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Items: 15


Novel roles for two-component regulatory systems in cytotoxicity and virulence-related properties in Pseudomonas aeruginosa.

Gellatly SL, Bains M, Breidenstein EBM, Strehmel J, Reffuveille F, Taylor PK, Yeung ATY, Overhage J, Hancock REW.

AIMS Microbiol. 2018 Mar 8;4(1):173-191. doi: 10.3934/microbiol.2018.1.173. eCollection 2018.


Two Isoforms of Clp Peptidase in Pseudomonas aeruginosa Control Distinct Aspects of Cellular Physiology.

Hall BM, Breidenstein EBM, de la Fuente-Núñez C, Reffuveille F, Mawla GD, Hancock REW, Baker TA.

J Bacteriol. 2017 Jan 12;199(3). pii: e00568-16. doi: 10.1128/JB.00568-16. Print 2017 Feb 1.


Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa.

Fernández L, Breidenstein EBM, Taylor PK, Bains M, de la Fuente-Núñez C, Fang Y, Foster LJ, Hancock REW.

Sci Rep. 2016 May 27;6:26811. doi: 10.1038/srep26811.


Antimicrobial Activity of Plectasin NZ2114 in Combination with Cell Wall Targeting Antibiotics Against VanA-Type Enterococcus faecalis.

Breidenstein EB, Courvalin P, Meziane-Cherif D.

Microb Drug Resist. 2015 Aug;21(4):373-9. doi: 10.1089/mdr.2014.0221. Epub 2015 Mar 18.


Anti-Biofilm and Immunomodulatory Activities of Peptides That Inhibit Biofilms Formed by Pathogens Isolated from Cystic Fibrosis Patients.

de la Fuente-Núñez C, Mansour SC, Wang Z, Jiang L, Breidenstein EB, Elliott M, Reffuveille F, Speert DP, Reckseidler-Zenteno SL, Shen Y, Haapasalo M, Hancock RE.

Antibiotics (Basel). 2014;3(4):509-26. doi: 10.3390/antibiotics3040509.


Armand-Frappier outstanding student award -- role of ATP-dependent proteases in antibiotic resistance and virulence.

Breidenstein EB, Hancock RE.

Can J Microbiol. 2013 Jan;59(1):1-8. doi: 10.1139/cjm-2012-0681. Epub 2012 Nov 21. Review.


The Lon protease is essential for full virulence in Pseudomonas aeruginosa.

Breidenstein EB, Janot L, Strehmel J, Fernandez L, Taylor PK, Kukavica-Ibrulj I, Gellatly SL, Levesque RC, Overhage J, Hancock RE.

PLoS One. 2012;7(11):e49123. doi: 10.1371/journal.pone.0049123. Epub 2012 Nov 7.


Involvement of the lon protease in the SOS response triggered by ciprofloxacin in Pseudomonas aeruginosa PAO1.

Breidenstein EB, Bains M, Hancock RE.

Antimicrob Agents Chemother. 2012 Jun;56(6):2879-87. doi: 10.1128/AAC.06014-11. Epub 2012 Mar 26.


Inhibition of bacterial biofilm formation and swarming motility by a small synthetic cationic peptide.

de la Fuente-Núñez C, Korolik V, Bains M, Nguyen U, Breidenstein EB, Horsman S, Lewenza S, Burrows L, Hancock RE.

Antimicrob Agents Chemother. 2012 May;56(5):2696-704. doi: 10.1128/AAC.00064-12. Epub 2012 Feb 21.


Role of intracellular proteases in the antibiotic resistance, motility, and biofilm formation of Pseudomonas aeruginosa.

Fernández L, Breidenstein EB, Song D, Hancock RE.

Antimicrob Agents Chemother. 2012 Feb;56(2):1128-32. doi: 10.1128/AAC.05336-11. Epub 2011 Nov 28.


Pseudomonas aeruginosa: all roads lead to resistance.

Breidenstein EB, de la Fuente-Núñez C, Hancock RE.

Trends Microbiol. 2011 Aug;19(8):419-26. doi: 10.1016/j.tim.2011.04.005. Epub 2011 Jun 12. Review.


Creeping baselines and adaptive resistance to antibiotics.

Fernández L, Breidenstein EB, Hancock RE.

Drug Resist Updat. 2011 Feb;14(1):1-21. doi: 10.1016/j.drup.2011.01.001. Epub 2011 Feb 1. Review.


Complex ciprofloxacin resistome revealed by screening a Pseudomonas aeruginosa mutant library for altered susceptibility.

Breidenstein EB, Khaira BK, Wiegand I, Overhage J, Hancock RE.

Antimicrob Agents Chemother. 2008 Dec;52(12):4486-91. doi: 10.1128/AAC.00222-08. Epub 2008 Sep 29.


Mutator genes giving rise to decreased antibiotic susceptibility in Pseudomonas aeruginosa.

Wiegand I, Marr AK, Breidenstein EB, Schurek KN, Taylor P, Hancock RE.

Antimicrob Agents Chemother. 2008 Oct;52(10):3810-3. doi: 10.1128/AAC.00233-08. Epub 2008 Jul 28.


Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin.

Brazas MD, Breidenstein EB, Overhage J, Hancock RE.

Antimicrob Agents Chemother. 2007 Dec;51(12):4276-83. Epub 2007 Sep 24.

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