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Items: 1 to 50 of 65

1.

Purification and characterization of akr1b10 from human liver: role in carbonyl reduction of xenobiotics.

Martin HJ, Breyer-Pfaff U, Wsol V, Venz S, Block S, Maser E.

Drug Metab Dispos. 2006 Mar;34(3):464-70. Epub 2005 Dec 28.

PMID:
16381663
2.

Carbonyl reduction of naltrexone and dolasetron by oxidoreductases isolated from human liver cytosol.

Breyer-Pfaff U, Nill K.

J Pharm Pharmacol. 2004 Dec;56(12):1601-6.

PMID:
15563768
3.

The metabolic fate of amitriptyline, nortriptyline and amitriptylinoxide in man.

Breyer-Pfaff U.

Drug Metab Rev. 2004 Oct;36(3-4):723-46. Review.

PMID:
15554244
5.

Tertiary N-glucuronides of clozapine and its metabolite desmethylclozapine in patient urine.

Breyer-Pfaff U, Wachsmuth H.

Drug Metab Dispos. 2001 Oct;29(10):1343-8.

PMID:
11560879
6.

Isolation and identification of clozapine metabolites in patient urine.

Schaber G, Wiatr G, Wachsmuth H, Dachtler M, Albert K, Gaertner I, Breyer-Pfaff U.

Drug Metab Dispos. 2001 Jun;29(6):923-31.

PMID:
11353764
7.

Critical evaluation of the effect of valerian extract on sleep structure and sleep quality.

Giedke H, Breyer-Pfaff U.

Pharmacopsychiatry. 2000 Nov;33(6):239. No abstract available.

PMID:
11147934
9.
11.
12.

Norharman--is it an exclusively endogenous modulator of behavior?

Breyer-Pfaff U.

Pharmacopsychiatry. 1999 Jul;32(4):159-60. No abstract available.

PMID:
10505489
13.
14.

Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearance.

Schaber G, Stevens I, Gaertner HJ, Dietz K, Breyer-Pfaff U.

Br J Clin Pharmacol. 1998 Nov;46(5):453-9.

15.

Variability of diphenhydramine N-glucuronidation in healthy subjects.

Fischer D, Breyer-Pfaff U.

Eur J Drug Metab Pharmacokinet. 1997 Apr-Jun;22(2):151-4.

PMID:
9248784
16.
17.

[Amalgam--"etiology" of psychiatric disorders?].

Foerster K, Breyer-Pfaff U.

Versicherungsmedizin. 1996 Apr 1;48(2):62-4. German.

PMID:
8659057
18.

Elevated norharman plasma levels in alcoholic patients and controls resulting from tobacco smoking.

Breyer-Pfaff U, Wiatr G, Stevens I, Gaertner HJ, Mundle G, Mann K.

Life Sci. 1996;58(17):1425-32.

PMID:
8622568
19.
21.

Secretion of amitriptyline and metabolites into breast milk.

Breyer-Pfaff U, Nill K, Entenmann KN, Gaertner HJ.

Am J Psychiatry. 1995 May;152(5):812-3. No abstract available.

PMID:
7726331
22.

Renal clearance of pyridostigmine in myasthenic patients and volunteers under the influence of ranitidine and pirenzepine.

Eiermann B, Sommer N, Winne D, Schumm F, Maier U, Breyer-Pfaff U.

Xenobiotica. 1993 Nov;23(11):1263-75.

PMID:
8310710
23.

Enantioselective amitriptyline metabolism in patients phenotyped for two cytochrome P450 isozymes.

Breyer-Pfaff U, Pfandl B, Nill K, Nusser E, Monney C, Jonzier-Perey M, Baettig D, Baumann P.

Clin Pharmacol Ther. 1992 Oct;52(4):350-8.

PMID:
1424408
24.

Stereoselective inhibition of nortriptyline hydroxylation in man by quinidine.

Pfandl B, Mörike K, Winne D, Schareck W, Breyer-Pfaff U.

Xenobiotica. 1992 Jun;22(6):721-30.

PMID:
1441595
25.

Urinary metabolites of amitriptylinoxide and amitriptyline in single-dose experiments and during continuous therapy.

Becher B, Fischer W, Taneri Z, Scholz E, Müller WE, Breyer-Pfaff U.

Psychopharmacology (Berl). 1992;106(3):303-10.

PMID:
1570375
26.

Urinary dolichol--a doubtful marker of alcoholism.

Stetter F, Gaertner HJ, Wiatr G, Mann K, Breyer-Pfaff U.

Alcohol Clin Exp Res. 1991 Dec;15(6):938-41.

PMID:
1686372
27.

Quaternary N-glucuronides of 10-hydroxylated amitriptyline metabolites in human urine.

Breyer-Pfaff U, Becher B, Nusser E, Nill K, Baier-Weber B, Zaunbrecher D, Wachsmuth H, Prox A.

Xenobiotica. 1990 Jul;20(7):727-38.

PMID:
2238706
28.

Enantiomer analysis of E- and Z-10-hydroxyamitriptyline in human urine.

Nusser E, Nill K, Breyer-Pfaff U.

J Chromatogr. 1990 Jun 8;528(1):163-71.

PMID:
2384550
29.

Neuromuscular function and plasma drug levels in pyridostigmine treatment of myasthenia gravis.

Breyer-Pfaff U, Schmezer A, Maier U, Brinkmann A, Schumm F.

