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Social isolation, cognitive reserve, and cognition in older people with depression and anxiety.

Evans IEM, Llewellyn DJ, Matthews FE, Woods RT, Brayne C, Clare L.

Aging Ment Health. 2018 Dec 6:1-10. doi: 10.1080/13607863.2018.1506742. [Epub ahead of print]


Changes in health in the countries of the UK and 150 English Local Authority areas 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

Steel N, Ford JA, Newton JN, Davis ACJ, Vos T, Naghavi M, Glenn S, Hughes A, Dalton AM, Stockton D, Humphreys C, Dallat M, Schmidt J, Flowers J, Fox S, Abubakar I, Aldridge RW, Baker A, Brayne C, Brugha T, Capewell S, Car J, Cooper C, Ezzati M, Fitzpatrick J, Greaves F, Hay R, Hay S, Kee F, Larson HJ, Lyons RA, Majeed A, McKee M, Rawaf S, Rutter H, Saxena S, Sheikh A, Smeeth L, Viner RM, Vollset SE, Williams HC, Wolfe C, Woolf A, Murray CJL.

Lancet. 2018 Nov 3;392(10158):1647-1661. doi: 10.1016/S0140-6736(18)32207-4. Epub 2018 Oct 24.


Opportunities and challenges in public and community engagement: the connected for cognitive health in later life (CHILL) project.

Lee C, Mellor T, Dilworth-Anderson P, Young T, Brayne C, Lafortune L.

Res Involv Engagem. 2018 Nov 19;4:42. doi: 10.1186/s40900-018-0127-x. eCollection 2018.


Exploring causality of the association between smoking and Parkinson's disease.

Gallo V, Vineis P, Cancellieri M, Chiodini P, Barker RA, Brayne C, Pearce N, Vermeulen R, Panico S, Bueno-de-Mesquita B, Vanacore N, Forsgren L, Ramat S, Ardanaz E, Arriola L, Peterson J, Hansson O, Gavrila D, Sacerdote C, Sieri S, Kühn T, Katzke VA, van der Schouw YT, Kyrozis A, Masala G, Mattiello A, Perneczky R, Middleton L, Saracci R, Riboli E.

Int J Epidemiol. 2018 Nov 20. doi: 10.1093/ije/dyy230. [Epub ahead of print]


Mortality risk of loneliness in the oldest old over a 10-year follow-up.

Wang H, Leng Y, Zhao E, Fleming J, Brayne C; CC75C Study Collaboration.

Aging Ment Health. 2018 Nov 17:1-6. doi: 10.1080/13607863.2018.1510897. [Epub ahead of print]


Social Isolation and Cognitive Function in Later Life: A Systematic Review and Meta-Analysis.

Evans IEM, Martyr A, Collins R, Brayne C, Clare L.

J Alzheimers Dis. 2018 Oct 24. doi: 10.3233/JAD-180501. [Epub ahead of print]


Generalised anxiety disorder and hospital admissions: findings from a large, population cohort study.

Remes O, Wainwright N, Surtees P, Lafortune L, Khaw KT, Brayne C.

BMJ Open. 2018 Oct 27;8(10):e018539. doi: 10.1136/bmjopen-2017-018539.


Development of an Item Pool for a Needs-Based Measure of Quality of Life of Carers of a Family Member with Dementia.

Oyebode JR, Pini S, Ingleson E, Megson M, Horton M, Clare L, Al-Janabi H, Brayne C, Wright P.

Patient. 2018 Oct 12. doi: 10.1007/s40271-018-0334-4. [Epub ahead of print]


Evolution of dementia diagnosis over time (1988-2013): Evidence from French and English cohorts. Implication for secular trends analyses.

Grasset L, Matthews FE, Pérès K, Foubert-Samier A, Helmer C, Dartigues JF, Brayne C.

Alzheimers Dement (Amst). 2018 Aug 9;10:490-497. doi: 10.1016/j.dadm.2018.07.005. eCollection 2018.


Aβ and the dementia syndrome: Simple versus complex perspectives.

Hunter S, Smailagic N, Brayne C.

Eur J Clin Invest. 2018 Dec;48(12):e13025. doi: 10.1111/eci.13025. Epub 2018 Oct 4. Review.


Understanding the relationship between cognition and death: a within cohort examination of cognitive measures and mortality.

Hayat SA, Luben R, Dalzell N, Moore S, Hogervorst E, Matthews FE, Wareham N, Brayne C, Khaw KT.

Eur J Epidemiol. 2018 Nov;33(11):1049-1062. doi: 10.1007/s10654-018-0439-z. Epub 2018 Sep 10.


