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The prescription opioid conundrum: 21st century solutions to a millennia-long problem.

Brennan MJ, Gudin JA.

Postgrad Med. 2019 Oct 20:1-11. doi: 10.1080/00325481.2019.1677383. [Epub ahead of print]


Bridging gaps in heart valve disease care: Opportunities for quality improvement.

Brennan MJ, Coylewright M, Ayo-Vaughan M, Ganesan N.

Catheter Cardiovasc Interv. 2019 Aug 1;94(2):289-293. doi: 10.1002/ccd.28371. Epub 2019 Jun 24.


Speech and Language Outcomes in Patients with Ankyloglossia Undergoing Frenulectomy: A Retrospective Pilot Study.

Daggumati S, Cohn JE, Brennan MJ, Evarts M, McKinnon BJ, Terk AR.

OTO Open. 2019 Feb 11;3(1):2473974X19826943. doi: 10.1177/2473974X19826943. eCollection 2019 Jan-Mar.


An Acute Care for Elders Quality Improvement Program for Complex, High-Cost Patients Yields Savings for the System.

Brennan MJ, Knee AB, Leahy EJ, Ehresman MJ, Courtney HA, Coffelt P, Stefan MS.

J Hosp Med. 2019 May 12;14:E1-E7. doi: 10.12788/jhm.3198. [Epub ahead of print]


Caregiver perception of speech quality in patients with ankyloglossia: Comparison between surgery and non-treatment.

Daggumati S, Cohn JE, Brennan MJ, Evarts M, McKinnon BJ, Terk AR.

Int J Pediatr Otorhinolaryngol. 2019 Apr;119:70-74. doi: 10.1016/j.ijporl.2019.01.019. Epub 2019 Jan 18.


Adaptive Phase Transform Method for Pipeline Leakage Detection.

Ma Y, Gao Y, Cui X, Brennan MJ, Almeida FCL, Yang J.

Sensors (Basel). 2019 Jan 14;19(2). pii: E310. doi: 10.3390/s19020310.


Critical factors for the bulk adhesion of engineered elastomeric proteins.

Brennan MJ, Hollingshead SE, Wilker JJ, Liu JC.

R Soc Open Sci. 2018 May 9;5(5):171225. doi: 10.1098/rsos.171225. eCollection 2018 May.


The Association of Frailty with Discharge Disposition for Hospitalized Community Dwelling Elderly Patients.

Ramdass SK, Brennan MJ, Starr R, Lindenauer PK, Liu X, Pekow P, Stefan MS.

J Hosp Med. 2018 Mar 1;13(3):182-184. doi: 10.12788/jhm.2890. Epub 2017 Dec 6.


Reduction of opioid use and improvement in chronic pain in opioid-experienced patients after topical analgesic treatment: an exploratory analysis.

Gudin JA, Brennan MJ, Harris ED, Hurwitz PL, Dietze DT, Strader JD.

Postgrad Med. 2018 Jan;130(1):42-51. doi: 10.1080/00325481.2018.1414551.


The comparative pharmacokinetics of physical manipulation by crushing of Xtampza® ER compared with OxyContin®.

Brennan MJ, Kopecky EA, Marseilles A, O'Connor M, Fleming AB.

Pain Manag. 2017 Nov;7(6):461-472. doi: 10.2217/pmt-2017-0030. Epub 2017 Sep 18.


A New Whooping Cough Vaccine That May Prevent Colonization and Transmission.

Brennan MJ.

Vaccines (Basel). 2017 Nov 10;5(4). pii: E43. doi: 10.3390/vaccines5040043.


PE and PPE Genes: A Tale of Conservation and Diversity.

Delogu G, Brennan MJ, Manganelli R.

Adv Exp Med Biol. 2017;1019:191-207. doi: 10.1007/978-3-319-64371-7_10. Review.


Biofilms and Mycobacterium tuberculosis.

Brennan MJ.

Infect Immun. 2017 Sep 20;85(10). pii: e00411-17. doi: 10.1128/IAI.00411-17. Print 2017 Oct. No abstract available.


Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population.

