Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 131

1.

Ca(II) and Zn(II) Cooperate To Modulate the Structure and Self-Assembly of S100A12.

Wang Q, Aleshintsev A, Bolton D, Zhuang J, Brenowitz M, Gupta R.

Biochemistry. 2019 Apr 30;58(17):2269-2281. doi: 10.1021/acs.biochem.9b00123. Epub 2019 Apr 18.

PMID:
30957488
2.

Chemical Generation of Hydroxyl Radical for Oxidative 'Footprinting'.

Leser M, Chapman JR, Khine M, Pegan J, Law M, Makkaoui ME, Ueberheide BM, Brenowitz M.

Protein Pept Lett. 2019;26(1):61-69. doi: 10.2174/0929866526666181212164812. Review.

PMID:
30543161
3.

Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release.

Warren C, Matsui T, Karp JM, Onikubo T, Cahill S, Brenowitz M, Cowburn D, Girvin M, Shechter D.

Nat Commun. 2017 Dec 20;8(1):2215. doi: 10.1038/s41467-017-02308-3.

4.

Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module.

Ghosh A, Ramagopal UA, Bonanno JB, Brenowitz M, Almo SC.

Biochemistry. 2018 Feb 27;57(8):1293-1305. doi: 10.1021/acs.biochem.7b01074. Epub 2018 Feb 7.

5.

An Opportunity for Industry-Academia Partnership: Training the Next Generation of Industrial Researchers in Characterizing Higher Order Protein Structure.

Bain DL, Brenowitz M, Roberts CJ.

J Pharm Sci. 2016 Dec;105(12):3483-3486. doi: 10.1016/j.xphs.2016.08.007. Epub 2016 Sep 23. Review.

PMID:
27671238
6.

Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging.

Shcherbakova DM, Baloban M, Emelyanov AV, Brenowitz M, Guo P, Verkhusha VV.

Nat Commun. 2016 Aug 19;7:12405. doi: 10.1038/ncomms12405.

7.

MeCP2 Binding Cooperativity Inhibits DNA Modification-Specific Recognition.

Khrapunov S, Tao Y, Cheng H, Padlan C, Harris R, Galanopoulou AS, Greally JM, Girvin ME, Brenowitz M.

Biochemistry. 2016 Aug 9;55(31):4275-85. doi: 10.1021/acs.biochem.6b00451. Epub 2016 Jul 28.

8.

Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer.

LoPiccolo J, Kim SJ, Shi Y, Wu B, Wu H, Chait BT, Singer RH, Sali A, Brenowitz M, Bresnick AR, Backer JM.

J Biol Chem. 2015 Dec 18;290(51):30390-405. doi: 10.1074/jbc.M115.689604. Epub 2015 Oct 16.

9.

Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity.

Shymanets A, Prajwal, Vadas O, Czupalla C, LoPiccolo J, Brenowitz M, Ghigo A, Hirsch E, Krause E, Wetzker R, Williams RL, Harteneck C, Nürnberg B.

Biochem J. 2015 Jul 1;469(1):59-69. doi: 10.1042/BJ20150099.

10.

Structural and Functional Studies on the Marburg Virus GP2 Fusion Loop.

Liu N, Tao Y, Brenowitz MD, Girvin ME, Lai JR.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S146-53. doi: 10.1093/infdis/jiv030. Epub 2015 Mar 18.

11.

Protein footprinting by pyrite shrink-wrap laminate.

Leser M, Pegan J, El Makkaoui M, Schlatterer JC, Khine M, Law M, Brenowitz M.

Lab Chip. 2015 Apr 7;15(7):1646-50. doi: 10.1039/c4lc01288g.

PMID:
25666234
12.

Conditional trimerization and lytic activity of HIV-1 gp41 variants containing the membrane-associated segments.

Dai Z, Tao Y, Liu N, Brenowitz MD, Girvin ME, Lai JR.

