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Items: 1 to 50 of 192

1.

Editorial: Cancer Models.

Breitenbach M, Hoffmann J.

Front Oncol. 2018 Oct 3;8:401. doi: 10.3389/fonc.2018.00401. eCollection 2018. No abstract available.

2.

The defense and signaling role of NADPH oxidases in eukaryotic cells : Review.

Breitenbach M, Rinnerthaler M, Weber M, Breitenbach-Koller H, Karl T, Cullen P, Basu S, Haskova D, Hasek J.

Wien Med Wochenschr. 2018 Sep;168(11-12):286-299. doi: 10.1007/s10354-018-0640-4. Epub 2018 Aug 6.

3.

Guidelines and recommendations on yeast cell death nomenclature.

Carmona-Gutierrez D, Bauer MA, Zimmermann A, Aguilera A, Austriaco N, Ayscough K, Balzan R, Bar-Nun S, Barrientos A, Belenky P, Blondel M, Braun RJ, Breitenbach M, Burhans WC, Büttner S, Cavalieri D, Chang M, Cooper KF, Côrte-Real M, Costa V, Cullin C, Dawes I, Dengjel J, Dickman MB, Eisenberg T, Fahrenkrog B, Fasel N, Fröhlich KU, Gargouri A, Giannattasio S, Goffrini P, Gourlay CW, Grant CM, Greenwood MT, Guaragnella N, Heger T, Heinisch J, Herker E, Herrmann JM, Hofer S, Jiménez-Ruiz A, Jungwirth H, Kainz K, Kontoyiannis DP, Ludovico P, Manon S, Martegani E, Mazzoni C, Megeney LA, Meisinger C, Nielsen J, Nyström T, Osiewacz HD, Outeiro TF, Park HO, Pendl T, Petranovic D, Picot S, Polčic P, Powers T, Ramsdale M, Rinnerthaler M, Rockenfeller P, Ruckenstuhl C, Schaffrath R, Segovia M, Severin FF, Sharon A, Sigrist SJ, Sommer-Ruck C, Sousa MJ, Thevelein JM, Thevissen K, Titorenko V, Toledano MB, Tuite M, Vögtle FN, Westermann B, Winderickx J, Wissing S, Wölfl S, Zhang ZJ, Zhao RY, Zhou B, Galluzzi L, Kroemer G, Madeo F.

Microb Cell. 2018 Jan 1;5(1):4-31. doi: 10.15698/mic2018.01.607. Review.

4.

The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy.

Schosserer M, Grillari J, Breitenbach M.

Front Oncol. 2017 Nov 23;7:278. doi: 10.3389/fonc.2017.00278. eCollection 2017. Review.

5.

Behead and live long or the tale of cathepsin L.

Streubel MK, Bischof J, Weiss R, Duschl J, Liedl W, Wimmer H, Breitenbach M, Weber M, Geltinger F, Richter K, Rinnerthaler M.

Yeast. 2018 Feb;35(2):237-249. doi: 10.1002/yea.3286. Epub 2017 Nov 29.

6.

Bridge-Induced Translocation between NUP145 and TOP2 Yeast Genes Models the Genetic Fusion between the Human Orthologs Associated With Acute Myeloid Leukemia.

Tosato V, West N, Zrimec J, Nikitin DV, Del Sal G, Marano R, Breitenbach M, Bruschi CV.

Front Oncol. 2017 Sep 29;7:231. doi: 10.3389/fonc.2017.00231. eCollection 2017.

7.

The Human NADPH Oxidase, Nox4, Regulates Cytoskeletal Organization in Two Cancer Cell Lines, HepG2 and SH-SY5Y.

Auer S, Rinnerthaler M, Bischof J, Streubel MK, Breitenbach-Koller H, Geisberger R, Aigner E, Cadamuro J, Richter K, Sopjani M, Haschke-Becher E, Felder TK, Breitenbach M.

Front Oncol. 2017 May 31;7:111. doi: 10.3389/fonc.2017.00111. eCollection 2017.

8.

Formaldehyde fixation is detrimental to actin cables in glucose-depleted S. cerevisiae cells.

Vasicova P, Rinnerthaler M, Haskova D, Novakova L, Malcova I, Breitenbach M, Hasek J.

