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Items: 1 to 50 of 54

1.

Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4+ T Cells in Graft-versus-Host Disease.

Chung J, Radojcic V, Perkey E, Parnell TJ, Niknafs Y, Jin X, Friedman A, Labrecque N, Blazar BR, Brennan TV, Siebel CW, Maillard I.

J Immunol. 2019 Jul 15;203(2):557-568. doi: 10.4049/jimmunol.1900192. Epub 2019 Jun 10.

PMID:
31182480
2.

Mitochondria Released by Apoptotic Cell Death Initiate Innate Immune Responses.

Zhu M, Barbas AS, Lin L, Scheuermann U, Bishawi M, Brennan TV.

Immunohorizons. 2019 Jan;3(1):26-27. doi: 10.4049/immunohorizons.1800089. No abstract available.

3.

Mitochondria Released by Apoptotic Cell Death Initiate Innate Immune Responses.

Zhu M, Barbas AS, Lin L, Scheuermann U, Bishawi M, Brennan TV.

Immunohorizons. 2018 Dec;2(11):384-397. doi: 10.4049/immunohorizons.1800063.

4.

Circulating mitochondria in organ donors promote allograft rejection.

Lin L, Xu H, Bishawi M, Feng F, Samy K, Truskey G, Barbas AS, Kirk AD, Brennan TV.

Am J Transplant. 2019 Jul;19(7):1917-1929. doi: 10.1111/ajt.15309. Epub 2019 Mar 13.

PMID:
30761731
5.

Damage-Associated Molecular Patterns Induce Inflammatory Injury During Machine Preservation of the Liver: Potential Targets to Enhance a Promising Technology.

Scheuermann U, Zhu M, Song M, Yerxa J, Gao Q, Davis RP, Zhang M, Parker W, Hartwig MG, Kwun J, Brennan TV, Lee J, Barbas AS.

Liver Transpl. 2019 Apr;25(4):610-626. doi: 10.1002/lt.25429. Epub 2019 Mar 15.

6.

Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness: A Systematic Review.

Lubkin DT, Bishawi M, Barbas AS, Brennan TV, Kirk AD.

Crit Care Med. 2018 Dec;46(12):2018-2028. doi: 10.1097/CCM.0000000000003381.

PMID:
30113320
7.

Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction.

Pollara J, Edwards RW, Lin L, Bendersky VA, Brennan TV.

JCI Insight. 2018 Aug 9;3(15). pii: 121622. doi: 10.1172/jci.insight.121622. eCollection 2018 Aug 9.

8.

Heparan sulfate is a plasma biomarker of acute cellular allograft rejection.

Barbas AS, Lin L, McRae M, MacDonald AL, Truong T, Yang Y, Brennan TV.

PLoS One. 2018 Aug 7;13(8):e0200877. doi: 10.1371/journal.pone.0200877. eCollection 2018.

9.

Generation of Luciferase-expressing Tumor Cell Lines.

Brennan TV, Lin L, Huang X, Yang Y.

Bio Protoc. 2018 Apr 20;8(8). pii: e2817. doi: 10.21769/BioProtoc.2817.

10.

Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors.

Hammond E, Haynes NM, Cullinane C, Brennan TV, Bampton D, Handley P, Karoli T, Lanksheer F, Lin L, Yang Y, Dredge K.

J Immunother Cancer. 2018 Jun 14;6(1):54. doi: 10.1186/s40425-018-0363-5.

11.

Dendritic Cell Therapy in Transplantation, Phenotype Governs Destination and Function.

Samy KP, Brennan TV.

Transplantation. 2018 Oct;102(10):1593-1594. doi: 10.1097/TP.0000000000002238. No abstract available.

PMID:
29677071
12.

A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours.

Dredge K, Brennan TV, Hammond E, Lickliter JD, Lin L, Bampton D, Handley P, Lankesheer F, Morrish G, Yang Y, Brown MP, Millward M.

