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Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4+ T Cells in Graft-versus-Host Disease.

Chung J, Radojcic V, Perkey E, Parnell TJ, Niknafs Y, Jin X, Friedman A, Labrecque N, Blazar BR, Brennan TV, Siebel CW, Maillard I.

J Immunol. 2019 Jul 15;203(2):557-568. doi: 10.4049/jimmunol.1900192. Epub 2019 Jun 10.


Aetna's Compassionate Care Program: Sustained Value for Our Members with Advanced Illness.

Baquet-Simpson A, Spettell CM, Freeman AN, Bates AM, Paz HL, Mirsky R, Knecht DB, Brennan TA.

J Palliat Med. 2019 Jun 10. doi: 10.1089/jpm.2018.0359. [Epub ahead of print]


Quantifying driver cell phone use at signalized intersections using software-defined radio.

Brennan TM Jr, Jesson JE, Furlanetto PGA.

Traffic Inj Prev. 2019;20(4):359-364. doi: 10.1080/15389588.2019.1592167. Epub 2019 Apr 30.


Mitochondria Released by Apoptotic Cell Death Initiate Innate Immune Responses.

Zhu M, Barbas AS, Lin L, Scheuermann U, Bishawi M, Brennan TV.

Immunohorizons. 2019 Jan;3(1):26-27. doi: 10.4049/immunohorizons.1800089. No abstract available.


Mitochondria Released by Apoptotic Cell Death Initiate Innate Immune Responses.

Zhu M, Barbas AS, Lin L, Scheuermann U, Bishawi M, Brennan TV.

Immunohorizons. 2018 Dec;2(11):384-397. doi: 10.4049/immunohorizons.1800063.


Circulating mitochondria in organ donors promote allograft rejection.

Lin L, Xu H, Bishawi M, Feng F, Samy K, Truskey G, Barbas AS, Kirk AD, Brennan TV.

Am J Transplant. 2019 Jul;19(7):1917-1929. doi: 10.1111/ajt.15309. Epub 2019 Mar 13.


Damage-Associated Molecular Patterns Induce Inflammatory Injury During Machine Preservation of the Liver: Potential Targets to Enhance a Promising Technology.

Scheuermann U, Zhu M, Song M, Yerxa J, Gao Q, Davis RP, Zhang M, Parker W, Hartwig MG, Kwun J, Brennan TV, Lee J, Barbas AS.

Liver Transpl. 2019 Apr;25(4):610-626. doi: 10.1002/lt.25429. Epub 2019 Mar 15.


Congenital infantile fibrosarcoma of the glabella: Nuances of achieving surgical cure without cosmetic or functional deformity.

Nicholas RG, Brennan TE.

Int J Pediatr Otorhinolaryngol. 2019 Feb;117:110-114. doi: 10.1016/j.ijporl.2018.10.020. Epub 2018 Oct 13. Review.


Video-assisted thoracoscopic surgery versus robotic-assisted thoracoscopic surgery and postoperative opioid consumption.

Bayman EO, Brennan TJ.

J Thorac Dis. 2018 Sep;10(Suppl 26):S3222-S3223. doi: 10.21037/jtd.2018.08.16. No abstract available.


Advancing the Science of Healthcare Service Delivery: The NHLBI Corporate Healthcare Leaders' Panel.

Sampson UKA, McGlynn EA, Perlin JB, Frisse ME, Arnold SB, Benz EJ Jr, Brennan T, Briss P, Beeuwkes Buntin MJ, Khosla S, King RG, Kuntz R, Leider H, Ling SM, Macrae J, Murray R, Thrailkill E, Wager C, Witchey D, Jacobson HR.

Glob Heart. 2018 Dec;13(4):339-345. doi: 10.1016/j.gheart.2018.09.508. Epub 2018 Oct 6. Review.


Deep Tissue Incision Enhances Spinal Dorsal Horn Neuron Activity During Static Isometric Muscle Contraction in Rats.

Gu H, Sugiyama D, Kang S, Brennan TJ.

J Pain. 2019 Mar;20(3):301-314. doi: 10.1016/j.jpain.2018.09.012. Epub 2018 Oct 6.


Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness: A Systematic Review.

Lubkin DT, Bishawi M, Barbas AS, Brennan TV, Kirk AD.

Crit Care Med. 2018 Dec;46(12):2018-2028. doi: 10.1097/CCM.0000000000003381.


Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction.

Pollara J, Edwards RW, Lin L, Bendersky VA, Brennan TV.

JCI Insight. 2018 Aug 9;3(15). pii: 121622. doi: 10.1172/jci.insight.121622. eCollection 2018 Aug 9.


Heparan sulfate is a plasma biomarker of acute cellular allograft rejection.

Barbas AS, Lin L, McRae M, MacDonald AL, Truong T, Yang Y, Brennan TV.

PLoS One. 2018 Aug 7;13(8):e0200877. doi: 10.1371/journal.pone.0200877. eCollection 2018.


Adult supraglottitis: a life-threatening disease and potential airway emergency.

Brennan T, McCabe A, Hennessy A.

BMJ Case Rep. 2018 Jul 13;2018. pii: bcr-2018-225761. doi: 10.1136/bcr-2018-225761. No abstract available.


Opioid Use Disorder, Stigma, and Transplantation: A Call to Action.

Wakeman SE, Ladin K, Brennan T, Chung RT.

Ann Intern Med. 2018 Aug 7;169(3):188-189. doi: 10.7326/M18-1099. Epub 2018 Jul 10. No abstract available.


Generation of Luciferase-expressing Tumor Cell Lines.

Brennan TV, Lin L, Huang X, Yang Y.

Bio Protoc. 2018 Apr 20;8(8). pii: e2817. doi: 10.21769/BioProtoc.2817.


Effect of Thoracic Epidural Anesthesia in a Rat Model of Phrenic Motor Inhibition after Upper Abdominal Surgery.

Chae WS, Choi S, Sugiyama D, Richerson GB, Brennan TJ, Kang S.

Anesthesiology. 2018 Oct;129(4):791-807. doi: 10.1097/ALN.0000000000002331.


Ovine model of neuropathic pain for assessing mechanisms of spinal cord stimulation therapy via dorsal horn recordings, von Frey filaments, and gait analysis.

Reddy CG, Miller JW, Abode-Iyamah KO, Safayi S, Wilson S, Dalm BD, Fredericks DC, Gillies GT, Howard MA 3rd, Brennan TJ.

J Pain Res. 2018 Jun 15;11:1147-1162. doi: 10.2147/JPR.S139843. eCollection 2018.


Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.

Clark TA, Chung JH, Kennedy M, Hughes JD, Chennagiri N, Lieber DS, Fendler B, Young L, Zhao M, Coyne M, Breese V, Young G, Donahue A, Pavlick D, Tsiros A, Brennan T, Zhong S, Mughal T, Bailey M, He J, Roels S, Frampton GM, Spoerke JM, Gendreau S, Lackner M, Schleifman E, Peters E, Ross JS, Ali SM, Miller VA, Gregg JP, Stephens PJ, Welsh A, Otto GA, Lipson D.

J Mol Diagn. 2018 Sep;20(5):686-702. doi: 10.1016/j.jmoldx.2018.05.004. Epub 2018 Jun 22.


Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors.

Hammond E, Haynes NM, Cullinane C, Brennan TV, Bampton D, Handley P, Karoli T, Lanksheer F, Lin L, Yang Y, Dredge K.

J Immunother Cancer. 2018 Jun 14;6(1):54. doi: 10.1186/s40425-018-0363-5.


Preoperative Patient Expectations of Postoperative Pain Are Associated with Moderate to Severe Acute Pain After VATS.

Bayman EO, Parekh KR, Keech J, Larson N, Vander Weg M, Brennan TJ.

Pain Med. 2019 Mar 1;20(3):543-554. doi: 10.1093/pm/pny096.


Pain after surgery.

Eisenach JC, Brennan TJ.

Pain. 2018 Jun;159(6):1010-1011. doi: 10.1097/j.pain.0000000000001223. No abstract available.


Dendritic Cell Therapy in Transplantation, Phenotype Governs Destination and Function.

Samy KP, Brennan TV.

