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Items: 1 to 50 of 95

1.

Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood.

Brekke OL, Christiansen D, Kisserli A, Fure H, Dahl JA, Donvito B, Reveil B, Ludviksen JK, Tabary T, Mollnes TE, Cohen JHM.

Mol Immunol. 2019 Jul 25;114:139-148. doi: 10.1016/j.molimm.2019.07.014. [Epub ahead of print]

PMID:
31352230
2.

Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor.

Gravastrand CS, Steinkjer B, Halvorsen B, Landsem A, Skjelland M, Jacobsen EA, Woodruff TM, Lambris JD, Mollnes TE, Brekke OL, Espevik T, Rokstad AMA.

J Immunol. 2019 Aug 15;203(4):853-863. doi: 10.4049/jimmunol.1900503. Epub 2019 Jul 3.

3.

Safe usage of bicalutamide and goserelin in a male patient with acute intermittent porphyria and prostate cancer.

Sofie Lichtwarck Bjugn F, Storjord E, Kristensen RM, Brekke OL.

Scand J Urol. 2019 Apr - Jun;53(2-3):171-173. doi: 10.1080/21681805.2018.1563628. Epub 2019 Feb 4. No abstract available.

PMID:
30714461
4.

Lifestyle factors including diet and biochemical biomarkers in acute intermittent porphyria: Results from a case-control study in northern Norway.

Storjord E, Dahl JA, Landsem A, Ludviksen JK, Karlsen MB, Karlsen BO, Brekke OL.

Mol Genet Metab. 2018 Dec 10. pii: S1096-7192(18)30528-6. doi: 10.1016/j.ymgme.2018.12.006. [Epub ahead of print]

5.

Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4.

Landsem A, Fure H, Krey Ludviksen J, Christiansen D, Lau C, Mathisen M, Bergseth G, Nymo S, Lappegård KT, Woodruff TM, Espevik T, Mollnes TE, Brekke OL.

Clin Exp Immunol. 2019 Apr;196(1):97-110. doi: 10.1111/cei.13240. Epub 2018 Dec 19.

6.

Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism.

Høiland II, Liang RA, Hindberg K, Latysheva N, Brekke OL, Mollnes TE, Hansen JB.

Thromb Res. 2018 Sep;169:50-56. doi: 10.1016/j.thromres.2018.06.019. Epub 2018 Jun 30.

7.

Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) - an ex vivo study with blood from a C5-deficient individual.

Hardersen R, Enebakk T, Christiansen D, Bergseth G, Brekke OL, Mollnes TE, Lappegård KT, Hovland A.

APMIS. 2018 Apr;126(4):342-352. doi: 10.1111/apm.12821.

PMID:
29575196
8.

Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation.

Skjeflo EW, Christiansen D, Fure H, Ludviksen JK, Woodruff TM, Espevik T, Nielsen EW, Brekke OL, Mollnes TE.

J Thromb Haemost. 2018 May;16(5):905-918. doi: 10.1111/jth.13979. Epub 2018 Mar 23.

PMID:
29437288
9.

Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines - Consequences for defining reference values in healthy humans.

Hennø LT, Storjord E, Christiansen D, Bergseth G, Ludviksen JK, Fure H, Barene S, Nielsen EW, Mollnes TE, Brekke OL.

Cytokine. 2017 Sep;97:86-95. doi: 10.1016/j.cyto.2017.05.014. Epub 2017 Jun 6.

PMID:
28595117
10.

Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII.

Gravastrand C, Hamad S, Fure H, Steinkjer B, Ryan L, Oberholzer J, Lambris JD, Lacík I, Mollnes TE, Espevik T, Brekke OL, Rokstad AM.

Acta Biomater. 2017 Aug;58:158-167. doi: 10.1016/j.actbio.2017.05.052. Epub 2017 May 30.

11.

Systemic inflammation in acute intermittent porphyria: a case-control study.

Storjord E, Dahl JA, Landsem A, Fure H, Ludviksen JK, Goldbeck-Wood S, Karlsen BO, Berg KS, Mollnes TE, W Nielsen E, Brekke OL.

