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Items: 1 to 50 of 79

1.

Overexpression of Sal-like protein 4 in head and neck cancer: epigenetic effects and clinical correlations.

Misawa K, Misawa Y, Mima M, Yamada S, Imai A, Mochizuki D, Nakagawa T, Kurokawa T, Endo S, Kawasaki H, Brenner JC, Mineta H.

Cell Oncol (Dordr). 2020 Apr 2. doi: 10.1007/s13402-020-00509-5. [Epub ahead of print]

PMID:
32240499
2.

Predictors of survival in patients undergoing oropharyngeal surgery for cancer recurrence after radiation therapy.

Heft Neal ME, Brennan J, Haring CT, Brenner JC, Worden F, Swiecicki P, Mierzwa M, Casper KA, Malloy KM, Stucken CL, McLean SA, Prince ME, Bradford CR, Wolf GT, Shuman AG, Chinn SB, Chepeha DB, Rosko AJ, Spector ME.

Eur Arch Otorhinolaryngol. 2020 Mar 19. doi: 10.1007/s00405-020-05913-z. [Epub ahead of print]

PMID:
32193723
3.

"My Research Is Their Business, but I'm Not Their Business": Patient and Clinician Perspectives on Commercialization of Precision Oncology Data.

Spector-Bagdady K, Krenz CD, Brummel C, Brenner JC, Bradford CR, Shuman AG.

Oncologist. 2020 Mar 13. doi: 10.1634/theoncologist.2019-0863. [Epub ahead of print]

4.

Rationale for the advancement of PI3K pathway inhibitors for personalized chordoma therapy.

Michmerhuizen NL, Owen JH, Heft Neal ME, Mann JE, Leonard E, Wang J, Zhai J, Jiang H, McHugh JB, Brenner JC, Prince MEP.

J Neurooncol. 2020 Mar;147(1):25-35. doi: 10.1007/s11060-020-03418-7. Epub 2020 Feb 17.

PMID:
32067197
5.

Speech and swallowing outcomes after laryngectomy for the dysfunctional irradiated larynx.

Farlow JL, Birkeland AC, Hardenbergh A, Lyden T, Brenner JC, Shuman AG, Chinn SB, Stucken CL, Malloy KM, Moyer JS, Casper KA, Prince MEP, Bradford CR, Wolf GT, Chepeha DB, Rosko AJ, Spector ME.

Eur Arch Otorhinolaryngol. 2020 Jan 27. doi: 10.1007/s00405-020-05809-y. [Epub ahead of print]

PMID:
31989269
6.

A multi-center phase II trial evaluating the efficacy of palbociclib in combination with carboplatin for the treatment of unresectable recurrent or metastatic head and neck squamous cell carcinoma.

Swiecicki PL, Durm G, Bellile E, Bhangale A, Brenner JC, Worden FP.

Invest New Drugs. 2020 Jan 24. doi: 10.1007/s10637-020-00898-2. [Epub ahead of print]

PMID:
31981071
7.

HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING.

Luo X, Donnelly CR, Gong W, Heath BR, Hao Y, Donnelly LA, Moghbeli T, Tan YS, Lin X, Bellile E, Kansy BA, Carey TE, Brenner JC, Cheng L, Polverini PJ, Morgan MA, Wen H, Prince ME, Ferris RL, Xie Y, Young S, Wolf GT, Chen Q, Lei YL.

J Clin Invest. 2020 Apr 1;130(4):1635-1652. doi: 10.1172/JCI129497.

8.

Patient and Provider Perspectives Regarding Enrollment in Head and Neck Cancer Research.

Shuman AG, Gornick MC, Brummel C, Kent M, Spector-Bagdady K, Biddle E, Bradford CR, Brenner JC.

Otolaryngol Head Neck Surg. 2020 Jan;162(1):73-78. doi: 10.1177/0194599819889976. Epub 2019 Dec 10.

PMID:
31818193
9.

Protecting Tumors by Preventing Human Papilloma Virus Antigen Presentation: Insights from Emerging Bioinformatics Algorithms.

Gensterblum-Miller E, Brenner JC.

Cancers (Basel). 2019 Oct 12;11(10). pii: E1543. doi: 10.3390/cancers11101543. Review.

10.

Predictors and Prevalence of Nodal Disease in Salvage Oropharyngectomy.

