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Items: 9


An Overview of Two-Component Signal Transduction Systems Implicated in Extra-Intestinal Pathogenic E. coli Infections.

Breland EJ, Eberly AR, Hadjifrangiskou M.

Front Cell Infect Microbiol. 2017 May 9;7:162. doi: 10.3389/fcimb.2017.00162. eCollection 2017. Review.


Identification of a High-Affinity Pyruvate Receptor in Escherichia coli.

Behr S, Kristoficova I, Witting M, Breland EJ, Eberly AR, Sachs C, Schmitt-Kopplin P, Hadjifrangiskou M, Jung K.

Sci Rep. 2017 May 3;7(1):1388. doi: 10.1038/s41598-017-01410-2.


The Histidine Residue of QseC Is Required for Canonical Signaling between QseB and PmrB in Uropathogenic Escherichia coli.

Breland EJ, Zhang EW, Bermudez T, Martinez CR 3rd, Hadjifrangiskou M.

J Bacteriol. 2017 Aug 22;199(18). pii: e00060-17. doi: 10.1128/JB.00060-17. Print 2017 Sep 15.


Signaling by two-component system noncognate partners promotes intrinsic tolerance to polymyxin B in uropathogenic Escherichia coli.

Guckes KR, Breland EJ, Zhang EW, Hanks SC, Gill NK, Algood HM, Schmitz JE, Stratton CW, Hadjifrangiskou M.

Sci Signal. 2017 Jan 10;10(461). pii: eaag1775. doi: 10.1126/scisignal.aag1775.


Purine Biosynthesis Metabolically Constrains Intracellular Survival of Uropathogenic Escherichia coli.

Shaffer CL, Zhang EW, Dudley AG, Dixon BREA, Guckes KR, Breland EJ, Floyd KA, Casella DP, Algood HMS, Clayton DB, Hadjifrangiskou M.

Infect Immun. 2016 Dec 29;85(1). pii: e00471-16. doi: 10.1128/IAI.00471-16. Print 2017 Jan.


Bacillus anthracis GrlAV96A topoisomerase IV, a quinolone resistance mutation that does not affect the water-metal ion bridge.

Aldred KJ, Breland EJ, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N.

Antimicrob Agents Chemother. 2014 Dec;58(12):7182-7. doi: 10.1128/AAC.03734-14. Epub 2014 Sep 22.


Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV.

Aldred KJ, Breland EJ, Vlčková V, Strub MP, Neuman KC, Kerns RJ, Osheroff N.

Biochemistry. 2014 Sep 2;53(34):5558-67. doi: 10.1021/bi500682e. Epub 2014 Aug 21.


Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor.

Guckes KR, Kostakioti M, Breland EJ, Gu AP, Shaffer CL, Martinez CR 3rd, Hultgren SJ, Hadjifrangiskou M.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16592-7. doi: 10.1073/pnas.1315320110. Epub 2013 Sep 23.


A simple method for construction of pir+ Enterobacterial hosts for maintenance of R6K replicon plasmids.

Kvitko BH, Bruckbauer S, Prucha J, McMillan I, Breland EJ, Lehman S, Mladinich K, Choi KH, Karkhoff-Schweizer R, Schweizer HP.

BMC Res Notes. 2012 Mar 20;5:157. doi: 10.1186/1756-0500-5-157.

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