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Items: 1 to 50 of 60

1.

Human leucocyte antigen class I-redirected anti-tumour CD4+ T cells require a higher T cell receptor binding affinity for optimal activity than CD8+ T cells.

Tan MP, Dolton GM, Gerry AB, Brewer JE, Bennett AD, Pumphrey NJ, Jakobsen BK, Sewell AK.

Clin Exp Immunol. 2017 Jan;187(1):124-137. doi: 10.1111/cei.12828. Epub 2016 Nov 14.

2.

NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma.

Rapoport AP, Stadtmauer EA, Binder-Scholl GK, Goloubeva O, Vogl DT, Lacey SF, Badros AZ, Garfall A, Weiss B, Finklestein J, Kulikovskaya I, Sinha SK, Kronsberg S, Gupta M, Bond S, Melchiori L, Brewer JE, Bennett AD, Gerry AB, Pumphrey NJ, Williams D, Tayton-Martin HK, Ribeiro L, Holdich T, Yanovich S, Hardy N, Yared J, Kerr N, Philip S, Westphal S, Siegel DL, Levine BL, Jakobsen BK, Kalos M, June CH.

Nat Med. 2015 Aug;21(8):914-921. doi: 10.1038/nm.3910. Epub 2015 Jul 20.

3.

T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells.

Tan MP, Gerry AB, Brewer JE, Melchiori L, Bridgeman JS, Bennett AD, Pumphrey NJ, Jakobsen BK, Price DA, Ladell K, Sewell AK.

Clin Exp Immunol. 2015 May;180(2):255-70. doi: 10.1111/cei.12570.

4.

Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells.

Cameron BJ, Gerry AB, Dukes J, Harper JV, Kannan V, Bianchi FC, Grand F, Brewer JE, Gupta M, Plesa G, Bossi G, Vuidepot A, Powlesland AS, Legg A, Adams KJ, Bennett AD, Pumphrey NJ, Williams DD, Binder-Scholl G, Kulikovskaya I, Levine BL, Riley JL, Varela-Rohena A, Stadtmauer EA, Rapoport AP, Linette GP, June CH, Hassan NJ, Kalos M, Jakobsen BK.

Sci Transl Med. 2013 Aug 7;5(197):197ra103. doi: 10.1126/scitranslmed.3006034.

5.

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma.

Linette GP, Stadtmauer EA, Maus MV, Rapoport AP, Levine BL, Emery L, Litzky L, Bagg A, Carreno BM, Cimino PJ, Binder-Scholl GK, Smethurst DP, Gerry AB, Pumphrey NJ, Bennett AD, Brewer JE, Dukes J, Harper J, Tayton-Martin HK, Jakobsen BK, Hassan NJ, Kalos M, June CH.

Blood. 2013 Aug 8;122(6):863-71. doi: 10.1182/blood-2013-03-490565. Epub 2013 Jun 14.

6.

High affinity soluble ILT2 receptor: a potent inhibitor of CD8(+) T cell activation.

Moysey RK, Li Y, Paston SJ, Baston EE, Sami MS, Cameron BJ, Gavarret J, Todorov P, Vuidepot A, Dunn SM, Pumphrey NJ, Adams KJ, Yuan F, Dennis RE, Sutton DH, Johnson AD, Brewer JE, Ashfield R, Lissin NM, Jakobsen BK.

Protein Cell. 2010 Dec;1(12):1118-27. doi: 10.1007/s13238-010-0144-5. Epub 2011 Jan 8.

7.

Inhomogeneity and temporal effects in AutoPulse Assisted Prehospital International Resuscitation--an exception from consent trial terminated early.

Paradis NA, Young G, Lemeshow S, Brewer JE, Halperin HR.

Am J Emerg Med. 2010 May;28(4):391-8. doi: 10.1016/j.ajem.2010.02.002.

PMID:
20466215
8.

Medical device design process.

Gilman BL, Brewer JE, Kroll MW.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:5609-12. doi: 10.1109/IEMBS.2009.5333644.

PMID:
19964397
9.

Medium voltage therapy for preventing and treating asystole and PEA in ICDs.

