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Items: 1 to 50 of 229

1.

Mutation Clearance after Transplantation for Myelodysplastic Syndrome.

Duncavage EJ, Jacoby MA, Chang GS, Miller CA, Edwin N, Shao J, Elliott K, Robinson J, Abel H, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Brendel K, Saba R, Wartman LD, Christopher MJ, Pusic I, Welch JS, Uy GL, Link DC, DiPersio JF, Westervelt P, Ley TJ, Trinkaus K, Graubert TA, Walter MJ.

N Engl J Med. 2018 Sep 13;379(11):1028-1041. doi: 10.1056/NEJMoa1804714.

2.

Development and performance of npde for the evaluation of time-to-event models.

Cerou M, Lavielle M, Brendel K, Chenel M, Comets E.

Pharm Res. 2018 Jan 9;35(2):30. doi: 10.1007/s11095-017-2291-3.

PMID:
29368033
3.

Rotational Spectroscopy Probes Water Flipping by Full Fluorination of Benzene.

Evangelisti L, Brendel K, Mäder H, Caminati W, Melandri S.

Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13699-13703. doi: 10.1002/anie.201707155. Epub 2017 Oct 2.

PMID:
28873260
4.

First-in-human phase I study of oral S49076, a unique MET/AXL/FGFR inhibitor, in advanced solid tumours.

Rodon J, Postel-Vinay S, Hollebecque A, Nuciforo P, Azaro A, Cattan V, Marfai L, Sudey I, Brendel K, Delmas A, Malasse S, Soria JC.

Eur J Cancer. 2017 Aug;81:142-150. doi: 10.1016/j.ejca.2017.05.007.

PMID:
28624695
5.

Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling.

Stadler S, Nguyen CH, Schachner H, Milovanovic D, Holzner S, Brenner S, Eichsteininger J, Stadler M, Senfter D, Krenn L, Schmidt WM, Huttary N, Krieger S, Koperek O, Bago-Horvath Z, Brendel KA, Marian B, de Wever O, Mader RM, Giessrigl B, Jäger W, Dolznig H, Krupitza G.

Cell Mol Life Sci. 2017 May;74(10):1907-1921. doi: 10.1007/s00018-016-2441-5. Epub 2016 Dec 24.

6.

Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation.

Ashraf MI, Schwelberger HG, Brendel KA, Feurle J, Andrassy J, Kotsch K, Regele H, Pratschke J, Maier HT, Aigner F.

Am J Transplant. 2016 Mar;16(3):808-20. doi: 10.1111/ajt.13521. Epub 2015 Nov 23.

7.

Model-based approaches for ivabradine development in paediatric population, part I: study preparation assessment.

Peigné S, Bouzom F, Brendel K, Gesson C, Fouliard S, Chenel M.

J Pharmacokinet Pharmacodyn. 2016 Feb;43(1):13-27. doi: 10.1007/s10928-015-9451-z. Epub 2015 Nov 12.

PMID:
26563503
8.

Going gently into that good night: what is the best death?

Brendel K, Payne D.

BMJ. 2015 Jan 23;350:h393. doi: 10.1136/bmj.h393. No abstract available.

PMID:
25616275
9.

Changes in the diagnosis and treatment of patients with low grade lymphoma in Germany: years 2006-2009.

Schmidt C, Fingerle-Rowson G, Boehme A, Brendel K, Fischer R, Gonnermann M, Höhler T, Kegel T, Kellermann L, Nusch A, Pönisch W, Wendtner C, Dreyling M.

Leuk Lymphoma. 2015 Mar;56(3):694-702. doi: 10.3109/10428194.2014.928935. Epub 2014 Aug 19.

PMID:
24937122
10.

Low prevalence of clopidogrel and acetylsalicylic acid resistance in patients with acute myocardial infarction and pantoprazole treatment in everyday practice.

Brendel K, Weigel G, Griesmacher A, Pachinger O, Mair J.