Br J Cancer. 2018 Apr;118(8):1035-1041. doi: 10.1038/s41416-018-0006-0. Epub 2018 Mar 13.

13.

Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers.

Weinhold KJ, Bukowski JF, Brennan TV, Noveck RJ, Staats JS, Lin L, Stempora L, Hammond C, Wouters A, Mojcik CF, Cheng J, Collinge M, Jesson MI, Hazra A, Biswas P, Lan S, Clark JD, Hodge JA.

Clin Immunol. 2018 Jun;191:10-20. doi: 10.1016/j.clim.2018.03.002. Epub 2018 Mar 5.

14.

IL-7 receptor heterogeneity as a mechanism for repertoire change during postdepletional homeostatic proliferation and its relation to costimulation blockade-resistant rejection.

Xu H, Bendersky VA, Brennan TV, Espinosa JR, Kirk AD.

Am J Transplant. 2018 Mar;18(3):720-730. doi: 10.1111/ajt.14589. Epub 2017 Dec 12.

15.

PD-L1 serves as a double agent in separating GVL from GVHD.

Brennan TV, Yang Y.

J Clin Invest. 2017 May 1;127(5):1627-1630. doi: 10.1172/JCI94196. Epub 2017 Apr 17.

16.

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.

Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Huang AY, Brennan TV, Bishop DK, Ludewig B, Siebel CW, Radtke F, Luther SA, Maillard I.

J Clin Invest. 2017 Apr 3;127(4):1574-1588. doi: 10.1172/JCI89535. Epub 2017 Mar 20.

17.

Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance.

Bracamonte-Baran W, Florentin J, Zhou Y, Jankowska-Gan E, Haynes WJ, Zhong W, Brennan TV, Dutta P, Claas FH, van Rood JJ, Burlingham WJ.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1099-1104. doi: 10.1073/pnas.1618364114. Epub 2017 Jan 17.

18.

Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation.

Brennan TV, Lin L, Brandstadter JD, Rendell VR, Dredge K, Huang X, Yang Y.

J Clin Invest. 2016 Jan;126(1):207-19. doi: 10.1172/JCI76566. Epub 2015 Dec 7.

19.

Innate immune activation by tissue injury and cell death in the setting of hematopoietic stem cell transplantation.

Brennan TV, Rendell VR, Yang Y.

Front Immunol. 2015 Mar 16;6:101. doi: 10.3389/fimmu.2015.00101. eCollection 2015. Review.

20.

Complete thymectomy in adult rats with non-invasive endotracheal intubation.

Rendell VR, Giamberardino C, Li J, Markert ML, Brennan TV.

J Vis Exp. 2014 Dec 29;(94). doi: 10.3791/52152.

21.

Renal outcomes of simultaneous liver-kidney transplantation compared to liver transplant alone for candidates with renal dysfunction.

Brennan TV, Lunsford KE, Vagefi PA, Bostrom A, Ma M, Feng S.

Clin Transplant. 2015 Jan;29(1):34-43. doi: 10.1111/ctr.12479. Epub 2014 Nov 17.

22.

May-Thurner syndrome complicating left-sided donor nephrectomy.

Rege AS, Rendell VR, Shrimal A, Engstrom BI, Miller MJ, Bashir MR, Brennan TV.

Transplantation. 2014 Apr 15;97(7):e40-1. doi: 10.1097/TP.0000000000000044. No abstract available.

PMID:
24686428
23.

Liver transplantation in an adolescent with acute liver failure from acute lymphoblastic leukemia.

Reddi DM, Barbas AS, Castleberry AW, Rege AS, Vikraman DS, Brennan TV, Ravindra KV, Collins BH, Sudan DL, Lagoo AS, Martin AE.

Pediatr Transplant. 2014 Mar;18(2):E57-63. doi: 10.1111/petr.12221. Epub 2014 Jan 20.

PMID:
24438382
24.

Fulminant herpes simplex viral hepatitis: ultrasound and CT imaging appearance and a review of the imaging literature.

Tripuraneni V, Patel K, Brennan TV, Ho LM.

