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Items: 1 to 50 of 116

1.

Report on the current status of the use of real-world data (RWD) and real-world evidence (RWE) in drug development and regulation.

Breckenridge AM, Breckenridge RA, Peck CC.

Br J Clin Pharmacol. 2019 Sep;85(9):1874-1877. doi: 10.1111/bcp.14026. Epub 2019 Jul 10.

PMID:
31290181
2.

Response of protein S100B to playing American football, lifting weights, and treadmill running.

Rogatzki MJ, Keuler SA, Harris AE, Ringgenberg SW, Breckenridge RE, White JL, Baker JS.

Scand J Med Sci Sports. 2018 Dec;28(12):2505-2514. doi: 10.1111/sms.13297. Epub 2018 Oct 1.

PMID:
30203865
3.

Resistant Hypertension: Trials and Tribulations.

George MJ, Marks DJB, Rezk T, Breckenridge R, Sofat R, Martin J, MacAllister R, Touyz RM, Staessen JA, Bursztyn M, Lappin D, Barigou M, Hingorani A.

Hypertension. 2018 May;71(5):772-780. doi: 10.1161/HYPERTENSIONAHA.118.10864. Epub 2018 Apr 2. Review. No abstract available.

PMID:
29610269
4.

Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology.

Lovering RC, Roncaglia P, Howe DG, Laulederkind SJF, Khodiyar VK, Berardini TZ, Tweedie S, Foulger RE, Osumi-Sutherland D, Campbell NH, Huntley RP, Talmud PJ, Blake JA, Breckenridge R, Riley PR, Lambiase PD, Elliott PM, Clapp L, Tinker A, Hill DP.

Circ Genom Precis Med. 2018 Feb;11(2):e001813. doi: 10.1161/CIRCGEN.117.001813.

5.

Biomarkers of brain injury following an American football game: A pilot study.

Rogatzki MJ, Soja SE, McCabe CA, Breckenridge RE, White JL, Baker JS.

Int J Immunopathol Pharmacol. 2016 Sep;29(3):450-7. doi: 10.1177/0394632016657091. Epub 2016 Jul 7.

6.

External validity of trials should be taken into account before asthma drug candidates reach market authorisation.

Briasoulis O, Breckenridge R, Nunn A.

Lancet Respir Med. 2016 Aug;4(8):601-603. doi: 10.1016/S2213-2600(16)30118-7. Epub 2016 May 27. No abstract available.

PMID:
27245917
7.

Absence of the Regulator of G-protein Signaling, RGS4, Predisposes to Atrial Fibrillation and Is Associated with Abnormal Calcium Handling.

Opel A, Nobles M, Montaigne D, Finlay M, Anderson N, Breckenridge R, Tinker A.

J Biol Chem. 2015 Jul 31;290(31):19233-44. doi: 10.1074/jbc.M115.666719. Epub 2015 Jun 18.

8.

Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release.

Komarowska I, Coe D, Wang G, Haas R, Mauro C, Kishore M, Cooper D, Nadkarni S, Fu H, Steinbruchel DA, Pitzalis C, Anderson G, Bucy P, Lombardi G, Breckenridge R, Marelli-Berg FM.

Immunity. 2015 Jun 16;42(6):1087-99. doi: 10.1016/j.immuni.2015.05.014. Epub 2015 Jun 9.

9.

Myosin heavy chain 15 is associated with bovine pulmonary arterial pressure.

Neary MT, Neary JM, Lund GK, Holt TN, Garry FB, Mohun TJ, Breckenridge RA.

Pulm Circ. 2014 Sep;4(3):496-503. doi: 10.1086/677364.

10.

Technical note: A comparison of DNA collection methods in cattle and yaks.

Neary MT, Neary JM, Lund GK, Garry FB, Holt TN, Mohun TJ, Breckenridge RA.

J Anim Sci. 2014 Sep;92(9):3811-5. doi: 10.2527/jas.2013-7445. Epub 2014 Aug 1.

PMID:
25085402
11.

Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function.

