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Items: 45

1.

Differences in circulating microRNA signature in Prader-Willi syndrome and non-syndromic obesity.

Pascut D, Tamini S, Bresolin S, Giraudi P, Basso G, Minocci A, Tiribelli C, Grugni G, Sartorio A.

Endocr Connect. 2018 Dec 1;7(12):1262-1274. doi: 10.1530/EC-18-0329.

2.

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells.

Portale F, Cricrì G, Bresolin S, Lupi M, Gaspari S, Silvestri D, Russo B, Marino N, Ubezio P, Pagni F, Vergani P, Te Kronnie G, Valsecchi MG, Locatelli F, Rizzari C, Biondi A, Dander E, D'Amico G.

Haematologica. 2018 Sep 27. pii: haematol.2018.188664. doi: 10.3324/haematol.2018.188664. [Epub ahead of print]

3.

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.

Jin Q, Martinez CA, Arcipowski KM, Zhu Y, Gutierrez-Diaz BT, Wang KK, Johnson MR, Volk AG, Wang F, Wu J, Grove C, Wang H, Sokirniy I, Thomas PM, Goo YA, Abshiru NA, Hijiya N, Peirs S, Vandamme N, Berx G, Goosens S, Marshall SA, Rendleman EJ, Takahashi YH, Wang L, Rawat R, Bartom ET, Collings CK, Van Vlierberghe P, Strikoudis A, Kelly S, Ueberheide B, Mantis C, Kandela I, Bourquin JP, Bornhauser B, Serafin V, Bresolin S, Paganin M, Accordi B, Basso G, Kelleher NL, Weinstock J, Kumar S, Crispino JD, Shilatifard A, Ntziachristos P.

Clin Cancer Res. 2019 Jan 1;25(1):222-239. doi: 10.1158/1078-0432.CCR-18-1740. Epub 2018 Sep 17.

PMID:
30224337
4.

Simultaneous B and T cell acute lymphoblastic leukemias in zebrafish driven by transgenic MYC: implications for oncogenesis and lymphopoiesis.

Borga C, Park G, Foster C, Burroughs-Garcia J, Marchesin M, Shah R, Hasan A, Ahmed ST, Bresolin S, Batchelor L, Scordino T, Miles RR, Te Kronnie G, Regens JL, Frazer JK.

Leukemia. 2018 Aug 15. doi: 10.1038/s41375-018-0226-6. [Epub ahead of print]

PMID:
30111845
5.

The long non-coding RNA landscape in juvenile myelomonocytic leukemia.

Hofmans M, Lammens T, Helsmoortel HH, Bresolin S, Cavé H, Flotho C, Hasle H, van den Heuvel-Eibrink MM, Niemeyer C, Stary J, Van Roy N, Van Vlierberghe P, Philippé J, De Moerloose B.

Haematologica. 2018 Nov;103(11):e501-e504. doi: 10.3324/haematol.2018.189977. Epub 2018 Jun 1. No abstract available.

6.

SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia.

Sarno J, Savino AM, Buracchi C, Palmi C, Pinto S, Bugarin C, Jager A, Bresolin S, Barber RC, Silvestri D, Israeli S, Dyer MJS, Cazzaniga G, Nolan GP, Biondi A, Davis KL, Gaipa G.

Oncotarget. 2018 May 1;9(33):22872-22885. doi: 10.18632/oncotarget.25089. eCollection 2018 May 1.

7.

AKR1C enzymes sustain therapy resistance in paediatric T-ALL.

Bortolozzi R, Bresolin S, Rampazzo E, Paganin M, Maule F, Mariotto E, Boso D, Minuzzo S, Agnusdei V, Viola G, Te Kronnie G, Cazzaniga G, Basso G, Persano L.

Br J Cancer. 2018 Apr;118(7):985-994. doi: 10.1038/s41416-018-0014-0. Epub 2018 Mar 8.

PMID:
29515258
8.

Somatic mutations activating Wiskott-Aldrich syndrome protein concomitant with RAS pathway mutations in juvenile myelomonocytic leukemia patients.