Microb Cell. 2016 Apr 12;3(5):206-214. doi: 10.15698/mic2016.05.499.

9.

The control of translational accuracy is a determinant of healthy ageing in yeast.

von der Haar T, Leadsham JE, Sauvadet A, Tarrant D, Adam IS, Saromi K, Laun P, Rinnerthaler M, Breitenbach-Koller H, Breitenbach M, Tuite MF, Gourlay CW.

Open Biol. 2017 Jan;7(1). pii: 160291. doi: 10.1098/rsob.160291.

10.

Corrigendum: Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

Schosserer M, Minois N, Angerer TB, Amring M, Dellago H, Harreither E, Calle-Perez A, Pircher A, Peter Gerstl M, Pfeifenberger S, Brandl C, Sonntagbauer M, Kriegner A, Linder A, Weinhäusel A, Mohr T, Steiger M, Mattanovich D, Rinnerthaler M, Karl T, Sharma S, Entian KD, Kos M, Breitenbach M, Wilson IB, Polacek N, Grillari-Voglauer R, Breitenbach-Koller L, Grillari J.

Nat Commun. 2016 May 11;7:11530. doi: 10.1038/ncomms11530. No abstract available.

11.

High reactive oxygen species levels are detected at the end of the chronological life span of translocant yeast cells.

Sims J, Bruschi CV, Bertin C, West N, Breitenbach M, Schroeder S, Eisenberg T, Rinnerthaler M, Raspor P, Tosato V.

Mol Genet Genomics. 2016 Feb;291(1):423-35. doi: 10.1007/s00438-015-1120-9. Epub 2015 Sep 30.

PMID:
26423068
12.

Transcriptome and ultrastructural changes in dystrophic Epidermolysis bullosa resemble skin aging.

Breitenbach JS, Rinnerthaler M, Trost A, Weber M, Klausegger A, Gruber C, Bruckner D, Reitsamer HA, Bauer JW, Breitenbach M.

Aging (Albany NY). 2015 Jun;7(6):389-411.

13.

Introduction to Oxidative Stress in Biomedical and Biological Research.

Breitenbach M, Eckl P.

Biomolecules. 2015;5(2):1169-77.

14.

Oxidative stress in fungi: its function in signal transduction, interaction with plant hosts, and lignocellulose degradation.

Breitenbach M, Weber M, Rinnerthaler M, Karl T, Breitenbach-Koller L.

Biomolecules. 2015 Apr 3;5(2):318-42. doi: 10.3390/biom5020318. Review.

15.

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

Schosserer M, Minois N, Angerer TB, Amring M, Dellago H, Harreither E, Calle-Perez A, Pircher A, Gerstl MP, Pfeifenberger S, Brandl C, Sonntagbauer M, Kriegner A, Linder A, Weinhäusel A, Mohr T, Steiger M, Mattanovich D, Rinnerthaler M, Karl T, Sharma S, Entian KD, Kos M, Breitenbach M, Wilson IB, Polacek N, Grillari-Voglauer R, Breitenbach-Koller L, Grillari J.

Nat Commun. 2015 Jan 30;6:6158. doi: 10.1038/ncomms7158. Erratum in: Nat Commun. 2016 May 11;7:11530.

16.

The return of metabolism: biochemistry and physiology of the pentose phosphate pathway.

Stincone A, Prigione A, Cramer T, Wamelink MM, Campbell K, Cheung E, Olin-Sandoval V, Grüning NM, Krüger A, Tauqeer Alam M, Keller MA, Breitenbach M, Brindle KM, Rabinowitz JD, Ralser M.

Biol Rev Camb Philos Soc. 2015 Aug;90(3):927-63. doi: 10.1111/brv.12140. Epub 2014 Sep 22. Review.

17.

Chromosome translocation may lead to PRK1-dependent anticancer drug resistance in yeast via endocytic actin network deregulation.

Nikitin DV, Bruschi CV, Sims J, Breitenbach M, Rinnerthaler M, Tosato V.

Eur J Cell Biol. 2014 Apr;93(4):145-56. doi: 10.1016/j.ejcb.2014.03.003. Epub 2014 Apr 18.

PMID:
24846777
18.

Protein signatures of oxidative stress response in a patient specific cell line model for autism.

