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Items: 1 to 50 of 111

1.

Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia.

Xu S, Luk K, Yao Q, Shen AH, Zeng J, Wu Y, Luo HY, Brendel C, Pinello L, Chui DHK, Wolfe SA, Bauer DE.

Blood. 2019 Jan 31. pii: blood-2019-01-895094. doi: 10.1182/blood-2019-01-895094. [Epub ahead of print]

PMID:
30704988
2.

Outcome of non-mold effective anti-fungal prophylaxis in patients at high-risk for invasive fungal infections after allogenic stem cell transplantation.

Christen D, Sohlbach K, Metzelder SK, Wollmer E, Hoeffkes HG, Naumann R, Burchardt A, Rummel M, Trenker C, Dohse M, Mack E, Klameth A, Mann C, Kostrewa P, Brendel C, Wündisch T, Neubauer A, Wilhelm C, Burchert A.

Leuk Lymphoma. 2019 Jan 15:1-6. doi: 10.1080/10428194.2018.1553303. [Epub ahead of print]

PMID:
30644334
3.

Catchment-scale Phosphorus Export through Surface and Drainage Pathways.

Brendel CE, Soupir ML, Long LAM, Helmers MJ, Ikenberry CD, Kaleita AL.

J Environ Qual. 2019 Jan;48(1):117-126. doi: 10.2134/jeq2018.07.0265.

PMID:
30640359
4.

DROSHA Knockout Leads to Enhancement of Viral Titers for Vectors Encoding miRNA-Adapted shRNAs.

Park HH, Triboulet R, Bentler M, Guda S, Du P, Xu H, Gregory RI, Brendel C, Williams DA.

Mol Ther Nucleic Acids. 2018 Sep 7;12:591-599. doi: 10.1016/j.omtn.2018.07.002. Epub 2018 Jul 9.

5.

Comprehensive genetic diagnosis of acute myeloid leukemia by next-generation sequencing.

Mack EKM, Marquardt A, Langer D, Ross P, Ultsch A, Kiehl MG, Mack HID, Haferlach T, Neubauer A, Brendel C.

Haematologica. 2019 Feb;104(2):277-287. doi: 10.3324/haematol.2018.194258. Epub 2018 Sep 6.

6.

Development, Function, and Clinical Significance of Plasmacytoid Dendritic Cells in Chronic Myeloid Leukemia.

Inselmann S, Wang Y, Saussele S, Fritz L, Schütz C, Huber M, Liebler S, Ernst T, Cai D, Botschek S, Brendel C, Calogero RA, Pavlinic D, Benes V, Liu ET, Neubauer A, Hochhaus A, Burchert A.

Cancer Res. 2018 Nov 1;78(21):6223-6234. doi: 10.1158/0008-5472.CAN-18-1477. Epub 2018 Aug 30.

PMID:
30166420
7.

Compatibility of RUNX1/ETO fusion protein modules driving CD34+ human progenitor cell expansion.

Chen-Wichmann L, Shvartsman M, Preiss C, Hockings C, Windisch R, Redondo Monte E, Leubolt G, Spiekermann K, Lausen J, Brendel C, Grez M, Greif PA, Wichmann C.

Oncogene. 2019 Jan;38(2):261-272. doi: 10.1038/s41388-018-0441-7. Epub 2018 Aug 9.

PMID:
30093631
8.

High β-1,4-Galactosyltransferase-I expression in peripheral T-lymphocytes is associated with a low risk of relapse in germ-cell cancer patients receiving high-dose chemotherapy with autologous stem cell reinfusion.

Nilius V, Killer MC, Timmesfeld N, Schmitt M, Moll R, Lorch A, Beyer J, Mack E, Lohoff M, Burchert A, Neubauer A, Brendel C.

Oncoimmunology. 2018 Feb 16;7(5):e1423169. doi: 10.1080/2162402X.2017.1423169. eCollection 2018.

9.

Non-Clinical Efficacy and Safety Studies on G1XCGD, a Lentiviral Vector for Ex Vivo Gene Therapy of X-Linked Chronic Granulomatous Disease.

Brendel C, Rothe M, Santilli G, Charrier S, Stein S, Kunkel H, Abriss D, Müller-Kuller U, Gaspar B, Modlich U, Galy A, Schambach A, Thrasher AJ, Grez M.

Hum Gene Ther Clin Dev. 2018 Jun;29(2):69-79. doi: 10.1089/humc.2017.245. Epub 2018 Apr 17.

