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Items: 1 to 50 of 70

1.

In vitro selective cytotoxicity of the dietary chalcone cardamonin (CD) on melanoma compared to healthy cells is mediated by apoptosis.

Berning L, Scharf L, Aplak E, Stucki D, von Montfort C, Reichert AS, Stahl W, Brenneisen P.

PLoS One. 2019 Sep 25;14(9):e0222267. doi: 10.1371/journal.pone.0222267. eCollection 2019.

2.

Carbon monoxide releasing molecule 401 (CORM-401) modulates phase I metabolism of xenobiotics.

Walter M, Stahl W, Brenneisen P, Reichert AS, Stucki D.

Toxicol In Vitro. 2019 Sep;59:215-220. doi: 10.1016/j.tiv.2019.04.018. Epub 2019 Apr 17.

PMID:
31004742
3.

The BH3 mimetic compound BH3I-1 impairs mitochondrial dynamics and promotes stress response in addition to its pro-apoptotic key function.

Stucki D, Brenneisen P, Reichert AS, Stahl W.

Toxicol Lett. 2018 Oct 1;295:369-378. doi: 10.1016/j.toxlet.2018.07.017. Epub 2018 Jul 18.

PMID:
30031050
4.

Efficacy of Different Compositions of Cerium Oxide Nanoparticles in Tumor-Stroma Interaction.

Sack-Zschauer M, Karaman-Aplak E, Wyrich C, Das S, Schubert T, Meyer H, Janiak C, Seal S, Stahl W, Brenneisen P.

J Biomed Nanotechnol. 2017 Dec 1;13(12):1735-1746. doi: 10.1166/jbn.2017.2452.

PMID:
29490761
5.

Nanotherapy and Reactive Oxygen Species (ROS) in Cancer: A Novel Perspective.

Brenneisen P, Reichert AS.

Antioxidants (Basel). 2018 Feb 22;7(2). pii: E31. doi: 10.3390/antiox7020031.

6.

UVA-1 exposure in vivo leads to an IL-6 surge within the skin.

Schneider LA, Raizner K, Wlaschek M, Brenneisen P, Gethöffer K, Scharffetter-Kochanek K.

Exp Dermatol. 2017 Sep;26(9):830-832. doi: 10.1111/exd.13286. Epub 2017 Apr 11.

PMID:
28094867
7.

A three-dimensional skin equivalent reflecting some aspects of in vivo aged skin.

Diekmann J, Alili L, Scholz O, Giesen M, Holtkötter O, Brenneisen P.

Exp Dermatol. 2016 Jan;25(1):56-61. doi: 10.1111/exd.12866. Epub 2015 Nov 23.

PMID:
26440058
8.

Effect of Fe3O4 Nanoparticles on Skin Tumor Cells and Dermal Fibroblasts.

Alili L, Chapiro S, Marten GU, Schmidt AM, Zanger K, Brenneisen P.

Biomed Res Int. 2015;2015:530957. doi: 10.1155/2015/530957. Epub 2015 May 21.

9.

Redox-active cerium oxide nanoparticles protect human dermal fibroblasts from PQ-induced damage.

von Montfort C, Alili L, Teuber-Hanselmann S, Brenneisen P.

Redox Biol. 2015;4:1-5. doi: 10.1016/j.redox.2014.11.007. Epub 2014 Nov 22.

10.

A drug-induced accelerated senescence (DIAS) is a possibility to study aging in time lapse.

Alili L, Diekmann J, Giesen M, Holtkötter O, Brenneisen P.

Age (Dordr). 2014 Jun;36(3):9658. doi: 10.1007/s11357-014-9658-8. Epub 2014 May 16.

11.

Combination of conventional chemotherapeutics with redox-active cerium oxide nanoparticles--a novel aspect in cancer therapy.

Sack M, Alili L, Karaman E, Das S, Gupta A, Seal S, Brenneisen P.

Mol Cancer Ther. 2014 Jul;13(7):1740-9. doi: 10.1158/1535-7163.MCT-13-0950. Epub 2014 May 13.

12.

Fibroblast-to-myofibroblast switch is mediated by NAD(P)H oxidase generated reactive oxygen species.

Alili L, Sack M, Puschmann K, Brenneisen P.

