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Items: 1 to 50 of 97

1.

SKA-31, an activator of Ca2+-activated K+ channels, improves cardiovascular function in aging.

John CM, Khaddaj Mallat R, Mishra RC, George G, Singh V, Turnbull JD, Umeshappa CS, Kendrick DJ, Kim T, Fauzi FM, Visser F, Fedak PWM, Wulff H, Braun AP.

Pharmacol Res. 2020 Jan;151:104539. doi: 10.1016/j.phrs.2019.104539. Epub 2019 Nov 7.

PMID:
31707036
2.

Lrrc55 is a novel prosurvival factor in pancreatic islets.

Makkar G, Shrivastava V, Hlavay B, Pretorius M, Kyle BD, Braun AP, Lynn FC, Huang C.

Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E794-E804. doi: 10.1152/ajpendo.00028.2019. Epub 2019 Sep 17.

PMID:
31526288
3.

Pharmacological Targeting of KCa Channels to Improve Endothelial Function in the Spontaneously Hypertensive Rat.

Khaddaj Mallat R, Mathew John C, Mishra RC, Kendrick DJ, Braun AP.

Int J Mol Sci. 2019 Jul 16;20(14). pii: E3481. doi: 10.3390/ijms20143481.

4.

Cellular and Ionic Mechanisms of Arterial Vasomotion.

Cole WC, Gordon GR, Braun AP.

Adv Exp Med Biol. 2019;1124:297-312. doi: 10.1007/978-981-13-5895-1_12. Review.

PMID:
31183832
5.

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types.

Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH 2nd, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, Collins JJ, Shalek AK, Karp JM.

BMC Biol. 2018 Jun 5;16(1):62. doi: 10.1186/s12915-018-0527-2.

6.

Alpha1 -adrenergic stimulation selectively enhances endothelium-mediated vasodilation in rat cremaster arteries.

Mishra RC, Rahman MM, Davis MJ, Wulff H, Hill MA, Braun AP.

Physiol Rep. 2018 May;6(9):e13703. doi: 10.14814/phy2.13703.

7.

SKA-31, an activator of endothelial Ca2+-activated K+ channels evokes robust vasodilation in rat mesenteric arteries.

Khaddaj-Mallat R, Mathew John C, Braun AP.

Eur J Pharmacol. 2018 Jul 15;831:60-67. doi: 10.1016/j.ejphar.2018.05.006. Epub 2018 May 9.

PMID:
29753043
8.

Pharmacologic targeting of endothelial Ca2+-activated K+ channels: A strategy to improve cardiovascular function.

Mathew John C, Khaddaj Mallat R, George G, Kim T, Mishra RC, Braun AP.

Channels (Austin). 2018 Jan 1;12(1):126-136. doi: 10.1080/19336950.2018.1454814. Review.

9.

The vascular endothelium: A regulator of arterial tone and interface for the immune system.

Khaddaj Mallat R, Mathew John C, Kendrick DJ, Braun AP.

Crit Rev Clin Lab Sci. 2017 Nov - Dec;54(7-8):458-470. doi: 10.1080/10408363.2017.1394267. Epub 2017 Oct 30. Review.

PMID:
29084470
10.

Minor Salivary Gland Carcinoma of the Oropharynx: A Population-Based Analysis of 1426 Patients.

Goel AN, Badran KW, Braun APG, Garrett AM, Long JL.

Otolaryngol Head Neck Surg. 2018 Feb;158(2):287-294. doi: 10.1177/0194599817735309. Epub 2017 Oct 3.

PMID:
28971745
11.

The augmentation of BK channel activity by nitric oxide signaling in rat cerebral arteries involves co-localized regulatory elements.

Kyle BD, Mishra RC, Braun AP.

J Cereb Blood Flow Metab. 2017 Dec;37(12):3759-3773. doi: 10.1177/0271678X17691291. Epub 2017 Feb 3.

12.
13.

Correction: Cysteine String Protein Limits Expression of the Large Conductance, Calcium-Activated K+ (BK) Channel.

Ahrendt E, Kyle B, Braun AP, Braun JE.

PLoS One. 2015 Oct 2;10(10):e0140073. doi: 10.1371/journal.pone.0140073. eCollection 2015. No abstract available.

14.

A pharmacologic activator of endothelial KCa channels increases systemic conductance and reduces arterial pressure in an anesthetized pig model.

Mishra RC, Mitchell JR, Gibbons-Kroeker C, Wulff H, Belenkie I, Tyberg JV, Braun AP.

Vascul Pharmacol. 2016 Apr;79:24-31. doi: 10.1016/j.vph.2015.07.016. Epub 2015 Aug 1.

15.

Increased Expression of the Large Conductance, Calcium-Activated K+ (BK) Channel in Adult-Onset Neuronal Ceroid Lipofuscinosis.

