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Items: 42

1.

Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease.

Vezzoli E, Caron I, Talpo F, Besusso D, Conforti P, Battaglia E, Sogne E, Falqui A, Petricca L, Verani M, Martufi P, Caricasole A, Bresciani A, Cecchetti O, Rivetti di Val Cervo P, Sancini G, Riess O, Nguyen H, Seipold L, Saftig P, Biella G, Cattaneo E, Zuccato C.

J Clin Invest. 2019 May 6;130:2390-2403. doi: 10.1172/JCI120616. eCollection 2019 May 6.

2.

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides.

Bresciani A, Ontoria JM, Biancofiore I, Cellucci A, Ciammaichella A, Di Marco A, Ferrigno F, Francone A, Malancona S, Monteagudo E, Nizi E, Pace P, Ponzi S, Rossetti I, Veneziano M, Summa V, Harper S.

ACS Med Chem Lett. 2018 Nov 27;10(4):481-486. doi: 10.1021/acsmedchemlett.8b00517. eCollection 2019 Apr 11.

PMID:
30996783
3.

Fish-derived antimicrobial peptides: Activity of a chionodracine mutant against bacterial models and human bacterial pathogens.

Buonocore F, Picchietti S, Porcelli F, Della Pelle G, Olivieri C, Poerio E, Bugli F, Menchinelli G, Sanguinetti M, Bresciani A, Gennari N, Taddei AR, Fausto AM, Scapigliati G.

Dev Comp Immunol. 2019 Jul;96:9-17. doi: 10.1016/j.dci.2019.02.012. Epub 2019 Feb 18.

PMID:
30790604
4.

Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production.

Guidi A, Saccoccia F, Gennari N, Gimmelli R, Nizi E, Lalli C, Paonessa G, Papoff G, Bresciani A, Ruberti G.

Parasit Vectors. 2018 Dec 27;11(1):668. doi: 10.1186/s13071-018-3268-8.

5.

Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro.

Ferrigno F, Biancofiore I, Malancona S, Ponzi S, Paonessa G, Graziani R, Bresciani A, Gennari N, Di Marco A, Kaiser M, Summa V, Harper S, Ontoria JM.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3689-3692. doi: 10.1016/j.bmcl.2018.10.028. Epub 2018 Oct 22.

PMID:
30482621
6.

Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening.

Turcano L, Torrente E, Missineo A, Andreini M, Gramiccia M, Di Muccio T, Genovese I, Fiorillo A, Harper S, Bresciani A, Colotti G, Ilari A.

PLoS Negl Trop Dis. 2018 Nov 26;12(11):e0006969. doi: 10.1371/journal.pntd.0006969. eCollection 2018 Nov.

7.

Development of a Broadly Applicable Assay for Measurement of Glycan-Directed Enzymatic Activity.

Bresciani A, Cecchetti O, Missineo A, Pacifici PG, Tomei L, Rodems S.

SLAS Discov. 2018 Oct;23(9):941-950. doi: 10.1177/2472555218782625. Epub 2018 Jun 22.

PMID:
29932789
8.

Peptidomimetic nitrile inhibitors of malarial protease falcipain-2 with high selectivity against human cathepsins.

Nizi E, Sferrazza A, Fabbrini D, Nardi V, Andreini M, Graziani R, Gennari N, Bresciani A, Paonessa G, Harper S.

Bioorg Med Chem Lett. 2018 May 15;28(9):1540-1544. doi: 10.1016/j.bmcl.2018.03.069. Epub 2018 Mar 26.

PMID:
29615344
9.

Quantifying autophagy using novel LC3B and p62 TR-FRET assays.

Bresciani A, Spiezia MC, Boggio R, Cariulo C, Nordheim A, Altobelli R, Kuhlbrodt K, Dominguez C, Munoz-Sanjuan I, Wityak J, Fodale V, Marchionini DM, Weiss A.

PLoS One. 2018 Mar 19;13(3):e0194423. doi: 10.1371/journal.pone.0194423. eCollection 2018.

10.

Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay.

Fodale V, Boggio R, Daldin M, Cariulo C, Spiezia MC, Byrne LM, Leavitt BR, Wild EJ, Macdonald D, Weiss A, Bresciani A.

J Huntingtons Dis. 2017;6(4):349-361. doi: 10.3233/JHD-170269.