Heft Neal ME, Brennan J, Brenner JC, Shuman AG, Chinn SB, Stucken CL, Malloy KM, Moyer JS, Casper KA, McLean SA, Prince MEP, Bradford CR, Wolf GT, Chepeha DB, Rosko AJ, Spector ME.

Ann Surg Oncol. 2020 Feb;27(2):451-457. doi: 10.1245/s10434-019-07841-7. Epub 2019 Sep 19.

11.

Prognostic Value of Tumor-Infiltrating Lymphocytes in Head and Neck Squamous Cell Carcinoma.

Spector ME, Bellile E, Amlani L, Zarins K, Smith J, Brenner JC, Rozek L, Nguyen A, Thomas D, McHugh JB, Taylor JMG, Wolf GT; University of Michigan Head and Neck SPORE Program.

JAMA Otolaryngol Head Neck Surg. 2019 Sep 5. doi: 10.1001/jamaoto.2019.2427. [Epub ahead of print]

PMID:
31486841
12.

Head and Neck Cancer Immunotherapy beyond the Checkpoint Blockade.

Heath BR, Michmerhuizen NL, Donnelly CR, Sansanaphongpricha K, Sun D, Brenner JC, Lei YL.

J Dent Res. 2019 Sep;98(10):1073-1080. doi: 10.1177/0022034519864112. Epub 2019 Jul 24.

PMID:
31340724
13.

Window of opportunity trials in head and neck cancer.

Farlow JL, Birkeland AC, Swiecicki PL, Brenner JC, Spector ME.

J Cancer Metastasis Treat. 2019;5. pii: 18. doi: 10.20517/2394-4722.2018.100. Epub 2019 Mar 18.

14.

The molecular landscape of the University of Michigan laryngeal squamous cell carcinoma cell line panel.

Mann JE, Kulkarni A, Birkeland AC, Kafelghazal J, Eisenberg J, Jewell BM, Ludwig ML, Spector ME, Jiang H, Carey TE, Brenner JC.

Head Neck. 2019 Sep;41(9):3114-3124. doi: 10.1002/hed.25803. Epub 2019 May 15.

PMID:
31090975
15.

Rationale for Using Irreversible Epidermal Growth Factor Receptor Inhibitors in Combination with Phosphatidylinositol 3-Kinase Inhibitors for Advanced Head and Neck Squamous Cell Carcinoma.

Michmerhuizen NL, Leonard E, Matovina C, Harris M, Herbst G, Kulkarni A, Zhai J, Jiang H, Carey TE, Brenner JC.

Mol Pharmacol. 2019 May;95(5):528-536. doi: 10.1124/mol.118.115162. Epub 2019 Mar 11.

PMID:
30858165
16.

Elective Paratracheal Lymph Node Dissection in Salvage Laryngectomy.

Farlow JL, Birkeland AC, Rosko AJ, VanKoevering K, Haring CT, Smith JD, Brenner JC, Shuman AG, Chinn SB, Stucken CL, Malloy KM, Moyer JS, Casper KA, McLean SA, Prince MEP, Bradford CR, Wolf GT, Chepeha DB, Spector ME.

Ann Surg Oncol. 2019 Aug;26(8):2542-2548. doi: 10.1245/s10434-019-07270-6. Epub 2019 Mar 4.

PMID:
30830535
17.

Clinical characteristics, HIV status, and molecular biomarkers in squamous cell carcinoma of the conjunctiva in Ghana.

Merz LE, Afriyie O, Jiagge E, Adjei E, Foltin SK, Ludwig ML, McHugh JB, Brenner JC, Merajver SD.

Health Sci Rep. 2019 Jan 10;2(2):e108. doi: 10.1002/hsr2.108. eCollection 2019 Feb.

18.

Biospecimens, Research Consent, and Distinguishing Cell Line Research.

Spector-Bagdady K, Fernandez Lynch H, Brenner JC, Shuman AG.

JAMA Oncol. 2019 Mar 1;5(3):406-410. doi: 10.1001/jamaoncol.2018.6988.

19.

Head and Neck Squamous Cell Carcinoma Detection and Surveillance: Advances of Liquid Biomarkers.

Swiecicki PL, Brennan JR, Mierzwa M, Spector ME, Brenner JC.

Laryngoscope. 2019 Aug;129(8):1836-1843. doi: 10.1002/lary.27725. Epub 2018 Dec 20. Review.

PMID:
30570748
20.

Correction: Expression of immunohistochemical markers in non-oropharyngeal head and neck squamous cell carcinoma in Ghana.