Clin Exp Immunol. 2017 Mar;187(3):466-479. doi: 10.1111/cei.12899. Epub 2016 Dec 15.

12.

C1-inhibitor efficiently delays clot development in normal human whole blood and inhibits Escherichia coli-induced coagulation measured by thromboelastometry.

Landsem A, Fure H, Mollnes TE, Nielsen EW, Brekke OL.

Thromb Res. 2016 Jul;143:63-70. doi: 10.1016/j.thromres.2016.04.024. Epub 2016 Apr 28.

PMID:
27197075
13.

Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation.

Ørning P, Hoem KS, Coron AE, Skjåk-Bræk G, Mollnes TE, Brekke OL, Espevik T, Rokstad AM.

J Control Release. 2016 May 10;229:58-69. doi: 10.1016/j.jconrel.2016.03.021. Epub 2016 Mar 16.

PMID:
26993426
14.

Effects on muscle strength, maximal jump height, flexibility and postural sway after soccer and Zumba exercise among female hospital employees: a 9-month randomised controlled trial.

Barene S, Holtermann A, Oseland H, Brekke OL, Krustrup P.

J Sports Sci. 2016 Oct;34(19):1849-58. doi: 10.1080/02640414.2016.1140906. Epub 2016 Feb 5.

PMID:
26849477
15.

Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis.

Skjeflo EW, Sagatun C, Dybwik K, Aam S, Urving SH, Nunn MA, Fure H, Lau C, Brekke OL, Huber-Lang M, Espevik T, Barratt-Due A, Nielsen EW, Mollnes TE.

Crit Care. 2015 Nov 27;19:415. doi: 10.1186/s13054-015-1129-9.

16.

Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response.

Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE.

Genom Data. 2015 May 30;5:176-83. doi: 10.1016/j.gdata.2015.05.019. eCollection 2015 Sep.

17.

The key roles of complement and tissue factor in Escherichia coli-induced coagulation in human whole blood.

Landsem A, Fure H, Christiansen D, Nielsen EW, Østerud B, Mollnes TE, Brekke OL.

Clin Exp Immunol. 2015 Oct;182(1):81-9. doi: 10.1111/cei.12663. Epub 2015 Aug 2.

18.

CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray.

Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE.

PLoS One. 2015 Feb 23;10(2):e0117261. doi: 10.1371/journal.pone.0117261. eCollection 2015.

19.

Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn.

Hallstensen RF, Bergseth G, Foss S, Jæger S, Gedde-Dahl T, Holt J, Christiansen D, Lau C, Brekke OL, Armstrong E, Stefanovic V, Andersen JT, Sandlie I, Mollnes TE.

Immunobiology. 2015 Apr;220(4):452-9. doi: 10.1016/j.imbio.2014.11.003. Epub 2014 Nov 13.

20.

Soccer and Zumba as health-promoting activities among female hospital employees: a 40-weeks cluster randomised intervention study.

Barene S, Krustrup P, Brekke OL, Holtermann A.

J Sports Sci. 2014;32(16):1539-49. doi: 10.1080/02640414.2014.906043. Epub 2014 Apr 10.

PMID:
24720526
21.

Establishing IMMULITE® 2000 cut-off values for serum allergen-specific immunoglobulin and exploring their relationship to exhaled nitric oxide.

Evjenth B, Hansen TE, Brekke OL, Holt J.

Acta Paediatr. 2014 Jul;103(7):759-65. doi: 10.1111/apa.12631. Epub 2014 Mar 31.

22.

Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.

Samstad EO, Niyonzima N, Nymo S, Aune MH, Ryan L, Bakke SS, Lappegård KT, Brekke OL, Lambris JD, Damås JK, Latz E, Mollnes TE, Espevik T.

J Immunol. 2014 Mar 15;192(6):2837-45. doi: 10.4049/jimmunol.1302484. Epub 2014 Feb 19.

23.

Do soccer and Zumba exercise improve fitness and indicators of health among female hospital employees? A 12-week RCT.

Barene S, Krustrup P, Jackman SR, Brekke OL, Holtermann A.

Scand J Med Sci Sports. 2014 Dec;24(6):990-9. doi: 10.1111/sms.12138. Epub 2013 Oct 24.

