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Items: 1 to 50 of 66

1.

LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β.

Rossi M, Bucci G, Rizzotto D, Bordo D, Marzi MJ, Puppo M, Flinois A, Spadaro D, Citi S, Emionite L, Cilli M, Nicassio F, Inga A, Briata P, Gherzi R.

Nat Commun. 2019 Apr 29;10(1):1969. doi: 10.1038/s41467-019-09754-1.

2.

Corrigendum: Autoregulatory circuit of human rpL3 expression requires hnRNP H1, NPM and KHSRP.

Russo A, Catillo M, Esposito D, Briata P, Pietropaolo C, Russo G.

Nucleic Acids Res. 2017 Dec 1;45(21):12600. doi: 10.1093/nar/gkx1099. No abstract available.

3.

Resveratrol limits epithelial to mesenchymal transition through modulation of KHSRP/hnRNPA1-dependent alternative splicing in mammary gland cells.

Moshiri A, Puppo M, Rossi M, Gherzi R, Briata P.

Biochim Biophys Acta Gene Regul Mech. 2017 Mar;1860(3):291-298. doi: 10.1016/j.bbagrm.2017.01.001. Epub 2017 Jan 11.

PMID:
28088441
4.

miRNA-Mediated KHSRP Silencing Rewires Distinct Post-transcriptional Programs during TGF-β-Induced Epithelial-to-Mesenchymal Transition.

Puppo M, Bucci G, Rossi M, Giovarelli M, Bordo D, Moshiri A, Gorlero F, Gherzi R, Briata P.

Cell Rep. 2016 Jul 26;16(4):967-978. doi: 10.1016/j.celrep.2016.06.055. Epub 2016 Jul 7.

5.

Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease.

Briata P, Bordo D, Puppo M, Gorlero F, Rossi M, Perrone-Bizzozero N, Gherzi R.

Wiley Interdiscip Rev RNA. 2016 Mar-Apr;7(2):227-40. doi: 10.1002/wrna.1327. Epub 2015 Dec 27. Review.

6.

Retraction: The RNA-Binding Protein KSRP Promotes Decay of β-Catenin mRNA and Is Inactivated by PI3K-AKT Signaling.

Gherzi R, Trabucchi M, Ponassi M, Ruggiero T, Corte G, Moroni C, Chen CY, Khabar KS, Andersen JS, Briata P.

PLoS Biol. 2015 Nov 16;13(11):e1002314. doi: 10.1371/journal.pbio.1002314. eCollection 2015. No abstract available.

7.

H19 long noncoding RNA controls the mRNA decay promoting function of KSRP.

Giovarelli M, Bucci G, Ramos A, Bordo D, Wilusz CJ, Chen CY, Puppo M, Briata P, Gherzi R.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5023-8. doi: 10.1073/pnas.1415098111. Epub 2014 Nov 10.

8.

KSRP controls pleiotropic cellular functions.

Gherzi R, Chen CY, Ramos A, Briata P.

Semin Cell Dev Biol. 2014 Oct;34:2-8. doi: 10.1016/j.semcdb.2014.05.004. Epub 2014 May 17. Review.

PMID:
24845017
9.

KSRP and MicroRNA 145 are negative regulators of lipolysis in white adipose tissue.

Lin YY, Chou CF, Giovarelli M, Briata P, Gherzi R, Chen CY.

Mol Cell Biol. 2014 Jun;34(12):2339-49. doi: 10.1128/MCB.00042-14. Epub 2014 Apr 14.

10.

KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression.

Chou CF, Lin YY, Wang HK, Zhu X, Giovarelli M, Briata P, Gherzi R, Garvey WT, Chen CY.

Diabetes. 2014 Sep;63(9):2949-61. doi: 10.2337/db13-1901. Epub 2014 Apr 10.

11.

KSRP silencing favors neural differentiation of P19 teratocarcinoma cells.

Giovarelli M, Bucci G, Pasero M, Gherzi R, Briata P.

Biochim Biophys Acta. 2013 May;1829(5):469-79. doi: 10.1016/j.bbagrm.2013.02.008. Epub 2013 Feb 24.

PMID:
23462617
12.

Functional and molecular insights into KSRP function in mRNA decay.

Briata P, Chen CY, Ramos A, Gherzi R.

Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):689-94. doi: 10.1016/j.bbagrm.2012.11.003. Epub 2012 Nov 22. Review.

PMID:
23178464
13.

Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation.

Pasero M, Giovarelli M, Bucci G, Gherzi R, Briata P.

Cell Rep. 2012 Nov 29;2(5):1159-68. doi: 10.1016/j.celrep.2012.10.020. Epub 2012 Nov 21.

14.

Noncanonical G recognition mediates KSRP regulation of let-7 biogenesis.