Owusu-Afriyie O, Owiredu WKBA, Owusu-Danquah K, Komarck C, Foltin SK, Larsen-Reindorf R, Acheampong E, Quayson SE, Prince ME, McHugh JB, Donkor P, Merajver SD, Brenner JC.

PLoS One. 2018 Dec 19;13(12):e0209696. doi: 10.1371/journal.pone.0209696. eCollection 2018.

21.

Mutational profiles of persistent/recurrent laryngeal squamous cell carcinoma.

Smith JD, Birkeland AC, Rosko AJ, Hoesli RC, Foltin SK, Swiecicki P, Mierzwa M, Chinn SB, Shuman AG, Malloy KM, Casper KA, McLean SA, Wolf GT, Bradford CR, Prince ME, Brenner JC, Spector ME.

Head Neck. 2019 Feb;41(2):423-428. doi: 10.1002/hed.25444. Epub 2018 Dec 12.

22.

The genomic landscape of UM-SCC oral cavity squamous cell carcinoma cell lines.

Ludwig ML, Kulkarni A, Birkeland AC, Michmerhuizen NL, Foltin SK, Mann JE, Hoesli RC, Devenport SN, Jewell BM, Shuman AG, Spector ME, Carey TE, Jiang H, Brenner JC.

Oral Oncol. 2018 Dec;87:144-151. doi: 10.1016/j.oraloncology.2018.10.031. Epub 2018 Nov 8.

23.

Ablation of Cancer Stem Cells by Therapeutic Inhibition of the MDM2-p53 Interaction in Mucoepidermoid Carcinoma.

Andrews A, Warner K, Rodriguez-Ramirez C, Pearson AT, Nör F, Zhang Z, Kerk S, Kulkarni A, Helman JI, Brenner JC, Wicha MS, Wang S, Nör JE.

Clin Cancer Res. 2019 Mar 1;25(5):1588-1600. doi: 10.1158/1078-0432.CCR-17-2730. Epub 2018 Nov 29.

24.

Analysis of tumor-infiltrating CD103 resident memory T-cell content in recurrent laryngeal squamous cell carcinoma.

Mann JE, Smith JD, Birkeland AC, Bellile E, Swiecicki P, Mierzwa M, Chinn SB, Shuman AG, Malloy KM, Casper KA, McLean SA, Moyer JS, Wolf GT, Bradford CR, Prince ME, Carey TE, McHugh JB, Spector ME, Brenner JC.

Cancer Immunol Immunother. 2019 Feb;68(2):213-220. doi: 10.1007/s00262-018-2256-3. Epub 2018 Oct 25.

25.

Expression of immunohistochemical markers in non-oropharyngeal head and neck squamous cell carcinoma in Ghana.

Owusu-Afriyie O, Owiredu WKBA, Owusu-Danquah K, Komarck C, Foltin SK, Larsen-Reindorf R, Acheampong E, Quayson SE, Prince MEP, McHugh JB, Donkor P, Merajver SD, Brenner JC.

PLoS One. 2018 Aug 23;13(8):e0202790. doi: 10.1371/journal.pone.0202790. eCollection 2018. Erratum in: PLoS One. 2018 Dec 19;13(12):e0209696.

26.

The potential for liquid biopsies in head and neck cancer.

Spector ME, Farlow JL, Haring CT, Brenner JC, Birkeland AC.

Discov Med. 2018 May;25(139):251-257. Review.

27.

Whole-Exome Sequencing of Sinonasal Small Cell Carcinoma Arising within a Papillary Schneiderian Carcinoma In Situ.

Smith J, Kulkarni A, Birkeland AC, McHugh JB, Brenner JC.

Otolaryngol Head Neck Surg. 2018 Nov;159(5):859-865. doi: 10.1177/0194599818774004. Epub 2018 May 8.

28.

Proportion of CD4 and CD8 tumor infiltrating lymphocytes predicts survival in persistent/recurrent laryngeal squamous cell carcinoma.

Hoesli R, Birkeland AC, Rosko AJ, Issa M, Chow KL, Michmerhuizen NL, Mann JE, Chinn SB, Shuman AG, Prince ME, Wolf GT, Bradford CR, McHugh JB, Brenner JC, Spector ME.

Oral Oncol. 2018 Feb;77:83-89. doi: 10.1016/j.oraloncology.2017.12.003. Epub 2017 Dec 23.

