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Items: 1 to 50 of 198

1.

Mutations present in a low-passage Zika virus isolate result in attenuated pathogenesis in mice.

Duggal NK, McDonald EM, Weger-Lucarelli J, Hawks SA, Ritter JM, Romo H, Ebel GD, Brault AC.

Virology. 2019 Feb 7;530:19-26. doi: 10.1016/j.virol.2019.02.004. [Epub ahead of print]

PMID:
30763872
2.

Comparative fitness of West Nile virus isolated during California epidemics.

Worwa G, Hutton AA, Brault AC, Reisen WK.

PLoS Negl Trop Dis. 2019 Feb 4;13(2):e0007135. doi: 10.1371/journal.pntd.0007135. eCollection 2019 Feb.

3.

A novel role of bone morphogenetic protein 6 (BMP6) in glucose homeostasis.

Pauk M, Bordukalo-Niksic T, Brkljacic J, Paralkar VM, Brault AL, Dumic-Cule I, Borovecki F, Grgurevic L, Vukicevic S.

Acta Diabetol. 2018 Dec 11. doi: 10.1007/s00592-018-1265-1. [Epub ahead of print]

PMID:
30539233
4.

Restriction of Zika virus infection and transmission in Aedes aegypti mediated by an insect-specific flavivirus.

Romo H, Kenney JL, Blitvich BJ, Brault AC.

Emerg Microbes Infect. 2018 Nov 15;7(1):181. doi: 10.1038/s41426-018-0180-4.

5.

Chikungunya and Zika Viruses: Global Emerging Health Threats.

Blitvich BJ, Brault AC.

Am J Trop Med Hyg. 2018 Oct;99(4):1105-1106. doi: 10.4269/ajtmh.18-0613. No abstract available.

6.

Heartland Virus Epidemiology, Vector Association, and Disease Potential.

Brault AC, Savage HM, Duggal NK, Eisen RJ, Staples JE.

Viruses. 2018 Sep 14;10(9). pii: E498. doi: 10.3390/v10090498. Review.

7.

Infection of epididymal epithelial cells and leukocytes drives seminal shedding of Zika virus in a mouse model.

McDonald EM, Duggal NK, Ritter JM, Brault AC.

PLoS Negl Trop Dis. 2018 Aug 2;12(8):e0006691. doi: 10.1371/journal.pntd.0006691. eCollection 2018 Aug.

8.

Generation of a Lineage II Powassan Virus (Deer Tick Virus) cDNA Clone: Assessment of Flaviviral Genetic Determinants of Tick and Mosquito Vector Competence.

Kenney JL, Anishchenko M, Hermance M, Romo H, Chen CI, Thangamani S, Brault AC.

Vector Borne Zoonotic Dis. 2018 Jul;18(7):371-381. doi: 10.1089/vbz.2017.2224. Epub 2018 May 21.

PMID:
29782238
9.

Bunyavirus Taxonomy: Limitations and Misconceptions Associated with the Current ICTV Criteria Used for Species Demarcation.

Blitvich BJ, Beaty BJ, Blair CD, Brault AC, Dobler G, Drebot MA, Haddow AD, Kramer LD, LaBeaud AD, Monath TP, Mossel EC, Plante K, Powers AM, Tesh RB, Turell MJ, Vasilakis N, Weaver SC.

Am J Trop Med Hyg. 2018 Jul;99(1):11-16. doi: 10.4269/ajtmh.18-0038. Epub 2018 Apr 19.

PMID:
29692303
10.

Zika Virus Shedding in Semen of Symptomatic Infected Men.

Mead PS, Duggal NK, Hook SA, Delorey M, Fischer M, Olzenak McGuire D, Becksted H, Max RJ, Anishchenko M, Schwartz AM, Tzeng WP, Nelson CA, McDonald EM, Brooks JT, Brault AC, Hinckley AF.

N Engl J Med. 2018 Apr 12;378(15):1377-1385. doi: 10.1056/NEJMoa1711038.

11.

Comparative Vector Competence of North American Culex pipiens and Culex quinquefasciatus for African and European Lineage 2 West Nile Viruses.

Romo H, Papa A, Kading R, Clark R, Delorey M, Brault AC.

Am J Trop Med Hyg. 2018 Jun;98(6):1863-1869. doi: 10.4269/ajtmh.17-0935. Epub 2018 Apr 5.

PMID:
29637885
12.