Gilman BL, Brewer JE, Kroll K, Kroll MW.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:4623-5. doi: 10.1109/IEMBS.2009.5332679.

PMID:
19963853
10.

Coronary blood flow produced by muscle contractions induced by intracardiac electrical CPR during ventricular fibrillation.

Wang H, Tang W, Tsai MS, Sun S, Li Y, Gilman B, Kroll MW, Guan J, Brewer JE, Weil MH.

Pacing Clin Electrophysiol. 2009 Mar;32 Suppl 1:S223-7. doi: 10.1111/j.1540-8159.2008.02287.x.

PMID:
19250101
11.

Transthoracic application of electrical cardiopulmonary resuscitation for treatment of cardiac arrest.

Wang H, Brewer JE, Guan J, Gilman B, Sun S, Li Y, Castillo C, Kroll MW, Weil MH, Tang W.

Crit Care Med. 2008 Nov;36(11 Suppl):S458-66.

PMID:
20449911
12.

A randomized controlled feasibility trial comparing safety and effectiveness of prehospital pacing versus conventional treatment: 'PrePACE'.

Morrison LJ, Long J, Vermeulen M, Schwartz B, Sawadsky B, Frank J, Cameron B, Burgess R, Shield J, Bagley P, Mausz V, Brewer JE, Dorian P.

Resuscitation. 2008 Mar;76(3):341-9. Epub 2007 Oct 22.

PMID:
17933452
13.

Sensitivity and specificity of an automated external defibrillator algorithm designed for pediatric patients.

Atkins DL, Scott WA, Blaufox AD, Law IH, Dick M 2nd, Geheb F, Sobh J, Brewer JE.

Resuscitation. 2008 Feb;76(2):168-74. Epub 2007 Aug 31.

PMID:
17765384
14.

The HLA A*0201-restricted hTERT(540-548) peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor.

Purbhoo MA, Li Y, Sutton DH, Brewer JE, Gostick E, Bossi G, Laugel B, Moysey R, Baston E, Liddy N, Cameron B, Bennett AD, Ashfield R, Milicic A, Price DA, Classon BJ, Sewell AK, Jakobsen BK.

Mol Cancer Ther. 2007 Jul;6(7):2081-91.

15.

Comparison of rectilinear biphasic waveform with biphasic truncated exponential waveform in a pediatric defibrillation model.

Wang J, Tang W, Brewer JE, Freeman G, Chang YT, Weil MH.

Crit Care Med. 2007 Aug;35(8):1961-5.

PMID:
17581484
16.

Effects of biphasic waveforms on outcomes of cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrest.

Chang YT, Tang W, Wang J, Brewer JE, Freeman G, Sun S, Weil MH.

Crit Care Med. 2006 Dec;34(12):3024-8.

PMID:
17075369
17.

Quantifying and imaging NY-ESO-1/LAGE-1-derived epitopes on tumor cells using high affinity T cell receptors.

Purbhoo MA, Sutton DH, Brewer JE, Mullings RE, Hill ME, Mahon TM, Karbach J, J├Ąger E, Cameron BJ, Lissin N, Vyas P, Chen JL, Cerundolo V, Jakobsen BK.

J Immunol. 2006 Jun 15;176(12):7308-16.

18.

Reduced cardioversion thresholds for atrial fibrillation and flutter using the rectilinear biphasic waveform.

Niebauer MJ, Chung MK, Brewer JE, Tchou PJ.

J Interv Card Electrophysiol. 2005 Jul;13(2):145-50.

PMID:
16133842
19.

Out-of-hospital cardiac arrest rectilinear biphasic to monophasic damped sine defibrillation waveforms with advanced life support intervention trial (ORBIT).

Morrison LJ, Dorian P, Long J, Vermeulen M, Schwartz B, Sawadsky B, Frank J, Cameron B, Burgess R, Shield J, Bagley P, Mausz V, Brewer JE, Lerman BB; Steering Committee, Central Validation Committee, Safety and Efficacy Committee.

Resuscitation. 2005 Aug;66(2):149-57.

PMID:
15992986
20.

Cardiac safety of neuromuscular incapacitating defensive devices.

McDaniel WC, Stratbucker RA, Nerheim M, Brewer JE.

