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Items: 1 to 50 of 71

1.

Protecting Tumors by Preventing Human Papilloma Virus Antigen Presentation: Insights from Emerging Bioinformatics Algorithms.

Gensterblum-Miller E, Brenner JC.

Cancers (Basel). 2019 Oct 12;11(10). pii: E1543. doi: 10.3390/cancers11101543. Review.

2.

Predictors and Prevalence of Nodal Disease in Salvage Oropharyngectomy.

Heft Neal ME, Brennan J, Brenner JC, Shuman AG, Chinn SB, Stucken CL, Malloy KM, Moyer JS, Casper KA, McLean SA, Prince MEP, Bradford CR, Wolf GT, Chepeha DB, Rosko AJ, Spector ME.

Ann Surg Oncol. 2019 Sep 19. doi: 10.1245/s10434-019-07841-7. [Epub ahead of print]

PMID:
31538289
3.

Prognostic Value of Tumor-Infiltrating Lymphocytes in Head and Neck Squamous Cell Carcinoma.

Spector ME, Bellile E, Amlani L, Zarins K, Smith J, Brenner JC, Rozek L, Nguyen A, Thomas D, McHugh JB, Taylor JMG, Wolf GT; University of Michigan Head and Neck SPORE Program.

JAMA Otolaryngol Head Neck Surg. 2019 Sep 5. doi: 10.1001/jamaoto.2019.2427. [Epub ahead of print]

PMID:
31486841
4.

Head and Neck Cancer Immunotherapy beyond the Checkpoint Blockade.

Heath BR, Michmerhuizen NL, Donnelly CR, Sansanaphongpricha K, Sun D, Brenner JC, Lei YL.

J Dent Res. 2019 Sep;98(10):1073-1080. doi: 10.1177/0022034519864112. Epub 2019 Jul 24.

PMID:
31340724
5.

Window of opportunity trials in head and neck cancer.

Farlow JL, Birkeland AC, Swiecicki PL, Brenner JC, Spector ME.

J Cancer Metastasis Treat. 2019;5. pii: 18. doi: 10.20517/2394-4722.2018.100. Epub 2019 Mar 18.

6.

The molecular landscape of the University of Michigan laryngeal squamous cell carcinoma cell line panel.

Mann JE, Kulkarni A, Birkeland AC, Kafelghazal J, Eisenberg J, Jewell BM, Ludwig ML, Spector ME, Jiang H, Carey TE, Brenner JC.

Head Neck. 2019 Sep;41(9):3114-3124. doi: 10.1002/hed.25803. Epub 2019 May 15.

PMID:
31090975
7.

Rationale for Using Irreversible Epidermal Growth Factor Receptor Inhibitors in Combination with Phosphatidylinositol 3-Kinase Inhibitors for Advanced Head and Neck Squamous Cell Carcinoma.

Michmerhuizen NL, Leonard E, Matovina C, Harris M, Herbst G, Kulkarni A, Zhai J, Jiang H, Carey TE, Brenner JC.

Mol Pharmacol. 2019 May;95(5):528-536. doi: 10.1124/mol.118.115162. Epub 2019 Mar 11.

PMID:
30858165
8.

Elective Paratracheal Lymph Node Dissection in Salvage Laryngectomy.

Farlow JL, Birkeland AC, Rosko AJ, VanKoevering K, Haring CT, Smith JD, Brenner JC, Shuman AG, Chinn SB, Stucken CL, Malloy KM, Moyer JS, Casper KA, McLean SA, Prince MEP, Bradford CR, Wolf GT, Chepeha DB, Spector ME.

Ann Surg Oncol. 2019 Aug;26(8):2542-2548. doi: 10.1245/s10434-019-07270-6. Epub 2019 Mar 4.

PMID:
30830535
9.

Clinical characteristics, HIV status, and molecular biomarkers in squamous cell carcinoma of the conjunctiva in Ghana.

Merz LE, Afriyie O, Jiagge E, Adjei E, Foltin SK, Ludwig ML, McHugh JB, Brenner JC, Merajver SD.

Health Sci Rep. 2019 Jan 10;2(2):e108. doi: 10.1002/hsr2.108. eCollection 2019 Feb.

10.

Biospecimens, Research Consent, and Distinguishing Cell Line Research.