Chiocchetti AG, Haslinger D, Boesch M, Karl T, Wiemann S, Freitag CM, Poustka F, Scheibe B, Bauer JW, Hintner H, Breitenbach M, Kellermann J, Lottspeich F, Klauck SM, Breitenbach-Koller L.

Mol Autism. 2014 Feb 10;5(1):10. doi: 10.1186/2040-2392-5-10.

19.

Mitochondria in ageing: there is metabolism beyond the ROS.

Breitenbach M, Rinnerthaler M, Hartl J, Stincone A, Vowinckel J, Breitenbach-Koller H, Ralser M.

FEMS Yeast Res. 2014 Feb;14(1):198-212. doi: 10.1111/1567-1364.12134. Epub 2014 Jan 16. Review.

20.

Mmi1, the yeast homologue of mammalian TCTP, associates with stress granules in heat-shocked cells and modulates proteasome activity.

Rinnerthaler M, Lejskova R, Grousl T, Stradalova V, Heeren G, Richter K, Breitenbach-Koller L, Malinsky J, Hasek J, Breitenbach M.

PLoS One. 2013 Oct 28;8(10):e77791. doi: 10.1371/journal.pone.0077791. eCollection 2013.

21.

Saccharomyces cerevisiae genes involved in survival of heat shock.

Jarolim S, Ayer A, Pillay B, Gee AC, Phrakaysone A, Perrone GG, Breitenbach M, Dawes IW.

G3 (Bethesda). 2013 Dec 9;3(12):2321-33. doi: 10.1534/g3.113.007971.

22.

Maintenance of mitochondrial morphology by autophagy and its role in high glucose effects on chronological lifespan of Saccharomyces cerevisiae.

Aung-Htut MT, Lam YT, Lim YL, Rinnerthaler M, Gelling CL, Yang H, Breitenbach M, Dawes IW.

Oxid Med Cell Longev. 2013;2013:636287. doi: 10.1155/2013/636287. Epub 2013 Jul 11.

23.

Loss of cytochrome c oxidase promotes RAS-dependent ROS production from the ER resident NADPH oxidase, Yno1p, in yeast.

Leadsham JE, Sanders G, Giannaki S, Bastow EL, Hutton R, Naeimi WR, Breitenbach M, Gourlay CW.

Cell Metab. 2013 Aug 6;18(2):279-86. doi: 10.1016/j.cmet.2013.07.005.

24.

AMP-activated protein kinase signaling is upregulated in papillary thyroid cancer.

Vidal AP, Andrade BM, Vaisman F, Cazarin J, Pinto LF, Breitenbach MM, Corbo R, Caroli-Bottino A, Soares F, Vaisman M, Carvalho DP.

Eur J Endocrinol. 2013 Sep 17;169(4):521-8. doi: 10.1530/EJE-13-0284. Print 2013 Oct.

PMID:
23904275
25.

Superoxide radicals have a protective role during H2O2 stress.

Thorpe GW, Reodica M, Davies MJ, Heeren G, Jarolim S, Pillay B, Breitenbach M, Higgins VJ, Dawes IW.

Mol Biol Cell. 2013 Sep;24(18):2876-84. doi: 10.1091/mbc.E13-01-0052. Epub 2013 Jul 17.

26.

Specialized yeast ribosomes: a customized tool for selective mRNA translation.

Bauer JW, Brandl C, Haubenreisser O, Wimmer B, Weber M, Karl T, Klausegger A, Breitenbach M, Hintner H, von der Haar T, Tuite MF, Breitenbach-Koller L.

PLoS One. 2013 Jul 8;8(7):e67609. doi: 10.1371/journal.pone.0067609. Print 2013.

27.

The changing prevalence of autism in three regions of Canada.

Ouellette-Kuntz H, Coo H, Lam M, Breitenbach MM, Hennessey PE, Jackman PD, Lewis ME, Dewey D, Bernier FP, Chung AM.

J Autism Dev Disord. 2014 Jan;44(1):120-36. doi: 10.1007/s10803-013-1856-1.

PMID:
23771514
28.

Oxidative stress and neurodegeneration: the yeast model system.

Breitenbach M, Ralser M, Perrone GG, Iglseder B, Rinnerthaler M, Dawes IW.

Front Biosci (Landmark Ed). 2013 Jun 1;18:1174-93. Review.

PMID:
23747875
29.