Biosci Rep. 2014 Feb 1;34(1). pii: e00089. Print 2014 Feb 1.

13.

Downregulation of tumor growth and invasion by redox-active nanoparticles.

Alili L, Sack M, von Montfort C, Giri S, Das S, Carroll KS, Zanger K, Seal S, Brenneisen P.

Antioxid Redox Signal. 2013 Sep 10;19(8):765-78. doi: 10.1089/ars.2012.4831. Epub 2013 Jan 24.

14.

Combined cytotoxic and anti-invasive properties of redox-active nanoparticles in tumor-stroma interactions.

Alili L, Sack M, Karakoti AS, Teuber S, Puschmann K, Hirst SM, Reilly CM, Zanger K, Stahl W, Das S, Seal S, Brenneisen P.

Biomaterials. 2011 Apr;32(11):2918-29. doi: 10.1016/j.biomaterials.2010.12.056. Epub 2011 Jan 26.

PMID:
21269688
15.

Stromal resistance of fibroblasts against oxidative damage: involvement of tumor cell-secreted platelet-derived growth factor (PDGF) and phosphoinositide 3-kinase (PI3K) activation.

Werth C, Stuhlmann D, Cat B, Steinbrenner H, Alili L, Sies H, Brenneisen P.

Carcinogenesis. 2008 Feb;29(2):404-10. doi: 10.1093/carcin/bgm296. Epub 2008 Jan 3.

PMID:
18174235
16.

Post-translational processing of selenoprotein P: implications of glycosylation for its utilisation by target cells.

Steinbrenner H, Alili L, Stuhlmann D, Sies H, Brenneisen P.

Biol Chem. 2007 Oct;388(10):1043-51.

PMID:
17937618
17.

Tirilazad amelioriates extracellular effects of photooxidative stress by sealing the membrane of UVA irradiated human dermal fibroblasts.

Schneider LA, Dissemond J, Schwamborn E, Wlaschek M, Brenneisen P, Scharffetter-Kochanek K.

Eur J Dermatol. 2006 Sep-Oct;16(5):530-6.

PMID:
17101474
18.

Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity.

Steinbrenner H, Bilgic E, Alili L, Sies H, Brenneisen P.

Free Radic Res. 2006 Sep;40(9):936-43.

PMID:
17015273
19.

Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species.

Cat B, Stuhlmann D, Steinbrenner H, Alili L, Holtkötter O, Sies H, Brenneisen P.

J Cell Sci. 2006 Jul 1;119(Pt 13):2727-38. Epub 2006 Jun 6.

20.

Involvement of selenoprotein P in protection of human astrocytes from oxidative damage.

Steinbrenner H, Alili L, Bilgic E, Sies H, Brenneisen P.

Free Radic Biol Med. 2006 May 1;40(9):1513-23. Epub 2006 Jan 13.

PMID:
16632112
21.

Adaptive cellular protection against UVA-1-induced lipid peroxidation in human dermal fibroblasts shows donor-to-donor variability and is glutathione dependent.

Schneider LA, Dissemond J, Brenneisen P, Hainzl A, Briviba K, Wlaschek M, Scharffetter-Kochanek K.

Arch Dermatol Res. 2006 Jan;297(7):324-8. Epub 2005 Nov 18.

PMID:
16328346
22.

Selenium, oxidative stress, and health aspects.

Brenneisen P, Steinbrenner H, Sies H.

Mol Aspects Med. 2005 Aug-Oct;26(4-5):256-67. Review.

PMID:
16105679
23.

Tumor promoter TPA stimulates MMP-9 secretion from human keratinocytes by activation of superoxide-producing NADPH oxidase.

Steinbrenner H, Ramos MC, Stuhlmann D, Mitic D, Sies H, Brenneisen P.

Free Radic Res. 2005 Mar;39(3):245-53.

PMID:
15788229
24.

Loss of the tyrosyl radical in mouse ribonucleotide reductase by (-)-epicatechin.

Schroeder P, Voevodskaya N, Klotz LO, Brenneisen P, Gräslund A, Sies H.

Biochem Biophys Res Commun. 2005 Jan 21;326(3):614-7.

PMID:
15596143
25.

Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release.