Autism and the right to education in the EU: Policy mapping and scoping review of the United Kingdom, France, Poland and Spain.

Roleska M, Roman-Urrestarazu A, Griffiths S, Ruigrok ANV, Holt R, van Kessel R, McColl K, Sherlaw W, Brayne C, Czabanowska K.

PLoS One. 2018 Aug 30;13(8):e0202336. doi: 10.1371/journal.pone.0202336. eCollection 2018.


Social isolation, cognitive reserve, and cognition in healthy older people.

Evans IEM, Llewellyn DJ, Matthews FE, Woods RT, Brayne C, Clare L; CFAS-Wales research team.

PLoS One. 2018 Aug 17;13(8):e0201008. doi: 10.1371/journal.pone.0201008. eCollection 2018.


Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain.

Waller R, Murphy M, Garwood CJ, Jennings L, Heath PR, Chambers A, Matthews FE, Brayne C, Ince PG, Wharton SB, Simpson JE; Cognitive Function and Ageing Neuropathology Study Group.

Glia. 2018 Nov;66(11):2316-2323. doi: 10.1002/glia.23465. Epub 2018 Aug 10.


Private health insurance in Germany and Chile: two stories of co-existence, segmentation and conflict.

Roman-Urrestarazu A, Yang JC, Ettelt S, Thalmann I, Seguel Ravest V, Brayne C.

Int J Equity Health. 2018 Aug 3;17(1):112. doi: 10.1186/s12939-018-0831-z.


The impact of dementia on service use by individuals with a comorbid health condition: a comparison of two cross-sectional analyses conducted approximately 10 years apart.

Bennett HQ, Norton S, Bunn F, Robinson L, Rait G, Goodman C, Brayne C, Matthews FE.

BMC Med. 2018 Jul 24;16(1):114. doi: 10.1186/s12916-018-1105-8.


Association of Apathy With Risk of Incident Dementia: A Systematic Review and Meta-analysis.

van Dalen JW, van Wanrooij LL, Moll van Charante EP, Brayne C, van Gool WA, Richard E.

JAMA Psychiatry. 2018 Oct 1;75(10):1012-1021. doi: 10.1001/jamapsychiatry.2018.1877.


18F-FDG PET for Prediction of Conversion to Alzheimer's Disease Dementia in People with Mild Cognitive Impairment: An Updated Systematic Review of Test Accuracy.

Smailagic N, Lafortune L, Kelly S, Hyde C, Brayne C.

J Alzheimers Dis. 2018;64(4):1175-1194. doi: 10.3233/JAD-171125.


Binge alcohol and substance use across birth cohorts and the global financial crisis in the United States.

Yang JC, Roman-Urrestarazu A, Brayne C.

PLoS One. 2018 Jun 25;13(6):e0199741. doi: 10.1371/journal.pone.0199741. eCollection 2018.


Exploring patterns of response across the lifespan: the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study.

Green E, Bennett H, Brayne C; Cam-CAN, Matthews FE.

BMC Public Health. 2018 Jun 19;18(1):760. doi: 10.1186/s12889-018-5663-7.


Is frailty a stable predictor of mortality across time? Evidence from the Cognitive Function and Ageing Studies.

Mousa A, Savva GM, Mitnitski A, Rockwood K, Jagger C, Brayne C, Matthews FE.

Age Ageing. 2018 Sep 1;47(5):721-727. doi: 10.1093/ageing/afy077.


Mitigation of disasters through community cohesion.

Brayne C.

Lancet Planet Health. 2017 Jun;1(3):e86-e87. doi: 10.1016/S2542-5196(17)30051-7. Epub 2017 Jun 9. No abstract available.


Dementia Research: Populations, Progress, Problems, and Predictions.

Hunter S, Smailagic N, Brayne C.

J Alzheimers Dis. 2018;64(s1):S119-S143. doi: 10.3233/JAD-179927.


Accuracy of death certification of dementia in population-based samples of older people: analysis over time.

Gao L, Calloway R, Zhao E, Brayne C, Matthews FE; Medical Research Council Cognitive Function and Ageing Collaboration.

Age Ageing. 2018 Apr 28. doi: 10.1093/ageing/afy068. [Epub ahead of print]


Anticholinergic drugs and risk of dementia: case-control study.

Richardson K, Fox C, Maidment I, Steel N, Loke YK, Arthur A, Myint PK, Grossi CM, Mattishent K, Bennett K, Campbell NL, Boustani M, Robinson L, Brayne C, Matthews FE, Savva GM.

BMJ. 2018 Apr 25;361:k1315. doi: 10.1136/bmj.k1315.