Int J Cardiol. 2013 Sep 20;168(1):589-90. doi: 10.1016/j.ijcard.2013.01.246. Epub 2013 Feb 26. No abstract available.

PMID:
23484738
11.

Optimal sampling times for a drug and its metabolite using SIMCYP(®) simulations as prior information.

Dumont C, Mentré F, Gaynor C, Brendel K, Gesson C, Chenel M.

Clin Pharmacokinet. 2013 Jan;52(1):43-57. doi: 10.1007/s40262-012-0022-9.

12.

Why should prediction discrepancies be renamed standardized visual predictive check?

Comets E, Brendel K, Mentré F.

J Clin Pharmacol. 2012 Aug;52(8):1284-5; author reply 1286-7. doi: 10.1177/0091270011412963. Epub 2011 Sep 10. No abstract available.

13.

Evaluation of different tests based on observations for external model evaluation of population analyses.

Brendel K, Comets E, Laffont C, Mentré F.

J Pharmacokinet Pharmacodyn. 2010 Feb;37(1):49-65. doi: 10.1007/s10928-009-9143-7. Epub 2009 Dec 23.

14.

Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: the npde add-on package for R.

Comets E, Brendel K, Mentré F.

Comput Methods Programs Biomed. 2008 May;90(2):154-66. doi: 10.1016/j.cmpb.2007.12.002. Epub 2008 Jan 22.

PMID:
18215437
15.

Overview of model-building strategies in population PK/PD analyses: 2002-2004 literature survey.

Dartois C, Brendel K, Comets E, Laffont CM, Laveille C, Tranchand B, Mentré F, Lemenuel-Diot A, Girard P.

Br J Clin Pharmacol. 2007 Nov;64(5):603-12. Epub 2007 Aug 15. Review.

16.

Are population pharmacokinetic and/or pharmacodynamic models adequately evaluated? A survey of the literature from 2002 to 2004.

Brendel K, Dartois C, Comets E, Lemenuel-Diot A, Laveille C, Tranchand B, Girard P, Laffont CM, Mentré F.

Clin Pharmacokinet. 2007;46(3):221-34. Review.

17.

Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide.

Brendel K, Comets E, Laffont C, Laveille C, Mentré F.

Pharm Res. 2006 Sep;23(9):2036-49. Epub 2006 Aug 12.

18.

Synthesis and evaluation of long-acting D-penicillamine derivatives.

Chvapil M, Kielar F, Liska F, Silhankova A, Brendel K.

Connect Tissue Res. 2005;46(4-5):242-50.

PMID:
16546828
19.

Absence of association between MDR1 genetic polymorphisms, indinavir pharmacokinetics and response to highly active antiretroviral therapy.

Verstuyft C, Marcellin F, Morand-Joubert L, Launay O, Brendel K, Mentré F, Peytavin G, Gérard L, Becquemont L, Aboulker JP; ANRS081 Study Group.

AIDS. 2005 Dec 2;19(18):2127-31.

PMID:
16284462
20.

Population pharmacokinetic analysis of indinavir in HIV-infected patient treated with a stable antiretroviral therapy.

Brendel K, Legrand M, Taburet AM, Baron G, Goujard C, Mentré F; Cophar 1-ANRS 102 Trial Group.

Fundam Clin Pharmacol. 2005 Jun;19(3):373-83.

PMID:
15910662
21.

Nucleation times in the two-dimensional Ising model.

Brendel K, Barkema GT, van Beijeren H.

Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Mar;71(3 Pt 1):031601. Epub 2005 Mar 11.

PMID:
15903437
22.

Precision-cut tissue slices from transgenic mice as an in vitro toxicology system.

Catania JM, Parrish AR, Kirkpatrick DS, Chitkara M, Bowden GT, Henderson CJ, Wolf CR, Clark AJ, Brendel K, Fisher RL, Gandolfi AJ.

