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Items: 30


Rbpj expression in regulatory T cells is critical for restraining TH2 responses.

Delacher M, Schmidl C, Herzig Y, Breloer M, Hartmann W, Brunk F, Kägebein D, Träger U, Hofer AC, Bittner S, Weichenhan D, Imbusch CD, Hotz-Wagenblatt A, Hielscher T, Breiling A, Federico G, Gröne HJ, Schmid RM, Rehli M, Abramson J, Feuerer M.

Nat Commun. 2019 Apr 8;10(1):1621. doi: 10.1038/s41467-019-09276-w.


DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries.

Wiehle L, Thorn GJ, Raddatz G, Clarkson CT, Rippe K, Lyko F, Breiling A, Teif VB.

Genome Res. 2019 May;29(5):750-761. doi: 10.1101/gr.239707.118. Epub 2019 Apr 4.


Corrigendum: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.

Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M.

Nat Immunol. 2017 Nov 16;18(12):1361. doi: 10.1038/ni1217-1361b.


Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.

Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M.

Nat Immunol. 2017 Oct;18(10):1160-1172. doi: 10.1038/ni.3799. Epub 2017 Aug 7. Erratum in: Nat Immunol. 2017 Nov 16;18(12 ):1361.


Measurement of Cellular Behavior by Electrochemical Impedance Sensing.

Öz S, Breiling A, Maercker C.

Methods Mol Biol. 2017;1601:267-273. doi: 10.1007/978-1-4939-6960-9_21.


Transcriptional programs that control expression of the autoimmune regulator gene Aire.

Herzig Y, Nevo S, Bornstein C, Brezis MR, Ben-Hur S, Shkedy A, Eisenberg-Bord M, Levi B, Delacher M, Goldfarb Y, David E, Weinberger L, Viukov S, Ben-Dor S, Giraud M, Hanna JH, Breiling A, Lyko F, Amit I, Feuerer M, Abramson J.

Nat Immunol. 2017 Feb;18(2):161-172. doi: 10.1038/ni.3638. Epub 2016 Dec 12.


Chromatin Immunoprecipitation.

Wiehle L, Breiling A.

Methods Mol Biol. 2016;1480:7-21. doi: 10.1007/978-1-4939-6380-5_2.


Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation.

Wiehle L, Raddatz G, Musch T, Dawlaty MM, Jaenisch R, Lyko F, Breiling A.

Mol Cell Biol. 2015 Nov 23;36(3):452-61. doi: 10.1128/MCB.00587-15. Print 2016 Feb 1.


Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyond.

Breiling A, Lyko F.

Epigenetics Chromatin. 2015 Jul 21;8:24. doi: 10.1186/s13072-015-0016-6. eCollection 2015. Review.


Chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer.

Abu-Remaileh M, Bender S, Raddatz G, Ansari I, Cohen D, Gutekunst J, Musch T, Linhart H, Breiling A, Pikarsky E, Bergman Y, Lyko F.

Cancer Res. 2015 May 15;75(10):2120-30. doi: 10.1158/0008-5472.CAN-14-3295. Epub 2015 Mar 25.


Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.

Dawlaty MM, Breiling A, Le T, Barrasa MI, Raddatz G, Gao Q, Powell BE, Cheng AW, Faull KF, Lyko F, Jaenisch R.

Dev Cell. 2014 Apr 14;29(1):102-11. doi: 10.1016/j.devcel.2014.03.003.


RNA-interference components are dispensable for transcriptional silencing of the drosophila bithorax-complex.

Cernilogar FM, Burroughs AM, Lanzuolo C, Breiling A, Imhof A, Orlando V.

PLoS One. 2013 Jun 13;8(6):e65740. doi: 10.1371/journal.pone.0065740. Print 2013.


Embryonic carcinoma cells show specific dielectric resistance profiles during induced differentiation.

Öz S, Maercker C, Breiling A.

PLoS One. 2013;8(3):e59895. doi: 10.1371/journal.pone.0059895. Epub 2013 Mar 22.


Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.