Donnelier J, Braun ST, Dolzhanskaya N, Ahrendt E, Braun AP, Velinov M, Braun JE.

PLoS One. 2015 Apr 23;10(4):e0125205. doi: 10.1371/journal.pone.0125205. eCollection 2015.

16.

Inhibition of Myogenic Tone in Rat Cremaster and Cerebral Arteries by SKA-31, an Activator of Endothelial KCa2.3 and KCa3.1 Channels.

Mishra RC, Wulff H, Hill MA, Braun AP.

J Cardiovasc Pharmacol. 2015 Jul;66(1):118-27. doi: 10.1097/FJC.0000000000000252.

17.
18.

A novel disease connection for TRPM2 channels.

Braun AP.

Channels (Austin). 2014;8(6):475-6. doi: 10.4161/19336950.2014.991255. No abstract available.

19.

The regulation of BK channel activity by pre- and post-translational modifications.

Kyle BD, Braun AP.

Front Physiol. 2014 Aug 22;5:316. doi: 10.3389/fphys.2014.00316. eCollection 2014. Review.

20.

Ca(V)3.2 channels and the induction of negative feedback in cerebral arteries.

Harraz OF, Abd El-Rahman RR, Bigdely-Shamloo K, Wilson SM, Brett SE, Romero M, Gonzales AL, Earley S, Vigmond EJ, Nygren A, Menon BK, Mufti RE, Watson T, Starreveld Y, Furstenhaupt T, Muellerleile PR, Kurjiaka DT, Kyle BD, Braun AP, Welsh DG.

Circ Res. 2014 Sep 12;115(7):650-61. doi: 10.1161/CIRCRESAHA.114.304056. Epub 2014 Aug 1.

21.

Large conductance Ca2+-activated K+ channel (BKCa) α-subunit splice variants in resistance arteries from rat cerebral and skeletal muscle vasculature.

Nourian Z, Li M, Leo MD, Jaggar JH, Braun AP, Hill MA.

PLoS One. 2014 Jun 12;9(6):e98863. doi: 10.1371/journal.pone.0098863. eCollection 2014.

22.

A pharmacologic activator of endothelial KCa channels enhances coronary flow in the hearts of type 2 diabetic rats.

Mishra RC, Wulff H, Cole WC, Braun AP.

J Mol Cell Cardiol. 2014 Jul;72:364-73. doi: 10.1016/j.yjmcc.2014.04.013. Epub 2014 Apr 29.

PMID:
24787473
23.
24.

Tracking allosteric propagation with HX-MS.

Braun AP, Schriemer DC.

Structure. 2014 Apr 8;22(4):512-4. doi: 10.1016/j.str.2014.03.005.

25.

Cysteine string protein limits expression of the large conductance, calcium-activated K⁺ (BK) channel.

Ahrendt E, Kyle B, Braun AP, Braun JE.

PLoS One. 2014 Jan 27;9(1):e86586. doi: 10.1371/journal.pone.0086586. eCollection 2014. Erratum in: PLoS One. 2015;10(10):e0140073.

26.
27.

The large conductance, calcium-activated K+ (BK) channel is regulated by cysteine string protein.

Kyle BD, Ahrendt E, Braun AP, Braun JE.

Sci Rep. 2013;3:2447. doi: 10.1038/srep02447.

28.
29.

CRACking the structure of Orai: new work reveals the intramolecular properties of a store-operated, calcium influx channel.

Braun AP.

Channels (Austin). 2013 Mar-Apr;7(2):71-3. doi: 10.4161/chan.24163. Epub 2013 Mar 1. No abstract available.

30.

Specific phosphorylation sites underlie the stimulation of a large conductance, Ca(2+)-activated K(+) channel by cGMP-dependent protein kinase.

Kyle BD, Hurst S, Swayze RD, Sheng J, Braun AP.

FASEB J. 2013 May;27(5):2027-38. doi: 10.1096/fj.12-223669. Epub 2013 Feb 13.

PMID:
23407708
31.

Mechanisms underlying regional differences in the Ca2+ sensitivity of BK(Ca) current in arteriolar smooth muscle.

Yang Y, Sohma Y, Nourian Z, Ella SR, Li M, Stupica A, Korthuis RJ, Davis MJ, Braun AP, Hill MA.

J Physiol. 2013 Mar 1;591(5):1277-93. doi: 10.1113/jphysiol.2012.241562. Epub 2013 Jan 7.

32.

Keeping active channels in their place: membrane phosphoinositides regulate TRPM channel activity in a compartment-selective manner.

Braun AP.

Channels (Austin). 2012 Nov-Dec;6(6):407-8. doi: 10.4161/chan.22897. Epub 2012 Nov 1.

33.