11.

Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome.

Lania G, Bresciani A, Bisbocci M, Francone A, Colonna V, Altamura S, Baldini A.

Hum Mol Genet. 2017 Nov 15;26(22):4540. doi: 10.1093/hmg/ddx353. No abstract available.

12.

Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.

Guidi A, Lalli C, Gimmelli R, Nizi E, Andreini M, Gennari N, Saccoccia F, Harper S, Bresciani A, Ruberti G.

PLoS Negl Trop Dis. 2017 Oct 6;11(10):e0005994. doi: 10.1371/journal.pntd.0005994. eCollection 2017 Oct.

13.

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).

Bresciani A, Missineo A, Gallo M, Cerretani M, Fezzardi P, Tomei L, Cicero DO, Altamura S, Santoprete A, Ingenito R, Bianchi E, Pacifici R, Dominguez C, Munoz-Sanjuan I, Harper S, Toledo-Sherman L, Park LC.

Arch Biochem Biophys. 2017 Oct 1;631:31-41. doi: 10.1016/j.abb.2017.08.003. Epub 2017 Aug 8. Review.

PMID:
28801166
14.

Polyglutamine expansion affects huntingtin conformation in multiple Huntington's disease models.

Daldin M, Fodale V, Cariulo C, Azzollini L, Verani M, Martufi P, Spiezia MC, Deguire SM, Cherubini M, Macdonald D, Weiss A, Bresciani A, Vonsattel JG, Petricca L, Marsh JL, Gines S, Santimone I, Marano M, Lashuel HA, Squitieri F, Caricasole A.

Sci Rep. 2017 Jul 11;7(1):5070. doi: 10.1038/s41598-017-05336-7.

15.

Identification by High-Throughput Screening of Pseudomonas Acyl-Coenzyme A Synthetase Inhibitors.

Turcano L, Visaggio D, Frangipani E, Missineo A, Andreini M, Altamura S, Visca P, Bresciani A.

SLAS Discov. 2017 Aug;22(7):897-905. doi: 10.1177/2472555216689283. Epub 2017 Jan 31.

PMID:
28346095
16.

Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome.

Lania G, Bresciani A, Bisbocci M, Francone A, Colonna V, Altamura S, Baldini A.

Hum Mol Genet. 2016 Oct 15;25(20):4369-4375. doi: 10.1093/hmg/ddw267. Erratum in: Hum Mol Genet. 2017 Nov 15;26(22):4540.

17.

Corrigendum: The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota.

Lagkouvardos I, Pukall R, Abt B, Foesel BU, Meier-Kolthoff JP, Kumar N, Bresciani A, Martínez I, Just S, Ziegler C, Brugiroux S, Garzetti D, Wenning M, Bui TP, Wang J, Hugenholtz F, Plugge CM, Peterson DA, Hornef MW, Baines JF, Smidt H, Walter J, Kristiansen K, Nielsen HB, Haller D, Overmann J, Stecher B, Clavel T.

Nat Microbiol. 2016 Oct 17;1(11):16219. doi: 10.1038/nmicrobiol.2016.219. No abstract available.

PMID:
27748770
18.

The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota.

Lagkouvardos I, Pukall R, Abt B, Foesel BU, Meier-Kolthoff JP, Kumar N, Bresciani A, Martínez I, Just S, Ziegler C, Brugiroux S, Garzetti D, Wenning M, Bui TP, Wang J, Hugenholtz F, Plugge CM, Peterson DA, Hornef MW, Baines JF, Smidt H, Walter J, Kristiansen K, Nielsen HB, Haller D, Overmann J, Stecher B, Clavel T.

Nat Microbiol. 2016 Aug 8;1(10):16131. doi: 10.1038/nmicrobiol.2016.131. Erratum in: Nat Microbiol. 2016 Oct 17;1(11):16219.

PMID:
27670113
19.

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems.

Guidi A, Lalli C, Perlas E, Bolasco G, Nibbio M, Monteagudo E, Bresciani A, Ruberti G.

PLoS Negl Trop Dis. 2016 Aug 12;10(8):e0004928. doi: 10.1371/journal.pntd.0004928. eCollection 2016 Aug.

20.

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.