Spector-Bagdady K, Fernandez Lynch H, Brenner JC, Shuman AG.

JAMA Oncol. 2019 Mar 1;5(3):406-410. doi: 10.1001/jamaoncol.2018.6988.

PMID:
30703213
11.

Head and Neck Squamous Cell Carcinoma Detection and Surveillance: Advances of Liquid Biomarkers.

Swiecicki PL, Brennan JR, Mierzwa M, Spector ME, Brenner JC.

Laryngoscope. 2019 Aug;129(8):1836-1843. doi: 10.1002/lary.27725. Epub 2018 Dec 20. Review.

PMID:
30570748
12.

Correction: Expression of immunohistochemical markers in non-oropharyngeal head and neck squamous cell carcinoma in Ghana.

Owusu-Afriyie O, Owiredu WKBA, Owusu-Danquah K, Komarck C, Foltin SK, Larsen-Reindorf R, Acheampong E, Quayson SE, Prince ME, McHugh JB, Donkor P, Merajver SD, Brenner JC.

PLoS One. 2018 Dec 19;13(12):e0209696. doi: 10.1371/journal.pone.0209696. eCollection 2018.

13.

Mutational profiles of persistent/recurrent laryngeal squamous cell carcinoma.

Smith JD, Birkeland AC, Rosko AJ, Hoesli RC, Foltin SK, Swiecicki P, Mierzwa M, Chinn SB, Shuman AG, Malloy KM, Casper KA, McLean SA, Wolf GT, Bradford CR, Prince ME, Brenner JC, Spector ME.

Head Neck. 2019 Feb;41(2):423-428. doi: 10.1002/hed.25444. Epub 2018 Dec 12.

PMID:
30548484
14.

The genomic landscape of UM-SCC oral cavity squamous cell carcinoma cell lines.

Ludwig ML, Kulkarni A, Birkeland AC, Michmerhuizen NL, Foltin SK, Mann JE, Hoesli RC, Devenport SN, Jewell BM, Shuman AG, Spector ME, Carey TE, Jiang H, Brenner JC.

Oral Oncol. 2018 Dec;87:144-151. doi: 10.1016/j.oraloncology.2018.10.031. Epub 2018 Nov 8.

PMID:
30527230
15.

Ablation of Cancer Stem Cells by Therapeutic Inhibition of the MDM2-p53 Interaction in Mucoepidermoid Carcinoma.

Andrews A, Warner K, Rodriguez-Ramirez C, Pearson AT, Nör F, Zhang Z, Kerk S, Kulkarni A, Helman JI, Brenner JC, Wicha MS, Wang S, Nör JE.

Clin Cancer Res. 2019 Mar 1;25(5):1588-1600. doi: 10.1158/1078-0432.CCR-17-2730. Epub 2018 Nov 29.

PMID:
30498096
16.

Analysis of tumor-infiltrating CD103 resident memory T-cell content in recurrent laryngeal squamous cell carcinoma.

Mann JE, Smith JD, Birkeland AC, Bellile E, Swiecicki P, Mierzwa M, Chinn SB, Shuman AG, Malloy KM, Casper KA, McLean SA, Moyer JS, Wolf GT, Bradford CR, Prince ME, Carey TE, McHugh JB, Spector ME, Brenner JC.

Cancer Immunol Immunother. 2019 Feb;68(2):213-220. doi: 10.1007/s00262-018-2256-3. Epub 2018 Oct 25.

PMID:
30361882
17.

Expression of immunohistochemical markers in non-oropharyngeal head and neck squamous cell carcinoma in Ghana.

Owusu-Afriyie O, Owiredu WKBA, Owusu-Danquah K, Komarck C, Foltin SK, Larsen-Reindorf R, Acheampong E, Quayson SE, Prince MEP, McHugh JB, Donkor P, Merajver SD, Brenner JC.

PLoS One. 2018 Aug 23;13(8):e0202790. doi: 10.1371/journal.pone.0202790. eCollection 2018. Erratum in: PLoS One. 2018 Dec 19;13(12):e0209696.

18.

The potential for liquid biopsies in head and neck cancer.

Spector ME, Farlow JL, Haring CT, Brenner JC, Birkeland AC.

Discov Med. 2018 May;25(139):251-257. Review.

19.

