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Items: 1 to 50 of 113

1.

Degradation and in vivo evaluation of polycaprolactone, poly(ε-caprolactone-co-L-lactide), and poly-L-lactic acid as scaffold sealant polymers for murine tissue-engineered vascular grafts.

Agarwal R, Blum KM, Musgrave A, Onwuka EA, Yi T, Reinhardt JW, A Best C, Breuer CK.

Regen Med. 2019 Jul;14(7):627-637. doi: 10.2217/rme-2018-0069. Epub 2019 Jul 25.

PMID:
31342857
2.

Optimization of Tissue-Engineered Vascular Graft Design Using Computational Modeling.

Szafron JM, Ramachandra AB, Breuer CK, Marsden AL, Humphrey JD.

Tissue Eng Part C Methods. 2019 Oct;25(10):561-570. doi: 10.1089/ten.TEC.2019.0086. Epub 2019 Sep 3.

PMID:
31218941
3.

Differential outcomes of venous and arterial tissue engineered vascular grafts highlight the importance of coupling long-term implantation studies with computational modeling.

Best CA, Szafron JM, Rocco KA, Zbinden J, Dean EW, Maxfield MW, Kurobe H, Tara S, Bagi PS, Udelsman BV, Khosravi R, Yi T, Shinoka T, Humphrey JD, Breuer CK.

Acta Biomater. 2019 Aug;94:183-194. doi: 10.1016/j.actbio.2019.05.063. Epub 2019 Jun 12.

PMID:
31200116
4.

Early natural history of neotissue formation in tissue-engineered vascular grafts in a murine model.

Reinhardt JW, Rosado JDR, Barker JC, Lee YU, Best CA, Yi T, Zeng Q, Partida-Sanchez S, Shinoka T, Breuer CK.

Regen Med. 2019 May;14(5):389-408. doi: 10.2217/rme-2018-0133. Epub 2019 Jun 10.

PMID:
31180275
5.

Factors Influencing Poor Outcomes in Synthetic Tissue-Engineered Tracheal Replacement.

Pepper V, Best CA, Buckley K, Schwartz C, Onwuka E, King N, White A, Dharmadhikari S, Reynolds SD, Johnson J, Grischkan J, Breuer CK, Chiang T.

Otolaryngol Head Neck Surg. 2019 Sep;161(3):458-467. doi: 10.1177/0194599819844754. Epub 2019 Apr 30.

PMID:
31035858
6.

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model.

Wiet MG, Dharmadhikari S, White A, Reynolds SD, Johnson J, Breuer CK, Chiang T.

J Vis Exp. 2019 Apr 1;(146). doi: 10.3791/59173.

PMID:
30985752
7.

Mouse Model of Tracheal Replacement With Electrospun Nanofiber Scaffolds.

Dharmadhikari S, Best CA, King N, Henderson M, Johnson J, Breuer CK, Chiang T.

Ann Otol Rhinol Laryngol. 2019 May;128(5):391-400. doi: 10.1177/0003489419826134. Epub 2019 Jan 30.

8.

Implantation of VEGF-functionalized cell-free vascular grafts: regenerative and immunological response.

Smith RJ Jr, Yi T, Nasiri B, Breuer CK, Andreadis ST.

FASEB J. 2019 Apr;33(4):5089-5100. doi: 10.1096/fj.201801856R. Epub 2019 Jan 10.

PMID:
30629890
9.

Clinical validation and reproducibility of endoscopic airway measurement in pediatric aerodigestive evaluation.

Francom CR, Best CA, Eaton RG, Pepper V, Onwuka AJ, Breuer CK, Merz Lind MN, Grischkan JM, Chiang T.

Int J Pediatr Otorhinolaryngol. 2019 Jan;116:65-69. doi: 10.1016/j.ijporl.2018.10.004. Epub 2018 Oct 11.

PMID:
30554710
10.

Immuno-driven and Mechano-mediated Neotissue Formation in Tissue Engineered Vascular Grafts.

Szafron JM, Khosravi R, Reinhardt J, Best CA, Bersi MR, Yi T, Breuer CK, Humphrey JD.

Ann Biomed Eng. 2018 Nov;46(11):1938-1950. doi: 10.1007/s10439-018-2086-7. Epub 2018 Jul 9.

PMID:
29987541
11.

