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Items: 47

1.

Capturing the natural diversity of the human antibody response against vaccinia virus.

Lantto J, Haahr Hansen M, Rasmussen SK, Steinaa L, Poulsen TR, Duggan J, Dennis M, Naylor I, Easterbrook L, Bregenholt S, Haurum J, Jensen A.

J Virol. 2011 Feb;85(4):1820-33. doi: 10.1128/JVI.02127-10. Epub 2010 Dec 8.

2.

Reduced susceptibility of recombinant polyclonal antibodies to inhibitory anti-variable domain antibody responses.

Klitgaard JL, Coljee VW, Andersen PS, Rasmussen LK, Nielsen LS, Haurum JS, Bregenholt S.

J Immunol. 2006 Sep 15;177(6):3782-90.

3.

Development of recombinant human polyclonal antibodies for the treatment of complex human diseases.

Tolstrup AB, Frandsen TP, Bregenholt S.

Expert Opin Biol Ther. 2006 Sep;6(9):905-12. Review.

PMID:
16918257
4.

Recombinant human polyclonal antibodies: A new class of therapeutic antibodies against viral infections.

Bregenholt S, Jensen A, Lantto J, Hyldig S, Haurum JS.

Curr Pharm Des. 2006;12(16):2007-15. Review.

PMID:
16787244
5.

Allergen-specific polyclonal antibodies reduce allergic disease in a mouse model of allergic asthma.

Moerch U, Haahr Hansen M, Vest Hansen NJ, Rasmussen LK, Oleksiewicz MB, Frandsen TP, Haurum JS, Bregenholt S.

Int Arch Allergy Immunol. 2006;140(3):261-9. Epub 2006 May 11.

PMID:
16699287
6.

Production of target-specific recombinant human polyclonal antibodies in mammalian cells.

Wiberg FC, Rasmussen SK, Frandsen TP, Rasmussen LK, Tengbjerg K, Coljee VW, Sharon J, Yang CY, Bregenholt S, Nielsen LS, Haurum JS, Tolstrup AB.

Biotechnol Bioeng. 2006 Jun 5;94(2):396-405.

PMID:
16596663
7.

Extensive restrictions in the VH sequence usage of the human antibody response against the Rhesus D antigen.

Andersen PS, Haahr-Hansen M, Coljee VW, Hinnerfeldt FR, Varming K, Bregenholt S, Haurum JS.

Mol Immunol. 2007 Jan;44(4):412-22. Epub 2006 Apr 3.

PMID:
16581131
8.

Isolation of human antibody repertoires with preservation of the natural heavy and light chain pairing.

Meijer PJ, Andersen PS, Haahr Hansen M, Steinaa L, Jensen A, Lantto J, Oleksiewicz MB, Tengbjerg K, Poulsen TR, Coljee VW, Bregenholt S, Haurum JS, Nielsen LS.

J Mol Biol. 2006 May 5;358(3):764-72. Epub 2006 Mar 2.

PMID:
16563430
9.

Invariant V alpha 14+ NKT cells participate in the early response to enteric Listeria monocytogenes infection.

Ranson T, Bregenholt S, Lehuen A, Gaillot O, Leite-de-Moraes MC, Herbelin A, Berche P, Di Santo JP.

J Immunol. 2005 Jul 15;175(2):1137-44.

10.

Recombinant polyclonal antibodies: therapeutic antibody technologies come full circle.

Haurum J, Bregenholt S.

IDrugs. 2005 May;8(5):404-9. Review.

PMID:
15883923
11.

The long-acting glucagon-like peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro.

Bregenholt S, Møldrup A, Blume N, Karlsen AE, Nissen Friedrichsen B, Tornhave D, Knudsen LB, Petersen JS.

Biochem Biophys Res Commun. 2005 May 6;330(2):577-84.

PMID:
15796922
12.

Pathogen-specific recombinant human polyclonal antibodies: biodefence applications.