Clin Imaging. 2014 Mar-Apr;38(2):191-4. doi: 10.1016/j.clinimag.2013.11.015. Epub 2013 Dec 4.

PMID:
24387920
25.

Renal transplant imaging using magnetic resonance angiography with a nonnephrotoxic contrast agent.

Bashir MR, Jaffe TA, Brennan TV, Patel UD, Ellis MJ.

Transplantation. 2013 Jul 15;96(1):91-6. doi: 10.1097/TP.0b013e318295464c.

PMID:
23680931
26.

Upregulation of IL-1β, IL-6, and CCL-2 by a novel mouse model of pancreatic ischemia-reperfusion injury.

Lunsford KE, Baird BJ, Sempowski GD, Cardona DM, Li Z, Weinhold KJ, Sudan DL, Brennan TV.

Transplantation. 2013 Apr 27;95(8):1000-7. doi: 10.1097/TP.0b013e318286483a.

27.

Posterior reversible encephalopathy syndrome independently associated with tacrolimus and sirolimus after multivisceral transplantation.

Barbas AS, Rege AS, Castleberry AW, Gommer J, Ellis MJ, Brennan TV, Collins BH, Martin AE, Ravindra KV, Vikraman DS, Sudan DL.

Am J Transplant. 2013 Mar;13(3):808-10. doi: 10.1111/ajt.12061. Epub 2013 Jan 17.

28.

Pneumatosis intestinalis: not always a surgical indication.

Zhang H, Jun SL, Brennan TV.

Case Rep Surg. 2012;2012:719713. doi: 10.1155/2012/719713. Epub 2012 Nov 12.

29.

Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation.

Brennan TV, Lin L, Huang X, Cardona DM, Li Z, Dredge K, Chao NJ, Yang Y.

Blood. 2012 Oct 4;120(14):2899-908. doi: 10.1182/blood-2011-07-368720. Epub 2012 Jul 3.

30.

Use of vascularized posterior rectus sheath allograft in pediatric multivisceral transplantation--report of two cases.

Ravindra KV, Martin AE, Vikraman DS, Brennan TV, Collins BH, Rege AS, Hollenbeck ST, Chinappa-Nagappa L, Eager K, Cousino D, Sudan DL.

Am J Transplant. 2012 Aug;12(8):2242-6. doi: 10.1111/j.1600-6143.2012.04088.x. Epub 2012 May 17.

31.

Derivation of non-infectious envelope proteins from virions isolated from plasma negative for HIV antibodies.

Vyas GN, Stoddart CA, Killian MS, Brennan TV, Goldberg T, Ziman A, Bryson Y.

Biologicals. 2012 Jan;40(1):15-20. doi: 10.1016/j.biologicals.2011.11.005. Epub 2011 Dec 20.

32.

Recent advances in immunosuppressive therapy for prevention of renal allograft rejection.

Lunsford KE, Barbas AS, Brennan TV.

Curr Opin Organ Transplant. 2011 Aug;16(4):390-7. doi: 10.1097/MOT.0b013e328348b420. Review.

PMID:
21666473
33.

Requirements for prolongation of allograft survival with regulatory T cell infusion in lymphosufficient hosts.

Brennan TV, Tang Q, Liu FC, Hoang V, Bi M, Bluestone JA, Kang SM.

J Surg Res. 2011 Jul;169(1):e69-75. doi: 10.1016/j.jss.2011.03.021. Epub 2011 Apr 5.

34.

Innate pathways of immune activation in transplantation.

Brennan TV, Lunsford KE, Kuo PC.

J Transplant. 2010;2010. pii: 826240. doi: 10.1155/2010/826240. Epub 2010 Aug 31.

35.

Preferential priming of alloreactive T cells with indirect reactivity.

Brennan TV, Jaigirdar A, Hoang V, Hayden T, Liu FC, Zaid H, Chang CK, Bucy RP, Tang Q, Kang SM.

