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Items: 19


Negative modulation of suppressive HIV-specific regulatory T cells by IL-2 adjuvanted therapeutic vaccine.

Brezar V, Hani L, Surenaud M, Hubert A, Lacabaratz C, Lelièvre JD, Levy Y, Seddiki N.

PLoS Pathog. 2017 Jul 14;13(7):e1006489. doi: 10.1371/journal.ppat.1006489. eCollection 2017 Jul.


Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells.

Tu WJ, Hardy K, Sutton CR, McCuaig R, Li J, Dunn J, Tan A, Brezar V, Morris M, Denyer G, Lee SK, Turner SJ, Seddiki N, Smith C, Khanna R, Rao S.

Sci Rep. 2017 Mar 20;7:44825. doi: 10.1038/srep44825.


T-Regulatory Cells and Vaccination "Pay Attention and Do Not Neglect Them": Lessons from HIV and Cancer Vaccine Trials.

Brezar V, Godot V, Cheng L, Su L, Lévy Y, Seddiki N.

Vaccines (Basel). 2016 Sep 5;4(3). pii: E30. doi: 10.3390/vaccines4030030. Review.


Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation.

Li J, Hardy K, Phetsouphanh C, Tu WJ, Sutcliffe EL, McCuaig R, Sutton CR, Zafar A, Munier CM, Zaunders JJ, Xu Y, Theodoratos A, Tan A, Lim PS, Knaute T, Masch A, Zerweck J, Brezar V, Milburn PJ, Dunn J, Casarotto MG, Turner SJ, Seddiki N, Kelleher AD, Rao S.

J Cell Sci. 2016 Jun 15;129(12):2448-61. doi: 10.1242/jcs.181248. Epub 2016 May 5.


PKC-Theta in Regulatory and Effector T-cell Functions.

Brezar V, Tu WJ, Seddiki N.

Front Immunol. 2015 Oct 13;6:530. doi: 10.3389/fimmu.2015.00530. eCollection 2015. Review.


Decreased HIV-specific T-regulatory responses are associated with effective DC-vaccine induced immunity.

Brezar V, Ruffin N, Richert L, Surenaud M, Lacabaratz C, Palucka K, Thiébaut R, Banchereau J, Levy Y, Seddiki N.

PLoS Pathog. 2015 Mar 27;11(3):e1004752. doi: 10.1371/journal.ppat.1004752. eCollection 2015 Mar.


Low SAMHD1 expression following T-cell activation and proliferation renders CD4+ T cells susceptible to HIV-1.

Ruffin N, Brezar V, Ayinde D, Lefebvre C, Schulze Zur Wiesch J, van Lunzen J, Bockhorn M, Schwartz O, Hocini H, Lelievre JD, Banchereau J, Levy Y, Seddiki N.

AIDS. 2015 Mar 13;29(5):519-30. doi: 10.1097/QAD.0000000000000594.


Cell exhaustion in HIV-1 infection: role of suppressor cells.

Seddiki N, Brezar V, Draenert R.

Curr Opin HIV AIDS. 2014 Sep;9(5):452-8. doi: 10.1097/COH.0000000000000087. Review.


A highly relevant and efficient single step method for simultaneous depletion and isolation of human regulatory T cells in a clinical setting.

Brezar V, Ruffin N, Lévy Y, Seddiki N.

J Immunol Methods. 2014 Sep;411:70-5. doi: 10.1016/j.jim.2014.06.003. Epub 2014 Jun 10.


Role of miR-155 in the regulation of lymphocyte immune function and disease.

Seddiki N, Brezar V, Ruffin N, Lévy Y, Swaminathan S.

Immunology. 2014 May;142(1):32-8. doi: 10.1111/imm.12227. Review.


Insulin and type 1 diabetes: immune connections.

Culina S, Brezar V, Mallone R.

Eur J Endocrinol. 2013 Jan 17;168(2):R19-31. doi: 10.1530/EJE-12-0693. Print 2013 Feb. Review.


Short-term subcutaneous insulin treatment delays but does not prevent diabetes in NOD mice.

Brezar V, Culina S, Gagnerault MC, Mallone R.

Eur J Immunol. 2012 Jun;42(6):1553-61. doi: 10.1002/eji.201242394.


T cells recognizing a peptide contaminant undetectable by mass spectrometry.

Brezar V, Culina S, Østerbye T, Guillonneau F, Chiappetta G, Verdier Y, Vinh J, Wong FS, Buus S, Mallone R.

PLoS One. 2011;6(12):e28866. doi: 10.1371/journal.pone.0028866. Epub 2011 Dec 14.


Antibodies recognizing Mycobacterium avium paratuberculosis epitopes cross-react with the beta-cell antigen ZnT8 in Sardinian type 1 diabetic patients.

Masala S, Paccagnini D, Cossu D, Brezar V, Pacifico A, Ahmed N, Mallone R, Sechi LA.

PLoS One. 2011;6(10):e26931. doi: 10.1371/journal.pone.0026931. Epub 2011 Oct 27.


To B or not to B: (anti)bodies of evidence on the crime scene of type 1 diabetes?

Mallone R, Brezar V.

Diabetes. 2011 Aug;60(8):2020-2. doi: 10.2337/db11-0700. No abstract available.


T cell recognition of autoantigens in human type 1 diabetes: clinical perspectives.

Mallone R, Brezar V, Boitard C.

Clin Dev Immunol. 2011;2011:513210. doi: 10.1155/2011/513210. Epub 2011 Jul 19. Review.


Beyond the hormone: insulin as an autoimmune target in type 1 diabetes.

Brezar V, Carel JC, Boitard C, Mallone R.

Endocr Rev. 2011 Oct;32(5):623-69. doi: 10.1210/er.2011-0010. Epub 2011 Jun 23. Review.


Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay.

Diana J, Brezar V, Beaudoin L, Dalod M, Mellor A, Tafuri A, von Herrath M, Boitard C, Mallone R, Lehuen A.

J Exp Med. 2011 Apr 11;208(4):729-45. doi: 10.1084/jem.20101692. Epub 2011 Mar 28.


Serum-free culture medium and IL-7 costimulation increase the sensitivity of ELISpot detection.

Martinuzzi E, Scotto M, Enée E, Brezar V, Ribeil JA, van Endert P, Mallone R.

J Immunol Methods. 2008 Apr 20;333(1-2):61-70. doi: 10.1016/j.jim.2008.01.003. Epub 2008 Jan 29.

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