Biochemistry. 2015 Mar 3;54(8):1589-99. doi: 10.1021/bi501376f. Epub 2015 Feb 13.

13.

Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity.

Khrapunov S, Warren C, Cheng H, Berko ER, Greally JM, Brenowitz M.

Biochemistry. 2014 Jun 3;53(21):3379-91. doi: 10.1021/bi500424z. Epub 2014 May 23.

14.

Mapping the kinetic barriers of a Large RNA molecule's folding landscape.

Schlatterer JC, Martin JS, Laederach A, Brenowitz M.

PLoS One. 2014 Feb 25;9(2):e85041. doi: 10.1371/journal.pone.0085041. eCollection 2014.

15.

An RNA aptamer possessing a novel monovalent cation-mediated fold inhibits lysozyme catalysis by inhibiting the binding of long natural substrates.

Padlan CS, Malashkevich VN, Almo SC, Levy M, Brenowitz M, Girvin ME.

RNA. 2014 Apr;20(4):447-61. doi: 10.1261/rna.043034.113. Epub 2014 Feb 25.

16.

Structure of the S100A4/myosin-IIA complex.

Ramagopal UA, Dulyaninova NG, Varney KM, Wilder PT, Nallamsetty S, Brenowitz M, Weber DJ, Almo SC, Bresnick AR.

BMC Struct Biol. 2013 Nov 20;13:31. doi: 10.1186/1472-6807-13-31.

17.

Understanding the role of three-dimensional topology in determining the folding intermediates of group I introns.

Chen C, Mitra S, Jonikas M, Martin J, Brenowitz M, Laederach A.

Biophys J. 2013 Mar 19;104(6):1326-37. doi: 10.1016/j.bpj.2013.02.007. Epub 2013 Mar 19.

18.

Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.

Ho MC, Wilczek C, Bonanno JB, Xing L, Seznec J, Matsui T, Carter LG, Onikubo T, Kumar PR, Chan MK, Brenowitz M, Cheng RH, Reimer U, Almo SC, Shechter D.

PLoS One. 2013;8(2):e57008. doi: 10.1371/journal.pone.0057008. Epub 2013 Feb 25. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/e6b5348e-9052-4a3b-8f06-90d01dc88fc2.

19.

Conformational heterogeneity of the protein-free human spliceosomal U2-U6 snRNA complex.

Zhao C, Bachu R, Popovic M, Devany M, Brenowitz M, Schlatterer JC, Greenbaum NL.

RNA. 2013 Apr;19(4):561-73. doi: 10.1261/rna.038265.113. Epub 2013 Feb 20.

20.

Pyrite footprinting of RNA.

Schlatterer JC, Wieder MS, Jones CD, Pollack L, Brenowitz M.

Biochem Biophys Res Commun. 2012 Aug 24;425(2):374-8. doi: 10.1016/j.bbrc.2012.07.100. Epub 2012 Jul 27.

PMID:
22842460
21.

Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control.

Patel VL, Mitra S, Harris R, Buxbaum AR, Lionnet T, Brenowitz M, Girvin M, Levy M, Almo SC, Singer RH, Chao JA.

Genes Dev. 2012 Jan 1;26(1):43-53. doi: 10.1101/gad.177428.111.

22.

Monitoring equilibrium changes in RNA structure by 'peroxidative' and 'oxidative' hydroxyl radical footprinting.

Bachu R, Padlan FC, Rouhanifard S, Brenowitz M, Schlatterer JC.

J Vis Exp. 2011 Oct 17;(56):e3244. doi: 10.3791/3244.

23.

Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.

Guan R, Ho MC, Brenowitz M, Tyler PC, Evans GB, Almo SC, Schramm VL.

Biochemistry. 2011 Nov 29;50(47):10408-17. doi: 10.1021/bi201321x. Epub 2011 Nov 7.

24.

A microfluidic device that generates hydroxyl radicals to probe the solvent accessible surface of nucleic acids.