29.

Specialty Group Medical Visits for Patients With Diabetes.

Ganetsky VS, Brenner JC, Kaufman ST.

Clin Diabetes. 2017 Dec;35(5):345-349. doi: 10.2337/cd15-0062. No abstract available.

30.

Predictors of survival after total laryngectomy for recurrent/persistent laryngeal squamous cell carcinoma.

Birkeland AC, Beesley L, Bellile E, Rosko AJ, Hoesli R, Chinn SB, Shuman AG, Prince ME, Wolf GT, Bradford CR, Brenner JC, Spector ME.

Head Neck. 2017 Dec;39(12):2512-2518. doi: 10.1002/hed.24918. Epub 2017 Sep 30.

31.

An Algorithm to Evaluate Suspected Lung Metastases in Patients with HPV-Associated Oropharyngeal Cancer.

VanKoevering KK, Marchiano E, Walline HM, Carey TE, McHugh JB, Brenner JC, Goudsmit CM, Belille E, Spector ME, Shuman AG; University of Michigan Head and Neck SPORE Team.

Otolaryngol Head Neck Surg. 2018 Jan;158(1):118-121. doi: 10.1177/0194599817733677. Epub 2017 Sep 26.

32.

Pathogenetic Analysis of Sinonasal Teratocarcinosarcomas Reveal Actionable β-catenin Overexpression and a β-catenin Mutation.

Birkeland AC, Burgin SJ, Yanik M, Scott MV, Bradford CR, McHugh JB, McLean SA, Sullivan SE, Nor JE, McKean EL, Brenner JC.

J Neurol Surg B Skull Base. 2017 Aug;78(4):346-352. doi: 10.1055/s-0037-1601320. Epub 2017 Mar 27.

33.

Preoperative Tracheostomy Is Associated with Poor Disease-Free Survival in Recurrent Laryngeal Cancer.

Birkeland AC, Rosko AJ, Beesley L, Bellile E, Chinn SB, Shuman AG, Prince ME, Wolf GT, Bradford CR, Brenner JC, Spector ME.

Otolaryngol Head Neck Surg. 2017 Sep;157(3):432-438. doi: 10.1177/0194599817709236. Epub 2017 Jun 6.

34.

Correlation of Crtc1/3-Maml2 fusion status, grade and survival in mucoepidermoid carcinoma.

Birkeland AC, Foltin SK, Michmerhuizen NL, Hoesli RC, Rosko AJ, Byrd S, Yanik M, Nor JE, Bradford CR, Prince ME, Carey TE, McHugh JB, Spector ME, Brenner JC.

Oral Oncol. 2017 May;68:5-8. doi: 10.1016/j.oraloncology.2017.02.025. Epub 2017 Mar 10.

35.

Immortal Life of the Common Rule: Ethics, Consent, and the Future of Cancer Research.

Smith JD, Birkeland AC, Goldman EB, Brenner JC, Carey TE, Spector-Bagdady K, Shuman AG.

J Clin Oncol. 2017 Jun 10;35(17):1879-1883. doi: 10.1200/JCO.2016.68.4522. Epub 2017 Apr 20. No abstract available. Erratum in: J Clin Oncol. 2017 Dec 20;35(36):4096.

36.

Surveilling the Potential for Precision Medicine-driven PD-1/PD-L1-targeted Therapy in HNSCC.

Mann JE, Hoesli R, Michmerhuizen NL, Devenport SN, Ludwig ML, Vandenberg TR, Matovina C, Jawad N, Mierzwa M, Shuman AG, Spector ME, Brenner JC.

J Cancer. 2017 Feb 9;8(3):332-344. doi: 10.7150/jca.17547. eCollection 2017. Review.

37.

Genomic sequencing and precision medicine in head and neck cancers.

Hoesli RC, Ludwig ML, Michmerhuizen NL, Rosko AJ, Spector ME, Brenner JC, Birkeland AC.

Eur J Surg Oncol. 2017 May;43(5):884-892. doi: 10.1016/j.ejso.2016.12.002. Epub 2016 Dec 15. Review.

38.

Differential compensation mechanisms define resistance to PI3K inhibitors in PIK3CA amplified HNSCC.

Michmerhuizen NL, Leonard E, Kulkarni A, Brenner JC.

Otorhinolaryngol Head Neck Surg. 2016;1(2):44-50. Epub 2016 Jun 7.

39.