Warburg effect and translocation-induced genomic instability: two yeast models for cancer cells.

Tosato V, Grüning NM, Breitenbach M, Arnak R, Ralser M, Bruschi CV.

Front Oncol. 2013 Jan 18;2:212. doi: 10.3389/fonc.2012.00212. eCollection 2012.

30.

The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt.

Ralser M, Kuhl H, Ralser M, Werber M, Lehrach H, Breitenbach M, Timmermann B.

Open Biol. 2012 Aug;2(8):120093. doi: 10.1098/rsob.120093.

31.

Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast.

Rinnerthaler M, Büttner S, Laun P, Heeren G, Felder TK, Klinger H, Weinberger M, Stolze K, Grousl T, Hasek J, Benada O, Frydlova I, Klocker A, Simon-Nobbe B, Jansko B, Breitenbach-Koller H, Eisenberg T, Gourlay CW, Madeo F, Burhans WC, Breitenbach M.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8658-63. doi: 10.1073/pnas.1201629109. Epub 2012 May 14.

32.

Correlates of age at diagnosis of autism spectrum disorders in six Canadian regions.

Coo H, Ouellette-Kuntz H, Lam M, Yu CT, Dewey D, Bernier FP, Chudley AE, Hennessey PE, Breitenbach MM, Noonan AL, Lewis ME, Holden JJ.

Chronic Dis Inj Can. 2012 Mar;32(2):90-100.

33.

Status report - National Epidemiologic Database for the Study of Autism in Canada (NEDSAC).

Ouellette-Kuntz H, Coo H, Yu CT, Lewis ME, Dewey D, Hennessey PE, Jackman PD, Breitenbach MM, Holden JJ.

Chronic Dis Inj Can. 2012 Mar;32(2):84-9. No abstract available.

34.

Sirtuins as regulators of the yeast metabolic network.

Ralser M, Michel S, Breitenbach M.

Front Pharmacol. 2012 Mar 8;3:32. doi: 10.3389/fphar.2012.00032. eCollection 2012.

35.

Yeast hypertrophy: cause or consequence of aging? Reply to Bilinski et al.

Ganley AR, Breitenbach M, Kennedy BK, Kobayashi T.

FEMS Yeast Res. 2012 May;12(3):267-8. doi: 10.1111/j.1567-1364.2012.00796.x. Epub 2012 Mar 29. No abstract available.

36.

Yeast aging and apoptosis.

Laun P, Büttner S, Rinnerthaler M, Burhans WC, Breitenbach M.

Subcell Biochem. 2012;57:207-32. doi: 10.1007/978-94-007-2561-4_10. Review.

PMID:
22094424
37.

The role of mitochondria in the aging processes of yeast.

Breitenbach M, Laun P, Dickinson JR, Klocker A, Rinnerthaler M, Dawes IW, Aung-Htut MT, Breitenbach-Koller L, Caballero A, Nyström T, Büttner S, Eisenberg T, Madeo F, Ralser M.

Subcell Biochem. 2012;57:55-78. doi: 10.1007/978-94-007-2561-4_3. Review.

PMID:
22094417
38.

Oxidative stresses and ageing.

Aung-Htut MT, Ayer A, Breitenbach M, Dawes IW.

Subcell Biochem. 2012;57:13-54. doi: 10.1007/978-94-007-2561-4_2. Review.

PMID:
22094416
39.

Introduction.

Breitenbach M, Laun P, Jazwinski SM.

Subcell Biochem. 2012;57:1-12. doi: 10.1007/978-94-007-2561-4_1. Review.

PMID:
22094415
40.

Vimentin and laminin are altered on cheek pouch microvessels of streptozotocin-induced diabetic hamsters.

Silva JF, Cyrino FZ, Breitenbach MM, Bouskela E, Carvalho JJ.

Clinics (Sao Paulo). 2011;66(11):1961-8.

41.

Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells.

Grüning NM, Rinnerthaler M, Bluemlein K, Mülleder M, Wamelink MM, Lehrach H, Jakobs C, Breitenbach M, Ralser M.

Cell Metab. 2011 Sep 7;14(3):415-27. doi: 10.1016/j.cmet.2011.06.017.

42.

A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis.

