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Items: 42

1.

Potassium restriction boosts vacuolar acidity and extends lifespan in yeast.

Sasikumar AN, Killilea DW, Kennedy BK, Brem RB.

Exp Gerontol. 2019 Jun;120:101-106. doi: 10.1016/j.exger.2019.02.001. Epub 2019 Feb 8.

PMID:
30742903
2.

Transposon insertional mutagenesis in Saccharomyces uvarum reveals trans-acting effects influencing species-dependent essential genes.

Sanchez MR, Payen C, Cheong F, Hovde BT, Bissonnette S, Arkin AP, Skerker JM, Brem RB, Caudy AA, Dunham MJ.

Genome Res. 2019 Mar;29(3):396-406. doi: 10.1101/gr.232330.117. Epub 2019 Jan 11.

PMID:
30635343
3.

Genetic dissection of interspecific differences in yeast thermotolerance.

Weiss CV, Roop JI, Hackley RK, Chuong JN, Grigoriev IV, Arkin AP, Skerker JM, Brem RB.

Nat Genet. 2018 Nov;50(11):1501-1504. doi: 10.1038/s41588-018-0243-4. Epub 2018 Oct 8.

4.

S1PR3 Mediates Itch and Pain via Distinct TRP Channel-Dependent Pathways.

Hill RZ, Morita T, Brem RB, Bautista DM.

J Neurosci. 2018 Sep 5;38(36):7833-7843. doi: 10.1523/JNEUROSCI.1266-18.2018. Epub 2018 Aug 6.

5.

The signaling lipid sphingosine 1-phosphate regulates mechanical pain.

Hill RZ, Hoffman BU, Morita T, Campos SM, Lumpkin EA, Brem RB, Bautista DM.

Elife. 2018 Mar 21;7. pii: e33285. doi: 10.7554/eLife.33285.

6.

Functional genomics of lipid metabolism in the oleaginous yeast Rhodosporidium toruloides.

Coradetti ST, Pinel D, Geiselman GM, Ito M, Mondo SJ, Reilly MC, Cheng YF, Bauer S, Grigoriev IV, Gladden JM, Simmons BA, Brem RB, Arkin AP, Skerker JM.

Elife. 2018 Mar 9;7. pii: e32110. doi: 10.7554/eLife.32110.

7.

Predicting Responses to Contemporary Environmental Change Using Evolutionary Response Architectures.

Bay RA, Rose N, Barrett R, Bernatchez L, Ghalambor CK, Lasky JR, Brem RB, Palumbi SR, Ralph P.

Am Nat. 2017 May;189(5):463-473. doi: 10.1086/691233. Epub 2017 Mar 17. Review.

PMID:
28410032
8.

Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila.

Nelson CS, Beck JN, Wilson KA, Pilcher ER, Kapahi P, Brem RB.

BMC Genomics. 2016 Nov 4;17(1):867.

9.

Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1.

Mark KA, Dumas KJ, Bhaumik D, Schilling B, Davis S, Oron TR, Sorensen DJ, Lucanic M, Brem RB, Melov S, Ramanathan A, Gibson BW, Lithgow GJ.

Cell Rep. 2016 Oct 25;17(5):1227-1237. doi: 10.1016/j.celrep.2016.09.086.

10.

The Role of Transcription Factors at Antisense-Expressing Gene Pairs in Yeast.

Mostovoy Y, Thiemicke A, Hsu TY, Brem RB.

Genome Biol Evol. 2016 Jun 27;8(6):1748-61. doi: 10.1093/gbe/evw104.

11.

Polygenic evolution of a sugar specialization trade-off in yeast.

Roop JI, Chang KC, Brem RB.

Nature. 2016 Feb 18;530(7590):336-9. doi: 10.1038/nature16938. Epub 2016 Feb 10.

12.

Peripheral Circadian Clocks Mediate Dietary Restriction-Dependent Changes in Lifespan and Fat Metabolism in Drosophila.

Katewa SD, Akagi K, Bose N, Rakshit K, Camarella T, Zheng X, Hall D, Davis S, Nelson CS, Brem RB, Ramanathan A, Sehgal A, Giebultowicz JM, Kapahi P.

Cell Metab. 2016 Jan 12;23(1):143-54. doi: 10.1016/j.cmet.2015.10.014. Epub 2015 Nov 25.

13.

A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging.