PMID:
29664709
10.

Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML.

Schütz C, Inselmann S, Saussele S, Dietz CT, Müller MC, Eigendorff E, Brendel CA, Metzelder SK, Brümmendorf TH, Waller C, Dengler J, Goebeler ME, Herbst R, Freunek G, Hanzel S, Illmer T, Wang Y, Lange T, Finkernagel F, Hehlmann R, Huber M, Neubauer A, Hochhaus A, Guilhot J, Mahon FX, Pfirrmann M, Burchert A.

Leukemia. 2018 Apr;32(4):1054. doi: 10.1038/leu.2017.348. Epub 2018 Jan 30.

PMID:
29381150
11.

Maintenance of cellular respiration indicates drug resistance in acute myeloid leukemia.

Henkenius K, Greene BH, Barckhausen C, Hartmann R, Märken M, Kaiser T, Rehberger M, Metzelder SK, Parak WJ, Neubauer A, Brendel C, Mack E.

Leuk Res. 2017 Nov;62:56-63. doi: 10.1016/j.leukres.2017.09.021. Epub 2017 Sep 28.

PMID:
28985623
12.

Curative approaches for sickle cell disease: A review of allogeneic and autologous strategies.

Bauer DE, Brendel C, Fitzhugh CD.

Blood Cells Mol Dis. 2017 Sep;67:155-168. doi: 10.1016/j.bcmd.2017.08.014. Epub 2017 Sep 1. Review.

PMID:
28893518
13.

Immunosuppressive capacity of mesenchymal stem cells correlates with metabolic activity and can be enhanced by valproic acid.

Killer MC, Nold P, Henkenius K, Fritz L, Riedlinger T, Barckhausen C, Frech M, Hackstein H, Neubauer A, Brendel C.

Stem Cell Res Ther. 2017 Apr 26;8(1):100. doi: 10.1186/s13287-017-0553-y.

14.

Pseudomagnetic fields for sound at the nanoscale.

Brendel C, Peano V, Painter OJ, Marquardt F.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3390-E3395. doi: 10.1073/pnas.1615503114. Epub 2017 Apr 11.

15.

Diverse C-Terminal Sequences Involved in Flavobacterium johnsoniae Protein Secretion.

Kulkarni SS, Zhu Y, Brendel CJ, McBride MJ.

J Bacteriol. 2017 May 25;199(12). pii: e00884-16. doi: 10.1128/JB.00884-16. Print 2017 Jun 15.

16.

Optimizing conditions for labeling of mesenchymal stromal cells (MSCs) with gold nanoparticles: a prerequisite for in vivo tracking of MSCs.

Nold P, Hartmann R, Feliu N, Kantner K, Gamal M, Pelaz B, Hühn J, Sun X, Jungebluth P, Del Pino P, Hackstein H, Macchiarini P, Parak WJ, Brendel C.

J Nanobiotechnology. 2017 Mar 29;15(1):24. doi: 10.1186/s12951-017-0258-5.

17.

Diverse Applications of Nanomedicine.

Pelaz B, Alexiou C, Alvarez-Puebla RA, Alves F, Andrews AM, Ashraf S, Balogh LP, Ballerini L, Bestetti A, Brendel C, Bosi S, Carril M, Chan WC, Chen C, Chen X, Chen X, Cheng Z, Cui D, Du J, Dullin C, Escudero A, Feliu N, Gao M, George M, Gogotsi Y, Grünweller A, Gu Z, Halas NJ, Hampp N, Hartmann RK, Hersam MC, Hunziker P, Jian J, Jiang X, Jungebluth P, Kadhiresan P, Kataoka K, Khademhosseini A, Kopeček J, Kotov NA, Krug HF, Lee DS, Lehr CM, Leong KW, Liang XJ, Ling Lim M, Liz-Marzán LM, Ma X, Macchiarini P, Meng H, Möhwald H, Mulvaney P, Nel AE, Nie S, Nordlander P, Okano T, Oliveira J, Park TH, Penner RM, Prato M, Puntes V, Rotello VM, Samarakoon A, Schaak RE, Shen Y, Sjöqvist S, Skirtach AG, Soliman MG, Stevens MM, Sung HW, Tang BZ, Tietze R, Udugama BN, VanEpps JS, Weil T, Weiss PS, Willner I, Wu Y, Yang L, Yue Z, Zhang Q, Zhang Q, Zhang XE, Zhao Y, Zhou X, Parak WJ.