Dawlaty MM, Breiling A, Le T, Raddatz G, Barrasa MI, Cheng AW, Gao Q, Powell BE, Li Z, Xu M, Faull KF, Lyko F, Jaenisch R.

Dev Cell. 2013 Feb 11;24(3):310-23. doi: 10.1016/j.devcel.2012.12.015. Epub 2013 Jan 24.


MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma.

Castro IC, Breiling A, Luetkenhaus K, Ceteci F, Hausmann S, Kress S, Lyko F, Rudel T, Rapp UR.

Mol Cancer Res. 2013 Feb;11(2):161-72. doi: 10.1158/1541-7786.MCR-12-0414-T. Epub 2012 Dec 13.


Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster.

Bocker MT, Tuorto F, Raddatz G, Musch T, Yang FC, Xu M, Lyko F, Breiling A.

Nat Commun. 2012 May 8;3:818. doi: 10.1038/ncomms1826.


Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila.

Cernilogar FM, Onorati MC, Kothe GO, Burroughs AM, Parsi KM, Breiling A, Lo Sardo F, Saxena A, Miyoshi K, Siomi H, Siomi MC, Carninci P, Gilmour DS, Corona DF, Orlando V.

Nature. 2011 Nov 6;480(7377):391-5. doi: 10.1038/nature10492.


Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging.

Bocker MT, Hellwig I, Breiling A, Eckstein V, Ho AD, Lyko F.

Blood. 2011 May 12;117(19):e182-9. doi: 10.1182/blood-2011-01-331926. Epub 2011 Mar 22.


Binding Sights in Chromatin by X-ChIP.

Breiling A, Orlando V.

Mapping Protein/DNA Interactions by Cross-Linking [Internet]. Paris: Institut national de la santé et de la recherche médicale; 2001.


Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells.

de Souza Rocha Simonini P, Breiling A, Gupta N, Malekpour M, Youns M, Omranipour R, Malekpour F, Volinia S, Croce CM, Najmabadi H, Diederichs S, Sahin O, Mayer D, Lyko F, Hoheisel JD, Riazalhosseini Y.

Cancer Res. 2010 Nov 15;70(22):9175-84. doi: 10.1158/0008-5472.CAN-10-1318. Epub 2010 Oct 26.


Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors.

Musch T, Oz Y, Lyko F, Breiling A.

PLoS One. 2010 May 19;5(5):e10726. doi: 10.1371/journal.pone.0010726.


Biology of polycomb and trithorax group proteins.

Breiling A, Sessa L, Orlando V.

Int Rev Cytol. 2007;258:83-136. Review.


Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster.

Sessa L, Breiling A, Lavorgna G, Silvestri L, Casari G, Orlando V.

RNA. 2007 Feb;13(2):223-39. Epub 2006 Dec 21.


Chromatin Immunoprecipitation (ChIP) of Protein Complexes: Mapping of Genomic Targets of Nuclear Proteins in Cultured Cells.

Breiling A, Orlando V.

CSH Protoc. 2006 Sep 1;2006(4). pii: pdb.prot4560. doi: 10.1101/pdb.prot4560.


Epigenome changes in active and inactive polycomb-group-controlled regions.

Breiling A, O'Neill LP, D'Eliseo D, Turner BM, Orlando V.

EMBO Rep. 2004 Oct;5(10):976-82. Epub 2004 Sep 24.


SET domain proteins reSET gene expression.

Breiling A, Orlando V.

Nat Struct Biol. 2002 Dec;9(12):894-6. No abstract available.


The maternal effect gene, abnormal oocyte (abo), of Drosophila melanogaster encodes a specific negative regulator of histones.

Berloco M, Fanti L, Breiling A, Orlando V, Pimpinelli S.

Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12126-31. Epub 2001 Oct 2.


General transcription factors bind promoters repressed by Polycomb group proteins.

Breiling A, Turner BM, Bianchi ME, Orlando V.

Nature. 2001 Aug 9;412(6847):651-5.


The Drosophila polycomb protein interacts with nucleosomal core particles In vitro via its repression domain.

Breiling A, Bonte E, Ferrari S, Becker PB, Paro R.

Mol Cell Biol. 1999 Dec;19(12):8451-60.

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