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Items: 1 to 50 of 145

1.

Purple Urine Bag Syndrome in a Patient with an Ileal Conduit and Clostridium Difficile Infection.

Sadler C, Brewer CF, Khan T, Murch N.

Acute Med. 2019;18(4):251-254. Review.

PMID:
31912058
2.

Effects of Genetically Determined Iron Status on Risk of Venous Thromboembolism and Carotid Atherosclerotic Disease: A Mendelian Randomization Study.

Gill D, Brewer CF, Monori G, Trégouët DA, Franceschini N, Giambartolomei C; INVENT Consortium, Tzoulaki I, Dehghan A.

J Am Heart Assoc. 2019 Aug 6;8(15):e012994. doi: 10.1161/JAHA.119.012994. Epub 2019 Jul 16.

3.

Reducing inappropriately suspended VTE prophylaxis through a multidisciplinary shared learning programme and electronic prompting.

Brewer CF, Ip D, Drasar E, Aghakhani P.

BMJ Open Qual. 2019 Mar 1;8(1):e000474. doi: 10.1136/bmjoq-2018-000474. eCollection 2019.

4.

Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate-carbohydrate interactions.

Sletmoen M, Gerken TA, Stokke BT, Burchell J, Brewer CF.

Glycobiology. 2018 Jul 1;28(7):437-442. doi: 10.1093/glycob/cwy032. Review.

5.

Age at menarche and adult body mass index: a Mendelian randomization study.

Gill D, Brewer CF, Del Greco M F, Sivakumaran P, Bowden J, Sheehan NA, Minelli C.

Int J Obes (Lond). 2018 Sep;42(9):1574-1581. doi: 10.1038/s41366-018-0048-7. Epub 2018 Feb 26.

6.

Interactions of mucins with the Tn or Sialyl Tn cancer antigens including MUC1 are due to GalNAc-GalNAc interactions.

Haugstad KE, Hadjialirezaei S, Stokke BT, Brewer CF, Gerken TA, Burchell J, Picco G, Sletmoen M.

Glycobiology. 2016 Dec;26(12):1338-1350. Epub 2016 Jun 9.

7.

Measuring Multivalent Binding Interactions by Isothermal Titration Calorimetry.

Dam TK, Talaga ML, Fan N, Brewer CF.

Methods Enzymol. 2016;567:71-95. doi: 10.1016/bs.mie.2015.08.013. Epub 2015 Sep 8.

PMID:
26794351
8.

Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen.

Haugstad KE, Stokke BT, Brewer CF, Gerken TA, Sletmoen M.

Glycobiology. 2015 May;25(5):524-34. doi: 10.1093/glycob/cwu183. Epub 2014 Dec 19.

9.

Probing lectin-mucin interactions by isothermal titration microcalorimetry.

Dam TK, Brewer CF.

Methods Mol Biol. 2015;1207:75-90. doi: 10.1007/978-1-4939-1396-1_5.

PMID:
25253134
10.

Density-dependent lectin-glycan interactions as a paradigm for conditional regulation by posttranslational modifications.

Dennis JW, Brewer CF.

Mol Cell Proteomics. 2013 Apr;12(4):913-20. doi: 10.1074/mcp.R112.026989. Epub 2013 Feb 1.

11.

Enhanced self-association of mucins possessing the T and Tn carbohydrate cancer antigens at the single-molecule level.

Haugstad KE, Gerken TA, Stokke BT, Dam TK, Brewer CF, Sletmoen M.

Biomacromolecules. 2012 May 14;13(5):1400-9. doi: 10.1021/bm300135h. Epub 2012 Apr 3.

12.

Fine specificities of two lectins from Cymbosema roseum seeds: a lectin specific for high-mannose oligosaccharides and a lectin specific for blood group H type II trisaccharide.

Dam TK, Cavada BS, Nagano CS, Rocha BA, Benevides RG, Nascimento KS, de Sousa LA, Oscarson S, Brewer CF.

Glycobiology. 2011 Jul;21(7):925-33. doi: 10.1093/glycob/cwr025. Epub 2011 Mar 15.

PMID:
21406562
13.

Maintenance of cell surface glycan density by lectin-glycan interactions: a homeostatic and innate immune regulatory mechanism.

Dam TK, Brewer CF.