Jones CD, Schlatterer JC, Brenowitz M, Pollack L.

Lab Chip. 2011 Oct 21;11(20):3458-64. doi: 10.1039/c1lc20280d. Epub 2011 Aug 24.

PMID:
21863183
25.

Introduction: twenty five years of the Gibbs Conference on Biothermodynamics.

Shea MA, Correia JJ, Brenowitz MD.

Biophys Chem. 2011 Nov;159(1):1-5. doi: 10.1016/j.bpc.2011.07.002. Epub 2011 Jul 21.

PMID:
21840113
26.

RNA molecules with conserved catalytic cores but variable peripheries fold along unique energetically optimized pathways.

Mitra S, Laederach A, Golden BL, Altman RB, Brenowitz M.

RNA. 2011 Aug;17(8):1589-603. doi: 10.1261/rna.2694811. Epub 2011 Jun 28.

27.

Stability, denaturation and refolding of Mycobacterium tuberculosis MfpA, a DNA mimicking protein that confers antibiotic resistance.

Khrapunov S, Brenowitz M.

Biophys Chem. 2011 Nov;159(1):33-40. doi: 10.1016/j.bpc.2011.04.015. Epub 2011 May 5.

28.

Decoy strategies: the structure of TL1A:DcR3 complex.

Zhan C, Patskovsky Y, Yan Q, Li Z, Ramagopal U, Cheng H, Brenowitz M, Hui X, Nathenson SG, Almo SC.

Structure. 2011 Feb 9;19(2):162-71. doi: 10.1016/j.str.2010.12.004.

29.

Phenothiazines inhibit S100A4 function by inducing protein oligomerization.

Malashkevich VN, Dulyaninova NG, Ramagopal UA, Liriano MA, Varney KM, Knight D, Brenowitz M, Weber DJ, Almo SC, Bresnick AR.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8605-10. doi: 10.1073/pnas.0913660107. Epub 2010 Apr 26.

30.

Conformational states of human purine nucleoside phosphorylase at rest, at work, and with transition state analogues.

Edwards AA, Tipton JD, Brenowitz MD, Emmett MR, Marshall AG, Evans GB, Tyler PC, Schramm VL.

Biochemistry. 2010 Mar 9;49(9):2058-67. doi: 10.1021/bi902041j.

31.

Biochemical and structural characterization of the human TL1A ectodomain.

Zhan C, Yan Q, Patskovsky Y, Li Z, Toro R, Meyer A, Cheng H, Brenowitz M, Nathenson SG, Almo SC.

Biochemistry. 2009 Aug 18;48(32):7636-45. doi: 10.1021/bi900031w.

32.

Complementing global measures of RNA folding with local reports of backbone solvent accessibility by time resolved hydroxyl radical footprinting.

Schlatterer JC, Brenowitz M.

Methods. 2009 Oct;49(2):142-7. doi: 10.1016/j.ymeth.2009.04.019. Epub 2009 May 6.

33.

Evolutionary and biophysical relationships among the papillomavirus E2 proteins.

Blakaj DM, Fernandez-Fuentes N, Chen Z, Hegde R, Fiser A, Burk RD, Brenowitz M.

Front Biosci (Landmark Ed). 2009 Jan 1;14:900-17. Review.

34.

PEGylation of Val-1(alpha) destabilizes the tetrameric structure of hemoglobin.

Hu T, Li D, Manjula BN, Brenowitz M, Prabhakaran M, Acharya SA.

Biochemistry. 2009 Jan 27;48(3):608-16. doi: 10.1021/bi801880y.

PMID:
19119852
35.

Solution structure and refolding of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA.

Khrapunov S, Cheng H, Hegde S, Blanchard J, Brenowitz M.

J Biol Chem. 2008 Dec 26;283(52):36290-9. doi: 10.1074/jbc.M804702200. Epub 2008 Oct 31.