A strong sense of coherence associated with reduced risk of anxiety disorder among women in disadvantaged circumstances: British population study.

Remes O, Wainwright NWJ, Surtees P, Lafortune L, Khaw KT, Brayne C.

BMJ Open. 2018 Apr 23;8(4):e018501. doi: 10.1136/bmjopen-2017-018501.


Traumatic brain injury and dementia.

Brayne C.

Lancet Psychiatry. 2018 May;5(5):383-384. doi: 10.1016/S2215-0366(18)30136-6. Epub 2018 Apr 10. No abstract available.


Identifying dementia cases with routinely collected health data: A systematic review.

Wilkinson T, Ly A, Schnier C, Rannikmäe K, Bush K, Brayne C, Quinn TJ, Sudlow CLM; UK Biobank Neurodegenerative Outcomes Group and Dementias Platform UK.

Alzheimers Dement. 2018 Aug;14(8):1038-1051. doi: 10.1016/j.jalz.2018.02.016. Epub 2018 Apr 3.


Dementia case-finding in hospitals: a qualitative study exploring the views of healthcare professionals in English primary care and secondary care.

Burn AM, Fleming J, Brayne C, Fox C, Bunn F.

BMJ Open. 2018 Mar 17;8(3):e020521. doi: 10.1136/bmjopen-2017-020521.


Designing an Internet-Based Multidomain Intervention for the Prevention of Cardiovascular Disease and Cognitive Impairment in Older Adults: The HATICE Trial.

Barbera M, Mangialasche F, Jongstra S, Guillemont J, Ngandu T, Beishuizen C, Coley N, Brayne C, Andrieu S, Richard E, Soininen H, Kivipelto M; HATICE study group.

J Alzheimers Dis. 2018;62(2):649-663. doi: 10.3233/JAD-170858.


Perspectives on Communicating Biomarker-Based Assessments of Alzheimer's Disease to Cognitively Healthy Individuals.

Milne R, Bunnik E, Diaz A, Richard E, Badger S, Gove D, Georges J, Fauria K, Molinuevo JL, Wells K, Ritchie C, Brayne C.

J Alzheimers Dis. 2018;62(2):487-498. doi: 10.3233/JAD-170813.


A roadmap to advance dementia research in prevention, diagnosis, intervention, and care by 2025.

Pickett J, Bird C, Ballard C, Banerjee S, Brayne C, Cowan K, Clare L, Comas-Herrera A, Corner L, Daley S, Knapp M, Lafortune L, Livingston G, Manthorpe J, Marchant N, Moriarty J, Robinson L, van Lynden C, Windle G, Woods B, Gray K, Walton C.

Int J Geriatr Psychiatry. 2018 Jul;33(7):900-906. doi: 10.1002/gps.4868. Epub 2018 Feb 22.


Idalopirdine: another disappointment for people with dementia.

Le Couteur DG, Bateman B, Brayne C.

BMJ. 2018 Feb 21;360:k753. doi: 10.1136/bmj.k753. No abstract available.


Prevalence of dementia in mainland China, Hong Kong and Taiwan: an updated systematic review and meta-analysis.

Wu YT, Ali GC, Guerchet M, Prina AM, Chan KY, Prince M, Brayne C.

Int J Epidemiol. 2018 Feb 12. doi: 10.1093/ije/dyy007. [Epub ahead of print]


The delirium and population health informatics cohort study protocol: ascertaining the determinants and outcomes from delirium in a whole population.

Davis D, Richardson S, Hornby J, Bowden H, Hoffmann K, Weston-Clarke M, Green F, Chaturvedi N, Hughes A, Kuh D, Sampson E, Mizoguchi R, Cheah KL, Romain M, Sinha A, Jenkin R, Brayne C, MacLullich A.

BMC Geriatr. 2018 Feb 9;18(1):45. doi: 10.1186/s12877-018-0742-2.


Alcohol and older people: A systematic review of barriers, facilitators and context of drinking in older people and implications for intervention design.

Kelly S, Olanrewaju O, Cowan A, Brayne C, Lafortune L.

PLoS One. 2018 Jan 25;13(1):e0191189. doi: 10.1371/journal.pone.0191189. eCollection 2018. Review.


Interpretation of dementia diagnosis and treatment trends in the UK over time.

Brayne C.

Lancet Public Health. 2017 Mar;2(3):e128-e129. doi: 10.1016/S2468-2667(17)30030-0. Epub 2017 Feb 24. No abstract available.


Ethical Issues in the Development of Readiness Cohorts in Alzheimer's Disease Research.