PMID:
24151956
24.

Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation.

Lau C, Gunnarsen KS, Høydahl LS, Andersen JT, Berntzen G, Pharo A, Lindstad JK, Ludviksen JK, Brekke OL, Barratt-Due A, Nielsen EW, Stokes CR, Espevik T, Sandlie I, Mollnes TE.

J Immunol. 2013 Nov 1;191(9):4769-77. doi: 10.4049/jimmunol.1301653. Epub 2013 Sep 23.

25.

C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood.

Landsem A, Nielsen EW, Fure H, Christiansen D, Ludviksen JK, Lambris JD, Østerud B, Mollnes TE, Brekke OL.

Clin Exp Immunol. 2013 Aug;173(2):217-29. doi: 10.1111/cei.12098.

26.
27.

Effect of broodstock diet on hepatic status and reproductive performance in Atlantic halibut (Hippoglossus hippoglossus L.) females.

Bolla SS, Nicolaisen O, Brekke OL.

Commun Agric Appl Biol Sci. 2013;78(4):45-7. No abstract available.

PMID:
25141619
28.

The induction of cytokines by polycation containing microspheres by a complement dependent mechanism.

Rokstad AM, Brekke OL, Steinkjer B, Ryan L, Kolláriková G, Strand BL, Skjåk-Bræk G, Lambris JD, Lacík I, Mollnes TE, Espevik T.

Biomaterials. 2013 Jan;34(3):621-30. doi: 10.1016/j.biomaterials.2012.10.012. Epub 2012 Oct 24.

PMID:
23103159
29.

Bride and groom in systemic inflammation--the bells ring for complement and Toll in cooperation.

Barratt-Due A, Pischke SE, Brekke OL, Thorgersen EB, Nielsen EW, Espevik T, Huber-Lang M, Mollnes TE.

Immunobiology. 2012 Nov;217(11):1047-56. doi: 10.1016/j.imbio.2012.07.019. Review.

PMID:
22964230
30.

Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood.

Christiansen D, Brekke OL, Stenvik J, Lambris JD, Espevik T, Mollnes TE.

Adv Exp Med Biol. 2012;946:237-51. doi: 10.1007/978-1-4614-0106-3_14. Review.

PMID:
21948372
31.

Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood.

Brekke OL, Hellerud BC, Christiansen D, Fure H, Castellheim A, Nielsen EW, Pharo A, Lindstad JK, Bergseth G, Leslie G, Lambris JD, Brandtzaeg P, Mollnes TE.

Mol Immunol. 2011 Sep;48(15-16):2159-69. doi: 10.1016/j.molimm.2011.07.011. Epub 2011 Aug 11.

32.

Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model.

Rokstad AM, Brekke OL, Steinkjer B, Ryan L, Kolláriková G, Strand BL, Skjåk-Bræk G, Lacík I, Espevik T, Mollnes TE.

Acta Biomater. 2011 Jun;7(6):2566-78. doi: 10.1016/j.actbio.2011.03.011. Epub 2011 Mar 12.

PMID:
21402181
33.

No evidence of impaired endothelial function or altered inflammatory state in patients with familial hypercholesterolemia treated with statins.

Hovland A, Aagnes I, Brekke OL, Flage JH, Lappegård KT.

J Clin Lipidol. 2010 Jul-Aug;4(4):288-92. doi: 10.1016/j.jacl.2010.02.011. Epub 2010 Jun 1.

PMID:
21122661
34.

Selective inhibition of TNF-alpha or IL-1 beta does not affect E. coli-induced inflammation in human whole blood.

Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Brekke OL, Christiansen D, Lambris JD, Mollnes TE.

Mol Immunol. 2010 May;47(9):1774-82. doi: 10.1016/j.molimm.2010.02.026. Epub 2010 Mar 23.

PMID:
20334922
35.

Innate immune responses to danger signals in systemic inflammatory response syndrome and sepsis.

Castellheim A, Brekke OL, Espevik T, Harboe M, Mollnes TE.

Scand J Immunol. 2009 Jun;69(6):479-91. doi: 10.1111/j.1365-3083.2009.02255.x. Review.