Coppe A, Nogara L, Pizzuto MS, Cani A, Cesaro S, Masetti R, Locatelli F, Te Kronnie G, Basso G, Bortoluzzi S, Bresolin S.

Hum Mutat. 2018 Apr;39(4):579-587. doi: 10.1002/humu.23399. Epub 2018 Jan 19.

PMID:
29316027
9.

Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia.

Serafin V, Capuzzo G, Milani G, Minuzzo SA, Pinazza M, Bortolozzi R, Bresolin S, Porcù E, Frasson C, Indraccolo S, Basso G, Accordi B.

Blood. 2017 Dec 21;130(25):2750-2761. doi: 10.1182/blood-2017-05-784603. Epub 2017 Nov 3.

10.

ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.

Germano G, Morello G, Aveic S, Pinazza M, Minuzzo S, Frasson C, Persano L, Bonvini P, Viola G, Bresolin S, Tregnago C, Paganin M, Pigazzi M, Indraccolo S, Basso G.

Oncotarget. 2017 Apr 18;8(16):26129-26141. doi: 10.18632/oncotarget.15387.

11.

ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype.

Zaliova M, Kotrova M, Bresolin S, Stuchly J, Stary J, Hrusak O, Te Kronnie G, Trka J, Zuna J, Vaskova M.

Genes Chromosomes Cancer. 2017 Aug;56(8):608-616. doi: 10.1002/gcc.22464. Epub 2017 May 5.

PMID:
28395118
12.

Expression Profiling of Circulating Microvesicles Reveals Intercellular Transmission of Oncogenic Pathways.

Milani G, Lana T, Bresolin S, Aveic S, Pastò A, Frasson C, Te Kronnie G.

Mol Cancer Res. 2017 Jun;15(6):683-695. doi: 10.1158/1541-7786.MCR-16-0307. Epub 2017 Feb 15.

13.

Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL.

Serafin V, Lissandron V, Buldini B, Bresolin S, Paganin M, Grillo F, Andriano N, Palmi C, Cazzaniga G, Marmiroli S, Conter V, Basso G, Accordi B.

Leukemia. 2017 Apr;31(4):1007-1011. doi: 10.1038/leu.2017.13. Epub 2017 Jan 13. No abstract available.

PMID:
28082737
14.

Profiling B cell chronic lymphocytic leukemia by reverse phase protein array: Focus on apoptotic proteins.

Frezzato F, Accordi B, Trimarco V, Gattazzo C, Martini V, Milani G, Bresolin S, Severin F, Visentin A, Basso G, Semenzato G, Trentin L.

J Leukoc Biol. 2016 Nov;100(5):1061-1070. Epub 2016 Jun 16.

PMID:
27312846
15.

NPM-ALK expression levels identify two distinct subtypes of paediatric anaplastic large cell lymphoma.

Pomari E, Basso G, Bresolin S, Pillon M, Carraro E, d'Amore ES, Viola G, Frasson C, Basso K, Bonvini P, Mussolin L.

Leukemia. 2017 Feb;31(2):498-501. doi: 10.1038/leu.2016.292. Epub 2016 Oct 24. No abstract available.

PMID:
27773932
16.

Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis.

Trentin L, Bresolin S, Giarin E, Bardini M, Serafin V, Accordi B, Fais F, Tenca C, De Lorenzo P, Valsecchi MG, Cazzaniga G, Kronnie GT, Basso G.

Sci Rep. 2016 Oct 4;6:34449. doi: 10.1038/srep34449.

17.

Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ.

Panciera T, Azzolin L, Fujimura A, Di Biagio D, Frasson C, Bresolin S, Soligo S, Basso G, Bicciato S, Rosato A, Cordenonsi M, Piccolo S.

Cell Stem Cell. 2016 Dec 1;19(6):725-737. doi: 10.1016/j.stem.2016.08.009. Epub 2016 Sep 15.

18.

Proteomic Alterations in Response to Hypoxia Inducible Factor 2α in Normoxic Neuroblastoma Cells.

Cimmino F, Pezone L, Avitabile M, Persano L, Vitale M, Sassi M, Bresolin S, Serafin V, Zambrano N, Scaloni A, Basso G, Iolascon A, Capasso M.