Wenk J, Schüller J, Hinrichs C, Syrovets T, Azoitei N, Podda M, Wlaschek M, Brenneisen P, Schneider LA, Sabiwalsky A, Peters T, Sulyok S, Dissemond J, Schauen M, Krieg T, Wirth T, Simmet T, Scharffetter-Kochanek K.

J Biol Chem. 2004 Oct 29;279(44):45634-42. Epub 2004 Aug 10.

26.

Paracrine effect of TGF-beta1 on downregulation of gap junctional intercellular communication between human dermal fibroblasts.

Stuhlmann D, Steinbrenner H, Wendlandt B, Mitic D, Sies H, Brenneisen P.

Biochem Biophys Res Commun. 2004 Jun 25;319(2):321-6.

PMID:
15178409
27.

Induction of MMP-10 and MMP-1 in a squamous cell carcinoma cell line by ultraviolet radiation.

Ramos MC, Steinbrenner H, Stuhlmann D, Sies H, Brenneisen P.

Biol Chem. 2004 Jan;385(1):75-86.

PMID:
14977049
28.
29.

Long-term growth arrest of PUVA-treated fibroblasts in G2/M in the absence of p16(INK4a) p21(CIP1) or p53.

Ma W, Hommel C, Brenneisen P, Peters T, Smit N, Sedivy J, Scharffetter-Kochanek K, Wlaschek M.

Exp Dermatol. 2003 Oct;12(5):629-37.

PMID:
14705804
30.

Modulation of homologous gap junctional intercellular communication of human dermal fibroblasts via a paracrine factor(s) generated by squamous tumor cells.

Stuhlmann D, Ale-Agha N, Reinehr R, Steinbrenner H, Ramos MC, Sies H, Brenneisen P.

Carcinogenesis. 2003 Nov;24(11):1737-48. Epub 2003 Aug 29.

PMID:
12949050
31.

Protective and determining factors for the overall lipid peroxidation in ultraviolet A1-irradiated fibroblasts: in vitro and in vivo investigations.

Dissemond J, Schneider LA, Brenneisen P, Briviba K, Wenk J, Wlaschek M, Scharffetter-Kochanek K.

Br J Dermatol. 2003 Aug;149(2):341-9.

PMID:
12932241
32.

UVA-mediated downregulation of MMP-2 and MMP-9 in human epidermal keratinocytes.

Steinbrenner H, Ramos MC, Stuhlmann D, Sies H, Brenneisen P.

Biochem Biophys Res Commun. 2003 Aug 29;308(3):486-91.

PMID:
12914776
33.

Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events.

Brenneisen P, Sies H, Scharffetter-Kochanek K.

Ann N Y Acad Sci. 2002 Nov;973:31-43. Review.

PMID:
12485830
34.

Induction of manganese superoxide dismutase in human dermal fibroblasts: a UV-B-mediated paracrine mechanism with the release of epidermal interleukin 1 alpha, interleukin 1 beta, and tumor necrosis factor alpha.

Naderi-Hachtroudi L, Peters T, Brenneisen P, Meewes C, Hommel C, Razi-Wolf Z, Schneider LA, Schüller J, Wlaschek M, Scharffetter-Kochanek K.

Arch Dermatol. 2002 Nov;138(11):1473-9.

PMID:
12437453
35.

Essential role of an activator protein-2 (AP-2)/specificity protein 1 (Sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes.

Brenneisen P, Blaudschun R, Gille J, Schneider L, Hinrichs R, Wlaschek M, Eming S, Scharffetter-Kochanek K.

Biochem J. 2003 Jan 15;369(Pt 2):341-9.

36.

Beta 2 integrin-mediated adherence does not modulate superoxide anion release from neutrophils and subsequent lipid peroxidation of surrounding fibroblasts.

Dissemond J, Schneider LA, Brenneisen P, Peters T, Wlaschek M, Klein P, Hinrichs R, Scharffetter- Kochanek K.

Br J Dermatol. 2002 Aug;147(2):401-3. No abstract available.

PMID:
12174134
38.

Vascular endothelial growth factor causally contributes to the angiogenic response upon ultraviolet B irradiation in vivo.

Blaudschun R, Sunderkötter C, Brenneisen P, Hinrichs R, Peters T, Schneider L, Razi-Wolf Z, Hunzelmann N, Scharffetter-Kochanek K.

