313332
41.

HIV1 cytopathogenicity-genetic difference between direct cytotoxic and fusogenic effect.

Hirsch I, Salaun D, Brichacek B, Chermann JC.

Virology. 1992 Feb;186(2):647-54.

PMID:
1733106
42.

Presence of antibody reactive with synthetic peptide derived from L2 open reading frame of human papillomavirus types 6b and 11 in human sera.

Suchánková A, Ritter O, Hirsch I, Krchnák V, Kalos Z, Hamsíková E, Brichácek B, Vonka V.

Acta Virol. 1990 Sep;34(5):433-42.

PMID:
1705748
43.

Immunohistologic identification of Epstein-Barr virus-induced hepatitis reactivation after OKT-3 therapy following orthotopic liver transplant.

Markin RS, Wood RP, Shaw BW Jr, Brichacek B, Purtilo DT.

Am J Gastroenterol. 1990 Aug;85(8):1014-8.

PMID:
2165351
44.

[The presence of human papillomavirus deoxyribonucleic acid in tumors in the otorhinolaryngologic area].

Vonka R, Veselý J, Síbl O, Brichácek B.

Cas Lek Cesk. 1990 Mar 16;129(11):334-6. Czech.

PMID:
2340556
45.

[Colposcopic and cytological diagnosis of subclinical papillomavirus infections from the aspect of biopsies and hybridization tests].

Kanka J, Beková A, Brichácek B, Havránková A, Hirsch I, Krcmár M, Náprstková J, Rychterová J, Svoboda B, Vonka V.

Cesk Gynekol. 1990 Mar;55(2):109-13. Czech. No abstract available.

PMID:
2160863
46.

Presence and type specificity of papillomavirus antibodies demonstrable by immunoelectron microscopy tests in samples from patients with warts.

Anisimová E, Barták P, Vlcek D, Hirsch I, Brichácek B, Vonka V.

J Gen Virol. 1990 Feb;71 ( Pt 2):419-22.

PMID:
2155296
47.

Epstein-Barr virus nuclear antigen type 1 binding: electron microscopy.

Hirsch I, Reischig J, Benada O, Bartsch D, Brichácek B, Boguszaková L, Vonka V.

J Virol Methods. 1988 Dec;22(2-3):133-42.

PMID:
2851598
48.

Absence of cytomegalovirus, Epstein-Barr virus, and papillomavirus DNA from adenoma and adenocarcinoma of the colon.

Boguszaková L, Hirsch I, Brichácek B, Faltýn J, Fric P, Dvoráková H, Vonka V.

Acta Virol. 1988 Jul;32(4):303-8.

PMID:
2903634
49.

Hepatitis in fatal infectious mononucleosis.

Markin RS, Linder J, Zuerlein K, Mroczek E, Grierson HL, Brichacek B, Purtilo DT.

Gastroenterology. 1987 Dec;93(6):1210-7.

PMID:
3678738
50.

Thymic lesions in fatal infectious mononucleosis.

Mroczek EC, Seemayer TA, Grierson HL, Markin RS, Linder J, Brichacek B, Purtilo DT.

Clin Immunol Immunopathol. 1987 May;43(2):243-55.

PMID:
3568458

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