Ontoria JM, Paonessa G, Ponzi S, Ferrigno F, Nizi E, Biancofiore I, Malancona S, Graziani R, Roberts D, Willis P, Bresciani A, Gennari N, Cecchetti O, Monteagudo E, Orsale MV, Veneziano M, Di Marco A, Cellucci A, Laufer R, Altamura S, Summa V, Harper S.

ACS Med Chem Lett. 2016 Mar 5;7(5):454-9. doi: 10.1021/acsmedchemlett.5b00468. eCollection 2016 May 12.

21.

T-cell recognition is shaped by epitope sequence conservation in the host proteome and microbiome.

Bresciani A, Paul S, Schommer N, Dillon MB, Bancroft T, Greenbaum J, Sette A, Nielsen M, Peters B.

Immunology. 2016 May;148(1):34-9. doi: 10.1111/imm.12585. Epub 2016 Feb 8.

22.

Carotid artery diameter and wall stiffness in proteinuric renal disease without severely reduced kidney function.

Iannuzzi M, D'Angelillo A, Tortori A, Pazzano D, De Serio L, Covetti G, Bresciani A, Iannuzzi A.

J Clin Ultrasound. 2016 Mar-Apr;44(3):175-81. doi: 10.1002/jcu.22292. Epub 2015 Sep 24.

PMID:
26402850
23.

Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin.

Finotti A, Gasparello J, Breveglieri G, Cosenza LC, Montagner G, Bresciani A, Altamura S, Bianchi N, Martini E, Gallerani E, Borgatti M, Gambari R.

Exp Hematol. 2015 Dec;43(12):1062-1071.e3. doi: 10.1016/j.exphem.2015.08.011. Epub 2015 Sep 3.

24.

Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni.

Lalli C, Guidi A, Gennari N, Altamura S, Bresciani A, Ruberti G.

PLoS Negl Trop Dis. 2015 Jan 30;9(1):e0003484. doi: 10.1371/journal.pntd.0003484. eCollection 2015 Jan.

25.

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells.

Montagner G, Gemmo C, Fabbri E, Manicardi A, Accardo I, Bianchi N, Finotti A, Breveglieri G, Salvatori F, Borgatti M, Lampronti I, Bresciani A, Altamura S, Corradini R, Gambari R.

Int J Mol Med. 2015 Jan;35(1):51-8. doi: 10.3892/ijmm.2014.2005. Epub 2014 Nov 14.

26.

Medication non-adherence among elderly patients newly discharged and receiving polypharmacy.

Pasina L, Brucato AL, Falcone C, Cucchi E, Bresciani A, Sottocorno M, Taddei GC, Casati M, Franchi C, Djade CD, Nobili A.

Drugs Aging. 2014 Apr;31(4):283-9. doi: 10.1007/s40266-014-0163-7.

PMID:
24604085
27.

Peri-procedural tight glycemic control during early percutaneous coronary intervention is associated with a lower rate of in-stent restenosis in patients with acute ST-elevation myocardial infarction.

Marfella R, Sasso FC, Siniscalchi M, Paolisso P, Rizzo MR, Ferraro F, Stabile E, Sorropago G, Calabrò P, Carbonara O, Cinquegrana G, Piscione F, Ruocco A, D'Andrea D, Rapacciuolo A, Petronella P, Bresciani A, Rubino P, Mauro C, Paolisso G.

J Clin Endocrinol Metab. 2012 Aug;97(8):2862-71. doi: 10.1210/jc.2012-1364. Epub 2012 May 25.

PMID:
22639289
28.

A novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins.

Grifantini R, Pagani M, Pierleoni A, Grandi A, Parri M, Campagnoli S, Pileri P, Cattaneo D, Canidio E, Pontillo A, De Camilli E, Bresciani A, Marinoni F, Pedrazzoli E, Nogarotto R, Abrignani S, Viale G, Sarmientos P, Grandi G.

J Proteomics. 2011 Dec 21;75(2):532-47. doi: 10.1016/j.jprot.2011.08.018. Epub 2011 Sep 5.

PMID:
21920474
29.

Identification of a series of 4-[3-(quinolin-2-yl)-1,2,4-oxadiazol-5-yl]piperazinyl ureas as potent smoothened antagonist hedgehog pathway inhibitors.

Ontoria JM, Bufi LL, Torrisi C, Bresciani A, Giomini C, Rowley M, Serafini S, Bin H, Hao W, Steinkühler C, Jones P.