36.

Hypothesis: combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response.

Mollnes TE, Christiansen D, Brekke OL, Espevik T.

Adv Exp Med Biol. 2008;632:253-63. Review.

PMID:
19025127
37.

Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood.

Brekke OL, Christiansen D, Fure H, Pharo A, Fung M, Riesenfeld J, Mollnes TE.

Mol Immunol. 2008 Aug;45(14):3804-13. doi: 10.1016/j.molimm.2008.05.017. Epub 2008 Jul 7.

PMID:
18606453
38.

Identification of prostate cancer antigens by automated high-throughput filter immunoscreening.

Alsøe L, Stacy JE, Fosså A, Funderud S, Brekke OH, Gaudernack G.

J Immunol Methods. 2008 Jan 31;330(1-2):12-23. Epub 2007 Nov 20.

PMID:
18045611
39.

Functional phage display of two murine alpha/beta T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance.

Løset GÅ, Lunde E, Bogen B, Brekke OH, Sandlie I.

Protein Eng Des Sel. 2007 Sep;20(9):461-72. Epub 2007 Oct 9.

PMID:
17925331
40.

Incidental findings with Tc-99m MIBI imaging for parathyroid adenoma.

Hustad KV, Staub UH, Bud Mi, Hardersen R, Jaeger S, Brekke OL.

Clin Nucl Med. 2007 Jul;32(7):548-50. No abstract available.

PMID:
17581343
41.

Safe usage of isotretinoin in a woman with latent acute intermittent porphyria.

Storjord E, Brekke OL, Nielsen EW.

Acta Derm Venereol. 2007;87(3):267-8. No abstract available.

42.
43.

Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement.

Nielsen EW, Waage C, Fure H, Brekke OL, Sfyroera G, Lambris JD, Mollnes TE.

Mol Immunol. 2007 Mar;44(8):1819-26. Epub 2006 Nov 13.

PMID:
17101176
44.

Characterization of an FcgammaRI-binding peptide selected by phage display.

Berntzen G, Brekke OH, Mousavi SA, Andersen JT, Michaelsen TE, Berg T, Sandlie I, Lauvrak V.

Protein Eng Des Sel. 2006 Mar;19(3):121-8. Epub 2006 Jan 19.

PMID:
16423844
45.

A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells.

Michaelsen TE, Thommesen JE, Ihle O, Gregers TF, Sandin RH, Brekke OH, Sandlie I.

Eur J Immunol. 2006 Jan;36(1):129-38.

46.

Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repertoire.

Løset GÅ, Løbersli I, Kavlie A, Stacy JE, Borgen T, Kausmally L, Hvattum E, Simonsen B, Hovda MB, Brekke OH.

J Immunol Methods. 2005 Apr;299(1-2):47-62. Epub 2005 Mar 8.

PMID:
15914190
47.

Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production.

Lappegård KT, Riesenfeld J, Brekke OL, Bergseth G, Lambris JD, Mollnes TE.

Ann Thorac Surg. 2005 Mar;79(3):917-23.

PMID:
15734405
48.

Covalent antibody display--an in vitro antibody-DNA library selection system.

Reiersen H, Løbersli I, Løset GÅ, Hvattum E, Simonsen B, Stacy JE, McGregor D, Fitzgerald K, Welschof M, Brekke OH, Marvik OJ.

Nucleic Acids Res. 2005 Jan 14;33(1):e10.

49.

Neutralizing human antibodies to varicella-zoster virus (VZV) derived from a VZV patient recombinant antibody library.

Kausmally L, Waalen K, Løbersli I, Hvattum E, Berntsen G, Michaelsen TE, Brekke OH.

J Gen Virol. 2004 Dec;85(Pt 12):3493-500.

PMID:
15557222
50.

Direct isolation of recombinant human antibodies against group B Neisseria meningitidis from scFv expression libraries.

Stacy JE, Kausmally L, Simonsen B, Nordgard SH, Alsøe L, Michaelsen TE, Brekke OH.

J Immunol Methods. 2003 Dec;283(1-2):247-59.

PMID:
14659916

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