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Items: 1 to 50 of 130

1.

Jack Aviv: Scientist, instrument wizard, humanist and philanthropist.

Breslauer KJ.

Biopolymers. 2018 Aug;109(8). doi: 10.1002/bip.23227. Epub 2018 Aug 9. No abstract available.

PMID:
30091453
2.

Impact of bistrand abasic sites and proximate orientation on DNA global structure and duplex energetics.

Minetti CA, Sun JY, Jacobs DP, Kang I, Remeta DP, Breslauer KJ.

Biopolymers. 2018 Aug;109(8):e23098. doi: 10.1002/bip.23098. Epub 2018 Jan 11.

3.

Impact of thymine glycol damage on DNA duplex energetics: Correlations with lesion-induced biochemical and structural consequences.

Minetti CA, Remeta DP, Iden CR, Johnson F, Grollman AP, Breslauer KJ.

Biopolymers. 2015 Sep;103(9):491-508. doi: 10.1002/bip.22680.

PMID:
25991500
4.

Conformational diversity of single-stranded DNA from bacterial repetitive extragenic palindromes: Implications for the DNA recognition elements of transposases.

Charnavets T, Nunvar J, Nečasová I, Völker J, Breslauer KJ, Schneider B.

Biopolymers. 2015 Oct;103(10):585-96. doi: 10.1002/bip.22666.

5.

APE1 incision activity at abasic sites in tandem repeat sequences.

Li M, Völker J, Breslauer KJ, Wilson DM 3rd.

J Mol Biol. 2014 May 29;426(11):2183-98. doi: 10.1016/j.jmb.2014.03.014. Epub 2014 Apr 1.

6.

Biopolymers celebrates 50 years of nucleic acids research.

Breslauer KJ, Case DA, Walter NG, Woodson SA.

Biopolymers. 2013 Dec;99(12):909. doi: 10.1002/bip.22358. No abstract available.

PMID:
23893377
7.

DNA meter: Energy tunable, quantitative hybridization assay.

Braunlin W, Völker J, Plum GE, Breslauer KJ.

Biopolymers. 2013 Jun;99(6):408-17. doi: 10.1002/bip.22213.

8.

Impact of bulge loop size on DNA triplet repeat domains: Implications for DNA repair and expansion.

Völker J, Plum GE, Gindikin V, Klump HH, Breslauer KJ.

Biopolymers. 2014 Jan;101(1):1-12. doi: 10.1002/bip.22236. Erratum in: Biopolymers. 2014 Apr;101(4):439.

9.

Energy landscapes of dynamic ensembles of rolling triplet repeat bulge loops: implications for DNA expansion associated with disease states.

Völker J, Gindikin V, Klump HH, Plum GE, Breslauer KJ.

J Am Chem Soc. 2012 Apr 4;134(13):6033-44. doi: 10.1021/ja3010896. Epub 2012 Mar 23.

10.

Novel post-synthetic generation, isomeric resolution, and characterization of Fapy-dG within oligodeoxynucleotides: differential anomeric impacts on DNA duplex properties.

Lukin M, Minetti CA, Remeta DP, Attaluri S, Johnson F, Breslauer KJ, de Los Santos C.

Nucleic Acids Res. 2011 Jul;39(13):5776-89. doi: 10.1093/nar/gkr082. Epub 2011 Mar 16.

11.

Energy crosstalk between DNA lesions: implications for allosteric coupling of DNA repair and triplet repeat expansion pathways.

Völker J, Plum GE, Klump HH, Breslauer KJ.

J Am Chem Soc. 2010 Mar 31;132(12):4095-7. doi: 10.1021/ja1002857.

12.

Energetic signatures of single base bulges: thermodynamic consequences and biological implications.

Minetti CA, Remeta DP, Dickstein R, Breslauer KJ.

Nucleic Acids Res. 2010 Jan;38(1):97-116. doi: 10.1093/nar/gkp1036. Epub 2009 Nov 27.

13.

Impact of alpha-hydroxy-propanodeoxyguanine adducts on DNA duplex energetics: opposite base modulation and implications for mutagenicity and genotoxicity.