Br J Dermatol. 2002 Apr;146(4):581-7.

PMID:
11966687
39.

Human dermal fibroblasts escape from the long-term phenocopy of senescence induced by psoralen photoactivation.

Ma W, Wlaschek M, Brenneisen P, Schneider LA, Hommel C, Hellweg C, Sauer H, Wartenberg M, Herrmann G, Meewes C, Boukamp P, Scharffetter-Kochanek K.

Exp Cell Res. 2002 Apr 1;274(2):299-309.

PMID:
11900490
40.

Increased deposition of fibulin-2 in solar elastosis and its colocalization with elastic fibres.

Hunzelmann N, Nischt R, Brenneisen P, Eickert A, Krieg T.

Br J Dermatol. 2001 Aug;145(2):217-22.

PMID:
11531782
41.

Selective pick-up of increased iron by deferoxamine-coupled cellulose abrogates the iron-driven induction of matrix-degrading metalloproteinase 1 and lipid peroxidation in human dermal fibroblasts in vitro: a new dressing concept.

Wenk J, Foitzik A, Achterberg V, Sabiwalsky A, Dissemond J, Meewes C, Reitz A, Brenneisen P, Wlaschek M, Meyer-Ingold W, Scharffetter-Kochanek K.

J Invest Dermatol. 2001 Jun;116(6):833-9.

42.

UV-induced oxidative stress and photoaging.

Wenk J, Brenneisen P, Meewes C, Wlaschek M, Peters T, Blaudschun R, Ma W, Kuhr L, Schneider L, Scharffetter-Kochanek K.

Curr Probl Dermatol. 2001;29:83-94. Review. No abstract available.

PMID:
11225204
43.

Adaptive antioxidant response protects dermal fibroblasts from UVA-induced phototoxicity.

Meewes C, Brenneisen P, Wenk J, Kuhr L, Ma W, Alikoski J, Poswig A, Krieg T, Scharffetter-Kochanek K.

Free Radic Biol Med. 2001 Feb 1;30(3):238-47.

PMID:
11165870
44.

Isolation and identification of psoralen plus ultraviolet A (PUVA)-induced genes in human dermal fibroblasts by polymerase chain reaction-based subtractive hybridization.

Wlaschek M, Hommel C, Wenk J, Brenneisen P, Ma W, Herrmann G, Scharffetter-Kochanek K.

J Invest Dermatol. 2000 Nov;115(5):909-13.

45.

PCR-based subtractive hybridization identifies repressed genes in growth-arrested human dermal fibroblasts following combined treatment with 8-methoxypsoralen and UVA irradiation (PUVA).

Wlaschek M, Wenk J, Brenneisen P, Hommel C, Ma W, Herrmann G, Scharffetter-Kochanek K.

Exp Gerontol. 2000 Aug;35(5):573-81.

PMID:
10978679
46.

Discrete papular mucinosis-a rare subtype of lichen myxoedematosus.

Poswig A, Hinrichs R, Megahed M, Hunzelmann N, Kirchberg K, Brenneisen P, Krieg T, Scharffetter-Kochanek K.

Clin Exp Dermatol. 2000 Jun;25(4):289-92.

PMID:
10971487
47.

Adaptive antioxidant defence in human dermal fibroblasts.

Meewes C, Poswig A, Dissemond J, Brenneisen P, Scharffetter-Kochanek K.

Br J Dermatol. 2000 Sep;143(3):662-3. No abstract available.

PMID:
10971359
48.

Treatment of pruritus by capsaicin in a patient with pityriasis rubra pilaris receiving RE-PUVA therapy.

Neess CM, Hinrichs R, Dissemond J, Herrmann G, Poswig A, Servera-Llanras M, Hunzelmann N, Brenneisen P, Meewes C, Krieg T, Scharffetter-Kochanek K.

Clin Exp Dermatol. 2000 May;25(3):209-11.

PMID:
10844497
50.

Photoaging of the skin from phenotype to mechanisms.

Scharffetter-Kochanek K, Brenneisen P, Wenk J, Herrmann G, Ma W, Kuhr L, Meewes C, Wlaschek M.

Exp Gerontol. 2000 May;35(3):307-16. Review.

PMID:
10832052

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