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Items: 1 to 50 of 163

1.

Two Nimrod receptors, NimC1 and Eater, synergistically contribute to bacterial phagocytosis in Drosophila melanogaster.

Melcarne C, Ramond E, Dudzic J, Bretscher AJ, Kurucz É, Andó I, Lemaitre B.

FEBS J. 2019 Apr 16. doi: 10.1111/febs.14857. [Epub ahead of print]

PMID:
30993828
2.

Regulation of actin-based apical structures on epithelial cells.

Pelaseyed T, Bretscher A.

J Cell Sci. 2018 Oct 17;131(20). pii: jcs221853. doi: 10.1242/jcs.221853. Review.

3.

Yeast Aim21/Tda2 both regulates free actin by reducing barbed end assembly and forms a complex with Cap1/Cap2 to balance actin assembly between patches and cables.

Shin M, van Leeuwen J, Boone C, Bretscher A.

Mol Biol Cell. 2018 Apr 15;29(8):923-936. doi: 10.1091/mbc.E17-10-0592. Epub 2018 Mar 30.

4.

Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism.

Pelaseyed T, Viswanatha R, Sauvanet C, Filter JJ, Goldberg ML, Bretscher A.

Elife. 2017 Apr 21;6. pii: e22759. doi: 10.7554/eLife.22759.

5.

Kinesin-related Smy1 enhances the Rab-dependent association of myosin-V with secretory cargo.

Lwin KM, Li D, Bretscher A.

Mol Biol Cell. 2016 Aug 1;27(15):2450-62. doi: 10.1091/mbc.E16-03-0185. Epub 2016 Jun 15.

6.

Structure, regulation, and functional diversity of microvilli on the apical domain of epithelial cells.

Sauvanet C, Wayt J, Pelaseyed T, Bretscher A.

Annu Rev Cell Dev Biol. 2015;31:593-621. doi: 10.1146/annurev-cellbio-100814-125234. Review.

PMID:
26566117
7.

The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation.

Sauvanet C, Garbett D, Bretscher A.

Mol Biol Cell. 2015 Oct 15;26(20):3615-27. doi: 10.1091/mbc.E15-07-0498. Epub 2015 Aug 26.

8.

Tracking individual secretory vesicles during exocytosis reveals an ordered and regulated process.

Donovan KW, Bretscher A.

J Cell Biol. 2015 Jul 20;210(2):181-9. doi: 10.1083/jcb.201501118. Epub 2015 Jul 13.

9.

Head-to-tail regulation is critical for the in vivo function of myosin V.

Donovan KW, Bretscher A.

J Cell Biol. 2015 May 11;209(3):359-65. doi: 10.1083/jcb.201411010. Epub 2015 May 4.

10.

The Nimrod transmembrane receptor Eater is required for hemocyte attachment to the sessile compartment in Drosophila melanogaster.

Bretscher AJ, Honti V, Binggeli O, Burri O, Poidevin M, Kurucz É, Zsámboki J, Andó I, Lemaitre B.

Biol Open. 2015 Feb 13;4(3):355-63. doi: 10.1242/bio.201410595.

11.

Rapid glucose depletion immobilizes active myosin V on stabilized actin cables.

Xu L, Bretscher A.

Curr Biol. 2014 Oct 20;24(20):2471-9. doi: 10.1016/j.cub.2014.09.017. Epub 2014 Oct 9.

12.

The surprising dynamics of scaffolding proteins.

Garbett D, Bretscher A.

Mol Biol Cell. 2014 Aug 15;25(16):2315-9. doi: 10.1091/mbc.E14-04-0878.

13.

Cordon Bleu serves as a platform at the basal region of microvilli, where it regulates microvillar length through its WH2 domains.

Wayt J, Bretscher A.

Mol Biol Cell. 2014 Sep 15;25(18):2817-27. doi: 10.1091/mbc.E14-06-1131. Epub 2014 Jul 16.

14.

Methods to study Drosophila immunity.

Neyen C, Bretscher AJ, Binggeli O, Lemaitre B.

Methods. 2014 Jun 15;68(1):116-28. doi: 10.1016/j.ymeth.2014.02.023. Epub 2014 Mar 12. Review.

PMID:
24631888
15.

Dynamics of ezrin and EBP50 in regulating microvilli on the apical aspect of epithelial cells.

Viswanatha R, Bretscher A, Garbett D.

Biochem Soc Trans. 2014 Feb;42(1):189-94. doi: 10.1042/BST20130263.

16.

CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.

Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, Gutmann DH, Hanemann CO, Hennigan R, Huson S, Ingram D, Kissil J, Korf BR, Legius E, Packer RJ, McClatchey AI, McCormick F, North K, Pehrsson M, Plotkin SR, Ramesh V, Ratner N, Schirmer S, Sherman L, Schorry E, Stevenson D, Stewart DR, Ullrich N, Bakker AC, Morrison H.

Am J Med Genet A. 2014 Mar;164A(3):563-78. doi: 10.1002/ajmg.a.36312. Epub 2014 Jan 17.

17.

Cross-modulation of homeostatic responses to temperature, oxygen and carbon dioxide in C. elegans.

Kodama-Namba E, Fenk LA, Bretscher AJ, Gross E, Busch KE, de Bono M.

PLoS Genet. 2013;9(12):e1004011. doi: 10.1371/journal.pgen.1004011. Epub 2013 Dec 19.

18.

Deconstructing formin-dependent actin cable assembly.

Bretscher A.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18744-5. doi: 10.1073/pnas.1318683110. Epub 2013 Oct 31. No abstract available.

19.

Interactome analysis reveals ezrin can adopt multiple conformational states.

Viswanatha R, Wayt J, Ohouo PY, Smolka MB, Bretscher A.

J Biol Chem. 2013 Dec 6;288(49):35437-51. doi: 10.1074/jbc.M113.505669. Epub 2013 Oct 22.

20.

Active segregation of yeast mitochondria by Myo2 is essential and mediated by Mmr1 and Ypt11.

Chernyakov I, Santiago-Tirado F, Bretscher A.

Curr Biol. 2013 Sep 23;23(18):1818-24. doi: 10.1016/j.cub.2013.07.053. Epub 2013 Sep 5.

21.

The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics.

Garbett D, Sauvanet C, Viswanatha R, Bretscher A.

Mol Biol Cell. 2013 Nov;24(21):3381-92. doi: 10.1091/mbc.E13-06-0330. Epub 2013 Aug 28.

22.

Magazine or journal--what is the difference? The role of the monitoring editor.

Bretscher A.

Mol Biol Cell. 2013 Apr;24(7):887-9. doi: 10.1091/mbc.E12-12-0899.

23.

Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells.

Viswanatha R, Ohouo PY, Smolka MB, Bretscher A.

J Cell Biol. 2012 Dec 10;199(6):969-84. doi: 10.1083/jcb.201207047. Epub 2012 Dec 3.

24.

Myosin-V is activated by binding secretory cargo and released in coordination with Rab/exocyst function.

Donovan KW, Bretscher A.

Dev Cell. 2012 Oct 16;23(4):769-81. doi: 10.1016/j.devcel.2012.09.001.

25.

PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilli.

Garbett D, Bretscher A.

J Cell Biol. 2012 Jul 23;198(2):195-203. doi: 10.1083/jcb.201204008. Epub 2012 Jul 16.

26.

Z-line formins promote contractile lattice growth and maintenance in striated muscles of C. elegans.

Mi-Mi L, Votra S, Kemphues K, Bretscher A, Pruyne D.

J Cell Biol. 2012 Jul 9;198(1):87-102. doi: 10.1083/jcb.201202053. Epub 2012 Jul 2.

27.

The tumor suppressor merlin controls growth in its open state, and phosphorylation converts it to a less-active more-closed state.

Sher I, Hanemann CO, Karplus PA, Bretscher A.

Dev Cell. 2012 Apr 17;22(4):703-5. doi: 10.1016/j.devcel.2012.03.008. No abstract available.

28.

EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking.

Hokanson DE, Bretscher AP.

Mol Biol Cell. 2012 Feb;23(4):701-15. doi: 10.1091/mbc.E11-06-0521. Epub 2012 Jan 4.

29.

Yeast formin Bni1p has multiple localization regions that function in polarized growth and spindle orientation.

Liu W, Santiago-Tirado FH, Bretscher A.

Mol Biol Cell. 2012 Feb;23(3):412-22. doi: 10.1091/mbc.E11-07-0631. Epub 2011 Dec 7.

30.

Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network.

Santiago-Tirado FH, Bretscher A.

Trends Cell Biol. 2011 Sep;21(9):515-25. doi: 10.1016/j.tcb.2011.05.005. Epub 2011 Jul 19. Review.

31.

Temperature, oxygen, and salt-sensing neurons in C. elegans are carbon dioxide sensors that control avoidance behavior.

Bretscher AJ, Kodama-Namba E, Busch KE, Murphy RJ, Soltesz Z, Laurent P, de Bono M.

Neuron. 2011 Mar 24;69(6):1099-113. doi: 10.1016/j.neuron.2011.02.023.

32.

PI4P and Rab inputs collaborate in myosin-V-dependent transport of secretory compartments in yeast.

