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Items: 1 to 50 of 53

1.

The hepatitis C virus RNA-dependent RNA polymerase directs incoming nucleotides to its active site through magnesium-dependent dynamics within its F motif.

Ben Ouirane K, Boulard Y, Bressanelli S.

J Biol Chem. 2019 May 10;294(19):7573-7587. doi: 10.1074/jbc.RA118.005209. Epub 2019 Mar 13.

PMID:
30867194
2.

Septin 9 has Two Polybasic Domains Critical to Septin Filament Assembly and Golgi Integrity.

Omrane M, Camara AS, Taveneau C, Benzoubir N, Tubiana T, Yu J, Guérois R, Samuel D, Goud B, Poüs C, Bressanelli S, Garratt RC, Thiam AR, Gassama-Diagne A.

iScience. 2019 Mar 29;13:138-153. doi: 10.1016/j.isci.2019.02.015. Epub 2019 Feb 19.

3.

TTClust: A Versatile Molecular Simulation Trajectory Clustering Program with Graphical Summaries.

Tubiana T, Carvaillo JC, Boulard Y, Bressanelli S.

J Chem Inf Model. 2018 Nov 26;58(11):2178-2182. doi: 10.1021/acs.jcim.8b00512. Epub 2018 Oct 30.

PMID:
30351057
4.

Nonequilibrium self-assembly dynamics of icosahedral viral capsids packaging genome or polyelectrolyte.

Chevreuil M, Law-Hine D, Chen J, Bressanelli S, Combet S, Constantin D, Degrouard J, Möller J, Zeghal M, Tresset G.

Nat Commun. 2018 Aug 6;9(1):3071. doi: 10.1038/s41467-018-05426-8.

5.

Localizing Conformational Hinges by NMR: Where Do Hepatitis B Virus Core Proteins Adapt for Capsid Assembly?

Lecoq L, Wang S, Wiegand T, Bressanelli S, Nassal M, Meier BH, Böckmann A.

Chemphyschem. 2018 Jun 5;19(11):1336-1340. doi: 10.1002/cphc.201800211. Epub 2018 Apr 6.

PMID:
29542854
6.

Solid-state [13C-15N] NMR resonance assignment of hepatitis B virus core protein.

Lecoq L, Wang S, Wiegand T, Bressanelli S, Nassal M, Meier BH, Böckmann A.

Biomol NMR Assign. 2018 Apr;12(1):205-214. doi: 10.1007/s12104-018-9810-y. Epub 2018 Feb 16.

PMID:
29450824
7.

Identification and Molecular Characterization of the Chloroplast Targeting Domain of Turnip yellow mosaic virus Replication Proteins.

Moriceau L, Jomat L, Bressanelli S, Alcaide-Loridan C, Jupin I.

Front Plant Sci. 2017 Dec 19;8:2138. doi: 10.3389/fpls.2017.02138. eCollection 2017.

8.

A mobile loop near the active site acts as a switch between the dual activities of a viral protease/deubiquitinase.

Jupin I, Ayach M, Jomat L, Fieulaine S, Bressanelli S.

PLoS Pathog. 2017 Nov 8;13(11):e1006714. doi: 10.1371/journal.ppat.1006714. eCollection 2017 Nov.

9.

Membrane alterations induced by nonstructural proteins of human norovirus.

Doerflinger SY, Cortese M, Romero-Brey I, Menne Z, Tubiana T, Schenk C, White PA, Bartenschlager R, Bressanelli S, Hansman GS, Lohmann V.

PLoS Pathog. 2017 Oct 27;13(10):e1006705. doi: 10.1371/journal.ppat.1006705. eCollection 2017 Oct.

10.

Dynamics and asymmetry in the dimer of the norovirus major capsid protein.

Tubiana T, Boulard Y, Bressanelli S.

PLoS One. 2017 Jul 27;12(7):e0182056. doi: 10.1371/journal.pone.0182056. eCollection 2017.

11.

Structural intermediates in the fusion-associated transition of vesiculovirus glycoprotein.

Baquero E, Albertini AA, Raux H, Abou-Hamdan A, Boeri-Erba E, Ouldali M, Buonocore L, Rose JK, Lepault J, Bressanelli S, Gaudin Y.

EMBO J. 2017 Mar 1;36(5):679-692. doi: 10.15252/embj.201694565. Epub 2017 Feb 10.

12.

Identification of a major intermediate along the self-assembly pathway of an icosahedral viral capsid by using an analytical model of a spherical patch.

Law-Hine D, Zeghal M, Bressanelli S, Constantin D, Tresset G.