J Neurol Neurosurg Psychiatry. 1990 Jun;53(6):502-6.

30.

Validation of a therapeutic plasma level range in amitriptyline treatment of depression.

Breyer-Pfaff U, Giedke H, Gaertner HJ, Nill K.

J Clin Psychopharmacol. 1989 Apr;9(2):116-21.

PMID:
2723128
31.

Serum albumin stimulates serotonin uptake into human blood platelets.

Breyer-Pfaff U, Fauss C, Böhne HP.

Life Sci. 1989;44(18):1251-8.

PMID:
2716470
32.

Binding of tricyclic psychoactive drugs in plasma: contribution of individual proteins and drug interactions.

Breyer-Pfaff U, Brinkschulte M.

Prog Clin Biol Res. 1989;300:351-61. Review. No abstract available.

PMID:
2674970
33.

Non-response to antidepressants: risk factors and therapeutic possibilities.

Möller HJ, Kissling W, Baumann P, Breyer-Pfaff U, Delini-Stula A, Holsboer F, Jungkunz G, Kuhs H, Laux G, Müller WE.

Pharmacopsychiatry. 1988 Nov;21(6):285-7. No abstract available. Erratum in: Pharmacopsychiatry 1989 Mar;22(2):92. Baumann, W [corrected to Baumann, P].

PMID:
3244754
34.

Enantioselective formation and disposition of (E)- and (Z)-10-hydroxynortriptyline.

Nusser E, Nill K, Breyer-Pfaff U.

Drug Metab Dispos. 1988 May-Jun;16(3):509-11. No abstract available.

PMID:
2900750
35.

Glucuronides of hydroxylated metabolites of amitriptyline and nortriptyline isolated from rat bile.

Baier-Weber B, Prox A, Wachsmuth H, Breyer-Pfaff U.

Drug Metab Dispos. 1988 May-Jun;16(3):490-6.

PMID:
2900745
36.

Single-dose kinetics of the neuroleptic drug perazine in psychotic patients.

Breyer-Pfaff U, Nill K, Schied HW, Gaertner HJ, Giedke H.

Psychopharmacology (Berl). 1988;95(3):374-7.

PMID:
2901127
37.

Amitriptyline metabolites in human urine. Identification of phenols, dihydrodiols, glycols, and ketones.

Prox A, Breyer-Pfaff U.

Drug Metab Dispos. 1987 Nov-Dec;15(6):890-6.

PMID:
2893718
38.

Phenolic metabolites of amitriptyline and nortriptyline in rat bile.

Breyer-Pfaff U, Prox A, Wachsmuth H, Yao PP.

Drug Metab Dispos. 1987 Nov-Dec;15(6):882-9.

PMID:
2893717
39.

Autonomic nervous system differences as predictors of short-term outcome in schizophrenics.

Straube ER, Schied HW, Rein W, Breyer-Pfaff U.

Pharmacopsychiatry. 1987 May;20(3):105-10.

PMID:
2885864
40.

Amitriptyline and oxaprotiline in the treatment of hospitalized depressive patients. Clinical aspects, psychophysiology, and drug plasma levels.

Giedke H, Gaertner H, Breyer-Pfaff U, Rein W, Axmann D.

Eur Arch Psychiatry Neurol Sci. 1986;235(6):329-38.

PMID:
3527706
41.

Phenolic metabolites of chlorprothixene in man and dog.

Breyer-Pfaff U, Wiest E, Prox A, Wachsmuth H, Protiva M, Sindelár K, Friebolin H, Krauss D, Kunzelmann P.

Drug Metab Dispos. 1985 Jul-Aug;13(4):479-89.

PMID:
2863114
42.

Pyridostigmine kinetics in healthy subjects and patients with myasthenia gravis.

Breyer-Pfaff U, Maier U, Brinkmann AM, Schumm F.

Clin Pharmacol Ther. 1985 May;37(5):495-501.

PMID:
3987173
43.

Isolation and identification of hydroxylated maprotiline metabolites.

Breyer-Pfaff U, Kroeker M, Winkler T, Kriemler P.

Xenobiotica. 1985 Jan;15(1):57-66.

PMID:
3984384
44.
45.

[Biochemical, pharmacologic and psychophysiologic studies for the optimization of drug therapy in depressive illnesses].

Gaertner HJ, Giedke H, Breyer-Pfaff U.

Nervenarzt. 1984 Mar;55(3):133-6. German. No abstract available.

PMID:
6717696
46.
47.

Prediction and evaluation criteria in perazine therapy of acute schizophrenics. Pharmacokinetic data.

Breyer-Pfaff U, Brinkschulte M, Rein W, Schied HW, Straube E.

Pharmacopsychiatria. 1983 Sep;16(5):160-5.

PMID:
6140695
48.

Prediction and evaluation criteria in perazine therapy of acute schizophrenics: psychopathological results.

Schied HW, Rein W, Straube E, Jung H, Breyer-Pfaff U.

Pharmacopsychiatria. 1983 Sep;16(5):152-9.

PMID:
6140694
49.
50.

Response to maprotiline treatment in depressive patients relationship to urinary MHPG excretion and plasma drug level.

Gaertner HJ, Golfinopoulos G, Breyer-Pfaff U.

Pharmacopsychiatria. 1982 Sep;15(5):170-4.

PMID:
7178231

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