SKA-31, a novel activator of SK(Ca) and IK(Ca) channels, increases coronary flow in male and female rat hearts.

Mishra RC, Belke D, Wulff H, Braun AP.

Cardiovasc Res. 2013 Feb 1;97(2):339-48. doi: 10.1093/cvr/cvs326. Epub 2012 Oct 31.

34.

Two-pore domain potassium channels: variation on a structural theme.

Braun AP.

Channels (Austin). 2012 May-Jun;6(3):139-40. doi: 10.4161/chan.20973. Epub 2012 May 1.

35.

Structural remodeling of the N-terminus tunes TRPA1 channel activation and regulates behavioral responses in Drosophila.

Braun AP.

Channels (Austin). 2012 Jan-Feb;6(1):50-1. doi: 10.4161/chan.19351. Epub 2012 Jan 1.

PMID:
22388005
36.

Multi-tasking at the protein level: L-type calcium channels function as ionotropic and metabotropic activators of smooth muscle contraction.

Braun AP.

Channels (Austin). 2011 Nov-Dec;5(6):459-60. doi: 10.4161/chan.5.6.17996. Epub 2011 Nov 1. No abstract available.

PMID:
21993195
37.

Purinergic P2Y2 receptors mediate rapid Ca(2+) mobilization, membrane hyperpolarization and nitric oxide production in human vascular endothelial cells.

Raqeeb A, Sheng J, Ao N, Braun AP.

Cell Calcium. 2011 Apr;49(4):240-8. doi: 10.1016/j.ceca.2011.02.008. Epub 2011 Mar 16.

PMID:
21414662
38.

Structural insights into the cytoplasmic domain of a human BK channel.

Braun AP.

Channels (Austin). 2011 Jan-Feb;5(1):1-3. Epub 2011 Jan 1.

PMID:
21263232
39.

Cooperative interactions between subunits regulate gating in holo-proton conductive channels.

Braun AP.

Channels (Austin). 2010 Mar 1;4(2). [Epub ahead of print]

PMID:
21228637
40.

A new "opening" act on the BK channel stage: identification of LRRC26 as a novel BK channel accessory subunit that enhances voltage-dependent gating.

Braun AP.

Channels (Austin). 2010 Jul-Aug;4(4):249-50. doi: 10.4161/chan.4.4.13330. Epub 2010 Jul 6. No abstract available.

PMID:
21057223
41.
42.

Coordinate regulation of stretch-activated channels and myogenic tone by polycystins 1 and 2.

Braun AP.

Channels (Austin). 2010 Jan-Feb;4(1):1-2. Epub 2010 Jan 17. No abstract available.

PMID:
20368689
43.

Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signaling.

Hill MA, Yang Y, Ella SR, Davis MJ, Braun AP.

FEBS Lett. 2010 May 17;584(10):2033-42. doi: 10.1016/j.febslet.2010.02.045. Epub 2010 Feb 20. Review.

44.

Evaluation of bond strength and internal adaptation between the dental cavity and adhesives applied in one and two layers.

Soares CG, Carracho HG, Braun AP, Borges GA, Hirakata LM, Spohr AM.

Oper Dent. 2010 Jan-Feb;35(1):69-76. doi: 10.2341/09-061-L.

PMID:
20166413
45.

Convergent signaling events underlie dopamine-mediated inhibition of CaV3.2 T-type calcium channels.

Braun AP.

Channels (Austin). 2009 Nov;3(6):381-2. Epub 2009 Nov 7. No abstract available.

PMID:
20026912
46.

Single particle imaging of a mammalian BK channel: extending primary sequence to tertiary structure.

Braun AP.

Channels (Austin). 2009 Sep-Oct;3(5):299-300. No abstract available.

PMID:
19934644
47.

Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation.

Yang Y, Wu X, Gui P, Wu J, Sheng JZ, Ling S, Braun AP, Davis GE, Davis MJ.

J Biol Chem. 2010 Jan 1;285(1):131-41. doi: 10.1074/jbc.M109.033506. Epub 2009 Nov 3.

48.

Alternative splicing of TRIP8b diversifies its actions as an accessory subunit of neuronal HCN channels.

Braun AP.

Channels (Austin). 2009 Jul-Aug;3(4):217-8. Epub 2009 Jul 27. No abstract available.

PMID:
19690453
49.

Distinct post-translational modifications regulate BK channel activity: the interplay between protein palmitoylation and phosphorylation.

Braun AP.

Channels (Austin). 2009 May-Jun;3(3):144-5. Epub 2009 May 12. Review. No abstract available.

PMID:
19556862
50.

Re-evaluating membrane transport processes: new insights and appreciation of protein behavior.

Braun AP.

Channels (Austin). 2009 May-Jun;3(3):143. Epub 2009 May 11. Review. No abstract available.

PMID:
19556861

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