Bregenholt S, Haurum J.

Expert Opin Biol Ther. 2004 Mar;4(3):387-96. Review.

PMID:
15006732
13.

Coupling of oral human or porcine insulin to the B subunit of cholera toxin (CTB) overcomes critical antigenic differences for prevention of type I diabetes.

Petersen JS, Bregenholt S, Apostolopolous V, Homann D, Wolfe T, Hughes A, De Jongh K, Wang M, Dyrberg T, Von Herrath MG.

Clin Exp Immunol. 2003 Oct;134(1):38-45.

14.

The cholera toxin B subunit directly costimulates antigen-primed CD4+ T cells ex vivo.

Wang M, Bregenholt S, Petersen JS.

Scand J Immunol. 2003 Sep;58(3):342-9.

15.

The cholera toxin B subunit is a mucosal adjuvant for oral tolerance induction in type 1 diabetes.

Bregenholt S, Wang M, Wolfe T, Hughes A, Baerentzen L, Dyrberg T, von Herrath MG, Petersen JS.

Scand J Immunol. 2003 May;57(5):432-8.

16.
17.

A new model for analyzing immunomodulation of T cell responses induced by oral administration of islet cell antigens.

Bregenholt S, Wang M, Zdravkovic M, Dyrberg T, Petersen JS.

Ann N Y Acad Sci. 2002 Apr;958:179-81.

PMID:
12021102
18.

No evidence for altered cellular immune functions in personnel deployed in the Persian Gulf during and after the Gulf War--The Danish Gulf War study.

Bregenholt S, Ishøy T, Skovgaard LT, Suadicani P, Appleyard M, Guldager B, Malte L, Gyntelberg F, Claesson MH.

APMIS. 2001 Jul-Aug;109(7-8):517-24.

PMID:
11552949
19.

The majority of lamina propria CD4(+) T-cells from scid mice with colitis undergo Fas-mediated apoptosis in vivo.

Bregenholt S, Petersen TR, Claesson MH.

Immunol Lett. 2001 Aug 1;78(1):7-12.

PMID:
11470145
20.
21.

Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms.

Colucci F, Rosmaraki E, Bregenholt S, Samson SI, Di Bartolo V, Turner M, Vanes L, Tybulewicz V, Di Santo JP.

J Exp Med. 2001 Jun 18;193(12):1413-24.

22.

Transforming growth factor-beta messenger RNA and protein in murine colitis.

Whiting CV, Williams AM, Claesson MH, Bregenholt S, Reimann J, Bland PW.

J Histochem Cytochem. 2001 Jun;49(6):727-38.

PMID:
11373319
23.

Conventional alpha beta T cells are sufficient for innate and adaptive immunity against enteric Listeria monocytogenes.

Bregenholt S, Berche P, Brombacher F, Di Santo JP.

J Immunol. 2001 Feb 1;166(3):1871-6.

24.

The role of up-regulated serine proteases and matrix metalloproteinases in the pathogenesis of a murine model of colitis.

Tarlton JF, Whiting CV, Tunmore D, Bregenholt S, Reimann J, Claesson MH, Bland PW.

Am J Pathol. 2000 Dec;157(6):1927-35.

25.
26.
27.

The ClpP serine protease is essential for the intracellular parasitism and virulence of Listeria monocytogenes.

Gaillot O, Pellegrini E, Bregenholt S, Nair S, Berche P.

Mol Microbiol. 2000 Mar;35(6):1286-94.

28.

The CC-chemokine receptor 5 (CCR5) is a marker of, but not essential for the development of human Th1 cells.

Odum N, Bregenholt S, Eriksen KW, Skov S, Ryder LP, Bendtzen K, Van Neerven RJ, Svejgaard A, Garred P.

Tissue Antigens. 1999 Dec;54(6):572-7.

PMID:
10674971
29.
30.