Whole-Exome Sequencing of Sinonasal Small Cell Carcinoma Arising within a Papillary Schneiderian Carcinoma In Situ.

Smith J, Kulkarni A, Birkeland AC, McHugh JB, Brenner JC.

Otolaryngol Head Neck Surg. 2018 Nov;159(5):859-865. doi: 10.1177/0194599818774004. Epub 2018 May 8.

20.

Proportion of CD4 and CD8 tumor infiltrating lymphocytes predicts survival in persistent/recurrent laryngeal squamous cell carcinoma.

Hoesli R, Birkeland AC, Rosko AJ, Issa M, Chow KL, Michmerhuizen NL, Mann JE, Chinn SB, Shuman AG, Prince ME, Wolf GT, Bradford CR, McHugh JB, Brenner JC, Spector ME.

Oral Oncol. 2018 Feb;77:83-89. doi: 10.1016/j.oraloncology.2017.12.003. Epub 2017 Dec 23.

21.

Specialty Group Medical Visits for Patients With Diabetes.

Ganetsky VS, Brenner JC, Kaufman ST.

Clin Diabetes. 2017 Dec;35(5):345-349. doi: 10.2337/cd15-0062. No abstract available.

22.

Predictors of survival after total laryngectomy for recurrent/persistent laryngeal squamous cell carcinoma.

Birkeland AC, Beesley L, Bellile E, Rosko AJ, Hoesli R, Chinn SB, Shuman AG, Prince ME, Wolf GT, Bradford CR, Brenner JC, Spector ME.

Head Neck. 2017 Dec;39(12):2512-2518. doi: 10.1002/hed.24918. Epub 2017 Sep 30.

23.

An Algorithm to Evaluate Suspected Lung Metastases in Patients with HPV-Associated Oropharyngeal Cancer.

VanKoevering KK, Marchiano E, Walline HM, Carey TE, McHugh JB, Brenner JC, Goudsmit CM, Belille E, Spector ME, Shuman AG; University of Michigan Head and Neck SPORE Team.

Otolaryngol Head Neck Surg. 2018 Jan;158(1):118-121. doi: 10.1177/0194599817733677. Epub 2017 Sep 26.

24.

Pathogenetic Analysis of Sinonasal Teratocarcinosarcomas Reveal Actionable β-catenin Overexpression and a β-catenin Mutation.

Birkeland AC, Burgin SJ, Yanik M, Scott MV, Bradford CR, McHugh JB, McLean SA, Sullivan SE, Nor JE, McKean EL, Brenner JC.

J Neurol Surg B Skull Base. 2017 Aug;78(4):346-352. doi: 10.1055/s-0037-1601320. Epub 2017 Mar 27.

25.

Preoperative Tracheostomy Is Associated with Poor Disease-Free Survival in Recurrent Laryngeal Cancer.

Birkeland AC, Rosko AJ, Beesley L, Bellile E, Chinn SB, Shuman AG, Prince ME, Wolf GT, Bradford CR, Brenner JC, Spector ME.

Otolaryngol Head Neck Surg. 2017 Sep;157(3):432-438. doi: 10.1177/0194599817709236. Epub 2017 Jun 6.

26.

Correlation of Crtc1/3-Maml2 fusion status, grade and survival in mucoepidermoid carcinoma.

Birkeland AC, Foltin SK, Michmerhuizen NL, Hoesli RC, Rosko AJ, Byrd S, Yanik M, Nor JE, Bradford CR, Prince ME, Carey TE, McHugh JB, Spector ME, Brenner JC.

Oral Oncol. 2017 May;68:5-8. doi: 10.1016/j.oraloncology.2017.02.025. Epub 2017 Mar 10.

27.

Immortal Life of the Common Rule: Ethics, Consent, and the Future of Cancer Research.

Smith JD, Birkeland AC, Goldman EB, Brenner JC, Carey TE, Spector-Bagdady K, Shuman AG.

J Clin Oncol. 2017 Jun 10;35(17):1879-1883. doi: 10.1200/JCO.2016.68.4522. Epub 2017 Apr 20. No abstract available. Erratum in: J Clin Oncol. 2017 Dec 20;35(36):4096.

28.

Surveilling the Potential for Precision Medicine-driven PD-1/PD-L1-targeted Therapy in HNSCC.