McCormick MA, Delaney JR, Tsuchiya M, Tsuchiyama S, Shemorry A, Sim S, Chou AC, Ahmed U, Carr D, Murakami CJ, Schleit J, Sutphin GL, Wasko BM, Bennett CF, Wang AM, Olsen B, Beyer RP, Bammler TK, Prunkard D, Johnson SC, Pennypacker JK, An E, Anies A, Castanza AS, Choi E, Dang N, Enerio S, Fletcher M, Fox L, Goswami S, Higgins SA, Holmberg MA, Hu D, Hui J, Jelic M, Jeong KS, Johnston E, Kerr EO, Kim J, Kim D, Kirkland K, Klum S, Kotireddy S, Liao E, Lim M, Lin MS, Lo WC, Lockshon D, Miller HA, Moller RM, Muller B, Oakes J, Pak DN, Peng ZJ, Pham KM, Pollard TG, Pradeep P, Pruett D, Rai D, Robison B, Rodriguez AA, Ros B, Sage M, Singh MK, Smith ED, Snead K, Solanky A, Spector BL, Steffen KK, Tchao BN, Ting MK, Vander Wende H, Wang D, Welton KL, Westman EA, Brem RB, Liu XG, Suh Y, Zhou Z, Kaeberlein M, Kennedy BK.

Cell Metab. 2015 Nov 3;22(5):895-906. doi: 10.1016/j.cmet.2015.09.008. Epub 2015 Oct 8.

14.

HTR7 Mediates Serotonergic Acute and Chronic Itch.

Morita T, McClain SP, Batia LM, Pellegrino M, Wilson SR, Kienzler MA, Lyman K, Olsen AS, Wong JF, Stucky CL, Brem RB, Bautista DM.

Neuron. 2015 Jul 1;87(1):124-38. doi: 10.1016/j.neuron.2015.05.044. Epub 2015 Jun 11.

15.

Expression profiling of the wheat pathogen Zymoseptoria tritici reveals genomic patterns of transcription and host-specific regulatory programs.

Kellner R, Bhattacharyya A, Poppe S, Hsu TY, Brem RB, Stukenbrock EH.

Genome Biol Evol. 2014 May 14;6(6):1353-65. doi: 10.1093/gbe/evu101.

16.

Structural variation among wild and industrial strains of Penicillium chrysogenum.

Wong VL, Ellison CE, Eisen MB, Pachter L, Brem RB.

PLoS One. 2014 May 13;9(5):e96784. doi: 10.1371/journal.pone.0096784. eCollection 2014.

17.

Discovering functions of unannotated genes from a transcriptome survey of wild fungal isolates.

Ellison CE, Kowbel D, Glass NL, Taylor JW, Brem RB.

MBio. 2014 Apr 1;5(2):e01046-13. doi: 10.1128/mBio.01046-13.

18.

Divergence of iron metabolism in wild Malaysian yeast.

Lee HN, Mostovoy Y, Hsu TY, Chang AH, Brem RB.

G3 (Bethesda). 2013 Dec 9;3(12):2187-94. doi: 10.1534/g3.113.008011.

19.

Inferring evolutionary histories of pathway regulation from transcriptional profiling data.

Schraiber JG, Mostovoy Y, Hsu TY, Brem RB.

PLoS Comput Biol. 2013;9(10):e1003255. doi: 10.1371/journal.pcbi.1003255. Epub 2013 Oct 10.

20.

Genome wide association identifies novel loci involved in fungal communication.

Palma-Guerrero J, Hall CR, Kowbel D, Welch J, Taylor JW, Brem RB, Glass NL.

PLoS Genet. 2013;9(8):e1003669. doi: 10.1371/journal.pgen.1003669. Epub 2013 Aug 1.

21.

Rare variants in hypermutable genes underlie common morphology and growth traits in wild Saccharomyces paradoxus.

Roop JI, Brem RB.

Genetics. 2013 Oct;195(2):513-25. doi: 10.1534/genetics.113.155341. Epub 2013 Aug 9.

22.

The star-nosed mole reveals clues to the molecular basis of mammalian touch.

Gerhold KA, Pellegrino M, Tsunozaki M, Morita T, Leitch DB, Tsuruda PR, Brem RB, Catania KC, Bautista DM.

PLoS One. 2013;8(1):e55001. doi: 10.1371/journal.pone.0055001. Epub 2013 Jan 30.

23.

Genealogy-based methods for inference of historical recombination and gene flow and their application in Saccharomyces cerevisiae.

Jenkins PA, Song YS, Brem RB.

PLoS One. 2012;7(11):e46947. doi: 10.1371/journal.pone.0046947. Epub 2012 Nov 30.

24.

Genetics and regulatory impact of alternative polyadenylation in human B-lymphoblastoid cells.

Yoon OK, Hsu TY, Im JH, Brem RB.

PLoS Genet. 2012;8(8):e1002882. doi: 10.1371/journal.pgen.1002882. Epub 2012 Aug 16.