Milne R, Bunnik E, Tromp K, Bemelmans S, Badger S, Gove D, Maman M, Schermer M, Truyen L, Brayne C, Richard E.

J Prev Alzheimers Dis. 2017;4(2):125-131. doi: 10.14283/jpad.2017.5.


Author response: Dementia risk in renal dysfunction: A systematic review and meta-analysis of prospective studies.

Deckers K, Camerino I, van Boxtel MPJ, Verhey FRJ, Irving K, Brayne C, Kivipelto M, Starr JM, Yaffe K, de Leeuw PW, Köhler S.

Neurology. 2017 Nov 21;89(21):2214-2215. doi: 10.1212/WNL.0000000000004664. No abstract available.


Understanding the roles of mutations in the amyloid precursor protein in Alzheimer disease.

Hunter S, Brayne C.

Mol Psychiatry. 2018 Jan;23(1):81-93. doi: 10.1038/mp.2017.218. Epub 2017 Nov 7. Review.


Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.

Chibnik LB, Wolters FJ, Bäckman K, Beiser A, Berr C, Bis JC, Boerwinkle E, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Debette S, Davis-Plourde KL, Dufouil C, Fornage M, Grasset L, Gudnason V, Hadjichrysanthou C, Helmer C, Ikram MA, Ikram MK, Kern S, Kuller LH, Launer L, Lopez OL, Matthews F, Meirelles O, Mosley T, Ower A, Psaty BM, Satizabal CL, Seshadri S, Skoog I, Stephan BCM, Tzourio C, Waziry R, Wong MM, Zettergren A, Hofman A.

Eur J Epidemiol. 2017 Oct;32(10):931-938. doi: 10.1007/s10654-017-0320-5. Epub 2017 Oct 23.


Medication usage change in older people (65+) in England over 20 years: findings from CFAS I and CFAS II.

Gao L, Maidment I, Matthews FE, Robinson L, Brayne C; Medical Research Council Cognitive Function and Ageing Study.

Age Ageing. 2018 Mar 1;47(2):220-225. doi: 10.1093/ageing/afx158.


Dementia: Dementia prevention - a call for contextualized evidence.

Lafortune L, Brayne C.

Nat Rev Neurol. 2017 Nov;13(11):703. doi: 10.1038/nrneurol.2017.150. Epub 2017 Oct 13.


Education and Successful Aging Trajectories: A Longitudinal Population-Based Latent Variable Modelling Analysis.

Cosco TD, Stephan BCM, Brayne C, Muniz G; MRC CFAS.

Can J Aging. 2017 Dec;36(4):427-434. doi: 10.1017/S0714980817000344. Epub 2017 Oct 11.


TREM2 expression in the human brain: a marker of monocyte recruitment?

Fahrenhold M, Rakic S, Classey J, Brayne C, Ince PG, Nicoll JAR, Boche D; MRC-CFAS.

Brain Pathol. 2018 Sep;28(5):595-602. doi: 10.1111/bpa.12564. Epub 2017 Oct 30.


Interventions to prevent and reduce excessive alcohol consumption in older people: a systematic review and meta-analysis.

Kelly S, Olanrewaju O, Cowan A, Brayne C, Lafortune L.

Age Ageing. 2018 Mar 1;47(2):175-184. doi: 10.1093/ageing/afx132.


Dying comfortably in very old age with or without dementia in different care settings - a representative "older old" population study.

Fleming J, Calloway R, Perrels A, Farquhar M, Barclay S, Brayne C; Cambridge City over-75s Cohort (CC75C) study.

BMC Geriatr. 2017 Oct 5;17(1):222. doi: 10.1186/s12877-017-0605-2.


Dementia: Dementia prevention - a call for contextualized evidence.

Lafortune L, Brayne C.

Nat Rev Neurol. 2017 Sep 29;13(10):579-580. doi: 10.1038/nrneurol.2017.136. No abstract available. Erratum in: Nat Rev Neurol. 2017 Oct 13;:.


Is Dementia Screening of Apparently Healthy Individuals Justified?

Chambers LW, Sivananthan S, Brayne C.

Adv Prev Med. 2017;2017:9708413. doi: 10.1155/2017/9708413. Epub 2017 Aug 8. Review.


Maximizing the Potential of Longitudinal Cohorts for Research in Neurodegenerative Diseases: A Community Perspective.

Moody CJ, Mitchell D, Kiser G, Aarsland D, Berg D, Brayne C, Costa A, Ikram MA, Mountain G, Rohrer JD, Teunissen CE, van den Berg LH, Wardlaw JM.

Front Neurosci. 2017 Aug 29;11:467. doi: 10.3389/fnins.2017.00467. eCollection 2017.

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