Soft Matter. 2016 Aug 10;12(32):6728-36. doi: 10.1039/c6sm01060a.

PMID:
27444997
13.

Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV.

Akil A, Peng J, Omrane M, Gondeau C, Desterke C, Marin M, Tronchère H, Taveneau C, Sar S, Briolotti P, Benjelloun S, Benjouad A, Maurel P, Thiers V, Bressanelli S, Samuel D, Bréchot C, Gassama-Diagne A.

Nat Commun. 2016 Jul 15;7:12203. doi: 10.1038/ncomms12203.

14.

Reconstruction of the Disassembly Pathway of an Icosahedral Viral Capsid and Shape Determination of Two Successive Intermediates.

Law-Hine D, Sahoo AK, Bailleux V, Zeghal M, Prevost S, Maiti PK, Bressanelli S, Constantin D, Tresset G.

J Phys Chem Lett. 2015 Sep 3;6(17):3471-6. doi: 10.1021/acs.jpclett.5b01478. Epub 2015 Aug 24.

PMID:
27120684
15.

Derivation of original RESP atomic partial charges for MD simulations of the LDAO surfactant with AMBER: applications to a model of micelle and a fragment of the lipid kinase PI4KA.

Karakas E, Taveneau C, Bressanelli S, Marchi M, Robert B, Abel S.

J Biomol Struct Dyn. 2017 Jan;35(1):159-181. doi: 10.1080/07391102.2015.1135822. Epub 2016 Mar 21.

PMID:
26998712
16.

Atomic view of the histidine environment stabilizing higher-pH conformations of pH-dependent proteins.

Valéry C, Deville-Foillard S, Lefebvre C, Taberner N, Legrand P, Meneau F, Meriadec C, Delvaux C, Bizien T, Kasotakis E, Lopez-Iglesias C, Gall A, Bressanelli S, Le Du MH, Paternostre M, Artzner F.

Nat Commun. 2015 Jul 20;6:7771. doi: 10.1038/ncomms8771.

17.

Definition and expression in E. coli of large fragments from the human lipid kinase phosphatidylinositol 4-kinase type III alpha, and purification of a 1100-residue N-terminal module.

Taveneau C, Blondeau K, Bressanelli S.

Protein Expr Purif. 2015 Oct;114:121-7. doi: 10.1016/j.pep.2015.06.018. Epub 2015 Jul 2.

PMID:
26145834
18.

Crystallization of mutants of Turnip yellow mosaic virus protease/ubiquitin hydrolase designed to prevent protease self-recognition.

Ayach M, Bressanelli S.

Acta Crystallogr F Struct Biol Commun. 2015 Apr;71(Pt 4):405-8. doi: 10.1107/S2053230X15003945. Epub 2015 Mar 20.

19.

Structure of the low pH conformation of Chandipura virus G reveals important features in the evolution of the vesiculovirus glycoprotein.

Baquero E, Albertini AA, Raux H, Buonocore L, Rose JK, Bressanelli S, Gaudin Y.

PLoS Pathog. 2015 Mar 24;11(3):e1004756. doi: 10.1371/journal.ppat.1004756. eCollection 2015 Mar.

20.

Insights into herpesvirus tegument organization from structural analyses of the 970 central residues of HSV-1 UL36 protein.

Scrima N, Lepault J, Boulard Y, Pasdeloup D, Bressanelli S, Roche S.

J Biol Chem. 2015 Apr 3;290(14):8820-33. doi: 10.1074/jbc.M114.612838. Epub 2015 Feb 12.

21.

Structural biology. Kickstarting a viral RNA polymerase.

Bressanelli S.

Science. 2015 Feb 13;347(6223):715-6. doi: 10.1126/science.aaa5980. No abstract available.

PMID:
25678645
22.

Prevalence and phylogenetic analysis of tick-borne encephalitis virus (TBEV) in field-collected ticks (Ixodes ricinus) in southern Switzerland.

Rieille N, Bressanelli S, Freire CC, Arcioni S, Gern L, Péter O, Voordouw MJ.

Parasit Vectors. 2014 Sep 22;7:443. doi: 10.1186/1756-3305-7-443.

23.

Conserved aromatic residues of the hepatitis B virus Precore propeptide are involved in a switch between distinct dimeric conformations and essential in the formation of heterocapsids.

Duriez M, Thouard A, Bressanelli S, Rossignol JM, Sitterlin D.

Virology. 2014 Aug;462-463:273-82. doi: 10.1016/j.virol.2014.06.013. Epub 2014 Jul 5.

24.

Mapping of functional domains of the lipid kinase phosphatidylinositol 4-kinase type III alpha involved in enzymatic activity and hepatitis C virus replication.