25.

Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation.

Zhu J, Sova P, Xu Q, Dombek KM, Xu EY, Vu H, Tu Z, Brem RB, Bumgarner RE, Schadt EE.

PLoS Biol. 2012;10(4):e1001301. doi: 10.1371/journal.pbio.1001301. Epub 2012 Apr 3.

26.

Negative feedback confers mutational robustness in yeast transcription factor regulation.

Denby CM, Im JH, Yu RC, Pesce CG, Brem RB.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3874-8. doi: 10.1073/pnas.1116360109. Epub 2012 Feb 21.

27.

Evolution of a membrane protein regulon in Saccharomyces.

Martin HC, Roop JI, Schraiber JG, Hsu TY, Brem RB.

Mol Biol Evol. 2012 Jul;29(7):1747-56. doi: 10.1093/molbev/mss017. Epub 2012 Jan 20.

28.

Natural variation in CDC28 underlies morphological phenotypes in an environmental yeast isolate.

Lee HN, Magwene PM, Brem RB.

Genetics. 2011 Jul;188(3):723-30. doi: 10.1534/genetics.111.128819. Epub 2011 Apr 28.

29.

Population genomics and local adaptation in wild isolates of a model microbial eukaryote.

Ellison CE, Hall C, Kowbel D, Welch J, Brem RB, Glass NL, Taylor JW.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2831-6. doi: 10.1073/pnas.1014971108. Epub 2011 Jan 31.

30.

Exploring the genetic basis of variation in gene predictions with a synthetic association study.

Levin TC, Glazer AM, Pachter L, Brem RB, Eisen MB.

PLoS One. 2010 Jul 29;5(7):e11645. doi: 10.1371/journal.pone.0011645.

31.

Noncanonical transcript forms in yeast and their regulation during environmental stress.

Yoon OK, Brem RB.

RNA. 2010 Jun;16(6):1256-67. doi: 10.1261/rna.2038810. Epub 2010 Apr 26.

32.

Polygenic and directional regulatory evolution across pathways in Saccharomyces.

Bullard JH, Mostovoy Y, Dudoit S, Brem RB.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5058-63. doi: 10.1073/pnas.0912959107. Epub 2010 Mar 1.

33.

Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains.

Dimitrov LN, Brem RB, Kruglyak L, Gottschling DE.

Genetics. 2009 Sep;183(1):365-83. doi: 10.1534/genetics.109.104497. Epub 2009 Jul 6.

34.

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks.

Zhu J, Zhang B, Smith EN, Drees B, Brem RB, Kruglyak L, Bumgarner RE, Schadt EE.

Nat Genet. 2008 Jul;40(7):854-61. doi: 10.1038/ng.167. Epub 2008 Jun 15.

35.

Genomewide evolutionary rates in laboratory and wild yeast.

Ronald J, Tang H, Brem RB.

Genetics. 2006 Sep;174(1):541-4. Epub 2006 Jul 2.

36.

Local regulatory variation in Saccharomyces cerevisiae.

Ronald J, Brem RB, Whittle J, Kruglyak L.

PLoS Genet. 2005 Aug;1(2):e25. Epub 2005 Aug 19.

37.

Genetic interactions between polymorphisms that affect gene expression in yeast.

Brem RB, Storey JD, Whittle J, Kruglyak L.

Nature. 2005 Aug 4;436(7051):701-3.

38.

The landscape of genetic complexity across 5,700 gene expression traits in yeast.

Brem RB, Kruglyak L.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1572-7. Epub 2005 Jan 19.

39.

Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors.

Yvert G, Brem RB, Whittle J, Akey JM, Foss E, Smith EN, Mackelprang R, Kruglyak L.

Nat Genet. 2003 Sep;35(1):57-64. Epub 2003 Aug 3.

PMID:
12897782
40.

Genetic dissection of transcriptional regulation in budding yeast.

Brem RB, Yvert G, Clinton R, Kruglyak L.

Science. 2002 Apr 26;296(5568):752-5. Epub 2002 Mar 28.

41.

Immunolocalization of integrins in proliferative retinal membranes.

Robbins SG, Brem RB, Wilson DJ, O'Rourke LM, Robertson JE, Westra I, Planck SR, Rosenbaum JT.

Invest Ophthalmol Vis Sci. 1994 Aug;35(9):3475-85.

PMID:
8056523
42.

Immunolocalization of integrins in the human retina.

Brem RB, Robbins SG, Wilson DJ, O'Rourke LM, Mixon RN, Robertson JE, Planck SR, Rosenbaum JT.

Invest Ophthalmol Vis Sci. 1994 Aug;35(9):3466-74.

PMID:
8056522

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