Toxicol In Vitro. 2003 Apr;17(2):201-5.

PMID:
12650674
23.

Magnetization reversal times in the two-dimensional Ising model.

Brendel K, Barkema GT, van Beijeren H.

Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Feb;67(2 Pt 2):026119. Epub 2003 Feb 26.

PMID:
12636760
24.

Cold and cryopreservation of monkey liver slices.

Fisher RL, Hasal SJ, Lipscomb JC, Gandolfi AJ, Brendel K.

Toxicol Mech Methods. 2002;12(2):119-33. doi: 10.1080/10517230290075350.

PMID:
20021197
25.

Human liver quality is a dominant factor in the outcome of in vitro studies.

Fisher RL, Gandolfi AJ, Brendel K.

Cell Biol Toxicol. 2001;17(3):179-89.

PMID:
11693579
26.
27.

Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines.

Lim JT, Piazza GA, Han EK, Delohery TM, Li H, Finn TS, Buttyan R, Yamamoto H, Sperl GJ, Brendel K, Gross PH, Pamukcu R, Weinstein IB.

Biochem Pharmacol. 1999 Oct 1;58(7):1097-107.

PMID:
10484067
28.

Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver and kidney slices.

Parrish AR, Fisher R, Bral CM, Burghardt RC, Gandolfi AJ, Brendel K, Ramos KS.

Toxicol Appl Pharmacol. 1998 Oct;152(2):302-8.

PMID:
9852999
29.

Effects of taurine in precision-cut liver slices exposed to the pyrrolizidine alkaloid retrorsine.

Hasal SJ, Sun Y, Yan CC, Brendel K, Huxtable RJ.

Adv Exp Med Biol. 1998;442:79-83. No abstract available.

PMID:
9635017
30.

Pyrrolizidine alkaloid-induced depletion of taurine from rat liver in vivo and in vitro.

Sun Y, Hasal SJ, Yan CC, Brendel K, Huxtable RJ.

Adv Exp Med Biol. 1998;442:71-7. No abstract available.

PMID:
9635016
31.

Sampling designs for xerophthalmia prevalence surveys.

Katz J, Yoon SS, Brendel K, West KP Jr.

Int J Epidemiol. 1997 Oct;26(5):1041-8.

PMID:
9363526
32.

Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels.

Piazza GA, Alberts DS, Hixson LJ, Paranka NS, Li H, Finn T, Bogert C, Guillen JM, Brendel K, Gross PH, Sperl G, Ritchie J, Burt RW, Ellsworth L, Ahnen DJ, Pamukcu R.

Cancer Res. 1997 Jul 15;57(14):2909-15.

33.

Human and rat lung biotransformation of cyclosporin A and its derivatives using slices and bronchial epithelial cells.

Vickers AE, Jimenez RM, Spaans MC, Pflimlin V, Fisher RL, Brendel K.

Drug Metab Dispos. 1997 Jul;25(7):873-80.

PMID:
9224782
34.

Efficiency of EPI cluster sampling for assessing diarrhoea and dysentery prevalence.

Yoon SS, Katz J, Brendel K, West KP Jr.

Bull World Health Organ. 1997;75(5):417-26.

35.

Liver slices as a model in drug metabolism.

Ferrero JL, Brendel K.

Adv Pharmacol. 1997;43:131-69. Review. No abstract available.

PMID:
9342175
36.

Increased resistance to acetaminophen-induced hepatotoxicity in retrovirus-infected mice.

Chow HH, Tang Y, Li P, Fisher RL, Brendel K, Watson RR.

Biopharm Drug Dispos. 1996 Nov;17(8):661-74.

PMID:
8950046
37.

Protein arylation precedes acetaminophen toxicity in a dynamic organ slice culture of mouse kidney.

Hoivik DJ, Fisher RL, Brendel K, Gandolfi AJ, Khairallah EA, Cohen SD.