Magnetic Resonance Imaging of Shear Stress and Wall Thickness in Tissue-Engineered Vascular Grafts.

Stacy MR, Best CA, Maxfield MW, Qiu M, Naito Y, Kurobe H, Mahler N, Rocco KA, Sinusas AJ, Shinoka T, Sampath S, Breuer CK.

Tissue Eng Part C Methods. 2018 Aug;24(8):465-473. doi: 10.1089/ten.TEC.2018.0144. Epub 2018 Jul 31.

12.

Angiotensin II receptor I blockade prevents stenosis of tissue engineered vascular grafts.

Ruiz-Rosado JD, Lee YU, Mahler N, Yi T, Robledo-Avila F, Martinez-Saucedo D, Lee AY, Shoji T, Heuer E, Yates AR, Pober JS, Shinoka T, Partida-Sanchez S, Breuer CK.

FASEB J. 2018 Jun 15:fj201800458. doi: 10.1096/fj.201800458. [Epub ahead of print]

PMID:
29906242
13.

Bone marrow-derived mononuclear cell seeded bioresorbable vascular graft improves acute graft patency by inhibiting thrombus formation via platelet adhesion.

Miyachi H, Reinhardt JW, Otsuru S, Tara S, Nakayama H, Yi T, Lee YU, Miyamoto S, Shoji T, Sugiura T, Breuer CK, Shinoka T.

Int J Cardiol. 2018 Sep 1;266:61-66. doi: 10.1016/j.ijcard.2018.01.059.

14.

Oversized Biodegradable Arterial Grafts Promote Enhanced Neointimal Tissue Formation.

Best C, Fukunishi T, Drews J, Khosravi R, Hor K, Mahler N, Yi T, Humphrey JD, Johnson J, Breuer CK, Hibino N.

Tissue Eng Part A. 2018 Aug;24(15-16):1251-1261. doi: 10.1089/ten.TEA.2017.0483. Epub 2018 May 10.

15.

Tissue-engineered Vascular Grafts in Children With Congenital Heart Disease: Intermediate Term Follow-up.

Sugiura T, Matsumura G, Miyamoto S, Miyachi H, Breuer CK, Shinoka T.

Semin Thorac Cardiovasc Surg. 2018 Summer;30(2):175-179. doi: 10.1053/j.semtcvs.2018.02.002. Epub 2018 Feb 7.

16.

Tissue-Engineered Heart Valves: A Call for Mechanistic Studies.

Blum KM, Drews JD, Breuer CK.

Tissue Eng Part B Rev. 2018 Jun;24(3):240-253. doi: 10.1089/ten.TEB.2017.0425. Epub 2018 Feb 13.

17.

Designing a tissue-engineered tracheal scaffold for preclinical evaluation.

Best CA, Pepper VK, Ohst D, Bodnyk K, Heuer E, Onwuka EA, King N, Strouse R, Grischkan J, Breuer CK, Johnson J, Chiang T.

Int J Pediatr Otorhinolaryngol. 2018 Jan;104:155-160. doi: 10.1016/j.ijporl.2017.10.036. Epub 2017 Nov 22.

18.

Novel application and serial evaluation of tissue-engineered portal vein grafts in a murine model.

Maxfield MW, Stacy MR, Kurobe H, Tara S, Yi T, Cleary MA, Zhuang ZW, Rodriguez-Davalos MI, Emre SH, Iwakiri Y, Shinoka T, Breuer CK.

Regen Med. 2017 Dec;12(8):929-938. doi: 10.2217/rme-2017-0021. Epub 2017 Dec 7.

19.

Stress Analysis-Driven Design of Bilayered Scaffolds for Tissue-Engineered Vascular Grafts.

Szafron JM, Breuer CK, Wang Y, Humphrey JD.

J Biomech Eng. 2017 Dec 1;139(12). doi: 10.1115/1.4037856.

20.

Role of Bone Marrow Mononuclear Cell Seeding for Nanofiber Vascular Grafts.

Fukunishi T, Best CA, Ong CS, Groehl T, Reinhardt J, Yi T, Miyachi H, Zhang H, Shinoka T, Breuer CK, Johnson J, Hibino N.

Tissue Eng Part A. 2018 Jan;24(1-2):135-144. doi: 10.1089/ten.TEA.2017.0044. Epub 2017 Jun 13.