Baguma R, Penn-Nicholson A, Smit E, Erasmus M, Day J, Makhethe L, de Kock M, Hughes EJ, van Rooyen M, Pienaar B, Stone L, Hanekom W, Brennan MJ, Wallis RS, Hatherill M, Scriba TJ.

PLoS One. 2017 Sep 8;12(9):e0184563. doi: 10.1371/journal.pone.0184563. eCollection 2017.


The Cross-Species Mycobacterial Growth Inhibition Assay (MGIA) Project, 2010-2014.

Brennan MJ, Tanner R, Morris S, Scriba TJ, Achkar JM, Zelmer A, Hokey DA, Izzo A, Sharpe S, Williams A, Penn-Nicholson A, Erasmus M, Stylianou E, Hoft DF, McShane H, Fletcher HA.

Clin Vaccine Immunol. 2017 Sep 5;24(9). pii: e00142-17. doi: 10.1128/CVI.00142-17. Print 2017 Sep. Review.


Circumstances of fall-related injuries by age and gender among community-dwelling adults in the United States.

Timsina LR, Willetts JL, Brennan MJ, Marucci-Wellman H, Lombardi DA, Courtney TK, Verma SK.

PLoS One. 2017 May 4;12(5):e0176561. doi: 10.1371/journal.pone.0176561. eCollection 2017.


The Enigmatic PE/PPE Multigene Family of Mycobacteria and Tuberculosis Vaccination.

Brennan MJ.

Infect Immun. 2017 May 23;85(6). pii: e00969-16. doi: 10.1128/IAI.00969-16. Print 2017 Jun. Review.


A bioinspired elastin-based protein for a cytocompatible underwater adhesive.

Brennan MJ, Kilbride BF, Wilker JJ, Liu JC.

Biomaterials. 2017 Apr;124:116-125. doi: 10.1016/j.biomaterials.2017.01.034. Epub 2017 Jan 30.


Strategies for Combating Opioid-Induced Constipation: Targeted Mechanisms to Maintain Pain Control Without Compromise.

Brennan MJ, Stanos SP.

PM R. 2017 Mar;9(3):325. doi: 10.1016/j.pmrj.2017.01.003. Epub 2017 Jan 29.


Long-term outcomes of elders discharged on antipsychotics.

Loh KP, Ramdass S, Garb JL, Thim M, Brennan MJ, Lindenauer PK, Lagu T.

J Hosp Med. 2016 Aug;11(8):550-5. doi: 10.1002/jhm.2585. Epub 2016 Apr 6.


Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction.

Chen T, Blanc C, Eder AZ, Prados-Rosales R, Souza AC, Kim RS, Glatman-Freedman A, Joe M, Bai Y, Lowary TL, Tanner R, Brennan MJ, Fletcher HA, McShane H, Casadevall A, Achkar JM.

J Infect Dis. 2016 Jul 15;214(2):300-10. doi: 10.1093/infdis/jiw141. Epub 2016 Apr 7.


Combining statistics from two national complex surveys to estimate injury rates per hour exposed and variance by activity in the USA.

Lin TC, Marucci-Wellman HR, Willetts JL, Brennan MJ, Verma SK.

Inj Prev. 2016 Dec;22(6):427-431. doi: 10.1136/injuryprev-2015-041885. Epub 2016 Apr 4.


PE_PGRS33 Contributes to Mycobacterium tuberculosis Entry in Macrophages through Interaction with TLR2.

Palucci I, Camassa S, Cascioferro A, Sali M, Anoosheh S, Zumbo A, Minerva M, Iantomasi R, De Maio F, Di Sante G, Ria F, Sanguinetti M, Palù G, Brennan MJ, Manganelli R, Delogu G.

PLoS One. 2016 Mar 15;11(3):e0150800. doi: 10.1371/journal.pone.0150800. eCollection 2016.


Cytocompatibility studies of a biomimetic copolymer with simplified structure and high-strength adhesion.

Brennan MJ, Meredith HJ, Jenkins CL, Wilker JJ, Liu JC.

J Biomed Mater Res A. 2016 Apr;104(4):983-90. doi: 10.1002/jbm.a.35633. Epub 2016 Jan 20.


Opioid abuse-deterrent strategies: role of clinicians in acute pain management.