Mann JE, Hoesli R, Michmerhuizen NL, Devenport SN, Ludwig ML, Vandenberg TR, Matovina C, Jawad N, Mierzwa M, Shuman AG, Spector ME, Brenner JC.

J Cancer. 2017 Feb 9;8(3):332-344. doi: 10.7150/jca.17547. eCollection 2017. Review.

29.

Genomic sequencing and precision medicine in head and neck cancers.

Hoesli RC, Ludwig ML, Michmerhuizen NL, Rosko AJ, Spector ME, Brenner JC, Birkeland AC.

Eur J Surg Oncol. 2017 May;43(5):884-892. doi: 10.1016/j.ejso.2016.12.002. Epub 2016 Dec 15. Review.

30.

Differential compensation mechanisms define resistance to PI3K inhibitors in PIK3CA amplified HNSCC.

Michmerhuizen NL, Leonard E, Kulkarni A, Brenner JC.

Otorhinolaryngol Head Neck Surg. 2016;1(2):44-50. Epub 2016 Jun 7.

31.

Genetic determinants in head and neck squamous cell carcinoma and their influence on global personalized medicine.

Michmerhuizen NL, Birkeland AC, Bradford CR, Brenner JC.

Genes Cancer. 2016 May;7(5-6):182-200. doi: 10.18632/genesandcancer.110.

32.

Genomic Integration of High-Risk HPV Alters Gene Expression in Oropharyngeal Squamous Cell Carcinoma.

Walline HM, Komarck CM, McHugh JB, Bellile EL, Brenner JC, Prince ME, McKean EL, Chepeha DB, Wolf GT, Worden FP, Bradford CR, Carey TE.

Mol Cancer Res. 2016 Oct;14(10):941-952. Epub 2016 Jul 15.

33.

Changing the paradigm: the potential for targeted therapy in laryngeal squamous cell carcinoma.

Ludwig ML, Birkeland AC, Hoesli R, Swiecicki P, Spector ME, Brenner JC.

Cancer Biol Med. 2016 Mar;13(1):87-100. doi: 10.28092/j.issn.2095-3941.2016.0010.

34.

In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model.

Rudy SF, Brenner JC, Harris JL, Liu J, Che J, Scott MV, Owen JH, Komarck CM, Graham MP, Bellile EL, Bradford CR, Prince ME, Carey TE.

J Otolaryngol Head Neck Surg. 2016 Apr 26;45:26. doi: 10.1186/s40463-016-0140-8.

35.

Identification of Targetable ERBB2 Aberrations in Head and Neck Squamous Cell Carcinoma.

Birkeland AC, Yanik M, Tillman BN, Scott MV, Foltin SK, Mann JE, Michmerhuizen NL, Ludwig ML, Sandelski MM, Komarck CM, Carey TE, Prince ME, Bradford CR, McHugh JB, Spector ME, Brenner JC.

JAMA Otolaryngol Head Neck Surg. 2016 Jun 1;142(6):559-67. doi: 10.1001/jamaoto.2016.0335.

36.
37.

The potential for tumor suppressor gene therapy in head and neck cancer.

Birkeland AC, Ludwig ML, Spector ME, Brenner JC.

Discov Med. 2016 Jan;21(113):41-7. Review.

38.

Occult Nodal Disease Prevalence and Distribution in Recurrent Laryngeal Cancer Requiring Salvage Laryngectomy.

Birkeland AC, Rosko AJ, Issa MR, Shuman AG, Prince ME, Wolf GT, Bradford CR, McHugh JB, Brenner JC, Spector ME.

Otolaryngol Head Neck Surg. 2016 Mar;154(3):473-9. doi: 10.1177/0194599815627811. Epub 2016 Feb 16.

39.

Moving towards personalised therapy in head and neck squamous cell carcinoma through analysis of next generation sequencing data.

Giefing M, Wierzbicka M, Szyfter K, Brenner JC, Braakhuis BJ, Brakenhoff RH, Bradford CR, Sorensen JA, Rinaldo A, Rodrigo JP, Takes RP, Ferlito A.

Eur J Cancer. 2016 Mar;55:147-57. doi: 10.1016/j.ejca.2015.10.070. Epub 2016 Feb 4. Review.

40.