21.

Endoscopic management of tissue-engineered tracheal graft stenosis in an ovine model.

Pepper VK, Onwuka EA, Best CA, King N, Heuer E, Johnson J, Breuer CK, Grischkan JM, Chiang T.

Laryngoscope. 2017 Oct;127(10):2219-2224. doi: 10.1002/lary.26504. Epub 2017 Mar 27.

22.

Intravascular Ultrasound Characterization of a Tissue-Engineered Vascular Graft in an Ovine Model.

Pepper VK, Clark ES, Best CA, Onwuka EA, Sugiura T, Heuer ED, Moko LE, Miyamoto S, Miyachi H, Berman DP, Cheatham SL, Chisolm JL, Shinoka T, Breuer CK, Cheatham JP.

J Cardiovasc Transl Res. 2017 Apr;10(2):128-138. doi: 10.1007/s12265-016-9725-x. Epub 2017 Jan 17.

23.

Tropoelastin inhibits intimal hyperplasia of mouse bioresorbable arterial vascular grafts.

Sugiura T, Agarwal R, Tara S, Yi T, Lee YU, Breuer CK, Weiss AS, Shinoka T.

Acta Biomater. 2017 Apr 1;52:74-80. doi: 10.1016/j.actbio.2016.12.044. Epub 2016 Dec 23.

24.

Preclinical study of patient-specific cell-free nanofiber tissue-engineered vascular grafts using 3-dimensional printing in a sheep model.

Fukunishi T, Best CA, Sugiura T, Opfermann J, Ong CS, Shinoka T, Breuer CK, Krieger A, Johnson J, Hibino N.

J Thorac Cardiovasc Surg. 2017 Apr;153(4):924-932. doi: 10.1016/j.jtcvs.2016.10.066. Epub 2016 Nov 14.

26.

Objective characterization of airway dimensions using image processing.

Pepper VK, Francom C, Best CA, Onwuka E, King N, Heuer E, Mahler N, Grischkan J, Breuer CK, Chiang T.

Int J Pediatr Otorhinolaryngol. 2016 Dec;91:108-112. doi: 10.1016/j.ijporl.2016.10.004. Epub 2016 Oct 6.

27.

Fast-degrading bioresorbable arterial vascular graft with high cellular infiltration inhibits calcification of the graft.

Sugiura T, Tara S, Nakayama H, Yi T, Lee YU, Shoji T, Breuer CK, Shinoka T.

J Vasc Surg. 2017 Jul;66(1):243-250. doi: 10.1016/j.jvs.2016.05.096. Epub 2016 Sep 26.

28.

Impaired von Willebrand factor adhesion and platelet response in thrombospondin-2 knockout mice.

Kristofik N, Calabro NE, Tian W, Meng A, MacLauchlan S, Wang Y, Breuer CK, Tellides G, Niklason LE, Kyriakides TR.

Blood. 2016 Sep 22;128(12):1642-50. doi: 10.1182/blood-2016-03-702845. Epub 2016 Jul 28.

29.

Tissue-Engineered Small Diameter Arterial Vascular Grafts from Cell-Free Nanofiber PCL/Chitosan Scaffolds in a Sheep Model.

Fukunishi T, Best CA, Sugiura T, Shoji T, Yi T, Udelsman B, Ohst D, Ong CS, Zhang H, Shinoka T, Breuer CK, Johnson J, Hibino N.

PLoS One. 2016 Jul 28;11(7):e0158555. doi: 10.1371/journal.pone.0158555. eCollection 2016.

30.

Clinical Translation of Tissue Engineered Trachea Grafts.

Chiang T, Pepper V, Best C, Onwuka E, Breuer CK.

Ann Otol Rhinol Laryngol. 2016 Nov;125(11):873-885. Epub 2016 Jul 12. Review.

31.

Pilot Mouse Study of 1 mm Inner Diameter (ID) Vascular Graft Using Electrospun Poly(ester urea) Nanofibers.

Gao Y, Yi T, Shinoka T, Lee YU, Reneker DH, Breuer CK, Becker ML.

Adv Healthc Mater. 2016 Sep;5(18):2427-36. doi: 10.1002/adhm.201600400. Epub 2016 Jul 8.

32.

Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines.