Minetti CA, Remeta DP, Johnson F, Iden CR, Breslauer KJ.

Biopolymers. 2010 Apr;93(4):370-82. doi: 10.1002/bip.21355.

14.
15.

DNA repair and DNA triplet repeat expansion: the impact of abasic lesions on triplet repeat DNA energetics.

Völker J, Plum GE, Klump HH, Breslauer KJ.

J Am Chem Soc. 2009 Jul 8;131(26):9354-60. doi: 10.1021/ja902161e.

16.

Universal constant for heat production in protists.

Johnson MD, Völker J, Moeller HV, Laws E, Breslauer KJ, Falkowski PG.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6696-9. doi: 10.1073/pnas.0902005106. Epub 2009 Apr 3.

17.

DNA energy landscapes via calorimetric detection of microstate ensembles of metastable macrostates and triplet repeat diseases.

Völker J, Klump HH, Breslauer KJ.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18326-30. doi: 10.1073/pnas.0810376105. Epub 2008 Nov 17.

18.

A continuous hyperchromicity assay to characterize the kinetics and thermodynamics of DNA lesion recognition and base excision.

Minetti CA, Remeta DP, Breslauer KJ.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):70-5. doi: 10.1073/pnas.0710363105. Epub 2008 Jan 2.

19.

Structure and dynamics in DNA looped domains: CAG triplet repeat sequence dynamics probed by 2-aminopurine fluorescence.

Lee BJ, Barch M, Castner EW Jr, Völker J, Breslauer KJ.

Biochemistry. 2007 Sep 25;46(38):10756-66. Epub 2007 Aug 25.

PMID:
17718541
20.

DNA metastability and biological regulation: conformational dynamics of metastable omega-DNA bulge loops.

Völker J, Klump HH, Breslauer KJ.

J Am Chem Soc. 2007 Apr 25;129(16):5272-80. Epub 2007 Mar 31.

PMID:
17397164
21.

High resolution protein-DNA binding energy landscapes via a novel high throughput method.

Plum GE, Breslauer DN, Breslauer KJ.

Biopolymers. 2007 Apr 5-15;85(5-6):vii-viii. No abstract available.

PMID:
17366530
22.
23.

Julian Sturtevant: scientific giant, warm humanist, social activist, nature lover, gentle teacher, kind friend.

Breslauer KJ.

Biophys Chem. 2007 Mar;126(1-3):9-10. No abstract available.

PMID:
17330332
24.

What drives proteins into the major or minor grooves of DNA?

Privalov PL, Dragan AI, Crane-Robinson C, Breslauer KJ, Remeta DP, Minetti CA.

J Mol Biol. 2007 Jan 5;365(1):1-9. Epub 2006 Sep 27. Review.

25.

Hydration of diglycyl tripeptides with non-polar side chains: a volumetric study.

Chalikian TV, Gindikin VS, Breslauer KJ.

Biophys Chem. 1998 Oct 5;75(1):57-71.

PMID:
17027457
26.

Communication between noncontacting macromolecules.

Völker J, Breslauer KJ.

Annu Rev Biophys Biomol Struct. 2005;34:21-42. Review.

PMID:
15869382
28.

The thermodynamics of template-directed DNA synthesis: base insertion and extension enthalpies.

Minetti CA, Remeta DP, Miller H, Gelfand CA, Plum GE, Grollman AP, Breslauer KJ.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14719-24. Epub 2003 Nov 17.

29.

Energetics of lesion recognition by a DNA repair protein: thermodynamic characterization of formamidopyrimidine-glycosylase (Fpg) interactions with damaged DNA duplexes.

Minetti CA, Remeta DP, Zharkov DO, Plum GE, Johnson F, Grollman AP, Breslauer KJ.

J Mol Biol. 2003 May 16;328(5):1047-60.

PMID:
12729740
30.

Conformational energetics of stable and metastable states formed by DNA triplet repeat oligonucleotides: implications for triplet expansion diseases.

Völker J, Makube N, Plum GE, Klump HH, Breslauer KJ.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14700-5. Epub 2002 Nov 4.

31.
32.

Counterion association with native and denatured nucleic acids: an experimental approach.