Neary MT, Ng KE, Ludtmann MH, Hall AR, Piotrowska I, Ong SB, Hausenloy DJ, Mohun TJ, Abramov AY, Breckenridge RA.

J Mol Cell Cardiol. 2014 Sep;74:340-52. doi: 10.1016/j.yjmcc.2014.06.013. Epub 2014 Jun 28.

12.

Induction of the calcineurin variant CnAβ1 after myocardial infarction reduces post-infarction ventricular remodelling by promoting infarct vascularization.

López-Olañeta MM, Villalba M, Gómez-Salinero JM, Jiménez-Borreguero LJ, Breckenridge R, Ortiz-Sánchez P, García-Pavía P, Ibáñez B, Lara-Pezzi E.

Cardiovasc Res. 2014 Jun 1;102(3):396-406. doi: 10.1093/cvr/cvu068. Epub 2014 Mar 25.

PMID:
24667850
13.

Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research.

Hohl M, Ardehali H, Azuaje FJ, Breckenridge RA, Doehner W, Eaton P, Ehret GB, Fujita T, Gaetani R, Giacca M, Hasenfuß G, Heymans S, Leite-Moreira AF, Linke WA, Linz D, Lyon A, Mamas MA, Orešič M, Papp Z, Pedrazzini T, Piepoli M, Prosser B, Rizzuto R, Tarone G, Tian R, van Craenenbroeck E, van Rooij E, Wai T, Weiss G, Maack C.

Eur J Heart Fail. 2014 Jan;16(1):6-14. doi: 10.1002/ejhf.10. Epub 2013 Dec 14. Review. No abstract available.

14.

Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism.

Breckenridge RA, Piotrowska I, Ng KE, Ragan TJ, West JA, Kotecha S, Towers N, Bennett M, Kienesberger PC, Smolenski RT, Siddall HK, Offer JL, Mocanu MM, Yelon DM, Dyck JR, Griffin JL, Abramov AY, Gould AP, Mohun TJ.

PLoS Biol. 2013 Sep;11(9):e1001666. doi: 10.1371/journal.pbio.1001666. Epub 2013 Sep 24. Erratum in: PLoS Biol. 2013 Dec;11(12). doi:10.1371/annotation/a9a7f37a-3fa7-4f7f-8310-1339bf5a666e.

15.

Hypoxia at the heart of sudden infant death syndrome?

Neary MT, Breckenridge RA.

Pediatr Res. 2013 Oct;74(4):375-9. doi: 10.1038/pr.2013.122. Epub 2013 Jul 17. Review.

16.

Abundance, distribution, mobility and oligomeric state of M₂ muscarinic acetylcholine receptors in live cardiac muscle.

Nenasheva TA, Neary M, Mashanov GI, Birdsall NJ, Breckenridge RA, Molloy JE.

J Mol Cell Cardiol. 2013 Apr;57:129-36. doi: 10.1016/j.yjmcc.2013.01.009. Epub 2013 Jan 25.

17.

Prescribing Errors in UK Hospitals: Problems and Solutions.

Breckenridge RA.

Ann Med Surg (Lond). 2012 Feb 18;2(1):1-2. doi: 10.1016/S2049-0801(13)70016-5. eCollection 2013. No abstract available.

18.

From zebrafish heart jogging genes to mouse and human orthologs: using Gene Ontology to investigate mammalian heart development.

Khodiyar VK, Howe D, Talmud PJ, Breckenridge R, Lovering RC.

Version 2. F1000Res. 2013 Nov 13 [revised 2014 Jan 1];2:242. doi: 10.12688/f1000research.2-242.v2. eCollection 2013.

19.

A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome.

Neary MT, Mohun TJ, Breckenridge RA.

Dis Model Mech. 2013 Mar;6(2):503-7. doi: 10.1242/dmm.010587. Epub 2012 Sep 11.

20.

Chemical labelling of active serum thioester proteins for quantification.

Holm L, Ackland GL, Edwards MR, Breckenridge RA, Sim RB, Offer J.