Transplantation. 2018 Oct;102(10):1593-1594. doi: 10.1097/TP.0000000000002238. No abstract available.


Feasibility of Training Physical Therapists to Implement a Psychologically Informed Physical Therapy Program for Deployed U.S. Sailors and Marines with Musculoskeletal Injuries.

Weiser S, Lis A, Ziemke G, Hiebert R, Faulkner D, Brennan T, Iveson B, Campello M.

Mil Med. 2018 Mar 1;183(suppl_1):503-509. doi: 10.1093/milmed/usx229. Erratum in: Mil Med. 2018 Nov 1;183(11-12):332.


Partners and Alerts in Medication Adherence: A Randomized Clinical Trial.

Kessler JB, Troxel AB, Asch DA, Mehta SJ, Marcus N, Lim R, Zhu J, Shrank W, Brennan T, Volpp KG.

J Gen Intern Med. 2018 Sep;33(9):1536-1542. doi: 10.1007/s11606-018-4389-7. Epub 2018 Mar 15.


A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours.

Dredge K, Brennan TV, Hammond E, Lickliter JD, Lin L, Bampton D, Handley P, Lankesheer F, Morrish G, Yang Y, Brown MP, Millward M.

Br J Cancer. 2018 Apr;118(8):1035-1041. doi: 10.1038/s41416-018-0006-0. Epub 2018 Mar 13.


Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers.

Weinhold KJ, Bukowski JF, Brennan TV, Noveck RJ, Staats JS, Lin L, Stempora L, Hammond C, Wouters A, Mojcik CF, Cheng J, Collinge M, Jesson MI, Hazra A, Biswas P, Lan S, Clark JD, Hodge JA.

Clin Immunol. 2018 Jun;191:10-20. doi: 10.1016/j.clim.2018.03.002. Epub 2018 Mar 5.


Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane.

Wang Z, Gurule EE, Brennan TP, Gerold JM, Kwon KJ, Hosmane NN, Kumar MR, Beg SA, Capoferri AA, Ray SC, Ho YC, Hill AL, Siliciano JD, Siliciano RF.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2575-E2584. doi: 10.1073/pnas.1720665115. Epub 2018 Feb 26.


Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.

Aumailley L, Dubois MJ, Brennan TA, Garand C, Paquet ER, Pignolo RJ, Marette A, Lebel M.

FASEB J. 2018 Jul;32(7):3623-3640. doi: 10.1096/fj.201701176R. Epub 2018 Feb 8.


Response to "VATS vs. thoracotomy regarding postoperative chronic pain".

Bayman EO, Parekh KR, Keech J, Brennan TJ.

J Thorac Dis. 2017 Dec;9(12):E1151-E1153. doi: 10.21037/jtd.2017.11.27. No abstract available.


Response to "Editorial on pain following thoracic surgery".

Bayman EO, Parekh KR, Keech J, Brennan TJ.

J Thorac Dis. 2017 Dec;9(12):E1154-E1155. doi: 10.21037/jtd.2017.11.74. No abstract available.


Analytic tractography: A closed-form solution for estimating local white matter connectivity with diffusion MRI.

Cieslak M, Brennan T, Meiring W, Volz LJ, Greene C, Asturias A, Suri S, Grafton ST.

Neuroimage. 2018 Apr 1;169:473-484. doi: 10.1016/j.neuroimage.2017.12.039. Epub 2017 Dec 22.


In Reply.

Bayman EO, Brennan TJ.

Anesthesiology. 2018 Jan;128(1):225. doi: 10.1097/ALN.0000000000001944. No abstract available.


IL-7 receptor heterogeneity as a mechanism for repertoire change during postdepletional homeostatic proliferation and its relation to costimulation blockade-resistant rejection.

Xu H, Bendersky VA, Brennan TV, Espinosa JR, Kirk AD.

Am J Transplant. 2018 Mar;18(3):720-730. doi: 10.1111/ajt.14589. Epub 2017 Dec 12.


Automatable algorithms to identify nonmedical opioid use using electronic data: a systematic review.

Canan C, Polinski JM, Alexander GC, Kowal MK, Brennan TA, Shrank WH.