Völker J, Klump HH, Manning GS, Breslauer KJ.

J Mol Biol. 2001 Jul 27;310(5):1011-25.

PMID:
11501992
33.

Communication between noncontacting macromolecules.

Völker J, Klump HH, Breslauer KJ.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7694-9.

34.
35.

Volumetric properties of nucleic acids.

Chalikian TV, Breslauer KJ.

Biopolymers. 1998;48(4):264-80. Review.

PMID:
10699844
36.

Effects of 3,N4-ethenodeoxycytidine on duplex stability and energetics.

Plum GE, Gelfand CA, Breslauer KJ.

IARC Sci Publ. 1999;(150):169-77. Review.

PMID:
10626218
37.

The hydration of nucleic acid duplexes as assessed by a combination of volumetric and structural techniques.

Chalikian TV, Völker J, Srinivasan AR, Olson WK, Breslauer KJ.

Biopolymers. 1999 Oct 15;50(5):459-71.

PMID:
10479730
38.

High-resolution calorimetric and optical melting profiles of DNA plasmids: resolving contributions from intrinsic melting domains and specifically designed inserts.

Völker J, Blake RD, Delcourt SG, Breslauer KJ.

Biopolymers. 1999 Sep;50(3):303-18. Erratum in: Biopolymers 2000 Jan;53(1):112.

PMID:
10397791
39.

A more unified picture for the thermodynamics of nucleic acid duplex melting: a characterization by calorimetric and volumetric techniques.

Chalikian TV, Völker J, Plum GE, Breslauer KJ.

Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7853-8.

40.

A quantitative method for evaluating the stabilities of nucleic acids.

Gelfand CA, Plum GE, Mielewczyk S, Remeta DP, Breslauer KJ.

Proc Natl Acad Sci U S A. 1999 May 25;96(11):6113-8.

41.

Tyrosine-PEG-derived poly(ether carbonate)s as new biomaterials. Part II: study of inverse temperature transitions.

Yu C, Mielewczyk SS, Breslauer KJ, Kohn J.

Biomaterials. 1999 Feb;20(3):265-72.

PMID:
10030603
42.

The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA.

Pilch DS, Poklar N, Baird EE, Dervan PB, Breslauer KJ.

Biochemistry. 1999 Feb 16;38(7):2143-51.

PMID:
10026298
43.

Thermodynamic analysis of biomolecules: a volumetric approach.

Chalikian TV, Breslauer KJ.

Curr Opin Struct Biol. 1998 Oct;8(5):657-64. Review.

PMID:
9818272
44.
45.

Thermodynamic consequences of an abasic lesion in duplex DNA are strongly dependent on base sequence.

Gelfand CA, Plum GE, Grollman AP, Johnson F, Breslauer KJ.

Biochemistry. 1998 May 19;37(20):7321-7.

PMID:
9585546
46.

DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles.

Xu Z, Li TK, Kim JS, LaVoie EJ, Breslauer KJ, Liu LF, Pilch DS.

Biochemistry. 1998 Mar 10;37(10):3558-66.

PMID:
9521677
47.

The native and the heat-induced denatured states of alpha-chymotrypsinogen A: thermodynamic and spectroscopic studies.

Chalikian TV, Völker J, Anafi D, Breslauer KJ.

J Mol Biol. 1997 Nov 28;274(2):237-52.

PMID:
9398530
48.
49.

Minor groove-directed and intercalative ligand-DNA interactions in the poisoning of human DNA topoisomerase I by protoberberine analogs.

Pilch DS, Yu C, Makhey D, LaVoie EJ, Srinivasan AR, Olson WK, Sauers RR, Breslauer KJ, Geacintov NE, Liu LF.

Biochemistry. 1997 Oct 14;36(41):12542-53.

PMID:
9376359
50.

Modulation of nucleic acid structure by ligand binding: induction of a DNA.RNA.DNA hybrid triplex by DAPI intercalation.

Xu Z, Pilch DS, Srinivasan AR, Olson WK, Geacintov NE, Breslauer KJ.

Bioorg Med Chem. 1997 Jun;5(6):1137-47.

PMID:
9222508

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