Webster LR, Brennan MJ, Kwong LM, Levandowski R, Gudin JA.

Postgrad Med. 2016 Jan;128(1):76-84. doi: 10.1080/00325481.2016.1113841. Epub 2015 Dec 3. Review.


Consensus Recommendations on Initiating Prescription Therapies for Opioid-Induced Constipation.

Argoff CE, Brennan MJ, Camilleri M, Davies A, Fudin J, Galluzzi KE, Gudin J, Lembo A, Stanos SP, Webster LR.

Pain Med. 2015 Dec;16(12):2324-37. doi: 10.1111/pme.12937. Epub 2015 Nov 19. Review.


Leisure-Time Physical Activity, Falls, and Fall Injuries in Middle-Aged Adults.

Caban-Martinez AJ, Courtney TK, Chang WR, Lombardi DA, Huang YH, Brennan MJ, Perry MJ, Katz JN, Christiani DC, Verma SK.

Am J Prev Med. 2015 Dec;49(6):888-901. doi: 10.1016/j.amepre.2015.05.022. Epub 2015 Jul 29.


Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32.

Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Perez-Acle T, Skerrett IM.

J Biol Chem. 2015 Jul 10;290(28):17074-84. doi: 10.1074/jbc.M115.650747. Epub 2015 May 12.


Elderly-onset neuromyelitis optica spectrum disorders.

Loh KP, Brennan MJ.

J Am Geriatr Soc. 2015 Feb;63(2):411-2. doi: 10.1111/jgs.13266. No abstract available.


From hospital to community: use of antipsychotics in hospitalized elders.

Loh KP, Ramdass S, Garb JL, Brennan MJ, Lindenauer PK, Lagu T.

J Hosp Med. 2014 Dec;9(12):802-4. doi: 10.1002/jhm.2277. Epub 2014 Oct 24. No abstract available.


An unusual cause of delirium and debility: refractory hypercalcemia in a man with B-cell prolymphocytic leukemia.

Loh KP, Dahiya S, Brennan MJ.

J Am Geriatr Soc. 2014 Oct;62(10):2021-2. doi: 10.1111/jgs.13055. No abstract available.


Preventing slips and falls through leisure-time physical activity: findings from a study of limited-service restaurants.

Caban-Martinez AJ, Courtney TK, Chang WR, Lombardi DA, Huang YH, Brennan MJ, Perry MJ, Katz JN, Verma SK.

PLoS One. 2014 Oct 16;9(10):e110248. doi: 10.1371/journal.pone.0110248. eCollection 2014.


Duration of slip-resistant shoe usage and the rate of slipping in limited-service restaurants: results from a prospective and crossover study.

Verma SK, Zhao Z, Courtney TK, Chang WR, Lombardi DA, Huang YH, Brennan MJ, Perry MJ.

Ergonomics. 2014;57(12):1919-26. doi: 10.1080/00140139.2014.952348. Epub 2014 Sep 10.


Differences in time use and activity patterns when adding a second job: implications for health and safety in the United States.

Marucci-Wellman HR, Lin TC, Willetts JL, Brennan MJ, Verma SK.

Am J Public Health. 2014 Aug;104(8):1488-500. doi: 10.2105/AJPH.2014.301921. Epub 2014 Jun 12.


The nuances of age as an outcome predictor.

Higgins TL, Brennan MJ.

Rev Clin Esp (Barc). 2014 Mar;214(2):85-6. doi: 10.1016/j.rce.2013.11.006. Epub 2013 Dec 20. No abstract available.


Novel licensure pathways for expeditious introduction of new tuberculosis vaccines: a discussion of the adaptive licensure concept.

Rustomjee R, Lockhart S, Shea J, Fourie PB, Hindle Z, Steel G, Hussey G, Ginsberg A, Brennan MJ.

Tuberculosis (Edinb). 2014 Mar;94(2):178-82. doi: 10.1016/ Epub 2013 Dec 8.


Critical research concepts in tuberculosis vaccine development.

Delogu G, Manganelli R, Brennan MJ.

Clin Microbiol Infect. 2014 May;20 Suppl 5:59-65. doi: 10.1111/1469-0691.12460. Epub 2014 Jan 20. Review.