ACS Nano. 2017 Mar 28;11(3):2313-2381. doi: 10.1021/acsnano.6b06040. Epub 2017 Mar 14.

18.

Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML.

Schütz C, Inselmann S, Saussele S, Dietz CT, Mu Ller MC, Eigendorff E, Brendel CA, Metzelder SK, Bru Mmendorf TH, Waller C, Dengler J, Goebeler ME, Herbst R, Freunek G, Hanzel S, Illmer T, Wang Y, Lange T, Finkernagel F, Hehlmann R, Huber M, Neubauer A, Hochhaus A, Guilhot J, Xavier Mahon F, Pfirrmann M, Burchert A.

Leukemia. 2017 Apr;31(4):829-836. doi: 10.1038/leu.2017.9. Epub 2017 Jan 11. Erratum in: Leukemia. 2018 Jan 30;:.

PMID:
28074067
19.

Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.

Brendel C, Guda S, Renella R, Bauer DE, Canver MC, Kim YJ, Heeney MM, Klatt D, Fogel J, Milsom MD, Orkin SH, Gregory RI, Williams DA.

J Clin Invest. 2016 Oct 3;126(10):3868-3878. doi: 10.1172/JCI87885. Epub 2016 Sep 6.

20.

RhoH participates in a multi-protein complex with the zinc finger protein kaiso that regulates both cytoskeletal structures and chemokine-induced T cells.

Mino A, Troeger A, Brendel C, Cantor A, Harris C, Ciuculescu MF, Williams DA.

Small GTPases. 2018 May 4;9(3):260-273. doi: 10.1080/21541248.2016.1220780. Epub 2016 Aug 31.

21.

A rational two-step approach to KRAS mutation testing in colorectal cancer using high resolution melting analysis and pyrosequencing.

Mack E, Stabla K, Riera-Knorrenschild J, Moll R, Neubauer A, Brendel C.

BMC Cancer. 2016 Aug 2;16:585. doi: 10.1186/s12885-016-2589-2.

22.

Mathematical modeling of erythrocyte chimerism informs genetic intervention strategies for sickle cell disease.

Altrock PM, Brendel C, Renella R, Orkin SH, Williams DA, Michor F.

Am J Hematol. 2016 Sep;91(9):931-7. doi: 10.1002/ajh.24449. Epub 2016 Jul 14.

23.

Contact-dependent abrogation of bone marrow-derived plasmacytoid dendritic cell differentiation by murine mesenchymal stem cells.

Hackstein H, Tschipakow I, Bein G, Nold P, Brendel C, Baal N.

Biochem Biophys Res Commun. 2016 Jul 15;476(1):15-20. doi: 10.1016/j.bbrc.2016.05.108. Epub 2016 May 24.

PMID:
27233615
24.

Surface Functionalization of Orthopedic Titanium Implants with Bone Sialoprotein.

Baranowski A, Klein A, Ritz U, Ackermann A, Anthonissen J, Kaufmann KB, Brendel C, Götz H, Rommens PM, Hofmann A.

PLoS One. 2016 Apr 25;11(4):e0153978. doi: 10.1371/journal.pone.0153978. eCollection 2016.

25.

A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma.

Gossmann J, Stolte M, Lohoff M, Yu P, Moll R, Finkernagel F, Garn H, Brendel C, Bittner A, Neubauer A, Huynh MQ.

PLoS One. 2016 Mar 11;11(3):e0150411. doi: 10.1371/journal.pone.0150411. eCollection 2016.

26.

Topological phase transitions and chiral inelastic transport induced by the squeezing of light.

Peano V, Houde M, Brendel C, Marquardt F, Clerk AA.

Nat Commun. 2016 Mar 2;7:10779. doi: 10.1038/ncomms10779.

27.

Hyperinflammation in patients with chronic granulomatous disease leads to impairment of hematopoietic stem cell functions.

Weisser M, Demel UM, Stein S, Chen-Wichmann L, Touzot F, Santilli G, Sujer S, Brendel C, Siler U, Cavazzana M, Thrasher AJ, Reichenbach J, Essers MA, Schwäble J, Grez M.

J Allergy Clin Immunol. 2016 Jul;138(1):219-228.e9. doi: 10.1016/j.jaci.2015.11.028. Epub 2016 Feb 4.

PMID:
26853280
28.

Prospectively defined murine mesenchymal stem cells inhibit Klebsiella pneumoniae-induced acute lung injury and improve pneumonia survival.