Genetic determinants in head and neck squamous cell carcinoma and their influence on global personalized medicine.

Michmerhuizen NL, Birkeland AC, Bradford CR, Brenner JC.

Genes Cancer. 2016 May;7(5-6):182-200. doi: 10.18632/genesandcancer.110.

40.

Genomic Integration of High-Risk HPV Alters Gene Expression in Oropharyngeal Squamous Cell Carcinoma.

Walline HM, Komarck CM, McHugh JB, Bellile EL, Brenner JC, Prince ME, McKean EL, Chepeha DB, Wolf GT, Worden FP, Bradford CR, Carey TE.

Mol Cancer Res. 2016 Oct;14(10):941-952. Epub 2016 Jul 15.

41.

Changing the paradigm: the potential for targeted therapy in laryngeal squamous cell carcinoma.

Ludwig ML, Birkeland AC, Hoesli R, Swiecicki P, Spector ME, Brenner JC.

Cancer Biol Med. 2016 Mar;13(1):87-100. doi: 10.28092/j.issn.2095-3941.2016.0010.

42.

In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model.

Rudy SF, Brenner JC, Harris JL, Liu J, Che J, Scott MV, Owen JH, Komarck CM, Graham MP, Bellile EL, Bradford CR, Prince ME, Carey TE.

J Otolaryngol Head Neck Surg. 2016 Apr 26;45:26. doi: 10.1186/s40463-016-0140-8.

43.

Identification of Targetable ERBB2 Aberrations in Head and Neck Squamous Cell Carcinoma.

Birkeland AC, Yanik M, Tillman BN, Scott MV, Foltin SK, Mann JE, Michmerhuizen NL, Ludwig ML, Sandelski MM, Komarck CM, Carey TE, Prince ME, Bradford CR, McHugh JB, Spector ME, Brenner JC.

JAMA Otolaryngol Head Neck Surg. 2016 Jun 1;142(6):559-67. doi: 10.1001/jamaoto.2016.0335.

44.
45.

The potential for tumor suppressor gene therapy in head and neck cancer.

Birkeland AC, Ludwig ML, Spector ME, Brenner JC.

Discov Med. 2016 Jan;21(113):41-7. Review.

46.

Occult Nodal Disease Prevalence and Distribution in Recurrent Laryngeal Cancer Requiring Salvage Laryngectomy.

Birkeland AC, Rosko AJ, Issa MR, Shuman AG, Prince ME, Wolf GT, Bradford CR, McHugh JB, Brenner JC, Spector ME.

Otolaryngol Head Neck Surg. 2016 Mar;154(3):473-9. doi: 10.1177/0194599815627811. Epub 2016 Feb 16.

47.

Moving towards personalised therapy in head and neck squamous cell carcinoma through analysis of next generation sequencing data.

Giefing M, Wierzbicka M, Szyfter K, Brenner JC, Braakhuis BJ, Brakenhoff RH, Bradford CR, Sorensen JA, Rinaldo A, Rodrigo JP, Takes RP, Ferlito A.

Eur J Cancer. 2016 Mar;55:147-57. doi: 10.1016/j.ejca.2015.10.070. Epub 2016 Feb 4. Review.

48.

Fibroblast growth factor family aberrations as a putative driver of head and neck squamous cell carcinoma in an epidemiologically low-risk patient as defined by targeted sequencing.

Tillman BN, Yanik M, Birkeland AC, Liu CJ, Hovelson DH, Cani AK, Palanisamy N, Carskadon S, Carey TE, Bradford CR, Tomlins SA, McHugh JB, Spector ME, Brenner JCh.

Head Neck. 2016 Apr;38 Suppl 1:E1646-52. doi: 10.1002/hed.24292. Epub 2016 Feb 5.

49.

A review of drugs in development for the personalized treatment of head and neck squamous cell carcinoma.

Birkeland AC, Swiecicki PL, Brenner JC, Shuman AG.

Expert Rev Precis Med Drug Dev. 2016;1(4):379-385. doi: 10.1080/23808993.2016.1208050. Epub 2016 Jul 15.

50.

The Tip of the Iceberg: Clinical Implications of Genomic Sequencing Projects in Head and Neck Cancer.

Birkeland AC, Ludwig ML, Meraj TS, Brenner JC, Prince ME.

Cancers (Basel). 2015 Oct 21;7(4):2094-109. doi: 10.3390/cancers7040879. Review.

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