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Items: 37

1.

Functional screens identify coordinators of RNA molecule birth, life, and death as targetable cancer vulnerabilities.

Braun CJ, Hemann MT.

Curr Opin Genet Dev. 2019 Feb;54:105-109. doi: 10.1016/j.gde.2019.04.003. Epub 2019 May 20. Review.

PMID:
31121413
2.

The Paris pledges and the energy-water-land nexus in Latin America: Exploring implications of greenhouse gas emission reductions.

Santos Da Silva SR, Miralles-Wilhelm F, Muñoz-Castillo R, Clarke LE, Braun CJ, Delgado A, Edmonds JA, Hejazi M, Horing J, Horowitz R, Kyle P, Link R, Patel P, Turner S, McJeon HC.

PLoS One. 2019 Apr 16;14(4):e0215013. doi: 10.1371/journal.pone.0215013. eCollection 2019.

3.

Directional K+ channel insertion in a single phospholipid bilayer: Neutron reflectometry and electrophysiology in the joint exploration of a model membrane functional platform.

Rondelli V, Del Favero E, Brocca P, Fragneto G, Trapp M, Mauri L, Ciampa MG, Romani G, Braun CJ, Winterstein L, Schroeder I, Thiel G, Moroni A, Cantu' L.

Biochim Biophys Acta Gen Subj. 2018 Aug;1862(8):1742-1750. doi: 10.1016/j.bbagen.2018.05.007. Epub 2018 May 9.

4.

A Raf-Competitive K-Ras Binder Can Fail to Functionally Antagonize Signaling.

Kauke MJ, Tisdale AW, Kelly RL, Braun CJ, Hemann MT, Wittrup KD.

Mol Cancer Ther. 2018 Aug;17(8):1773-1780. doi: 10.1158/1535-7163.MCT-17-0645. Epub 2018 May 2.

5.

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.

Braun CJ, Stanciu M, Boutz PL, Patterson JC, Calligaris D, Higuchi F, Neupane R, Fenoglio S, Cahill DP, Wakimoto H, Agar NYR, Yaffe MB, Sharp PA, Hemann MT, Lees JA.

Cancer Cell. 2017 Oct 9;32(4):411-426.e11. doi: 10.1016/j.ccell.2017.08.018. Epub 2017 Sep 28.

6.

Secnidazole Treatment of Bacterial Vaginosis: A Randomized Controlled Trial.

Hillier SL, Nyirjesy P, Waldbaum AS, Schwebke JR, Morgan FG, Adetoro NA, Braun CJ.

Obstet Gynecol. 2017 Aug;130(2):379-386. doi: 10.1097/AOG.0000000000002135.

PMID:
28697102
8.

Rewiring the solid tumor epigenome for cancer therapy.

Braun CJ, Hemann MT.

Expert Rev Anticancer Ther. 2016 Sep;16(9):977-87. doi: 10.1080/14737140.2016.1212663. Epub 2016 Aug 5. Review.

PMID:
27410491
9.

Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation.

Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3892-900. doi: 10.1073/pnas.1600582113. Epub 2016 Jun 20.

10.

A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy.

Cannell IG, Merrick KA, Morandell S, Zhu CQ, Braun CJ, Grant RA, Cameron ER, Tsao MS, Hemann MT, Yaffe MB.

Cancer Cell. 2015 Dec 14;28(6):831. doi: 10.1016/j.ccell.2015.11.003. Epub 2015 Dec 14. No abstract available.

11.

A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy.

Cannell IG, Merrick KA, Morandell S, Zhu CQ, Braun CJ, Grant RA, Cameron ER, Tsao MS, Hemann MT, Yaffe MB.

Cancer Cell. 2015 Nov 9;28(5):623-637. doi: 10.1016/j.ccell.2015.09.009. Erratum in: Cancer Cell. 2015 Dec 14;28(6):831.

12.

Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide.

McFaline-Figueroa JL, Braun CJ, Stanciu M, Nagel ZD, Mazzucato P, Sangaraju D, Cerniauskas E, Barford K, Vargas A, Chen Y, Tretyakova N, Lees JA, Hemann MT, White FM, Samson LD.