Hackstein H, Lippitsch A, Krug P, Schevtschenko I, Kranz S, Hecker M, Dietert K, Gruber AD, Bein G, Brendel C, Baal N.

Respir Res. 2015 Oct 6;16:123. doi: 10.1186/s12931-015-0288-1.

29.

Group therapy task training versus individual task training during inpatient stroke rehabilitation: a randomised controlled trial.

Renner CIe, Outermans J, Ludwig R, Brendel C, Kwakkel G, Hummelsheim H.

Clin Rehabil. 2016 Jul;30(7):637-48. doi: 10.1177/0269215515600206. Epub 2015 Aug 27.

PMID:
26316552
30.

Pattern phase diagram for two-dimensional arrays of coupled limit-cycle oscillators.

Lauter R, Brendel C, Habraken SJ, Marquardt F.

Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Jul;92(1):012902. Epub 2015 Jul 6.

PMID:
26274242
31.

miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction.

Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, Williams DA.

Mol Ther. 2015 Sep;23(9):1465-74. doi: 10.1038/mt.2015.113. Epub 2015 Jun 17.

32.

NFATc1 as a therapeutic target in FLT3-ITD-positive AML.

Metzelder SK, Michel C, von Bonin M, Rehberger M, Hessmann E, Inselmann S, Solovey M, Wang Y, Sohlbach K, Brendel C, Stiewe T, Charles J, Ten Haaf A, Ellenrieder V, Neubauer A, Gattenlöhner S, Bornhäuser M, Burchert A.

Leukemia. 2015 Jul;29(7):1470-7. doi: 10.1038/leu.2015.95. Epub 2015 Apr 14.

PMID:
25976987
33.

Oncogenic NRAS Primes Primary Acute Myeloid Leukemia Cells for Differentiation.

Brendel C, Teichler S, Millahn A, Stiewe T, Krause M, Stabla K, Ross P, Huynh M, Illmer T, Mernberger M, Barckhausen C, Neubauer A.

PLoS One. 2015 Apr 22;10(4):e0123181. doi: 10.1371/journal.pone.0123181. eCollection 2015.

34.

Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl+ K562 and Jak2(V617F)+ HEL Leukemia Cells.

Weber A, Borghouts C, Brendel C, Moriggl R, Delis N, Brill B, Vafaizadeh V, Groner B.

Cancers (Basel). 2015 Mar 19;7(1):503-37. doi: 10.3390/cancers7010503.

35.

Sorafenib induces paradoxical phosphorylation of the extracellular signal-regulated kinase pathway in acute myeloid leukemia cells lacking FLT3-ITD mutation.

Fouladi F, Jehn LB, Metzelder SK, Hub F, Henkenius K, Burchert A, Brendel C, Stiewe T, Neubauer A.

Leuk Lymphoma. 2015;56(9):2690-8. doi: 10.3109/10428194.2014.1003055. Epub 2015 Mar 3.

36.

A rare ancestral HLA-DRB1(∗)15:01̃DQB1(∗)02:01 haplotype and its reversion in the same Western European family.

Binder TM, Kelsch R, Wikner JM, Aly L, Brendel C, Alster I, Kühnl P, Finckh U, Eiermann TH.

Hum Immunol. 2015 Mar;76(2-3):124-8. doi: 10.1016/j.humimm.2015.01.016. Epub 2015 Jan 27.

PMID:
25636575
37.

A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.

Müller-Kuller U, Ackermann M, Kolodziej S, Brendel C, Fritsch J, Lachmann N, Kunkel H, Lausen J, Schambach A, Moritz T, Grez M.

Nucleic Acids Res. 2015 Feb 18;43(3):1577-92. doi: 10.1093/nar/gkv019. Epub 2015 Jan 20.

38.

Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity.

Singh SK, Chen NM, Hessmann E, Siveke J, Lahmann M, Singh G, Voelker N, Vogt S, Esposito I, Schmidt A, Brendel C, Stiewe T, Gaedcke J, Mernberger M, Crawford HC, Bamlet WR, Zhang JS, Li XK, Smyrk TC, Billadeau DD, Hebrok M, Neesse A, Koenig A, Ellenrieder V.

EMBO J. 2015 Feb 12;34(4):517-30. doi: 10.15252/embj.201489574. Epub 2015 Jan 13.

39.

Characterization of the MeCP2R168X knockin mouse model for Rett syndrome.

Wegener E, Brendel C, Fischer A, Hülsmann S, Gärtner J, Huppke P.