Pacing Clin Electrophysiol. 2005 Jan;28 Suppl 1:S284-7.

PMID:
15683517
21.

Rectilinear biphasic waveform defibrillation of out-of-hospital cardiac arrest.

Stothert JC, Hatcher TS, Gupton CL, Love JE, Brewer JE.

Prehosp Emerg Care. 2004 Oct-Dec;8(4):388-92.

PMID:
15625999
22.

High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy.

Huxley P, Sutton DH, Debnam P, Matthews IR, Brewer JE, Rose J, Trickett M, Williams DD, Andersen TB, Classon BJ.

Chem Biol. 2004 Dec;11(12):1651-8.

23.
24.

Multicenter study of principles-based waveforms for external defibrillation.

Bain AC, Swerdlow CD, Love CJ, Ellenbogen KA, Deering TF, Brewer JE, Augostini RS, Tchou PJ.

Ann Emerg Med. 2001 Jan;37(1):5-12.

PMID:
11145764
25.

Yield of postoperative fever evaluation.

Fanning J, Neuhoff RA, Brewer JE, Castaneda T, Marcotte MP, Jacobson RL.

Prim Care Update Ob Gyns. 1998 Jul 1;5(4):146.

PMID:
10838267
26.

External exponential biphasic versus monophasic shock waveform: efficacy in ventricular fibrillation of longer duration.

Yamanouchi Y, Brewer JE, Donohoo AM, Mowrey KA, Wilkoff BL, Tchou PJ.

Pacing Clin Electrophysiol. 1999 Oct;22(10):1481-7.

PMID:
10588150
27.

Fully discharging phases. A new approach to biphasic waveforms for external defibrillation.

Yamanouchi Y, Brewer JE, Olson KF, Mowrey KA, Mazgalev TN, Wilkoff BL, Tchou PJ.

Circulation. 1999 Aug 24;100(8):826-31.

PMID:
10458718
28.

Frequency and yield of postoperative fever evaluation.

Fanning J, Neuhoff RA, Brewer JE, Castaneda T, Marcotte MP, Jacobson RL.

Infect Dis Obstet Gynecol. 1998;6(6):252-5.

29.

Optimal small-capacitor biphasic waveform for external defibrillation: influence of phase-1 tilt and phase-2 voltage.

Yamanouchi Y, Brewer JE, Mowrey KA, Donohoo AM, Wilkoff BL, Tchou PJ.

Circulation. 1998 Dec 1;98(22):2487-93.

PMID:
9832496
30.

Effects of respiration phase on ventricular defibrillation threshold in a hot can electrode system.

Yamanouchi Y, Mowrey KA, Kroll MW, Brewer JE, Donohoo AM, Niebauer MJ, Wilkoff BL, Tchou PJ.

Pacing Clin Electrophysiol. 1998 Jun;21(6):1216-24.

PMID:
9633063
31.

Effects of polarity on defibrillation thresholds using a biphasic waveform in a hot can electrode system.

Yamanouchi Y, Mowrey KA, Nadzam GR, Hills DG, Kroll MW, Brewer JE, Donohoo AM, Wilkoff BL, Tchou PJ.

Pacing Clin Electrophysiol. 1997 Dec;20(12 Pt 1):2911-6.

PMID:
9455750
32.
33.

Alarming defibrillator headlines.

Gilman BL, Brewer JE, Klein TK.

Ann Emerg Med. 1997 Dec;30(6):836-7. No abstract available.

PMID:
9398789
34.

Optimized first phase tilt in "parallel-series" biphasic waveform.

Yamanouchi Y, Mowrey KA, Kroll MW, Brewer JE, Donohoo AM, Wilkoff BL, Tchou PJ.

J Cardiovasc Electrophysiol. 1997 Jun;8(6):649-57.

PMID:
9209966
35.

Sawtooth first phase biphasic defibrillation waveform: a comparison with standard waveform in clinical devices.

Yamanouchi Y, Brewer JE, Mowrey KA, Kroll MW, Donohoo AM, Wilkoff BL, Tchou PJ.

J Cardiovasc Electrophysiol. 1997 May;8(5):517-28.