Cancer Res. 2015 Aug 1;75(15):3127-38. doi: 10.1158/0008-5472.CAN-14-3616. Epub 2015 May 29.

13.

Pseudo painting/air bubble technique for planar lipid bilayers.

Braun CJ, Baer T, Moroni A, Thiel G.

J Neurosci Methods. 2014 Aug 15;233:13-7. doi: 10.1016/j.jneumeth.2014.05.031. Epub 2014 Jun 2.

PMID:
24938397
14.

Gene therapy for Wiskott-Aldrich syndrome--long-term efficacy and genotoxicity.

Braun CJ, Boztug K, Paruzynski A, Witzel M, Schwarzer A, Rothe M, Modlich U, Beier R, Göhring G, Steinemann D, Fronza R, Ball CR, Haemmerle R, Naundorf S, Kühlcke K, Rose M, Fraser C, Mathias L, Ferrari R, Abboud MR, Al-Herz W, Kondratenko I, Maródi L, Glimm H, Schlegelberger B, Schambach A, Albert MH, Schmidt M, von Kalle C, Klein C.

Sci Transl Med. 2014 Mar 12;6(227):227ra33. doi: 10.1126/scitranslmed.3007280.

15.

Sensitizing protective tumor microenvironments to antibody-mediated therapy.

Pallasch CP, Leskov I, Braun CJ, Vorholt D, Drake A, Soto-Feliciano YM, Bent EH, Schwamb J, Iliopoulou B, Kutsch N, van Rooijen N, Frenzel LP, Wendtner CM, Heukamp L, Kreuzer KA, Hallek M, Chen J, Hemann MT.

Cell. 2014 Jan 30;156(3):590-602. doi: 10.1016/j.cell.2013.12.041.

16.

Gene therapy for Wiskott-Aldrich Syndrome-Long-term reconstitution and clinical benefits, but increased risk for leukemogenesis.

Braun CJ, Witzel M, Paruzynski A, Boztug K, von Kalle C, Schmidt M, Klein C.

Rare Dis. 2014 Oct 30;2(1):e947749. doi: 10.4161/21675511.2014.947749. eCollection 2014.

17.

Viral potassium channels as a robust model system for studies of membrane-protein interaction.

Braun CJ, Lachnit C, Becker P, Henkes LM, Arrigoni C, Kast SM, Moroni A, Thiel G, Schroeder I.

Biochim Biophys Acta. 2014 Apr;1838(4):1096-103. doi: 10.1016/j.bbamem.2013.06.010. Epub 2013 Jun 17.

18.

Unraveling tumor suppressor networks with in vivo RNAi.

Braun CJ, Hemann MT.

Cell Stem Cell. 2013 Jun 6;12(6):639-41. doi: 10.1016/j.stem.2013.05.020.

19.

A role for PVRL4-driven cell-cell interactions in tumorigenesis.

Pavlova NN, Pallasch C, Elia AE, Braun CJ, Westbrook TF, Hemann M, Elledge SJ.

Elife. 2013 Apr 30;2:e00358. doi: 10.7554/eLife.00358.

20.

Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome.

Kotlarz D, Ziętara N, Uzel G, Weidemann T, Braun CJ, Diestelhorst J, Krawitz PM, Robinson PN, Hecht J, Puchałka J, Gertz EM, Schäffer AA, Lawrence MG, Kardava L, Pfeifer D, Baumann U, Pfister ED, Hanson EP, Schambach A, Jacobs R, Kreipe H, Moir S, Milner JD, Schwille P, Mundlos S, Klein C.

J Exp Med. 2013 Mar 11;210(3):433-43. doi: 10.1084/jem.20111229. Epub 2013 Feb 25.

21.

Efforts toward elucidating Thalidomide's molecular target: an expedient synthesis of the first Thalidomide biotin analogue.

Stewart SG, Braun CJ, Polomska ME, Karimi M, Abraham LJ, Stubbs KA.

Org Biomol Chem. 2010 Sep 21;8(18):4059-62. doi: 10.1039/c0ob00060d. Epub 2010 Jul 13.