Bioorg Med Chem Lett. 2011 Sep 15;21(18):5274-82. doi: 10.1016/j.bmcl.2011.07.031. Epub 2011 Jul 14.

PMID:
21803580
30.

N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists.

Muraglia E, Ontoria JM, Branca D, Dessole G, Bresciani A, Fonsi M, Giuliano C, Llauger Bufi L, Monteagudo E, Palumbi MC, Torrisi C, Rowley M, Steinkühler C, Jones P.

Bioorg Med Chem Lett. 2011 Sep 15;21(18):5283-8. doi: 10.1016/j.bmcl.2011.07.030. Epub 2011 Jul 14.

PMID:
21802943
31.

Rhombencephalitis caused by Listeria monocytogenes with striking involvement of trigeminal nerve on MR imaging.

Moro A, Albino PH, Bresciani AP, Oliveira MV, Bertotti MM, Ferreira RM, Queiroz LP.

Arq Neuropsiquiatr. 2011 Jun;69(3):568-9. No abstract available.

32.

Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis.

Fortugno P, Bresciani A, Paolini C, Pazzagli C, El Hachem M, D'Alessio M, Zambruno G.

J Invest Dermatol. 2011 Nov;131(11):2223-32. doi: 10.1038/jid.2011.174. Epub 2011 Jun 23.

33.

Comparison of two diets of varying glycemic index on carotid subclinical atherosclerosis in obese children.

Iannuzzi A, Licenziati MR, Vacca M, De Marco D, Cinquegrana G, Laccetti M, Bresciani A, Covetti G, Iannuzzo G, Rubba P, Parillo M.

Heart Vessels. 2009 Nov;24(6):419-24. doi: 10.1007/s00380-008-1138-6. Epub 2009 Nov 22.

PMID:
20108073
34.

Carotid artery wall hypertrophy in children with metabolic syndrome.

Iannuzzi A, Licenziati MR, Acampora C, De Michele M, Iannuzzo G, Chiariello G, Covetti G, Bresciani A, Romano L, Panico S, Rubba P.

J Hum Hypertens. 2008 Feb;22(2):83-8. Epub 2007 Oct 11.

PMID:
17928879
35.

Increased serum concentrations of soluble HLA-class I antigens in hepatitis C virus related mixed cryoglobulinaemia.

Migliaresi S, Bresciani A, Ambrosone L, Spera M, Barbarulo D, Lombari V, Pirozzi G, Borgia G, Lombardi ML, Tirri G, Manzo C.

Ann Rheum Dis. 2000 Jan;59(1):20-5.

36.

Increased level of serum HLA class I antigens in patients with systemic lupus in patients with systemic lupus erythematosus. Correlation with disease activity.

Bresciani A, Pirozzi G, Spera M, Lombardi ML, Ambrosone L, Migliaresi S, Ferrone S, Manzo C.

Tissue Antigens. 1998 Jul;52(1):44-50.

PMID:
9714473
37.

Vibrio cholerae 01 isolated in the gallbladder of a patient presenting with cholecystitis.

Asnis DS, Golub R, Bresciani A.

Am J Gastroenterol. 1996 Oct;91(10):2241-2.

PMID:
8855762
38.
39.

Light and electron microscopic identification of Cyclospora species in the small intestine. Evidence of the presence of asexual life cycle in human host.

Sun T, Ilardi CF, Asnis D, Bresciani AR, Goldenberg S, Roberts B, Teichberg S.

Am J Clin Pathol. 1996 Feb;105(2):216-20.

PMID:
8607448
40.

Cost-effective approach to evaluation of diarrheal illness in hospitals.

Asnis DS, Bresciani A, Ryan M, McArdle P, Mollura JL, Ilardi CF.

J Clin Microbiol. 1993 Jun;31(6):1675. No abstract available.

41.

Cutaneous tuberculosis: a rare presentation of malignancy.

Asnis DS, Bresciani AR.

Clin Infect Dis. 1992 Jul;15(1):158-60.

PMID:
1617055
42.

Bacteremia due to Erysipelothrix rhusiopathiae.

Asnis DS, Bresciani AR.

South Med J. 1992 Mar;85(3):332-3. No abstract available.

PMID:
1546365

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