PMID:
9160228
36.

Automated external defibrillators: design considerations.

Kroll MW, Brewer JE.

New Horiz. 1997 May;5(2):128-36. Review.

PMID:
9153042
37.

Dual level sensing significantly improves automatic threshold control for R wave sensing in implantable defibrillators. The Angeion Corporation.

Brewer JE, Perttu JS, Kroll MW, Donohoo AM.

Pacing Clin Electrophysiol. 1996 Dec;19(12 Pt 1):2051-9.

PMID:
8994943
38.
39.

Large change in voltage at phase reversal improves biphasic defibrillation thresholds. Parallel-series mode switching.

Yamanouchi Y, Mowrey KA, Nadzam GR, Hills DG, Kroll MW, Brewer JE, Donohoo AM, Wilkoff BL, Tchou PJ.

Circulation. 1996 Oct 1;94(7):1768-73.

PMID:
8840873
40.

Defibrillation thresholds are lower with smaller storage capacitors.

Leonelli FM, Kroll MW, Brewer JE.

Pacing Clin Electrophysiol. 1995 Sep;18(9 Pt 1):1661-5.

PMID:
7491309
41.

Woven wire patches are superior to solid disks for subcutaneous electrodes: implications for active can defibrillation.

Leonelli FM, Wright H, Brewer JE, Adams TP, Kroll MW.

Pacing Clin Electrophysiol. 1995 Jan;18(1 Pt 2):225-8.

PMID:
7724404
42.

Low voltage shocks have a significantly higher tilt of the internal electric field than do high voltage shocks.

Brewer JE, Tvedt MA, Adams TP, Kroll MW.

Pacing Clin Electrophysiol. 1995 Jan;18(1 Pt 2):214.

PMID:
7724402
43.

Smaller capacitors improve the biphasic waveform.

Rist K, Tchou PJ, Mowrey K, Kroll MW, Brewer JE.

J Cardiovasc Electrophysiol. 1994 Sep;5(9):771-6.

PMID:
7827716
44.

Protein binding of tirilazad (U-74006) in human, Sprague-Dawley rat, beagle dog and cynomolgus monkey serum.

Bombardt PA, Brewer JE, Johnson MG.

J Pharmacol Exp Ther. 1994 Apr;269(1):145-50.

PMID:
8169818
45.

A phase I clinical and pharmacokinetic study of the oral and the oral/intravenous administration of menogaril.

Weiss GR, Brown TD, Kuhn JG, Von Hoff DD, Earhart RH, Adams WJ, Brewer JE, Hosley JD, Kasunic DA.

Invest New Drugs. 1993 Feb;11(1):17-27.

PMID:
8349432
46.

Simple, rapid and sensitive high-performance liquid chromatographic procedure for the quantitation of itazigrel in human plasma or serum.

Bombardt PA, Brewer JE, Thomas RC Jr, Koets MD.

J Chromatogr. 1990 Apr 27;527(1):233-7. No abstract available.

PMID:
2365787
47.

HPLC and flow cytometric analyses of uptake of adriamycin and menogaril by monolayers and multicell spheroids.

Bichay TJ, Adams EG, Inch WR, Adams WJ, Brewer JE, Bhuyan BK.

Sel Cancer Ther. 1990 Winter;6(4):153-66.

PMID:
2151298
48.

Pharmacokinetics and systemic bioavailability of menogaril, an anthracycline antitumor agent, in the mouse, dog, and monkey.

Adams WJ, McGovren JP, Dalm EA, Brewer JE, Hosley JD.

Cancer Res. 1989 Nov 15;49(22):6328-36.

49.

Phase I study of intravenous menogaril administered intermittently.

Dodion P, Sessa C, Joss R, Crespeigne N, Willems Y, Kitt M, Abrams J, Finet C, Brewer JE, Adams WJ, et al.

J Clin Oncol. 1986 May;4(5):767-74.

PMID:
2939203
50.

Normal-phase liquid chromatographic determination of alprazolam in human serum.

Adams WJ, Bombardt PA, Brewer JE.

Anal Chem. 1984 Aug;56(9):1590-4. No abstract available.

PMID:
6486443

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