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Items: 1 to 50 of 79

1.

A model for spontaneous B-lineage lymphomas in IgHmu-HOX11 transgenic mice.

Hough MR, Reis MD, Singaraja R, Bryce DM, Kamel-Reid S, Dardick I, Breitman ML, Dubé ID.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13853-8.

2.

The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development.

Tang SJ, Hoodless PA, Lu Z, Breitman ML, McInnes RR, Wrana JL, Buchwald M.

Development. 1998 May;125(10):1877-87.

3.
4.

Regulation of flt-1 expression during mouse embryogenesis suggests a role in the establishment of vascular endothelium.

Fong GH, Klingensmith J, Wood CR, Rossant J, Breitman ML.

Dev Dyn. 1996 Sep;207(1):1-10.

5.

Expression of the bZIP transcription factor gene Nrl in the developing nervous system.

Liu Q, Ji X, Breitman ML, Hitchcock PF, Swaroop A.

Oncogene. 1996 Jan 4;12(1):207-11.

PMID:
8552394
6.

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium.

Fong GH, Rossant J, Gertsenstein M, Breitman ML.

Nature. 1995 Jul 6;376(6535):66-70.

PMID:
7596436
7.

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice.

Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu XF, Breitman ML, Schuh AC.

Nature. 1995 Jul 6;376(6535):62-6.

PMID:
7596435
8.
9.

Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development.

Dumont DJ, Fong GH, Puri MC, Gradwohl G, Alitalo K, Breitman ML.

Dev Dyn. 1995 May;203(1):80-92.

10.

Genetic mapping of two mouse homeobox genes Tlx-1 and Tlx-2 to murine chromosomes 19 and 6.

Wen XY, Tang S, Breitman ML.

Genomics. 1994 Nov 15;24(2):388-90.

PMID:
7698766
11.

Assignment of the endothelial-specific protein receptor tyrosine kinase gene (TEK) to human chromosome 9p21.

Dumont DJ, Anderson L, Breitman ML, Duncan AM.

Genomics. 1994 Sep 15;23(2):512-3. No abstract available.

PMID:
7835909
12.
13.

Two distinct target cells for v-jun mediated wound tumorigenesis.

Shalaby F, Schuh AC, Breitman ML.

Oncogene. 1994 Sep;9(9):2579-88.

PMID:
8058321
14.

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.

Dumont DJ, Gradwohl G, Fong GH, Puri MC, Gertsenstein M, Auerbach A, Breitman ML.

Genes Dev. 1994 Aug 15;8(16):1897-909.

15.

Cone cells fail to develop normally in transgenic mice showing ablation of rod photoreceptor cells.

Usukura J, Khoo W, Abe T, Breitman ML, Shinohara T.

Cell Tissue Res. 1994 Jan;275(1):79-90.

PMID:
8118849
16.

Characterization and developmental expression of Tlx-1, the murine homolog of HOX11.

Raju K, Tang S, Dubé ID, Kamel-Reid S, Bryce DM, Breitman ML.

Mech Dev. 1993 Nov;44(1):51-64.

PMID:
7908826
19.

flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors.

Yamaguchi TP, Dumont DJ, Conlon RA, Breitman ML, Rossant J.

Development. 1993 Jun;118(2):489-98.

20.

The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors.

Dumont DJ, Gradwohl GJ, Fong GH, Auerbach R, Breitman ML.

Oncogene. 1993 May;8(5):1293-301.

PMID:
8386827
21.
22.
23.

Tumor necrosis factor alpha and interleukin 1 alpha induce anchorage independence in v-jun transgenic murine cells.

Vanhamme L, Marshall GM, Schuh AC, Breitman ML, Vogt PK.

Cancer Res. 1993 Feb 1;53(3):615-21.

25.

A frameshift mutation in the gamma E-crystallin gene of the Elo mouse.

Cartier M, Breitman ML, Tsui LC.

Nat Genet. 1992 Sep;2(1):42-5. Erratum in: Nat Genet 1992 Dec;2(4):343.

PMID:
1303247
26.

tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors.

Dumont DJ, Yamaguchi TP, Conlon RA, Rossant J, Breitman ML.

Oncogene. 1992 Aug;7(8):1471-80.

PMID:
1630810
27.

Embryology and morphology of microphthalmia in transgenic mice expressing a gamma F-crystallin/diphtheria toxin A hybrid gene.

Klein KL, Klintworth GK, Bernstein A, Breitman ML.

Lab Invest. 1992 Jul;67(1):31-41.

PMID:
1625446
28.

