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Items: 1 to 50 of 57

1.

Substrate priming enhances phosphorylation by the budding yeast kinases Kin1 and Kin2.

Jeschke GR, Lou HJ, Weise K, Hammond CI, Demonch M, Brennwald P, Turk BE.

J Biol Chem. 2018 Nov 23;293(47):18353-18364. doi: 10.1074/jbc.RA118.005651. Epub 2018 Oct 10.

PMID:
30305396
2.

The tomosyn homologue, Sro7, is a direct effector of the Rab GTPase, Sec4, in post-Golgi vesicle tethering.

Rossi G, Watson K, Kennedy W, Brennwald P.

Mol Biol Cell. 2018 Jun 15;29(12):1476-1486. doi: 10.1091/mbc.E18-02-0138. Epub 2018 Apr 18.

3.

An evidence-based evaluation of transferrable skills and job satisfaction for science PhDs.

Sinche M, Layton RL, Brandt PD, O'Connell AB, Hall JD, Freeman AM, Harrell JR, Cook JG, Brennwald PJ.

PLoS One. 2017 Sep 20;12(9):e0185023. doi: 10.1371/journal.pone.0185023. eCollection 2017.

4.

Structural basis for recognition of the Sec4 Rab GTPase by its effector, the Lgl/tomosyn homologue, Sro7.

Watson K, Rossi G, Temple B, Brennwald P.

Mol Biol Cell. 2015 Sep 15;26(18):3289-300. doi: 10.1091/mbc.E15-04-0228. Epub 2015 Jul 22.

5.

In vitro reconstitution of Rab GTPase-dependent vesicle clustering by the yeast lethal giant larvae/tomosyn homolog, Sro7.

Rossi G, Watson K, Demonch M, Temple B, Brennwald P.

J Biol Chem. 2015 Jan 2;290(1):612-24. doi: 10.1074/jbc.M114.595892. Epub 2014 Nov 17.

6.

Quantitative analysis of membrane trafficking in regulation of Cdc42 polarity.

Watson LJ, Rossi G, Brennwald P.

Traffic. 2014 Dec;15(12):1330-43. doi: 10.1111/tra.12211. Epub 2014 Oct 8.

7.

Membrane traffic: the exocyst meets the cell cycle.

Brennwald P.

Curr Biol. 2013 Sep 23;23(18):R838-40. doi: 10.1016/j.cub.2013.08.007.

8.

Quantitative proteomics of yeast post-Golgi vesicles reveals a discriminating role for Sro7p in protein secretion.

Forsmark A, Rossi G, Wadskog I, Brennwald P, Warringer J, Adler L.

Traffic. 2011 Jun;12(6):740-53. doi: 10.1111/j.1600-0854.2011.01186.x. Epub 2011 Apr 8.

9.

Yeast homologues of lethal giant larvae and type V myosin cooperate in the regulation of Rab-dependent vesicle clustering and polarized exocytosis.

Rossi G, Brennwald P.

Mol Biol Cell. 2011 Mar 15;22(6):842-57. doi: 10.1091/mbc.E10-07-0570. Epub 2011 Jan 19.

10.

The function of two Rho family GTPases is determined by distinct patterns of cell surface localization.

Wu H, Brennwald P.

Mol Cell Biol. 2010 Nov;30(21):5207-17. doi: 10.1128/MCB.00366-10. Epub 2010 Sep 7.

11.

Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1.

Boulter E, Garcia-Mata R, Guilluy C, Dubash A, Rossi G, Brennwald PJ, Burridge K.

Nat Cell Biol. 2010 May;12(5):477-83. doi: 10.1038/ncb2049. Epub 2010 Apr 18.

12.

Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium.

Ivanov AI, Young C, Den Beste K, Capaldo CT, Humbert PO, Brennwald P, Parkos CA, Nusrat A.

Am J Pathol. 2010 Jan;176(1):134-45. doi: 10.2353/ajpath.2010.090220. Epub 2009 Dec 3.

13.

The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis.

Wu H, Turner C, Gardner J, Temple B, Brennwald P.

Mol Biol Cell. 2010 Feb 1;21(3):430-42. doi: 10.1091/mbc.E09-06-0501. Epub 2009 Dec 2.

14.

The ghost in the machine: small GTPases as spatial regulators of exocytosis.

Wu H, Rossi G, Brennwald P.

Trends Cell Biol. 2008 Sep;18(9):397-404. doi: 10.1016/j.tcb.2008.06.007. Epub 2008 Aug 14. Review.

15.

Spatial regulation of exocytosis and cell polarity: yeast as a model for animal cells.

Brennwald P, Rossi G.

FEBS Lett. 2007 May 22;581(11):2119-24. Epub 2007 Mar 30. Review.

16.

Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism.

Hattendorf DA, Andreeva A, Gangar A, Brennwald PJ, Weis WI.

Nature. 2007 Mar 29;446(7135):567-71.

PMID:
17392788
17.

The yeast tumor suppressor homologue Sro7p is required for targeting of the sodium pumping ATPase to the cell surface.

Wadskog I, Forsmark A, Rossi G, Konopka C, Oyen M, Goksör M, Ronne H, Brennwald P, Adler L.

Mol Biol Cell. 2006 Dec;17(12):4988-5003. Epub 2006 Sep 27.

18.

Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domains.