J Proteome Res. 2016 Oct 7;15(10):3643-3655. Epub 2016 Sep 28.

PMID:
27596920
19.

MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment.

Leoncini PP, Bertaina A, Papaioannou D, Flotho C, Masetti R, Bresolin S, Menna G, Santoro N, Zecca M, Basso G, Nigita G, Veneziano D, Pagotto S, D'Ovidio K, Rota R, Dorrance A, Croce CM, Niemeyer C, Locatelli F, Garzon R.

Oncotarget. 2016 Aug 23;7(34):55395-55408. doi: 10.18632/oncotarget.10577.

20.

Annexin 2A sustains glioblastoma cell dissemination and proliferation.

Maule F, Bresolin S, Rampazzo E, Boso D, Della Puppa A, Esposito G, Porcù E, Mitola S, Lombardi G, Accordi B, Tumino M, Basso G, Persano L.

Oncotarget. 2016 Aug 23;7(34):54632-54649. doi: 10.18632/oncotarget.10565.

21.

CREB engages C/EBPδ to initiate leukemogenesis.

Tregnago C, Manara E, Zampini M, Bisio V, Borga C, Bresolin S, Aveic S, Germano G, Basso G, Pigazzi M.

Leukemia. 2016 Sep;30(9):1887-96. doi: 10.1038/leu.2016.98. Epub 2016 Apr 27.

PMID:
27118402
22.

Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group.

Bresolin S, De Filippi P, Vendemini F, D'Alia M, Zecca M, Meyer LH, Danesino C, Locatelli F, Masetti R, Basso G, Te Kronnie G.

Oncotarget. 2016 May 17;7(20):28914-9. doi: 10.18632/oncotarget.8016.

23.

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

Helsmoortel HH, De Moerloose B, Pieters T, Ghazavi F, Bresolin S, Cavé H, de Vries A, de Haas V, Flotho C, Labarque V, Niemeyer C, De Paepe P, Van Roy N, Stary J, van den Heuvel-Eibrink MM, Benoit Y, Schulte J, Goossens S, Berx G, Haigh JJ, Speleman F, Van Vlierberghe P, Lammens T.

Haematologica. 2016 Jun;101(6):e240-4. doi: 10.3324/haematol.2016.143818. Epub 2016 Mar 11. No abstract available.

24.

GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia.

Guezguez B, Almakadi M, Benoit YD, Shapovalova Z, Rahmig S, Fiebig-Comyn A, Casado FL, Tanasijevic B, Bresolin S, Masetti R, Doble BW, Bhatia M.

Cancer Cell. 2016 Jan 11;29(1):61-74. doi: 10.1016/j.ccell.2015.11.012.

25.

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia.

Helsmoortel HH, Bresolin S, Lammens T, Cavé H, Noellke P, Caye A, Ghazavi F, de Vries A, Hasle H, Labarque V, Masetti R, Stary J, van den Heuvel-Eibrink MM, Philippé J, Van Roy N, Benoit Y, Speleman F, Niemeyer C, Flotho C, Basso G, Te Kronnie G, Van Vlierberghe P, De Moerloose B.

Blood. 2016 Mar 3;127(9):1163-72. doi: 10.1182/blood-2015-09-667808. Epub 2015 Dec 28.

26.

Aerobic glycolysis tunes YAP/TAZ transcriptional activity.

Enzo E, Santinon G, Pocaterra A, Aragona M, Bresolin S, Forcato M, Grifoni D, Pession A, Zanconato F, Guzzo G, Bicciato S, Dupont S.

EMBO J. 2015 May 12;34(10):1349-70. doi: 10.15252/embj.201490379. Epub 2015 Mar 21.

27.

Refinement of IKZF1 status in pediatric Philadelphia-positive acute lymphoblastic leukemia.

Lana T, de Lorenzo P, Bresolin S, Bronzini I, den Boer ML, Cavé H, Froňková E, Stanulla M, Zaliova M, Harrison CJ, de Groot H, Valsecchi MG, Biondi A, Basso G, Cazzaniga G, te Kronnie G.