PMID:
20625607
22.

New thalidomide analogues derived through Sonogashira or Suzuki reactions and their TNF expression inhibition profiles.

Stewart SG, Braun CJ, Ng SL, Polomska ME, Karimi M, Abraham LJ.

Bioorg Med Chem. 2010 Jan 15;18(2):650-62. doi: 10.1016/j.bmc.2009.12.001. Epub 2009 Dec 6.

PMID:
20034801
23.

Cell cycle arrest or apoptosis by p53: are microRNAs-192/215 and -34 making the decision?

Georges SA, Chau BN, Braun CJ, Zhang X, Dobbelstein M.

Cell Cycle. 2009 Mar 1;8(5):680-1. Epub 2009 Mar 9. No abstract available.

PMID:
19223766
24.

p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest.

Braun CJ, Zhang X, Savelyeva I, Wolff S, Moll UM, Schepeler T, Ørntoft TF, Andersen CL, Dobbelstein M.

Cancer Res. 2008 Dec 15;68(24):10094-104. doi: 10.1158/0008-5472.CAN-08-1569.

25.
26.

Regional specificity of ethanol and NMDA action in brain revealed with FOS-like immunohistochemistry and differential routes of drug administration.

Knapp DJ, Braun CJ, Duncan GE, Qian Y, Fernandes A, Crews FT, Breese GR.

Alcohol Clin Exp Res. 2001 Nov;25(11):1662-72.

PMID:
11707641
27.

Interaction of nutrition and binge ethanol treatment on brain damage and withdrawal.

Crews FT, Braun CJ, Ali R, Knapp DJ.

J Biomed Sci. 2001 Jan-Feb;8(1):134-42.

PMID:
11173987
28.

Binge ethanol consumption causes differential brain damage in young adolescent rats compared with adult rats.

Crews FT, Braun CJ, Hoplight B, Switzer RC 3rd, Knapp DJ.

Alcohol Clin Exp Res. 2000 Nov;24(11):1712-23.

PMID:
11104119
29.

Cardiovascular effects produced by R-(+)-8-hydroxy-2-(di-n-propylamino) tetralin in the preoptic area of conscious rats.

Szabó A, Bowman M, Braun CJ, Alper RH.

Eur J Pharmacol. 1996 Nov 14;315(2):187-94.

PMID:
8960883
30.

H1, H2, and H3 receptors contribute to drinking elicited by exogenous histamine and eating in rats.

Kraly FS, Keefe ME, Tribuzio RA, Kim YM, Finkell J, Braun CJ.

Pharmacol Biochem Behav. 1996 Feb;53(2):347-54.

PMID:
8808143
31.

Angiotensin AT1 and AT2 receptors contribute to drinking elicited by eating in rats.

Kraly FS, Tribuzio RA, Kim YM, Keefe ME, Braun CJ, Newman BH.

Physiol Behav. 1995 Dec;58(6):1099-109.

PMID:
8623008
32.

Spectral light extinction to characterize fast fog formation.

van Dongen ME, Smolders HJ, Braun CJ, Snoeijs CA, Willems JF.

Appl Opt. 1994 Apr 1;33(10):1980-8. doi: 10.1364/AO.33.001980.

PMID:
20885533
34.

Fungal toxins bind to the URF13 protein in maize mitochondria and Escherichia coli.

Braun CJ, Siedow JN, Levings CS 3rd.

Plant Cell. 1990 Feb;2(2):153-61.

35.

Mutations in the maize mitochondrial T-urf13 gene eliminate sensitivity to a fungal pathotoxin.

Braun CJ, Siedow JN, Williams ME, Levings CS 3rd.

Proc Natl Acad Sci U S A. 1989 Jun;86(12):4435-9.

36.

Characterization of inverted repeats from plasmid-like DNAs and the maize mitochondrial genome.

Braun CJ, Sisco PH, Sederoff RR, Levings CS 3rd.

Curr Genet. 1986;10(8):625-30. Erratum in: Curr Genet 1986;11(1):83.

PMID:
2832079
37.

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