Glycobiology. 2010 Sep;20(9):1061-4. doi: 10.1093/glycob/cwq084. Epub 2010 Jun 14. Review. No abstract available. Erratum in: Glycobiology. 2012 Apr;22(4):585. Brewer, Fred C [corrected to Brewer, C Fred].

PMID:
20548106
14.

Multivalent lectin-carbohydrate interactions energetics and mechanisms of binding.

Dam TK, Brewer CF.

Adv Carbohydr Chem Biochem. 2010;63:139-64. doi: 10.1016/S0065-2318(10)63005-3. Review.

PMID:
20381706
15.

Lectins as pattern recognition molecules: the effects of epitope density in innate immunity.

Dam TK, Brewer CF.

Glycobiology. 2010 Mar;20(3):270-9. doi: 10.1093/glycob/cwp186. Epub 2009 Nov 24. Review.

PMID:
19939826
16.

Single-molecule pair studies of the interactions of the alpha-GalNAc (Tn-antigen) form of porcine submaxillary mucin with soybean agglutinin.

Sletmoen M, Dam TK, Gerken TA, Stokke BT, Brewer CF.

Biopolymers. 2009 Sep;91(9):719-28. doi: 10.1002/bip.21213.

17.

Thermodynamics of multivalent carbohydrate-lectin cross-linking interactions: importance of entropy in the bind and jump mechanism.

Dam TK, Gerken TA, Brewer CF.

Biochemistry. 2009 May 12;48(18):3822-7. doi: 10.1021/bi9002919.

18.

Phosphorylated human lectin galectin-3: analysis of ligand binding by histochemical monitoring of normal/malignant squamous epithelia and by isothermal titration calorimetry.

Szabo P, Dam TK, Smetana K Jr, Dvoránková B, Kübler D, Brewer CF, Gabius HJ.

Anat Histol Embryol. 2009 Feb;38(1):68-75. doi: 10.1111/j.1439-0264.2008.00899.x. Epub 2008 Oct 18.

PMID:
18983621
19.

Isothermal titration calorimetry reveals differential binding thermodynamics of variable region-identical antibodies differing in constant region for a univalent ligand.

Dam TK, Torres M, Brewer CF, Casadevall A.

J Biol Chem. 2008 Nov 14;283(46):31366-70. doi: 10.1074/jbc.M806473200. Epub 2008 Sep 19.

20.

Effects of clustered epitopes in multivalent ligand-receptor interactions.

Dam TK, Brewer CF.

Biochemistry. 2008 Aug 19;47(33):8470-6. doi: 10.1021/bi801208b. Epub 2008 Jul 25.

PMID:
18652478
21.

Phosphorylated human galectin-3: facile large-scale preparation of active lectin and detection of structural changes by CD spectroscopy.

Kübler D, Hung CW, Dam TK, Kopitz J, André S, Kaltner H, Lohr M, Manning JC, He L, Wang H, Middelberg A, Brewer CF, Reed J, Lehmann WD, Gabius HJ.

Biochim Biophys Acta. 2008 Apr;1780(4):716-22. doi: 10.1016/j.bbagen.2008.01.018. Epub 2008 Feb 12.

PMID:
18302943
22.

Binding studies of alpha-GalNAc-specific lectins to the alpha-GalNAc (Tn-antigen) form of porcine submaxillary mucin and its smaller fragments.

Dam TK, Gerken TA, Cavada BS, Nascimento KS, Moura TR, Brewer CF.

J Biol Chem. 2007 Sep 21;282(38):28256-63. Epub 2007 Jul 25.

23.

Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death.

Stillman BN, Hsu DK, Pang M, Brewer CF, Johnson P, Liu FT, Baum LG.

J Immunol. 2006 Jan 15;176(2):778-89.

24.

Galectins bind to the multivalent glycoprotein asialofetuin with enhanced affinities and a gradient of decreasing binding constants.

Dam TK, Gabius HJ, André S, Kaltner H, Lensch M, Brewer CF.

Biochemistry. 2005 Sep 20;44(37):12564-71.

PMID:
16156668
25.

Thermodynamic, kinetic, and electron microscopy studies of concanavalin A and Dioclea grandiflora lectin cross-linked with synthetic divalent carbohydrates.

Dam TK, Oscarson S, Roy R, Das SK, Pagé D, Macaluso F, Brewer CF.