PLoS One. 2014 Dec 26;9(12):e115444. doi: 10.1371/journal.pone.0115444. eCollection 2014.

40.

CD105 is a surface marker for receptor-targeted gene transfer into human long-term repopulating hematopoietic stem cells.

Kays SK, Kaufmann KB, Abel T, Brendel C, Bonig H, Grez M, Buchholz CJ, Kneissl S.

Stem Cells Dev. 2015 Mar 15;24(6):714-23. doi: 10.1089/scd.2014.0455. Epub 2015 Jan 20.

41.

Immunosuppressive capabilities of mesenchymal stromal cells are maintained under hypoxic growth conditions and after gamma irradiation.

Nold P, Hackstein H, Riedlinger T, Kasper C, Neumann A, Mernberger M, Fölsch C, Schmitt J, Fuchs-Winkelmann S, Barckhausen C, Killer M, Neubauer A, Brendel C.

Cytotherapy. 2015 Feb;17(2):152-62. doi: 10.1016/j.jcyt.2014.10.004. Epub 2014 Nov 21.

PMID:
25453724
42.

The inverse agonist DG172 triggers a PPARβ/δ-independent myeloid lineage shift and promotes GM-CSF/IL-4-induced dendritic cell differentiation.

Lieber S, Scheer F, Finkernagel F, Meissner W, Giehl G, Brendel C, Diederich WE, Müller-Brüsselbach S, Müller R.

Mol Pharmacol. 2015 Feb;87(2):162-73. doi: 10.1124/mol.114.094672. Epub 2014 Nov 14.

PMID:
25398837
43.

Selective inhibition of tumor growth by clonal NK cells expressing an ErbB2/HER2-specific chimeric antigen receptor.

Schönfeld K, Sahm C, Zhang C, Naundorf S, Brendel C, Odendahl M, Nowakowska P, Bönig H, Köhl U, Kloess S, Köhler S, Holtgreve-Grez H, Jauch A, Schmidt M, Schubert R, Kühlcke K, Seifried E, Klingemann HG, Rieger MA, Tonn T, Grez M, Wels WS.

Mol Ther. 2015 Feb;23(2):330-8. doi: 10.1038/mt.2014.219. Epub 2014 Nov 6.

44.

CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells.

Brendel C, Goebel B, Daniela A, Brugman M, Kneissl S, Schwäble J, Kaufmann KB, Müller-Kuller U, Kunkel H, Chen-Wichmann L, Abel T, Serve H, Bystrykh L, Buchholz CJ, Grez M.

Mol Ther. 2015 Jan;23(1):63-70. doi: 10.1038/mt.2014.173. Epub 2014 Sep 5. Erratum in: Mol Ther. 2015 Apr;23(4):790.

45.

Unexpected help: mTOR meets lentiviral vectors.

Brendel C, Williams DA.

Blood. 2014 Aug 7;124(6):832-3. doi: 10.1182/blood-2014-06-582411. No abstract available.

46.

Retroviral transduction of murine and human hematopoietic progenitors and stem cells.

Ciuculescu MF, Brendel C, Harris CE, Williams DA.

Methods Mol Biol. 2014;1185:287-309. doi: 10.1007/978-1-4939-1133-2_20.

PMID:
25062637
47.

Reduced fibroblast adhesion and proliferation on plasma-modified titanium surfaces.

Kuhn S, Kroth J, Ritz U, Hofmann A, Brendel C, Müller LP, Förch R, Rommens PM.

J Mater Sci Mater Med. 2014 Nov;25(11):2549-60. doi: 10.1007/s10856-014-5278-1. Epub 2014 Jul 24.

48.

A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels.

Tonigold M, Rossmann A, Meinold M, Bette M, Märken M, Henkenius K, Bretz AC, Giel G, Cai C, Rodepeter FR, Beneš V, Grénman R, Carey TE, Lage H, Stiewe T, Neubauer A, Werner JA, Brendel C, Mandic R.

J Cancer Res Clin Oncol. 2014 Oct;140(10):1689-704. doi: 10.1007/s00432-014-1727-y. Epub 2014 Jun 10.

PMID:
24913304
49.

Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors.

Wichmann C, Quagliano-Lo Coco I, Yildiz Ö, Chen-Wichmann L, Weber H, Syzonenko T, Döring C, Brendel C, Ponnusamy K, Kinner A, Brandts C, Henschler R, Grez M.

Leukemia. 2015 Feb;29(2):279-89. doi: 10.1038/leu.2014.179. Epub 2014 Jun 4.

50.

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