Nicastro G, García-Mayoral MF, Hollingworth D, Kelly G, Martin SR, Briata P, Gherzi R, Ramos A.

Nat Struct Mol Biol. 2012 Dec;19(12):1282-6. doi: 10.1038/nsmb.2427. Epub 2012 Nov 11.

15.

Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP.

Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M.

PLoS Genet. 2012;8(7):e1002823. doi: 10.1371/journal.pgen.1002823. Epub 2012 Jul 26. Erratum in: PLoS Genet. 2012 Sep;8(9). doi:10.1371/annotation/c93e4b67-d237-48fb-aec7-0db398407bb4.

16.

KH domains with impaired nucleic acid binding as a tool for functional analysis.

Hollingworth D, Candel AM, Nicastro G, Martin SR, Briata P, Gherzi R, Ramos A.

Nucleic Acids Res. 2012 Aug;40(14):6873-86. doi: 10.1093/nar/gks368. Epub 2012 Apr 29.

17.

The role of KSRP in mRNA decay and microRNA precursor maturation.

Gherzi R, Chen CY, Trabucchi M, Ramos A, Briata P.

Wiley Interdiscip Rev RNA. 2010 Sep-Oct;1(2):230-9. doi: 10.1002/wrna.2. Epub 2010 May 6. Review.

PMID:
21935887
18.

PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis.

Briata P, Lin WJ, Giovarelli M, Pasero M, Chou CF, Trabucchi M, Rosenfeld MG, Chen CY, Gherzi R.

Cell Death Differ. 2012 Mar;19(3):478-87. doi: 10.1038/cdd.2011.117. Epub 2011 Sep 2.

19.

KSRP Promotes the Maturation of a Group of miRNA Precuresors.

Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG.

Adv Exp Med Biol. 2011;700:36-42. doi: 10.1007/978-1-4419-7823-3_4.

PMID:
21755471
20.

Autoregulatory circuit of human rpL3 expression requires hnRNP H1, NPM and KHSRP.

Russo A, Catillo M, Esposito D, Briata P, Pietropaolo C, Russo G.

Nucleic Acids Res. 2011 Sep 1;39(17):7576-85. doi: 10.1093/nar/gkr461. Epub 2011 Jun 25. Erratum in: Nucleic Acids Res. 2017 Dec 1;45(21):12600.

21.

KSRP, many functions for a single protein.

Briata P, Chen CY, Giovarelli M, Pasero M, Trabucchi M, Ramos A, Gherzi R.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1787-96. Review.

PMID:
21196264
22.

Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets.

Díaz-Moreno I, Hollingworth D, Kelly G, Martin S, García-Mayoral M, Briata P, Gherzi R, Ramos A.

Nucleic Acids Res. 2010 Aug;38(15):5193-205. doi: 10.1093/nar/gkq216. Epub 2010 Apr 12.

23.

KSRP promotes the maturation of a group of miRNA precursors.

Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG.

Adv Exp Med Biol. 2010;700:36-42.

24.

Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation.

Gherzi R, Trabucchi M, Ponassi M, Gallouzi IE, Rosenfeld MG, Briata P.

Cell Death Differ. 2010 Jun;17(6):975-83. doi: 10.1038/cdd.2009.194. Epub 2009 Dec 18.

25.

How to control miRNA maturation?

Trabucchi M, Briata P, Filipowicz W, Rosenfeld MG, Ramos A, Gherzi R.

RNA Biol. 2009 Nov-Dec;6(5):536-40. Review.

PMID:
19875945
26.

KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells.

Nechama M, Peng Y, Bell O, Briata P, Gherzi R, Schoenberg DR, Naveh-Many T.

BMC Cell Biol. 2009 Sep 23;10:70. doi: 10.1186/1471-2121-10-70.

27.

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.

Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG.

Nature. 2009 Jun 18;459(7249):1010-4. doi: 10.1038/nature08025. Epub 2009 May 20.

28.

LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages.

Ruggiero T, Trabucchi M, De Santa F, Zupo S, Harfe BD, McManus MT, Rosenfeld MG, Briata P, Gherzi R.

FASEB J. 2009 Sep;23(9):2898-908. doi: 10.1096/fj.09-131342. Epub 2009 May 7.

PMID:
19423639
29.

Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding.

Díaz-Moreno I, Hollingworth D, Frenkiel TA, Kelly G, Martin S, Howell S, García-Mayoral M, Gherzi R, Briata P, Ramos A.

Nat Struct Mol Biol. 2009 Mar;16(3):238-46. doi: 10.1038/nsmb.1558. Epub 2009 Feb 8.

30.

The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels.

Nechama M, Ben-Dov IZ, Briata P, Gherzi R, Naveh-Many T.

FASEB J. 2008 Oct;22(10):3458-68. doi: 10.1096/fj.08-107250. Epub 2008 Jun 26.