Harak C, Radujkovic D, Taveneau C, Reiss S, Klein R, Bressanelli S, Lohmann V.

J Virol. 2014 Sep 1;88(17):9909-26. doi: 10.1128/JVI.01063-14. Epub 2014 Jun 11.

25.

Polymerases of hepatitis C viruses and flaviviruses: structural and mechanistic insights and drug development.

Caillet-Saguy C, Lim SP, Shi PY, Lescar J, Bressanelli S.

Antiviral Res. 2014 May;105:8-16. doi: 10.1016/j.antiviral.2014.02.006. Epub 2014 Feb 19. Review.

PMID:
24561230
26.

A compact viral processing proteinase/ubiquitin hydrolase from the OTU family.

Lombardi C, Ayach M, Beaurepaire L, Chenon M, Andreani J, Guerois R, Jupin I, Bressanelli S.

PLoS Pathog. 2013 Aug;9(8):e1003560. doi: 10.1371/journal.ppat.1003560. Epub 2013 Aug 15.

27.

Unusual self-assembly properties of Norovirus Newbury2 virus-like particles.

Tresset G, Decouche V, Bryche JF, Charpilienne A, Le Cœur C, Barbier C, Squires G, Zeghal M, Poncet D, Bressanelli S.

Arch Biochem Biophys. 2013 Sep 1;537(1):144-52. doi: 10.1016/j.abb.2013.07.003. Epub 2013 Jul 18.

PMID:
23871846
28.

Norovirus capsid proteins self-assemble through biphasic kinetics via long-lived stave-like intermediates.

Tresset G, Le Coeur C, Bryche JF, Tatou M, Zeghal M, Charpilienne A, Poncet D, Constantin D, Bressanelli S.

J Am Chem Soc. 2013 Oct 16;135(41):15373-81. doi: 10.1021/ja403550f. Epub 2013 Jul 3.

PMID:
23822934
29.

Structure of the Triatoma virus capsid.

Squires G, Pous J, Agirre J, Rozas-Dennis GS, Costabel MD, Marti GA, Navaza J, Bressanelli S, Guérin DM, Rey FA.

Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):1026-37. doi: 10.1107/S0907444913004617. Epub 2013 May 14.

30.

Intermediate conformations during viral fusion glycoprotein structural transition.

Baquero E, Albertini AA, Vachette P, Lepault J, Bressanelli S, Gaudin Y.

Curr Opin Virol. 2013 Apr;3(2):143-50. doi: 10.1016/j.coviro.2013.03.006. Epub 2013 Apr 3. Review.

PMID:
23562213
31.

Crystallization and preliminary X-ray analysis of Chandipura virus glycoprotein G.

Baquero E, Buonocore L, Rose JK, Bressanelli S, Gaudin Y, Albertini AA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Sep 1;68(Pt 9):1094-7. doi: 10.1107/S1744309112030151. Epub 2012 Aug 31.

32.

Two crucial early steps in RNA synthesis by the hepatitis C virus polymerase involve a dual role of residue 405.

Scrima N, Caillet-Saguy C, Ventura M, Harrus D, Astier-Gin T, Bressanelli S.

J Virol. 2012 Jul;86(13):7107-17. doi: 10.1128/JVI.00459-12. Epub 2012 Apr 24.

33.

In praise of impurity: 30S ribosomal S15 protein-assisted crystallization of turnip yellow mosaic virus proteinase.

Robin C, Beaurepaire L, Chenon M, Jupin I, Bressanelli S.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Apr 1;68(Pt 4):486-90. doi: 10.1107/S1744309112008445. Epub 2012 Mar 28.

34.

Characterization of monomeric intermediates during VSV glycoprotein structural transition.

Albertini AA, Mérigoux C, Libersou S, Madiona K, Bressanelli S, Roche S, Lepault J, Melki R, Vachette P, Gaudin Y.

PLoS Pathog. 2012 Feb;8(2):e1002556. doi: 10.1371/journal.ppat.1002556. Epub 2012 Feb 23.

35.

An objective assessment of conformational variability in complexes of hepatitis C virus polymerase with non-nucleoside inhibitors.

Caillet-Saguy C, Simister PC, Bressanelli S.

J Mol Biol. 2011 Dec 2;414(3):370-84. doi: 10.1016/j.jmb.2011.10.001. Epub 2011 Oct 8.

PMID:
22008450
36.

Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations.

Neumann-Haefelin C, Oniangue-Ndza C, Kuntzen T, Schmidt J, Nitschke K, Sidney J, Caillet-Saguy C, Binder M, Kersting N, Kemper MW, Power KA, Ingber S, Reyor LL, Hills-Evans K, Kim AY, Lauer GM, Lohmann V, Sette A, Henn MR, Bressanelli S, Thimme R, Allen TM.