Continued Need for Comprehensive Genetic and Phenotypic Characterization of Viruses: Benefits of Complementing Sequence Analyses with Functional Determinations.

Brault AC, Blitvich BJ.

Am J Trop Med Hyg. 2018 May;98(5):1213. doi: 10.4269/ajtmh.18-0128. Epub 2018 Mar 15. No abstract available.

13.

Sexual transmission of Zika virus enhances in utero transmission in a mouse model.

Duggal NK, McDonald EM, Ritter JM, Brault AC.

Sci Rep. 2018 Mar 14;8(1):4510. doi: 10.1038/s41598-018-22840-6.

14.

West Nile and St. Louis encephalitis viral genetic determinants of avian host competence.

Maharaj PD, Bosco-Lauth AM, Langevin SA, Anishchenko M, Bowen RA, Reisen WK, Brault AC.

PLoS Negl Trop Dis. 2018 Feb 15;12(2):e0006302. doi: 10.1371/journal.pntd.0006302. eCollection 2018 Feb.

15.

Modes of Transmission of Zika Virus.

Gregory CJ, Oduyebo T, Brault AC, Brooks JT, Chung KW, Hills S, Kuehnert MJ, Mead P, Meaney-Delman D, Rabe I, Staples E, Petersen LR.

J Infect Dis. 2017 Dec 16;216(suppl_10):S875-S883. doi: 10.1093/infdis/jix396.

16.

Increases in the competitive fitness of West Nile virus isolates after introduction into California.

Worwa G, Hutton AA, Frey M, Duggal NK, Brault AC, Reisen WK.

Virology. 2018 Jan 15;514:170-181. doi: 10.1016/j.virol.2017.11.017. Epub 2017 Nov 28.

17.

A Zika Vaccine Targeting NS1 Protein Protects Immunocompetent Adult Mice in a Lethal Challenge Model.

Brault AC, Domi A, McDonald EM, Talmi-Frank D, McCurley N, Basu R, Robinson HL, Hellerstein M, Duggal NK, Bowen RA, Guirakhoo F.

Sci Rep. 2017 Nov 7;7(1):14769. doi: 10.1038/s41598-017-15039-8.

18.

Lack of evidence for Zika virus transmission by Culex mosquitoes.

Roundy CM, Azar SR, Brault AC, Ebel GD, Failloux AB, Fernandez-Salas I, Kitron U, Kramer LD, Lourenço-de-Oliveira R, Osorio JE, Paploski ID, Vazquez-Prokopec GM, Ribeiro GS, Ritchie SA, Tauro LB, Vasilakis N, Weaver SC.

Emerg Microbes Infect. 2017 Oct 18;6(10):e90. doi: 10.1038/emi.2017.85. No abstract available.

19.

Pathogenesis and sexual transmission of Spondweni and Zika viruses.

McDonald EM, Duggal NK, Brault AC.

PLoS Negl Trop Dis. 2017 Oct 6;11(10):e0005990. doi: 10.1371/journal.pntd.0005990. eCollection 2017 Oct.

20.

The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.

Hall J, Ralph EC, Shanker S, Wang H, Byrnes LJ, Horst R, Wong J, Brault A, Dumlao D, Smith JF, Dakin LA, Schmitt DC, Trujillo J, Vincent F, Griffor M, Aulabaugh AE.

Protein Sci. 2017 Dec;26(12):2367-2380. doi: 10.1002/pro.3304. Epub 2017 Oct 25.

21.

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.

Hall J, Brault A, Vincent F, Weng S, Wang H, Dumlao D, Aulabaugh A, Aivazian D, Castro D, Chen M, Culp J, Dower K, Gardner J, Hawrylik S, Golenbock D, Hepworth D, Horn M, Jones L, Jones P, Latz E, Li J, Lin LL, Lin W, Lin D, Lovering F, Niljanskul N, Nistler R, Pierce B, Plotnikova O, Schmitt D, Shanker S, Smith J, Snyder W, Subashi T, Trujillo J, Tyminski E, Wang G, Wong J, Lefker B, Dakin L, Leach K.

PLoS One. 2017 Sep 21;12(9):e0184843. doi: 10.1371/journal.pone.0184843. eCollection 2017.

22.

Differential Neurovirulence of African and Asian Genotype Zika Virus Isolates in Outbred Immunocompetent Mice.