Signal transduction by the major histocompatibility complex class I molecule.

Pedersen AE, Skov S, Bregenholt S, Ruhwald M, Claesson MH.

APMIS. 1999 Oct;107(10):887-95. Review.

PMID:
10549585
31.

MHC-I-induced apoptosis in human B-lymphoma cells is dependent on protein tyrosine and serine/threonine kinases.

Pedersen AE, Bregenholt S, Johansen B, Skov S, Claesson MH.

Exp Cell Res. 1999 Aug 25;251(1):128-34.

PMID:
10438578
32.

Tumour necrosis factor-alpha (TNF-alpha) transcription and translation in the CD4+ T cell-transplanted scid mouse model of colitis.

Williams AM, Whiting CV, Bonhagen K, Reimann J, Bregenholt S, Claesson MH, Bland PW.

Clin Exp Immunol. 1999 Jun;116(3):415-24.

33.

Colitis-inducing potency of CD4+ T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype.

Claesson MH, Bregenholt S, Bonhagen K, Thoma S, Möller P, Grusby MJ, Leithäuser F, Nissen MH, Reimann J.

J Immunol. 1999 Mar 15;162(6):3702-10.

34.

Proliferation and apoptosis of lamina propria CD4+ T cells from scid mice with inflammatory bowel disease.

Bregenholt S, Reimann J, Claesson MH.

Eur J Immunol. 1998 Nov;28(11):3655-63.

36.

Inflammatory bowel disease: potential therapeutic strategies.

Nielsen OH, Vainer B, Bregenholt S, Claësson MH, Bishop PD, Kirman I.

Cytokines Cell Mol Ther. 1997 Dec;3(4):267-81. Review.

PMID:
9740355
37.
38.

Protein tyrosine kinases p53/56lyn and p72syk in MHC class I-mediated signal transduction in B lymphoma cells.

Pedersen AE, Bregenholt S, Skov S, Vrang ML, Claesson MH.

Exp Cell Res. 1998 Apr 10;240(1):144-50.

PMID:
9570929
39.

C1-esterase inhibitor blocks T lymphocyte proliferation and cytotoxic T lymphocyte generation in vitro.

Nissen MH, Bregenholt S, Nording JA, Claesson MH.

Int Immunol. 1998 Feb;10(2):167-73.

PMID:
9533444
40.

Increased intracellular Th1 cytokines in scid mice with inflammatory bowel disease.

Bregenholt S, Claesson MH.

Eur J Immunol. 1998 Jan;28(1):379-89.

42.

T-cell transfer and cytokine/TCR gene deletion models in the study of inflammatory bowel disease.

Bregenholt S, Delbro D, Claesson MH.

APMIS. 1997 Sep;105(9):655-62. Review.

PMID:
9350208
44.

Cytotoxic reactivity of gut lamina propria CD4+ alpha beta T cells in SCID mice with colitis.

Bonhagen K, Thoma S, Bland P, Bregenholt S, Rudolphi A, Claesson MH, Reimann J.

Eur J Immunol. 1996 Dec;26(12):3074-83.

PMID:
8977307
45.

MHC class I phenotype and function of human beta 2-microglobulin transgenic murine lymphocytes.

Bjerager L, Pedersen LO, Bregenholt S, Nissen MH, Claesson MH.

Scand J Immunol. 1996 Dec;44(6):615-22.

PMID:
8972744
46.

Ligation of MHC class I molecules on peripheral blood T lymphocytes induces new phenotypes and functions.

Bregenholt S, Röpke M, Skov S, Claesson MH.

J Immunol. 1996 Aug 1;157(3):993-9.

PMID:
8757602
47.

An improved method for the detection of peptide-induced upregulation of HLA-A2 molecules on TAP-deficient T2 cells.

Regner M, Claësson MH, Bregenholt S, Röpke M.

Exp Clin Immunogenet. 1996;13(1):30-5.

PMID:
8854086

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