Hepatology. 2011 Oct;54(4):1157-66. doi: 10.1002/hep.24541.

37.

Structure and working of viral fusion machinery.

Albertini A, Bressanelli S, Lepault J, Gaudin Y.

Curr Top Membr. 2011;68:49-80. doi: 10.1016/B978-0-12-385891-7.00003-9. Review. No abstract available.

PMID:
21771495
38.

A comprehensive structure-function comparison of hepatitis C virus strain JFH1 and J6 polymerases reveals a key residue stimulating replication in cell culture across genotypes.

Schmitt M, Scrima N, Radujkovic D, Caillet-Saguy C, Simister PC, Friebe P, Wicht O, Klein R, Bartenschlager R, Lohmann V, Bressanelli S.

J Virol. 2011 Mar;85(6):2565-81. doi: 10.1128/JVI.02177-10. Epub 2011 Jan 5.

39.

Further insights into the roles of GTP and the C terminus of the hepatitis C virus polymerase in the initiation of RNA synthesis.

Harrus D, Ahmed-El-Sayed N, Simister PC, Miller S, Triconnet M, Hagedorn CH, Mahias K, Rey FA, Astier-Gin T, Bressanelli S.

J Biol Chem. 2010 Oct 22;285(43):32906-18. doi: 10.1074/jbc.M110.151316. Epub 2010 Aug 20.

40.

Structural and functional analysis of hepatitis C virus strain JFH1 polymerase.

Simister P, Schmitt M, Geitmann M, Wicht O, Danielson UH, Klein R, Bressanelli S, Lohmann V.

J Virol. 2009 Nov;83(22):11926-39. doi: 10.1128/JVI.01008-09. Epub 2009 Sep 9.

41.

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.

Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, McKiernan S, Kelleher D, Gruener N, Tavis JE, Rosen HR, Shaw J, Bowness P, Blum HE, Klenerman P, Bartenschlager R, Thimme R.

J Clin Invest. 2009 Feb;119(2):376-86. doi: 10.1172/JCI36587. Epub 2009 Jan 12.

42.

Structures of vesicular stomatitis virus glycoprotein: membrane fusion revisited.

Roche S, Albertini AA, Lepault J, Bressanelli S, Gaudin Y.

Cell Mol Life Sci. 2008 Jun;65(11):1716-28. doi: 10.1007/s00018-008-7534-3. Review.

PMID:
18345480
43.

Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.

Assenberg R, Ren J, Verma A, Walter TS, Alderton D, Hurrelbrink RJ, Fuller SD, Bressanelli S, Owens RJ, Stuart DI, Grimes JM.

J Gen Virol. 2007 Aug;88(Pt 8):2228-36.

PMID:
17622627
44.

Crystal structure of a human autoimmune complex between IgM rheumatoid factor RF61 and IgG1 Fc reveals a novel epitope and evidence for affinity maturation.

Duquerroy S, Stura EA, Bressanelli S, Fabiane SM, Vaney MC, Beale D, Hamon M, Casali P, Rey FA, Sutton BJ, Taussig MJ.

J Mol Biol. 2007 May 18;368(5):1321-31. Epub 2007 Mar 6.

45.

Structure of the prefusion form of the vesicular stomatitis virus glycoprotein G.

Roche S, Rey FA, Gaudin Y, Bressanelli S.

Science. 2007 Feb 9;315(5813):843-8.

46.

Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G.

Roche S, Bressanelli S, Rey FA, Gaudin Y.

Science. 2006 Jul 14;313(5784):187-91. Erratum in: Science. 2006 Sep 8;313(5792):1389.

47.

The birnavirus crystal structure reveals structural relationships among icosahedral viruses.

Coulibaly F, Chevalier C, Gutsche I, Pous J, Navaza J, Bressanelli S, Delmas B, Rey FA.

Cell. 2005 Mar 25;120(6):761-72.

49.

Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation.

Bressanelli S, Stiasny K, Allison SL, Stura EA, Duquerroy S, Lescar J, Heinz FX, Rey FA.

EMBO J. 2004 Feb 25;23(4):728-38. Epub 2004 Feb 12.

50.

Scaffolds for protein crystallisation.

Stura EA, Taussig MJ, Sutton BJ, Duquerroy S, Bressanelli S, Minson AC, Rey FA.

Acta Crystallogr D Biol Crystallogr. 2002 Oct;58(Pt 10 Pt 1):1715-21. Epub 2002 Sep 26.

PMID:
12351893

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