Leukemia. 2015 Oct;29(10):2107-10. doi: 10.1038/leu.2015.78. Epub 2015 Mar 17. No abstract available.

PMID:
25778098
28.

Array-based comparative genomic hybridization analysis reveals chromosomal copy number aberrations associated with clinical outcome in canine diffuse large B-cell lymphoma.

Aricò A, Ferraresso S, Bresolin S, Marconato L, Comazzi S, Te Kronnie G, Aresu L.

PLoS One. 2014 Nov 5;9(11):e111817. doi: 10.1371/journal.pone.0111817. eCollection 2014.

29.

Low PKCα expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome.

Milani G, Rebora P, Accordi B, Galla L, Bresolin S, Cazzaniga G, Buldini B, Mura R, Ladogana S, Giraldi E, Conter V, Te Kronnie G, Valsecchi MG, Basso G.

Oncotarget. 2014 Jul 30;5(14):5234-45.

30.

YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response.

Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, Bresolin S, Frasson C, Basso G, Guzzardo V, Fassina A, Cordenonsi M, Piccolo S.

Cell. 2014 Jul 3;158(1):157-70. doi: 10.1016/j.cell.2014.06.013. Epub 2014 Jun 26.

31.

MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia.

Manara E, Baron E, Tregnago C, Aveic S, Bisio V, Bresolin S, Masetti R, Locatelli F, Basso G, Pigazzi M.

Blood. 2014 Jul 10;124(2):263-72. doi: 10.1182/blood-2013-09-525741. Epub 2014 Apr 2.

32.

Epigenetic silencing of TFPI-2 in canine diffuse large B-cell lymphoma.

Ferraresso S, Bresolin S, Aricò A, Comazzi S, Gelain ME, Riondato F, Bargelloni L, Marconato L, Kronnie Gt, Aresu L.

PLoS One. 2014 Apr 2;9(4):e92707. doi: 10.1371/journal.pone.0092707. eCollection 2014.

33.

Different outcomes of allogeneic hematopoietic stem cell transplant in a pair of twins affected by juvenile myelomonocytic leukemia.

Cesaro S, De Filippi P, Di Meglio A, Leszl A, Donska S, Zaccaron A, Cagioni C, Galavotti R, Danesino C, Aprili F, Cugno C, te Kronnie G, Zecca M, Bresolin S.

Int J Hematol. 2014 Feb;99(2):208-12. doi: 10.1007/s12185-013-1489-3. Epub 2013 Dec 12.

PMID:
24338706
34.

Validation of flow cytometric phospho-STAT5 as a diagnostic tool for juvenile myelomonocytic leukemia.

Hasegawa D, Bugarin C, Giordan M, Bresolin S, Longoni D, Micalizzi C, Ramenghi U, Bertaina A, Basso G, Locatelli F, Biondi A, Te Kronnie G, Gaipa G.

Blood Cancer J. 2013 Nov 15;3:e160. doi: 10.1038/bcj.2013.56.

35.

Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia.

Gandre-Babbe S, Paluru P, Aribeana C, Chou ST, Bresolin S, Lu L, Sullivan SK, Tasian SK, Weng J, Favre H, Choi JK, French DL, Loh ML, Weiss MJ.

Blood. 2013 Jun 13;121(24):4925-9. doi: 10.1182/blood-2013-01-478412. Epub 2013 Apr 25.

36.

Wnt activation promotes neuronal differentiation of glioblastoma.

Rampazzo E, Persano L, Pistollato F, Moro E, Frasson C, Porazzi P, Della Puppa A, Bresolin S, Battilana G, Indraccolo S, Te Kronnie G, Argenton F, Tiso N, Basso G.

Cell Death Dis. 2013 Feb 21;4:e500. doi: 10.1038/cddis.2013.32. Erratum in: Cell Death Dis. 2013;4:e597.

37.

Role of TAZ as mediator of Wnt signaling.

Azzolin L, Zanconato F, Bresolin S, Forcato M, Basso G, Bicciato S, Cordenonsi M, Piccolo S.