Daley GQ, Hyun I, Apperley JF, Barker RA, Benvenisty N, Bredenoord AL, Breuer CK, Caulfield T, Cedars MI, Frey-Vasconcells J, Heslop HE, Jin Y, Lee RT, McCabe C, Munsie M, Murry CE, Piantadosi S, Rao M, Rooke HM, Sipp D, Studer L, Sugarman J, Takahashi M, Zimmerman M, Kimmelman J.

Stem Cell Reports. 2016 Jun 14;6(6):787-797. doi: 10.1016/j.stemcr.2016.05.001. Epub 2016 May 12.

33.

Novel Bioresorbable Vascular Graft With Sponge-Type Scaffold as a Small-Diameter Arterial Graft.

Sugiura T, Tara S, Nakayama H, Kurobe H, Yi T, Lee YU, Lee AY, Breuer CK, Shinoka T.

Ann Thorac Surg. 2016 Sep;102(3):720-727. doi: 10.1016/j.athoracsur.2016.01.110. Epub 2016 May 4.

34.

TGF-β receptor 1 inhibition prevents stenosis of tissue-engineered vascular grafts by reducing host mononuclear phagocyte activation.

Lee YU, de Dios Ruiz-Rosado J, Mahler N, Best CA, Tara S, Yi T, Shoji T, Sugiura T, Lee AY, Robledo-Avila F, Hibino N, Pober JS, Shinoka T, Partida-Sanchez S, Breuer CK.

FASEB J. 2016 Jul;30(7):2627-36. doi: 10.1096/fj.201500179R. Epub 2016 Apr 8.

35.

Long-Term Functional Efficacy of a Novel Electrospun Poly(Glycerol Sebacate)-Based Arterial Graft in Mice.

Khosravi R, Best CA, Allen RA, Stowell CE, Onwuka E, Zhuang JJ, Lee YU, Yi T, Bersi MR, Shinoka T, Humphrey JD, Wang Y, Breuer CK.

Ann Biomed Eng. 2016 Aug;44(8):2402-16. doi: 10.1007/s10439-015-1545-7. Epub 2016 Jan 21.

36.

3D-Printed Biodegradable Polymeric Vascular Grafts.

Melchiorri AJ, Hibino N, Best CA, Yi T, Lee YU, Kraynak CA, Kimerer LK, Krieger A, Kim P, Breuer CK, Fisher JP.

Adv Healthc Mater. 2016 Feb 4;5(3):319-325. doi: 10.1002/adhm.201500725. Epub 2015 Dec 2.

37.

Effect of cell seeding on neotissue formation in a tissue engineered trachea.

Clark ES, Best C, Onwuka E, Sugiura T, Mahler N, Bolon B, Niehaus A, James I, Hibino N, Shinoka T, Johnson J, Breuer CK.

J Pediatr Surg. 2016 Jan;51(1):49-55. doi: 10.1016/j.jpedsurg.2015.10.008. Epub 2015 Oct 22.

38.

A mouse model of endocardial fibroelastosis.

Clark ES, Pepper VK, Best CA, Onwuka EA, Yi T, Tara S, Cianciolo R, Baker P, Shinoka T, Breuer CK.

Cardiovasc Pathol. 2015 Nov-Dec;24(6):388-94. doi: 10.1016/j.carpath.2015.08.002. Epub 2015 Aug 8.

39.

Influence of Posttransplant Lymphoproliferative Disorder on Survival in Children After Heart Transplantation.

Hayes D Jr, Breuer CK, Horwitz EM, Yates AR, Tobias JD, Shinoka T.

Pediatr Cardiol. 2015 Dec;36(8):1748-53. doi: 10.1007/s00246-015-1229-y. Epub 2015 Jul 18.

PMID:
26187515
40.

Cilostazol, Not Aspirin, Prevents Stenosis of Bioresorbable Vascular Grafts in a Venous Model.

Tara S, Kurobe H, de Dios Ruiz Rosado J, Best CA, Shoji T, Mahler N, Yi T, Lee YU, Sugiura T, Hibino N, Partida-Sanchez S, Breuer CK, Shinoka T.

Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):2003-10. doi: 10.1161/ATVBAHA.115.306027. Epub 2015 Jul 16.

41.

C-Cell Neoplasia in Asymptomatic Carriers of RET Mutation in Extracellular Cysteine-Rich and Intracellular Tyrosine Kinase Domain.