Immunobiology. 2012 Feb;217(2):256-64. doi: 10.1016/j.imbio.2011.07.021. Epub 2011 Jul 23.

21.

The representation of heart development in the gene ontology.

Khodiyar VK, Hill DP, Howe D, Berardini TZ, Tweedie S, Talmud PJ, Breckenridge R, Bhattarcharya S, Riley P, Scambler P, Lovering RC.

Dev Biol. 2011 Jun 1;354(1):9-17. doi: 10.1016/j.ydbio.2011.03.011. Epub 2011 Mar 17.

22.

Technology and patient safety: only part of the solution.

Breckenridge RA.

Br J Hosp Med (Lond). 2010 Oct;71(10):544-5. No abstract available.

PMID:
21085067
23.

Absence of the inhibitory G-protein Galphai2 predisposes to ventricular cardiac arrhythmia.

Zuberi Z, Nobles M, Sebastian S, Dyson A, Lim SY, Breckenridge R, Birnbaumer L, Tinker A.

Circ Arrhythm Electrophysiol. 2010 Aug;3(4):391-400. doi: 10.1161/CIRCEP.109.894329. Epub 2010 May 21.

24.

Heart failure and mouse models.

Breckenridge R.

Dis Model Mech. 2010 Mar-Apr;3(3-4):138-43. doi: 10.1242/dmm.005017. Review.

25.

A role for Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) in mammalian development.

Breckenridge RA, Kelly P, Nandi M, Vallance PJ, Ohun TJ, Leiper J.

Int J Dev Biol. 2010;54(1):215-20. doi: 10.1387/ijdb.072356rb.

26.

Overexpression of the transcription factor Hand1 causes predisposition towards arrhythmia in mice.

Breckenridge RA, Zuberi Z, Gomes J, Orford R, Dupays L, Felkin LE, Clark JE, Magee AI, Ehler E, Birks EJ, Barton PJ, Tinker A, Mohun TJ.

J Mol Cell Cardiol. 2009 Jul;47(1):133-41. doi: 10.1016/j.yjmcc.2009.04.007. Epub 2009 Apr 17.

PMID:
19376125
27.

Pan-myocardial expression of Cre recombinase throughout mouse development.

Breckenridge R, Kotecha S, Towers N, Bennett M, Mohun T.

Genesis. 2007 Mar;45(3):135-44.

PMID:
17334998
28.

Isolated left ventricular non-compaction: the case for abnormal myocardial development.

Breckenridge RA, Anderson RH, Elliott PM.

Cardiol Young. 2007 Apr;17(2):124-9. Epub 2007 Feb 26. Review.

PMID:
17319979
29.

Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart.

Risebro CA, Smart N, Dupays L, Breckenridge R, Mohun TJ, Riley PR.

Development. 2006 Nov;133(22):4595-606. Epub 2006 Oct 18.

30.

Bronchogenic squamous cell carcinoma presenting as cicatrizing conjunctivitis.

Vroman DT, Breckenridge RR, Solomon KD, Sandoval HP, Fernández de Castro LE.

Cornea. 2006 Jun;25(5):611-3.

PMID:
16783152
31.

Outflow resistance of the Baerveldt glaucoma drainage implant and modifications for early postoperative intraocular pressure control.

Breckenridge RR, Bartholomew LR, Crosson CE, Kent AR.

J Glaucoma. 2004 Oct;13(5):396-9.

PMID:
15354078
32.

A role for BMP signalling in heart looping morphogenesis in Xenopus.

Breckenridge RA, Mohun TJ, Amaya E.

Dev Biol. 2001 Apr 1;232(1):191-203.

33.

Similarities and differences in the structure-activity relationships of capsaicin and resiniferatoxin analogues.

Walpole CS, Bevan S, Bloomfield G, Breckenridge R, James IF, Ritchie T, Szallasi A, Winter J, Wrigglesworth R.

J Med Chem. 1996 Jul 19;39(15):2939-52.

PMID:
8709128
34.

A process for selecting indicators for monitoring conditions of rangeland health.