PMID:
18583400
31.

Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signaling.

Ruggiero T, Trabucchi M, Ponassi M, Corte G, Chen CY, al-Haj L, Khabar KS, Briata P, Gherzi R.

BMC Mol Biol. 2007 Apr 16;8:28.

32.
33.

p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts.

Briata P, Forcales SV, Ponassi M, Corte G, Chen CY, Karin M, Puri PL, Gherzi R.

Mol Cell. 2005 Dec 22;20(6):891-903.

34.

A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery.

Gherzi R, Lee KY, Briata P, Wegmüller D, Moroni C, Karin M, Chen CY.

Mol Cell. 2004 Jun 4;14(5):571-83.

35.

The Wnt/beta-catenin-->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs.

Briata P, Ilengo C, Corte G, Moroni C, Rosenfeld MG, Chen CY, Gherzi R.

Mol Cell. 2003 Nov;12(5):1201-11.

36.

Pituitary homeobox factor 1, a novel transcription factor in the adrenal regulating steroid 11beta-hydroxylase.

Hiroi N, Kino T, Bassett M, Rainey WE, Phung M, Abu-Asab M, Fojo T, Briata P, Chrousos GP, Bornstein SR.

Horm Metab Res. 2003 May;35(5):273-8.

PMID:
12915995
37.

Pitx genes during cardiovascular development.

Kioussi C, Briata P, Baek SH, Wynshaw-Boris A, Rose DW, Rosenfeld MG.

Cold Spring Harb Symp Quant Biol. 2002;67:81-7. No abstract available.

PMID:
12858527
38.

Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway.

Baek SH, Kioussi C, Briata P, Wang D, Nguyen HD, Ohgi KA, Glass CK, Wynshaw-Boris A, Rose DW, Rosenfeld MG.

Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3245-50. Epub 2003 Mar 10.

39.

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.

Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemler R, Glass CK, Wynshaw-Boris A, Rosenfeld MG.

Cell. 2002 Nov 27;111(5):673-85.

40.

Multistep signaling and transcriptional requirements for pituitary organogenesis in vivo.

Rosenfeld MG, Briata P, Dasen J, Gleiberman AS, Kioussi C, Lin C, O'Connell SM, Ryan A, Szeto DP, Treier M.

Recent Prog Horm Res. 2000;55:1-13; discussion 13-4. Review.

PMID:
11036930
41.

Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis.

Lin CR, Kioussi C, O'Connell S, Briata P, Szeto D, Liu F, Izpisúa-Belmonte JC, Rosenfeld MG.

Nature. 1999 Sep 16;401(6750):279-82.

PMID:
10499586
42.

OTX2 homeodomain protein binds a DNA element necessary for interphotoreceptor retinoid binding protein gene expression.

Bobola N, Briata P, Ilengo C, Rosatto N, Craft C, Corte G, Ravazzolo R.

Mech Dev. 1999 Apr;82(1-2):165-9.

43.

Binding properties of the human homeodomain protein OTX2 to a DNA target sequence.

Briata P, Ilengo C, Bobola N, Corte G.

FEBS Lett. 1999 Feb 19;445(1):160-4.

44.

EMX2 protein in the developing mouse brain and olfactory area.

Mallamaci A, Iannone R, Briata P, Pintonello L, Mercurio S, Boncinelli E, Corte G.

Mech Dev. 1998 Oct;77(2):165-72.

45.
46.

Implication of OTX2 in pigment epithelium determination and neural retina differentiation.

Bovolenta P, Mallamaci A, Briata P, Corte G, Boncinelli E.

J Neurosci. 1997 Jun 1;17(11):4243-52.

47.

The human homeodomain protein OTX2 binds to the human tenascin-C promoter and trans-represses its activity in transfected cells.

Gherzi R, Briata P, Boncinelli E, Ponassi M, Querzè G, Viti F, Corte G, Zardi L.

DNA Cell Biol. 1997 May;16(5):559-67.

PMID:
9174161
48.

Mapping of a potent transcriptional repression region of the human homeodomain protein EVX1.

Briata P, Ilengo C, Van DeWerken R, Corte G.

FEBS Lett. 1997 Feb 3;402(2-3):131-5.

49.

OTX2 homeoprotein in the developing central nervous system and migratory cells of the olfactory area.

Mallamaci A, Di Blas E, Briata P, Boncinelli E, Corte G.

Mech Dev. 1996 Aug;58(1-2):165-78.

50.

EMX1 homeoprotein is expressed in cell nuclei of the developing cerebral cortex and in the axons of the olfactory sensory neurons.

Briata P, Di Blas E, Gulisano M, Mallamaci A, Iannone R, Boncinelli E, Corte G.

Mech Dev. 1996 Jul;57(2):169-80.

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