Fundam Appl Toxicol. 1996 Nov;34(1):99-104.

PMID:
8937897
38.

Vitamin A potentiation of vinylidene chloride hepatotoxicity in rats and precision-cut rat liver slices.

Wueweera JB, Gandolfi AJ, Badger DA, Sipes IG, Brendel K.

Fundam Appl Toxicol. 1996 Nov;34(1):73-83.

PMID:
8937894
39.

Biotransformation of a somatostatin analogue in precision-cut liver and kidney slices from rat, dog and man.

Connors MS, Larrauri A, Dannecker R, Nufer R, Brendel K, Vickers AE.

Xenobiotica. 1996 Feb;26(2):133-41.

PMID:
8867998
40.

Cold- and cryopreservation of dog liver and kidney slices.

Fisher RL, Hasal SJ, Sanuik JT, Hasal KS, Gandolfi AJ, Brendel K.

Cryobiology. 1996 Feb;33(1):163-71.

PMID:
8812095
41.

Biotransformation of the antiemetic 5-HT3 antagonist tropisetron in liver and kidney slices of human, rat and dog with a comparison to in vivo.

Vickers AE, Fischer V, Connors MS, Biggi WA, Heitz F, Baldeck JP, Brendel K.

Eur J Drug Metab Pharmacokinet. 1996 Jan-Mar;21(1):43-50.

PMID:
8839677
42.

Use of precision-cut liver slices as an in vitro tool for evaluating liver function.

Gandolfi AJ, Wijeweera J, Brendel K.

Toxicol Pathol. 1996 Jan-Feb;24(1):58-61. Review.

PMID:
8839281
43.

Determination of aflatoxin B1 biotransformation and binding to hepatic macromolecules in human precision liver slices.

Heinonen JT, Fisher R, Brendel K, Eaton DL.

Toxicol Appl Pharmacol. 1996 Jan;136(1):1-7.

PMID:
8560461
44.

Use of tissue slices in chemical mixture toxicology and interspecies investigations.

Gandolfi AJ, Brendel K, Fisher RL, Michaud JP.

Toxicology. 1995 Dec 28;105(2-3):285-90.

PMID:
8571365
45.

Sodium arsenite and heat shock induce stress proteins in precision-cut rat liver slices.

Wijeweera JB, Thomas CM, Gandolfi AJ, Brendel K.

Toxicology. 1995 Dec 15;104(1-3):35-45.

PMID:
8560500
46.

Inhibition of mammary carcinogenesis in rats by sulfone metabolite of sulindac.

Thompson HJ, Briggs S, Paranka NS, Piazza GA, Brendel K, Gross PH, Sperl GJ, Pamukcu R, Ahnen DJ.

J Natl Cancer Inst. 1995 Aug 16;87(16):1259-60. No abstract available.

PMID:
7563174
47.

Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis.

Piazza GA, Rahm AL, Krutzsch M, Sperl G, Paranka NS, Gross PH, Brendel K, Burt RW, Alberts DS, Pamukcu R, et al.

Cancer Res. 1995 Jul 15;55(14):3110-6.

48.

Comparative metabolism and toxicity of dichlorobenzenes in Sprague-Dawley, Fischer-344 and human liver slices.

Fisher RL, Hasal SJ, Sipes IG, Gandolfi AJ, Brendel K.

Hum Exp Toxicol. 1995 May;14(5):414-21.

PMID:
7612303
49.

Biotransformation of sevoflurane by rat neonate liver slices.

Payne AK, Morgan SE, Gandolfi AJ, Brendel K.

Drug Metab Dispos. 1995 Apr;23(4):497-500.

PMID:
7600918
50.

Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism.

Vickers AE, Fisher RL, Brendel K, Guertler J, Dannecker R, Keller B, Fischer V.

Drug Metab Dispos. 1995 Mar;23(3):327-33.

PMID:
7628297

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