Am J Transplant. 2009 Apr;9(4):709-18. doi: 10.1111/j.1600-6143.2009.02578.x.

36.

A new T-cell receptor transgenic model of the CD4+ direct pathway: level of priming determines acute versus chronic rejection.

Brennan TV, Hoang V, Garrod KR, Liu FC, Hayden T, Kim J, Kang SM.

Transplantation. 2008 Jan 27;85(2):247-55. doi: 10.1097/TP.0b013e31815e883e.

PMID:
18212630
37.

Optimizing living donor kidney graft function by donor-recipient pair selection.

Brennan TV, Bostrom A, Feng S.

Transplantation. 2006 Sep 15;82(5):651-6.

PMID:
16969288
38.

Living donor kidney transplant recipients and clinical trials: participation profiles and impact on post-transplant care.

Brennan TV, Fuller TF, Vincenti F, Chan S, Chang CK, Bostrom A, Zlatunich JK, Tomlanovich SJ, Feng S.

Am J Transplant. 2006 Oct;6(10):2429-35. Epub 2006 Aug 21.

39.

Targeted lymphoid homing of dendritic cells is required for prolongation of allograft survival.

Garrod KR, Chang CK, Liu FC, Brennan TV, Foster RD, Kang SM.

J Immunol. 2006 Jul 15;177(2):863-8.

40.

End stage polycystic kidney disease: indications and timing of native nephrectomy relative to kidney transplantation.

Fuller TF, Brennan TV, Feng S, Kang SM, Stock PG, Freise CE.

J Urol. 2005 Dec;174(6):2284-8.

PMID:
16280813
41.

Increased rejection in living unrelated versus living related kidney transplants does not affect short-term function and survival.

Fuller TF, Feng S, Brennan TV, Tomlanovich S, Bostrom A, Freise CE.

Transplantation. 2004 Oct 15;78(7):1030-5.

PMID:
15480170
42.

Early graft function after living donor kidney transplantation predicts rejection but not outcomes.

Brennan TV, Freise CE, Fuller TF, Bostrom A, Tomlanovich SJ, Feng S.

Am J Transplant. 2004 Jun;4(6):971-9.

43.

Optimizing the use of cyclosporine (Neoral) for recipients of living donor kidneys.

Vincenti F, Brennan TV, Fuller TF, Feng S.

Transplant Proc. 2004 Mar;36(2 Suppl):50S-53S. No abstract available.

PMID:
15041306
45.

Congenital cleft spleen with CT scan appearance of high-grade splenic laceration after blunt abdominal trauma.

Brennan TV, Lipshutz GS, Posselt AM, Horn JK.

J Emerg Med. 2003 Aug;25(2):139-42.

PMID:
12901998
46.

Novel microlaparoscopic technique for peritoneal dialysis catheter placement.

Yun EJ, Meng MV, Brennan TV, McAninch JW, Santucci RA, Rogers SJ.

Urology. 2003 May;61(5):1026-8.

PMID:
12736031
47.

Thorotrast-induced liver neoplasia: a collective review.

Lipshutz GS, Brennan TV, Warren RS.

J Am Coll Surg. 2002 Nov;195(5):713-8. Review. No abstract available.

PMID:
12437262
48.

Laparoscopic treatment of acute mesenteric torsion.

Brennan TV, Horn JK, Stollman NH.

Surg Endosc. 2002 Jun;16(6):1004. Epub 2002 Mar 18.

PMID:
12163972
49.

Total mesenteric excision in the treatment of rectal carcinoma: methods and outcomes.

Brennan TV, Lipshutz GS, Gibbs VC, Norton JA.

Surg Oncol. 2002 May;10(4):171-6. Review. No abstract available.

PMID:
12020671
50.

Late thrombosis of the native aortic root after Norwood reconstruction for hypoplastic left heart syndrome.

Brennan TV, Rodefeld MD, Tacy TA, Reddy VM, Hanley FL.

J Thorac Cardiovasc Surg. 2001 Mar;121(3):580-2. No abstract available.

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