Cell. 2012 Dec 21;151(7):1443-56. doi: 10.1016/j.cell.2012.11.027. Epub 2012 Dec 13.

38.

MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation.

Pigazzi M, Manara E, Bresolin S, Tregnago C, Beghin A, Baron E, Giarin E, Cho EC, Masetti R, Rao DS, Sakamoto KM, Basso G.

Haematologica. 2013 Apr;98(4):602-10. doi: 10.3324/haematol.2012.070664. Epub 2012 Oct 25.

39.

Mesenchymal stem cells from Shwachman-Diamond syndrome patients display normal functions and do not contribute to hematological defects.

André V, Longoni D, Bresolin S, Cappuzzello C, Dander E, Galbiati M, Bugarin C, Di Meglio A, Nicolis E, Maserati E, Serafini M, Warren AJ, Te Kronnie G, Cazzaniga G, Sainati L, Cipolli M, Biondi A, D'Amico G.

Blood Cancer J. 2012 Oct 12;2:e94. doi: 10.1038/bcj.2012.40.

40.

Gene expression signatures of pediatric myelodysplastic syndromes are associated with risk of evolution into acute myeloid leukemia.

Bresolin S, Trentin L, Zecca M, Giordan M, Sainati L, Locatelli F, Basso G, te Kronnie G.

Leukemia. 2012 Jul;26(7):1717-9. doi: 10.1038/leu.2012.35. Epub 2012 Feb 7. No abstract available.

PMID:
22411123
41.

DNA methyltransferase 3a hot-spot locus is not mutated in pediatric patients affected by acute myeloid or T-cell acute lymphoblastic leukemia: an Italian study.

Paganin M, Pigazzi M, Bresolin S, Masetti R, Fagioli F, Chiaretti S, Cazzaniga G, Locatelli F, Pession A, te Kronnie G, Basso G.

Haematologica. 2011 Dec;96(12):1886-7. doi: 10.3324/haematol.2011.049825. Epub 2011 Aug 31. No abstract available.

42.

The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories.

Kohlmann A, Klein HU, Weissmann S, Bresolin S, Chaplin T, Cuppens H, Haschke-Becher E, Garicochea B, Grossmann V, Hanczaruk B, Hebestreit K, Gabriel C, Iacobucci I, Jansen JH, te Kronnie G, van de Locht L, Martinelli G, McGowan K, Schweiger MR, Timmermann B, Vandenberghe P, Young BD, Dugas M, Haferlach T.

Leukemia. 2011 Dec;25(12):1840-8. doi: 10.1038/leu.2011.155. Epub 2011 Jun 17.

PMID:
21681191
43.

Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia.

Montes R, Ayllón V, Gutierrez-Aranda I, Prat I, Hernández-Lamas MC, Ponce L, Bresolin S, Te Kronnie G, Greaves M, Bueno C, Menendez P.

Blood. 2011 May 5;117(18):4746-58. doi: 10.1182/blood-2010-12-322230. Epub 2011 Mar 9.

44.

MLL partner genes drive distinct gene expression profiles and genomic alterations in pediatric acute myeloid leukemia: an AIEOP study.

Pigazzi M, Masetti R, Bresolin S, Beghin A, Di Meglio A, Gelain S, Trentin L, Baron E, Giordan M, Zangrando A, Buldini B, Leszl A, Putti MC, Rizzari C, Locatelli F, Pession A, Te Kronnie G, Basso G.

Leukemia. 2011 Mar;25(3):560-3. doi: 10.1038/leu.2010.316. Epub 2011 Feb 18. No abstract available.

PMID:
21331072
45.

Gene expression-based classification as an independent predictor of clinical outcome in juvenile myelomonocytic leukemia.

Bresolin S, Zecca M, Flotho C, Trentin L, Zangrando A, Sainati L, Stary J, de Moerloose B, Hasle H, Niemeyer CM, Te Kronnie G, Locatelli F, Basso G.

J Clin Oncol. 2010 Apr 10;28(11):1919-27. doi: 10.1200/JCO.2009.24.4426. Epub 2010 Mar 15.

PMID:
20231685

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