Abi-Raad R, Virk RK, Dinauer CA, Prasad A, Morotti RA, Breuer CK, Sosa JA, Udelsman R, Rivkees SA, Prasad ML.

Hum Pathol. 2015 Aug;46(8):1121-8. doi: 10.1016/j.humpath.2015.04.011. Epub 2015 May 6.

PMID:
26033033
42.

Hemodynamic Characterization of a Mouse Model for Investigating the Cellular and Molecular Mechanisms of Neotissue Formation in Tissue-Engineered Heart Valves.

James IA, Yi T, Tara S, Best CA, Stuber AJ, Shah KV, Austin BF, Sugiura T, Lee YU, Lincoln J, Trask AJ, Shinoka T, Breuer CK.

Tissue Eng Part C Methods. 2015 Sep;21(9):987-94. doi: 10.1089/ten.TEC.2015.0011. Epub 2015 May 29.

43.

Development of small diameter nanofiber tissue engineered arterial grafts.

Kurobe H, Maxfield MW, Tara S, Rocco KA, Bagi PS, Yi T, Udelsman B, Zhuang ZW, Cleary M, Iwakiri Y, Breuer CK, Shinoka T.

PLoS One. 2015 Apr 1;10(4):e0120328. doi: 10.1371/journal.pone.0120328. eCollection 2015.

44.

Biomechanical diversity despite mechanobiological stability in tissue engineered vascular grafts two years post-implantation.

Khosravi R, Miller KS, Best CA, Shih YC, Lee YU, Yi T, Shinoka T, Breuer CK, Humphrey JD.

Tissue Eng Part A. 2015 May;21(9-10):1529-38. doi: 10.1089/ten.tea.2014.0524. Epub 2015 Feb 24.

45.

TGFβR1 inhibition blocks the formation of stenosis in tissue-engineered vascular grafts.

Duncan DR, Chen PY, Patterson JT, Lee YU, Hibino N, Cleary M, Naito Y, Yi T, Gilliland T, Kurobe H, Church SN, Shinoka T, Fahmy TM, Simons M, Breuer CK.

J Am Coll Cardiol. 2015 Feb 10;65(5):512-4. doi: 10.1016/j.jacc.2014.08.057. No abstract available.

46.

Well-organized neointima of large-pore poly(L-lactic acid) vascular graft coated with poly(L-lactic-co-ε-caprolactone) prevents calcific deposition compared to small-pore electrospun poly(L-lactic acid) graft in a mouse aortic implantation model.

Tara S, Kurobe H, Rocco KA, Maxfield MW, Best CA, Yi T, Naito Y, Breuer CK, Shinoka T.

Atherosclerosis. 2014 Dec;237(2):684-91. doi: 10.1016/j.atherosclerosis.2014.09.030. Epub 2014 Oct 17.

47.

Comparison of the biological equivalence of two methods for isolating bone marrow mononuclear cells for fabricating tissue-engineered vascular grafts.

Kurobe H, Tara S, Maxfield MW, Rocco KA, Bagi PS, Yi T, Udelsman BV, Dean EW, Khosravi R, Powell HM, Shinoka T, Breuer CK.

Tissue Eng Part C Methods. 2015 Jun;21(6):597-604. doi: 10.1089/ten.TEC.2014.0442. Epub 2014 Dec 29.

48.

A hypothesis-driven parametric study of effects of polymeric scaffold properties on tissue engineered neovessel formation.

Miller KS, Khosravi R, Breuer CK, Humphrey JD.

Acta Biomater. 2015 Jan;11:283-94. doi: 10.1016/j.actbio.2014.09.046. Epub 2014 Oct 5.

49.

Transplantation of pulmonary valve using a mouse model of heterotopic heart transplantation.

Lee YU, Yi T, James I, Tara S, Stuber AJ, Shah KV, Lee AY, Sugiura T, Hibino N, Shinoka T, Breuer CK.

J Vis Exp. 2014 Jul 23;(89). doi: 10.3791/51695.

50.

Implantation of inferior vena cava interposition graft in mouse model.

Lee YU, Yi T, Tara S, Lee AY, Hibino N, Shinoka T, Breuer CK.

J Vis Exp. 2014 Jun 4;(88). doi: 10.3791/51632.

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