Temporal regulation of six crystallin transcripts during mouse lens development.

Goring DR, Breitman ML, Tsui LC.

Exp Eye Res. 1992 May;54(5):785-95.

PMID:
1623964
29.

Skeletal muscle arises as a late event during development of wound sarcomas in v-jun transgenic mice.

Schuh AC, Keating SJ, Yeung MC, Breitman ML.

Oncogene. 1992 Apr;7(4):667-76.

PMID:
1314368
30.
31.

Expression of S-antigen in retina, pineal gland, lens, and brain is directed by 5'-flanking sequences.

Breitman ML, Tsuda M, Usukura J, Kikuchi T, Zucconi A, Khoo W, Shinohara T.

J Biol Chem. 1991 Aug 15;266(23):15505-10.

32.
34.

Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice.

Schuh AC, Keating SJ, Monteclaro FS, Vogt PK, Breitman ML.

Nature. 1990 Aug 23;346(6286):756-60.

PMID:
2167455
35.

Genetic ablation in transgenic mice with an attenuated diphtheria toxin A gene.

Breitman ML, Rombola H, Maxwell IH, Klintworth GK, Bernstein A.

Mol Cell Biol. 1990 Feb;10(2):474-9.

36.

Asparagine-linked oligosaccharides associated with metastatic cancer.

Dennis JW, Laferté S, Yagel S, Breitman ML.

Cancer Cells. 1989 Nov;1(3):87-92. Review.

PMID:
2701653
37.

Evidence that beta 1-6 branched Asn-linked oligosaccharides on metastatic tumor cells facilitate invasion of basement membranes.

Yagel S, Feinmesser R, Waghorne C, Lala PK, Breitman ML, Dennis JW.

Int J Cancer. 1989 Oct 15;44(4):685-90.

PMID:
2507455
38.
39.

Analysis of lens cell fate and eye morphogenesis in transgenic mice ablated for cells of the lens lineage.

Breitman ML, Bryce DM, Giddens E, Clapoff S, Goring D, Tsui LC, Klintworth GK, Bernstein A.

Development. 1989 Jul;106(3):457-63.

40.

Multiple regulatory elements of the murine gamma 2-crystallin promoter.

Lok S, Stevens W, Breitman ML, Tsui LC.

Nucleic Acids Res. 1989 May 11;17(9):3563-82.

41.
42.

Genetic evidence for progressive selection and overgrowth of primary tumors by metastatic cell subpopulations.

Waghorne C, Thomas M, Lagarde A, Kerbel RS, Breitman ML.

Cancer Res. 1988 Nov 1;48(21):6109-14.

43.

The murine cataractogenic mutation, Cat Fraser, segregates independently of the gamma crystallin genes.

Rupert JL, Kuliszewki M, Tsui LC, Breitman ML, Gold RJ.

Genet Res. 1988 Feb;51(1):23-8. No abstract available.

PMID:
3366376
44.

Clonal dominance of primary tumours by metastatic cells: genetic analysis and biological implications.

Kerbel RS, Waghorne C, Korczak B, Lagarde A, Breitman ML.

Cancer Surv. 1988;7(4):597-629. Review.

PMID:
3072068
45.

Clonal changes in tumours during growth and progression evaluated by southern gel analysis of random integrations of foreign DNA.

Kerbel RS, Waghorne C, Korczak B, Breitman ML.

Ciba Found Symp. 1988;141:123-48. Review.

PMID:
2855413
46.

Analysis of growth, selection, and metastasis of tumor cell populations in vivo using random insertions of foreign DNA as genetic tags.

Waghorne C, Korczak B, Breitman ML, Kerbel RS.

Adv Exp Med Biol. 1988;233:27-37. No abstract available.

PMID:
2851927
47.

Genetic ablation: targeted expression of a toxin gene causes microphthalmia in transgenic mice.

Breitman ML, Clapoff S, Rossant J, Tsui LC, Glode LM, Maxwell IH, Bernstein A.

Science. 1987 Dec 11;238(4833):1563-5.

PMID:
3685993
49.

Relationship between proteins encoded by three human gamma-crystallin genes and distinct polypeptides in the eye lens.

Russell P, Meakin SO, Hohman TC, Tsui LC, Breitman ML.

Mol Cell Biol. 1987 Sep;7(9):3320-3.

50.

Gamma-crystallins of the human eye lens: expression analysis of five members of the gene family.

Meakin SO, Du RP, Tsui LC, Breitman ML.

Mol Cell Biol. 1987 Aug;7(8):2671-9.

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