J Am Med Inform Assoc. 2017 Nov 1;24(6):1204-1210. doi: 10.1093/jamia/ocx066. Review.


Cartilage-derived retinoic acid-sensitive protein (CD-RAP): A stage-specific biomarker of heterotopic endochondral ossification (HEO) in fibrodysplasia ossificans progressiva (FOP).

Lindborg CM, Brennan TA, Wang H, Kaplan FS, Pignolo RJ.

Bone. 2018 Apr;109:153-157. doi: 10.1016/j.bone.2017.09.016. Epub 2017 Sep 28.


Nutritional State and Feeding Behaviors of Children With Eosinophilic Esophagitis and Gastroesophageal Reflux Disease.

Mehta P, Furuta GT, Brennan T, Henry ML, Maune NC, Sundaram SS, Menard-Katcher C, Atkins D, Takurukura F, Giffen S, Pan Z, Haas AM.

J Pediatr Gastroenterol Nutr. 2018 Apr;66(4):603-608. doi: 10.1097/MPG.0000000000001741.


Mast cell inhibition as a therapeutic approach in fibrodysplasia ossificans progressiva (FOP).

Brennan TA, Lindborg CM, Bergbauer CR, Wang H, Kaplan FS, Pignolo RJ.

Bone. 2018 Apr;109:259-266. doi: 10.1016/j.bone.2017.08.023. Epub 2017 Aug 26.


The Temporalis Muscle Flap for Palate Reconstruction: Case Series and Review of the Literature.

Brennan T, Tham TM, Costantino P.

Int Arch Otorhinolaryngol. 2017 Jul;21(3):259-264. doi: 10.1055/s-0037-1598653. Epub 2017 Feb 17.


Home infusion: Safe, clinically effective, patient preferred, and cost saving.

Polinski JM, Kowal MK, Gagnon M, Brennan TA, Shrank WH.

Healthc (Amst). 2017 Mar;5(1-2):68-80. doi: 10.1016/j.hjdsi.2016.04.004. Epub 2016 Apr 29. Review.


Hydrogen Peroxide Induces Muscle Nociception via Transient Receptor Potential Ankyrin 1 Receptors.

Sugiyama D, Kang S, Arpey N, Arunakul P, Usachev YM, Brennan TJ.

Anesthesiology. 2017 Oct;127(4):695-708. doi: 10.1097/ALN.0000000000001756.


Economic value of pharmacist-led medication reconciliation for reducing medication errors after hospital discharge.

Najafzadeh M, Schnipper JL, Shrank WH, Kymes S, Brennan TA, Choudhry NK.

Am J Manag Care. 2016 Oct;22(10):654-661.


The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.

Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC 3rd, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G.

J Pain. 2017 May;18(5):479-489. doi: 10.1016/j.jpain.2017.02.421.


The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.

Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC 3rd, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G.

Pain Med. 2017 May 1;18(5):947-958. doi: 10.1093/pm/pnx019.


Association Between Academic Medical Center Pharmaceutical Detailing Policies and Physician Prescribing.

Larkin I, Ang D, Steinhart J, Chao M, Patterson M, Sah S, Wu T, Schoenbaum M, Hutchins D, Brennan T, Loewenstein G.

JAMA. 2017 May 2;317(17):1785-1795. doi: 10.1001/jama.2017.4039.


PD-L1 serves as a double agent in separating GVL from GVHD.

Brennan TV, Yang Y.

J Clin Invest. 2017 May 1;127(5):1627-1630. doi: 10.1172/JCI94196. Epub 2017 Apr 17.


Predicting 1-Year Statin Adherence Among Prevalent Users: A Retrospective Cohort Study.

Krumme AA, Franklin JM, Isaman DL, Matlin OS, Tong AY, Spettell CM, Brennan TA, Shrank WH, Choudhry NK.

J Manag Care Spec Pharm. 2017 Apr;23(4):494-502. doi: 10.18553/jmcp.2017.23.4.494.


Pain-Related Limitations in Daily Activities Following Thoracic Surgery in a United States Population.

Bayman EO, Lennertz R, Brennan TJ.

Pain Physician. 2017 Mar;20(3):E367-E378.

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