Breckenridge RP, Kepner WG, Mouat DA.

Environ Monit Assess. 1995 May;36(1):45-60. doi: 10.1007/BF00546984.

PMID:
24197675
35.

Integrated response plot designs for indicators of desertification.

Kuehl RO, Breckenridge RP, Panda M.

Environ Monit Assess. 1995 Jan;37(1-3):189-209. doi: 10.1007/BF00546889.

PMID:
24197849
36.

The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin.

Walpole CS, Bevan S, Bovermann G, Boelsterli JJ, Breckenridge R, Davies JW, Hughes GA, James I, Oberer L, Winter J, et al.

J Med Chem. 1994 Jun 24;37(13):1942-54.

PMID:
8027976
37.

Characterizing soils for hazardous waste site assessments.

Breckenridge RP, Keck JF, Williams JR.

Environ Monit Assess. 1994 Apr;30(2):113-38. doi: 10.1007/BF00545618.

PMID:
24213742
38.

1H NMR studies of echistatin in solution. Sequential resonance assignments and secondary structure.

Dalvit C, Widmer H, Bovermann G, Breckenridge R, Metternich R.

Eur J Biochem. 1991 Dec 5;202(2):315-21.

39.

Molecular recognition: models for drug design.

Breckenridge RJ.

Experientia. 1991 Dec 1;47(11-12):1148-61. Review.

PMID:
1765127
40.

Locus of control and alcohol placebo effects on performance in a driving simulator.

Breckenridge RL, Dodd MO.

Percept Mot Skills. 1991 Jun;72(3 Pt 1):751-6.

PMID:
1891310
41.

Locus of control and perceived alcohol ingestion in performance of a fine motor skill.

Breckenridge RL, Berger RS.

Psychol Rep. 1990 Feb;66(1):179-85.

PMID:
2326410
42.

The structural evolution of cobra venom cytotoxins.

Breckenridge R, Dufton MJ.

J Mol Evol. 1987;26(3):274-83.

PMID:
3129572
43.

Impact of MR imaging on clinical diagnosis and management: a prospective study.

Franken EA Jr, Berbaum KS, Dunn V, Smith WL, Ehrhardt JC, Levitz GS, Breckenridge RE.

Radiology. 1986 Nov;161(2):377-80.

PMID:
3763904
44.

Non-selective inhibition of GABA and 5-HT uptake systems in rat brain by N-n-alkyl hydroxybenzylamine and N-n-alkyl phenylethylamine derivatives.

Suckling CJ, Breckenridge RJ, Bansal SS, Williams LC, Watling KJ, Iversen LL.

Biochem Pharmacol. 1985 Dec 1;34(23):4173-7. No abstract available.

PMID:
4062986
45.

Multiphasic health testing services: can they cure medicine of its ills?

Breckenridge RL.

Pathologist. 1985 Feb;39(2):22-4.

PMID:
10270444
46.

Nosocomial meningitis due to Citrobacter diversus in neonates: new aspects of the epidemiology.

Williams WW, Mariano J, Spurrier M, Donnell HD Jr, Breckenridge RL Jr, Anderson RL, Wachsmuth IK, Thornsberry C, Graham DR, Thibeault DW, et al.

J Infect Dis. 1984 Aug;150(2):229-35.

PMID:
6470529
47.

Hospital unbundling: seize the opportunity.

Breckenridge RL.

Pathologist. 1984 Feb;38(2):99-101.

PMID:
10265483
48.

Symmetrical bone scan in a patient with acute hypercalcemia.

Licata AA, Farnand B, Gangemi R, Breckenridge R.

Arch Intern Med. 1983 Sep;143(9):1779-80.

PMID:
6615100
49.

Pathology practice under TEFRA and DRGs.

Breckenridge RL.

Pathologist. 1983 Aug;37(8):560-2.

PMID:
10310298
50.

No place for slang.

Breckenridge RL Jr.

Hum Pathol. 1983 Apr;14(4):380. No abstract available.

PMID:
6832777

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