36.

Energy barriers, pathways, and dynamics during folding of large, multidomain RNAs.

Shcherbakova I, Mitra S, Laederach A, Brenowitz M.

Curr Opin Chem Biol. 2008 Dec;12(6):655-66. doi: 10.1016/j.cbpa.2008.09.017. Epub 2008 Oct 14. Review.

37.

Semiautomated and rapid quantification of nucleic acid footprinting and structure mapping experiments.

Laederach A, Das R, Vicens Q, Pearlman SM, Brenowitz M, Herschlag D, Altman RB.

Nat Protoc. 2008;3(9):1395-401. doi: 10.1038/nprot.2008.134.

38.

Function and structural organization of Mot1 bound to a natural target promoter.

Sprouse RO, Shcherbakova I, Cheng H, Jamison E, Brenowitz M, Auble DT.

J Biol Chem. 2008 Sep 5;283(36):24935-48. doi: 10.1074/jbc.M803749200. Epub 2008 Jul 7.

39.

High-throughput single-nucleotide structural mapping by capillary automated footprinting analysis.

Mitra S, Shcherbakova IV, Altman RB, Brenowitz M, Laederach A.

Nucleic Acids Res. 2008 Jun;36(11):e63. doi: 10.1093/nar/gkn267. Epub 2008 May 13.

40.

Hinge stiffness is a barrier to RNA folding.

Schlatterer JC, Kwok LW, Lamb JS, Park HY, Andresen K, Brenowitz M, Pollack L.

J Mol Biol. 2008 Jun 13;379(4):859-70. doi: 10.1016/j.jmb.2008.04.013. Epub 2008 Apr 10.

41.

Time-resolved hydroxyl radical footprinting of RNA with X-rays.

Woodson SA, Deras ML, Brenowitz M.

Curr Protoc Nucleic Acid Chem. 2001 Nov;Chapter 11:Unit 11.6. doi: 10.1002/0471142700.nc1106s06.

PMID:
18428832
42.
43.

DNase I footprint analysis of protein-DNA binding.

Brenowitz M, Senear DF, Kingston RE.

Curr Protoc Mol Biol. 2001 May;Chapter 12:Unit 12.4. doi: 10.1002/0471142727.mb1204s07.

PMID:
18265087
44.

Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.

Chattopadhyay K, Ramagopal UA, Brenowitz M, Nathenson SG, Almo SC.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):635-40. doi: 10.1073/pnas.0710529105. Epub 2008 Jan 8.

45.

Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.

Chattopadhyay K, Ramagopal UA, Mukhopadhaya A, Malashkevich VN, Dilorenzo TP, Brenowitz M, Nathenson SG, Almo SC.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19452-7. Epub 2007 Nov 26.

46.

Following molecular transitions with single residue spatial and millisecond time resolution.

Shcherbakova I, Mitra S, Beer RH, Brenowitz M.

Methods Cell Biol. 2008;84:589-615.

PMID:
17964944
47.

DNA and protein footprinting analysis of the modulation of DNA binding by the N-terminal domain of the Saccharomyces cerevisiae TATA binding protein.

Gupta S, Cheng H, Mollah AK, Jamison E, Morris S, Chance MR, Khrapunov S, Brenowitz M.

Biochemistry. 2007 Sep 4;46(35):9886-98. Epub 2007 Aug 7.

PMID:
17683121
48.

Distinct contribution of electrostatics, initial conformational ensemble, and macromolecular stability in RNA folding.

Laederach A, Shcherbakova I, Jonikas MA, Altman RB, Brenowitz M.

Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7045-50. Epub 2007 Apr 16.

49.
50.

Binding then bending: a mechanism for wrapping DNA.

Khrapunov S, Brenowitz M, Rice PA, Catalano CE.

Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19217-8. Epub 2006 Dec 11. No abstract available.

Supplemental Content

Loading ...
Support Center