J Biol Chem. 2005 Mar 11;280(10):8640-6. Epub 2005 Jan 4.

26.
27.

Thermodynamic binding studies of bivalent oligosaccharides to galectin-1, galectin-3, and the carbohydrate recognition domain of galectin-3.

Ahmad N, Gabius HJ, Sabesan S, Oscarson S, Brewer CF.

Glycobiology. 2004 Sep;14(9):817-25. Epub 2004 May 17.

PMID:
15148296
28.

Multivalent protein-carbohydrate interactions: isothermal titration microcalorimetry studies.

Dam TK, Brewer CF.

Methods Enzymol. 2004;379:107-28. No abstract available.

PMID:
15051354
29.

Thermodynamic binding studies of galectin-1, -3 and -7.

Brewer CF.

Glycoconj J. 2002;19(7-9):459-65. Review.

PMID:
14758069
30.

Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes.

Ahmad N, Gabius HJ, André S, Kaltner H, Sabesan S, Roy R, Liu B, Macaluso F, Brewer CF.

J Biol Chem. 2004 Mar 19;279(12):10841-7. Epub 2003 Dec 12.

31.

Lectin cross-linking interactions with multivalent carbohydrates.

Brewer CF.

Adv Exp Med Biol. 2001;491:17-25.

PMID:
14533787
32.

Carbohydrate-lectin cross-linking interactions: structural, thermodynamic, and biological studies.

Dam TK, Brewer CF.

Methods Enzymol. 2003;362:455-86. No abstract available.

PMID:
12968382
33.

Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions.

Brewer CF, Miceli MC, Baum LG.

Curr Opin Struct Biol. 2002 Oct;12(5):616-23. Review.

PMID:
12464313
34.
35.

Thermodynamic studies of lectin-carbohydrate interactions by isothermal titration calorimetry.

Dam TK, Brewer CF.

Chem Rev. 2002 Feb;102(2):387-429. Review. No abstract available.

PMID:
11841248
37.
38.

Directing the immune response to carbohydrate antigens.

Cunto-Amesty G, Dam TK, Luo P, Monzavi-Karbassi B, Brewer CF, Van Cott TC, Kieber-Emmons T.

J Biol Chem. 2001 Aug 10;276(32):30490-8. Epub 2001 May 30. Erratum in: J Biol Chem 2001 Nov 2;276(44):41526.

39.

Multivalent protein-carbohydrate interactions. A new paradigm for supermolecular assembly and signal transduction.

Sacchettini JC, Baum LG, Brewer CF.

Biochemistry. 2001 Mar 13;40(10):3009-15. Review.

PMID:
11258914
40.

Synthesis of "sugar-rods" with phytohemagglutinin cross-linking properties by using the palladium-catalyzed Sonogashira reaction

Roy R, Das SK, Santoyo-Gonzalez F, Hernandez-Mateo F, Dam TK, Brewer CF.

Chemistry. 2000 May 15;6(10):1757-62.

PMID:
10845633
41.
42.

Thermodynamic binding studies of lectins from the diocleinae subtribe to deoxy analogs of the core trimannoside of asparagine-linked oligosaccharides.

Dam TK, Cavada BS, Grangeiro TB, Santos CF, Ceccatto VM, de Sousa FA, Oscarson S, Brewer CF.

J Biol Chem. 2000 May 26;275(21):16119-26.

43.

Demonstration of a conserved histidine and two water ligands at the Mn2+ site in Diocleinae lectins by pulsed EPR spectroscopy.

Lee HC, Goroncy AK, Peisach J, Cavada BS, Grangeiro TB, Ramos MV, Sampaio AH, Dam TK, Brewer CF.

Biochemistry. 2000 Mar 7;39(9):2340-6.

PMID:
10694401
44.
46.

Crystal structure of the lectin from Dioclea grandiflora complexed with core trimannoside of asparagine-linked carbohydrates.

Rozwarski DA, Swami BM, Brewer CF, Sacchettini JC.

J Biol Chem. 1998 Dec 4;273(49):32818-25.

48.
49.

X-ray crystallographic studies of unique cross-linked lattices between four isomeric biantennary oligosaccharides and soybean agglutinin.

Olsen LR, Dessen A, Gupta D, Sabesan S, Sacchettini JC, Brewer CF.

Biochemistry. 1997 Dec 9;36(49):15073-80.

PMID:
9398234

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