Internet and telephonic IVR mixed-mode survey for longitudinal studies: choice, retention, and data equivalency.

Verma SK, Courtney TK, Lombardi DA, Chang WR, Huang YH, Brennan MJ, Perry MJ.

Ann Epidemiol. 2014 Jan;24(1):72-4. doi: 10.1016/j.annepidem.2013.10.004. Epub 2013 Oct 14.


Work in multiple jobs and the risk of injury in the US working population.

Marucci-Wellman HR, Willetts JL, Lin TC, Brennan MJ, Verma SK.

Am J Public Health. 2014 Jan;104(1):134-42. doi: 10.2105/AJPH.2013.301431. Epub 2013 Nov 14.


Inhibition of mycobacterial growth in vitro following primary but not secondary vaccination with Mycobacterium bovis BCG.

Fletcher HA, Tanner R, Wallis RS, Meyer J, Manjaly ZR, Harris S, Satti I, Silver RF, Hoft D, Kampmann B, Walker KB, Dockrell HM, Fruth U, Barker L, Brennan MJ, McShane H.

Clin Vaccine Immunol. 2013 Nov;20(11):1683-9. doi: 10.1128/CVI.00427-13. Epub 2013 Aug 28.


Update on prescription extended-release opioids and appropriate patient selection.

Brennan MJ.

J Multidiscip Healthc. 2013 Jul 23;6:265-80. doi: 10.2147/JMDH.S38562. Print 2013.


Prescription opioid abuse: challenges and opportunities for payers.

Katz NP, Birnbaum H, Brennan MJ, Freedman JD, Gilmore GP, Jay D, Kenna GA, Madras BK, McElhaney L, Weiss RD, White AG.

Am J Manag Care. 2013 Apr;19(4):295-302.


Preventive vaccines for tuberculosis.

Evans TG, Brennan MJ, Barker L, Thole J.

Vaccine. 2013 Apr 18;31 Suppl 2:B223-6. doi: 10.1016/j.vaccine.2012.11.081. Review.


Brief report: citrullination within the atherosclerotic plaque: a potential target for the anti-citrullinated protein antibody response in rheumatoid arthritis.

Sokolove J, Brennan MJ, Sharpe O, Lahey LJ, Kao AH, Krishnan E, Edmundowicz D, Lepus CM, Wasko MC, Robinson WH.

Arthritis Rheum. 2013 Jul;65(7):1719-24. doi: 10.1002/art.37961.


The effect of opioid therapy on endocrine function.

Brennan MJ.

Am J Med. 2013 Mar;126(3 Suppl 1):S12-8. doi: 10.1016/j.amjmed.2012.12.001. Review.


Buprenorphine transdermal system and quality of life in opioid-experienced patients with chronic low back pain.

Miller K, Yarlas A, Wen W, Dain B, Lynch SY, Brennan MJ, Ripa SR.

Expert Opin Pharmacother. 2013 Feb;14(3):269-77. doi: 10.1517/14656566.2013.767331.


Nonclinical Development of BCG Replacement Vaccine Candidates.

Velmurugan K, Grode L, Chang R, Fitzpatrick M, Laddy D, Hokey D, Derrick S, Morris S, McCown D, Kidd R, Gengenbacher M, Eisele B, Kaufmann SH, Fulkerson J, Brennan MJ.

Vaccines (Basel). 2013 Apr 16;1(2):120-38. doi: 10.3390/vaccines1020120.


Designing an adaptive phase II/III trial to evaluate efficacy, safety and immune correlates of new TB vaccines in young adults and adolescents.

Rustomjee R, McClain B, Brennan MJ, McLeod R, Chetty-Makkan CM, McShane H, Hanekom W, Steel G, Mahomed H, Ginsberg AM, Shea J, Lockhart S, Self S, Churchyard GJ.

Tuberculosis (Edinb). 2013 Mar;93(2):136-42. doi: 10.1016/ Epub 2012 Dec 23.


The clinical implications of cytochrome p450 interactions with opioids and strategies for pain management.

Brennan MJ.

J Pain Symptom Manage. 2012 Dec;44(6 Suppl):S15-22. doi: 10.1016/j.jpainsymman.2012.08.012.


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