Fibroblast growth factor family aberrations as a putative driver of head and neck squamous cell carcinoma in an epidemiologically low-risk patient as defined by targeted sequencing.

Tillman BN, Yanik M, Birkeland AC, Liu CJ, Hovelson DH, Cani AK, Palanisamy N, Carskadon S, Carey TE, Bradford CR, Tomlins SA, McHugh JB, Spector ME, Brenner JCh.

Head Neck. 2016 Apr;38 Suppl 1:E1646-52. doi: 10.1002/hed.24292. Epub 2016 Feb 5.

41.

A review of drugs in development for the personalized treatment of head and neck squamous cell carcinoma.

Birkeland AC, Swiecicki PL, Brenner JC, Shuman AG.

Expert Rev Precis Med Drug Dev. 2016;1(4):379-385. doi: 10.1080/23808993.2016.1208050. Epub 2016 Jul 15.

42.

The Tip of the Iceberg: Clinical Implications of Genomic Sequencing Projects in Head and Neck Cancer.

Birkeland AC, Ludwig ML, Meraj TS, Brenner JC, Prince ME.

Cancers (Basel). 2015 Oct 21;7(4):2094-109. doi: 10.3390/cancers7040879. Review.

43.

A lean neck mass clinic model: Adding value to care.

Tillman BN, Glazer TA, Ray A, Brenner JC, Spector ME.

Laryngoscope. 2015 Nov;125(11):2509-13. doi: 10.1002/lary.25535. Epub 2015 Aug 8.

44.

Getting personal: Head and neck cancer management in the era of genomic medicine.

Birkeland AC, Uhlmann WR, Brenner JC, Shuman AG.

Head Neck. 2016 Apr;38 Suppl 1:E2250-8. doi: 10.1002/hed.24132. Epub 2015 Aug 13. Review.

45.

Tumor evolution and progression in multifocal and paired non-invasive/invasive urothelial carcinoma.

Warrick JI, Hovelson DH, Amin A, Liu CJ, Cani AK, McDaniel AS, Yadati V, Quist MJ, Weizer AZ, Brenner JC, Feng FY, Mehra R, Grasso CS, Tomlins SA.

Virchows Arch. 2015 Mar;466(3):297-311. doi: 10.1007/s00428-014-1699-y. Epub 2014 Dec 11.

46.

Molecular pathways: targeting ETS gene fusions in cancer.

Feng FY, Brenner JC, Hussain M, Chinnaiyan AM.

Clin Cancer Res. 2014 Sep 1;20(17):4442-8. doi: 10.1158/1078-0432.CCR-13-0275. Epub 2014 Jun 23. Review.

47.

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.

Liu J, Pan S, Hsieh MH, Ng N, Sun F, Wang T, Kasibhatla S, Schuller AG, Li AG, Cheng D, Li J, Tompkins C, Pferdekamper A, Steffy A, Cheng J, Kowal C, Phung V, Guo G, Wang Y, Graham MP, Flynn S, Brenner JC, Li C, Villarroel MC, Schultz PG, Wu X, McNamara P, Sellers WR, Petruzzelli L, Boral AL, Seidel HM, McLaughlin ME, Che J, Carey TE, Vanasse G, Harris JL.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20224-9. doi: 10.1073/pnas.1314239110. Epub 2013 Nov 25.

48.

Targeted radiosensitization of ETS fusion-positive prostate cancer through PARP1 inhibition.

Han S, Brenner JC, Sabolch A, Jackson W, Speers C, Wilder-Romans K, Knudsen KE, Lawrence TS, Chinnaiyan AM, Feng FY.

Neoplasia. 2013 Oct;15(10):1207-17.

49.

Generating hypotheses about care needs of high utilizers: lessons from patient interviews.

Mautner DB, Pang H, Brenner JC, Shea JA, Gross KS, Frasso R, Cannuscio CC.

Popul Health Manag. 2013;16 Suppl 1:S26-33. doi: 10.1089/pop.2013.0033.

PMID:
24070247
50.

Building a citywide, all-payer, hospital claims database to improve health care delivery in a low-income, urban community.

Gross K, Brenner JC, Truchil A, Post EM, Riley AH.

Popul Health Manag. 2013;16 Suppl 1:S20-5. doi: 10.1089/pop.2013.0037.

PMID:
24070246

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