Büttner S, Ruli D, Vögtle FN, Galluzzi L, Moitzi B, Eisenberg T, Kepp O, Habernig L, Carmona-Gutierrez D, Rockenfeller P, Laun P, Breitenbach M, Khoury C, Fröhlich KU, Rechberger G, Meisinger C, Kroemer G, Madeo F.

EMBO J. 2011 Jun 14;30(14):2779-92. doi: 10.1038/emboj.2011.197.

43.

Identification of evolutionarily conserved genetic regulators of cellular aging.

Laschober GT, Ruli D, Hofer E, Muck C, Carmona-Gutierrez D, Ring J, Hutter E, Ruckenstuhl C, Micutkova L, Brunauer R, Jamnig A, Trimmel D, Herndler-Brandstetter D, Brunner S, Zenzmaier C, Sampson N, Breitenbach M, Fröhlich KU, Grubeck-Loebenstein B, Berger P, Wieser M, Grillari-Voglauer R, Thallinger GG, Grillari J, Trajanoski Z, Madeo F, Lepperdinger G, Jansen-Dürr P.

Aging Cell. 2010 Dec;9(6):1084-97. doi: 10.1111/j.1474-9726.2010.00637.x. Epub 2010 Oct 28.

44.

A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging.

Timmermann B, Jarolim S, Russmayer H, Kerick M, Michel S, Krüger A, Bluemlein K, Laun P, Grillari J, Lehrach H, Breitenbach M, Ralser M.

Aging (Albany NY). 2010 Aug;2(8):475-86.

45.

Candida albicans AGE3, the ortholog of the S. cerevisiae ARF-GAP-encoding gene GCS1, is required for hyphal growth and drug resistance.

Lettner T, Zeidler U, Gimona M, Hauser M, Breitenbach M, Bito A.

PLoS One. 2010 Aug 5;5(8):e11993. doi: 10.1371/journal.pone.0011993.

46.

Metabolic changes through hypoxia in humans and in yeast as a comparable cell model.

Netzer NC, Breitenbach M.

Sleep Breath. 2010 Sep;14(3):221-5. doi: 10.1007/s11325-010-0342-7. Epub 2010 Jun 10. Review.

PMID:
20535573
47.

Crystal structure of the NADP-dependent mannitol dehydrogenase from Cladosporium herbarum: Implications for oligomerisation and catalysis.

Nüss D, Goettig P, Magler I, Denk U, Breitenbach M, Schneider PB, Brandstetter H, Simon-Nobbe B.

Biochimie. 2010 Aug;92(8):985-93. doi: 10.1016/j.biochi.2010.04.012. Epub 2010 Apr 24.

PMID:
20420880
48.

Quantitation of (a)symmetric inheritance of functional and of oxidatively damaged mitochondrial aconitase in the cell division of old yeast mother cells.

Klinger H, Rinnerthaler M, Lam YT, Laun P, Heeren G, Klocker A, Simon-Nobbe B, Dickinson JR, Dawes IW, Breitenbach M.

Exp Gerontol. 2010 Aug;45(7-8):533-42. doi: 10.1016/j.exger.2010.03.016. Epub 2010 Apr 8.

PMID:
20382214
49.

The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.

Heeren G, Rinnerthaler M, Laun P, von Seyerl P, Kössler S, Klinger H, Hager M, Bogengruber E, Jarolim S, Simon-Nobbe B, Schüller C, Carmona-Gutierrez D, Breitenbach-Koller L, Mück C, Jansen-Dürr P, Criollo A, Kroemer G, Madeo F, Breitenbach M.

Aging (Albany NY). 2009 Jul 13;1(7):622-36.

50.

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging.

Hackl M, Brunner S, Fortschegger K, Schreiner C, Micutkova L, Mück C, Laschober GT, Lepperdinger G, Sampson N, Berger P, Herndler-Brandstetter D, Wieser M, Kühnel H, Strasser A, Rinnerthaler M, Breitenbach M, Mildner M, Eckhart L, Tschachler E, Trost A, Bauer JW, Papak C, Trajanoski Z, Scheideler M, Grillari-Voglauer R, Grubeck-Loebenstein B, Jansen-Dürr P, Grillari J.

Aging Cell. 2010 Apr;9(2):291-6. doi: 10.1111/j.1474-9726.2010.00549.x. Epub 2010 Jan 18.

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