Santiago-Tirado FH, Legesse-Miller A, Schott D, Bretscher A.

Dev Cell. 2011 Jan 18;20(1):47-59. doi: 10.1016/j.devcel.2010.11.006.

33.

The UBX protein SAKS1 negatively regulates endoplasmic reticulum-associated degradation and p97-dependent degradation.

LaLonde DP, Bretscher A.

J Biol Chem. 2011 Feb 11;286(6):4892-901. doi: 10.1074/jbc.M110.158030. Epub 2010 Dec 6.

34.

The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent manner.

Garbett D, LaLonde DP, Bretscher A.

J Cell Biol. 2010 Oct 18;191(2):397-413. doi: 10.1083/jcb.201004115. Epub 2010 Oct 11.

35.

Organizing the cell cortex: the role of ERM proteins.

Fehon RG, McClatchey AI, Bretscher A.

Nat Rev Mol Cell Biol. 2010 Apr;11(4):276-87. doi: 10.1038/nrm2866. Review. Erratum in: Nat Rev Mol Cell Biol. 2010 Sep;11(9):674.

36.

A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization.

LaLonde DP, Garbett D, Bretscher A.

Mol Biol Cell. 2010 May 1;21(9):1519-29. doi: 10.1091/mbc.E10-01-0008. Epub 2010 Mar 17.

37.

The yeast formin Bnr1p has two localization regions that show spatially and temporally distinct association with septin structures.

Gao L, Liu W, Bretscher A.

Mol Biol Cell. 2010 Apr 1;21(7):1253-62. doi: 10.1091/mbc.E09-10-0861. Epub 2010 Feb 10.

38.

Epithelial polarity: dual Lkb1 pathways regulate apical microvilli.

Bretscher A.

Dev Cell. 2009 Apr;16(4):491-2. doi: 10.1016/j.devcel.2009.03.012.

39.

T cell antigen receptor signaling and immunological synapse stability require myosin IIA.

Ilani T, Vasiliver-Shamis G, Vardhana S, Bretscher A, Dustin ML.

Nat Immunol. 2009 May;10(5):531-9. doi: 10.1038/ni.1723. Epub 2009 Apr 6.

40.

Polarized growth in budding yeast in the absence of a localized formin.

Gao L, Bretscher A.

Mol Biol Cell. 2009 May;20(10):2540-8. doi: 10.1091/mbc.E09-03-0194. Epub 2009 Mar 18.

41.
42.

A carbon dioxide avoidance behavior is integrated with responses to ambient oxygen and food in Caenorhabditis elegans.

Bretscher AJ, Busch KE, de Bono M.

Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):8044-9. doi: 10.1073/pnas.0707607105. Epub 2008 Jun 4.

43.

Analysis of unregulated formin activity reveals how yeast can balance F-actin assembly between different microfilament-based organizations.

Gao L, Bretscher A.

Mol Biol Cell. 2008 Apr;19(4):1474-84. doi: 10.1091/mbc.E07-05-0520. Epub 2008 Jan 30.

44.

Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.

Ilani T, Khanna C, Zhou M, Veenstra TD, Bretscher A.

J Cell Biol. 2007 Nov 19;179(4):733-46.

45.

Expression of the cytoskeleton linker protein ezrin in human cancers.

Bruce B, Khanna G, Ren L, Landberg G, Jirström K, Powell C, Borczuk A, Keller ET, Wojno KJ, Meltzer P, Baird K, McClatchey A, Bretscher A, Hewitt SM, Khanna C.

Clin Exp Metastasis. 2007;24(2):69-78. Epub 2007 Mar 17.

PMID:
17370041
46.

EPI64 regulates microvillar subdomains and structure.

Hanono A, Garbett D, Reczek D, Chambers DN, Bretscher A.

J Cell Biol. 2006 Dec 4;175(5):803-13.

47.
48.

Self-masking in an intact ERM-merlin protein: an active role for the central alpha-helical domain.

Li Q, Nance MR, Kulikauskas R, Nyberg K, Fehon R, Karplus PA, Bretscher A, Tesmer JJ.

J Mol Biol. 2007 Feb 2;365(5):1446-59. Epub 2006 Oct 26.

49.

Regulated phosphorylation of budding yeast's essential myosin V heavy chain, Myo2p.

Legesse-Miller A, Zhang S, Santiago-Tirado FH, Van Pelt CK, Bretscher A.

Mol Biol Cell. 2006 Apr;17(4):1812-21. Epub 2006 Feb 8.

50.

Microtubule tips redirect actin assembly.

Bretscher A.

Dev Cell. 2005 Apr;8(4):458-9.

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