Kallay LM, McNickle A, Brennwald PJ, Hubbard AL, Braiterman LT.

J Cell Biochem. 2006 Oct 1;99(2):647-64.

PMID:
16791850
19.

The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p.

Grosshans BL, Andreeva A, Gangar A, Niessen S, Yates JR 3rd, Brennwald P, Novick P.

J Cell Biol. 2006 Jan 2;172(1):55-66.

20.

Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast.

Routt SM, Ryan MM, Tyeryar K, Rizzieri KE, Mousley C, Roumanie O, Brennwald PJ, Bankaitis VA.

Traffic. 2005 Dec;6(12):1157-72.

21.

Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex.

Roumanie O, Wu H, Molk JN, Rossi G, Bloom K, Brennwald P.

J Cell Biol. 2005 Aug 15;170(4):583-94.

22.

Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis.

Zhang X, Wang P, Gangar A, Zhang J, Brennwald P, TerBush D, Guo W.

J Cell Biol. 2005 Jul 18;170(2):273-83.

23.

Structurally conserved interaction of Lgl family with SNAREs is critical to their cellular function.

Gangar A, Rossi G, Andreeva A, Hales R, Brennwald P.

Curr Biol. 2005 Jun 21;15(12):1136-42.

24.
25.

The yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machinery.

Elbert M, Rossi G, Brennwald P.

Mol Biol Cell. 2005 Feb;16(2):532-49. Epub 2004 Nov 24.

26.

Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton.

Cohen D, Brennwald PJ, Rodriguez-Boulan E, Müsch A.

J Cell Biol. 2004 Mar 1;164(5):717-27. Epub 2004 Feb 23.

27.

Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells.

Müsch A, Cohen D, Yeaman C, Nelson WJ, Rodriguez-Boulan E, Brennwald PJ.

Mol Biol Cell. 2002 Jan;13(1):158-68.

28.

Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud.

Adamo JE, Moskow JJ, Gladfelter AS, Viterbo D, Lew DJ, Brennwald PJ.

J Cell Biol. 2001 Nov 12;155(4):581-92. Epub 2001 Nov 12.

29.

A protein interaction map for cell polarity development.

Drees BL, Sundin B, Brazeau E, Caviston JP, Chen GC, Guo W, Kozminski KG, Lau MW, Moskow JJ, Tong A, Schenkman LR, McKenzie A 3rd, Brennwald P, Longtine M, Bi E, Chan C, Novick P, Boone C, Pringle JR, Davis TN, Fields S, Drubin DG.

J Cell Biol. 2001 Aug 6;154(3):549-71.

31.
32.

Reversal of fortune. Do Rab GTPases act on the target membrane?

Brennwald P.

J Cell Biol. 2000 Apr 3;149(1):1-4. No abstract available.

33.
34.
36.

Formation of a yeast SNARE complex is accompanied by significant structural changes.

Rice LM, Brennwald P, Brünger AT.

FEBS Lett. 1997 Sep 22;415(1):49-55.

37.

Interactions of nucleotide release factor Dss4p with Sec4p in the post-Golgi secretory pathway of yeast.

Collins RN, Brennwald P, Garrett M, Lauring A, Novick P.

J Biol Chem. 1997 Jul 18;272(29):18281-9.

38.
39.

Control of exocytosis in yeast.

Novick P, Garrett MD, Brennwald P, Lauring A, Finger FP, Collins R, TerBush DR.

Cold Spring Harb Symp Quant Biol. 1995;60:171-7. Review. No abstract available.

PMID:
8824389
40.

Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis.

Brennwald P, Kearns B, Champion K, Keränen S, Bankaitis V, Novick P.

Cell. 1994 Oct 21;79(2):245-58.

PMID:
7954793
41.

Genetic and biochemical analysis of the fission yeast ribonucleoprotein particle containing a homolog of Srp54p.

Selinger D, Brennwald P, Althoff S, Reich C, Hann B, Walter P, Wise JA.

Nucleic Acids Res. 1994 Jul 11;22(13):2557-67.

43.

Friends and family: the role of the Rab GTPases in vesicular traffic.

Novick P, Brennwald P.

Cell. 1993 Nov 19;75(4):597-601. Review. No abstract available.

PMID:
8242735
44.
46.

The cycle of SEC4 function in vesicular transport.

Novick P, Brennwald P, Walworth NC, Kabcenell AK, Garrett M, Moya M, Roberts D, Müller H, Govindan B, Bowser R.

Ciba Found Symp. 1993;176:218-28; discussion 229-32. Review.

PMID:
8299422
47.

Distinct and specific GAP activities in rat pancreas act on the yeast GTP-binding proteins Ypt1 and Sec4.

Jena BP, Brennwald P, Garrett MD, Novick P, Jamieson JD.

FEBS Lett. 1992 Aug 31;309(1):5-9.

48.
49.

The two similarly expressed genes encoding U3 snRNA in Schizosaccharomyces pombe lack introns.

Selinger DA, Porter GL, Brennwald PJ, Wise JA.

Mol Biol Evol. 1992 Mar;9(2):297-308.

PMID:
1560765
50.

Purification of Sec4 protein from Saccharomyces cerevisiae and Escherichia coli.

Novick P, Garrett MD, Brennwald P, Kabcenell AK.

Methods Enzymol. 1992;219:352-62. No abstract available.

PMID:
1488008

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