Duggal NK, Ritter JM, McDonald EM, Romo H, Guirakhoo F, Davis BS, Chang GJ, Brault AC.

Am J Trop Med Hyg. 2017 Nov;97(5):1410-1417. doi: 10.4269/ajtmh.17-0263. Epub 2017 Aug 18.

23.

Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone.

Weger-Lucarelli J, Duggal NK, Brault AC, Geiss BJ, Ebel GD.

J Vis Exp. 2017 Jun 7;(124). doi: 10.3791/55857.

24.

Transmission Incompetence of Culex quinquefasciatus and Culex pipiens pipiens from North America for Zika Virus.

Kenney JL, Romo H, Duggal NK, Tzeng WP, Burkhalter KL, Brault AC, Savage HM.

Am J Trop Med Hyg. 2017 May;96(5):1235-1240. doi: 10.4269/ajtmh.16-0865.

25.

Rapid and specific detection of Asian- and African-lineage Zika viruses.

Chotiwan N, Brewster CD, Magalhaes T, Weger-Lucarelli J, Duggal NK, Rückert C, Nguyen C, Garcia Luna SM, Fauver JR, Andre B, Gray M, Black WC 4th, Kading RC, Ebel GD, Kuan G, Balmaseda A, Jaenisch T, Marques ETA, Brault AC, Harris E, Foy BD, Quackenbush SL, Perera R, Rovnak J.

Sci Transl Med. 2017 May 3;9(388). pii: eaag0538. doi: 10.1126/scitranslmed.aag0538.

26.

Erratum for Weger-Lucarelli et al., "Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone".

Weger-Lucarelli J, Duggal NK, Bullard-Feibelman K, Veselinovic M, Romo H, Nguyen C, Rückert C, Brault AC, Bowen RA, Stenglein M, Geiss BJ, Ebel GD.

J Virol. 2017 Mar 29;91(8). pii: e00172-17. doi: 10.1128/JVI.00172-17. Print 2017 Apr 15. No abstract available.

27.

Frequent Zika Virus Sexual Transmission and Prolonged Viral RNA Shedding in an Immunodeficient Mouse Model.

Duggal NK, Ritter JM, Pestorius SE, Zaki SR, Davis BS, Chang GJ, Bowen RA, Brault AC.

Cell Rep. 2017 Feb 14;18(7):1751-1760. doi: 10.1016/j.celrep.2017.01.056.

28.

Uncertainty quantification of inflow boundary condition and proximal arterial stiffness-coupled effect on pulse wave propagation in a vascular network.

Brault A, Dumas L, Lucor D.

Int J Numer Method Biomed Eng. 2017 Oct;33(10). doi: 10.1002/cnm.2859. Epub 2017 Feb 24.

PMID:
27943622
29.

Vertebrate Host Susceptibility to Heartland Virus.

Bosco-Lauth AM, Calvert AE, Root JJ, Gidlewski T, Bird BH, Bowen RA, Muehlenbachs A, Zaki SR, Brault AC.

Emerg Infect Dis. 2016 Dec;22(12):2070-2077. doi: 10.3201/eid2212.160472.

30.

Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone.

Weger-Lucarelli J, Duggal NK, Bullard-Feibelman K, Veselinovic M, Romo H, Nguyen C, Rückert C, Brault AC, Bowen RA, Stenglein M, Geiss BJ, Ebel GD.

J Virol. 2016 Dec 16;91(1). pii: e01765-16. Print 2017 Jan 1. Erratum in: J Virol. 2017 Mar 29;91(8):.

31.

MicroRNA reduction of neuronal West Nile virus replication attenuates and affords a protective immune response in mice.

Brostoff T, Pesavento PA, Barker CM, Kenney JL, Dietrich EA, Duggal NK, Bosco-Lauth AM, Brault AC.

Vaccine. 2016 Oct 17;34(44):5366-5375. doi: 10.1016/j.vaccine.2016.08.063. Epub 2016 Sep 13.

32.

Ebola Virus Disease Diagnostics, Sierra Leone: Analysis of Real-time Reverse Transcription-Polymerase Chain Reaction Values for Clinical Blood and Oral Swab Specimens.

Erickson BR, Sealy TK, Flietstra T, Morgan L, Kargbo B, Matt-Lebby VE, Gibbons A, Chakrabarti AK, Graziano J, Presser L, Flint M, Bird BH, Brown S, Klena JD, Blau DM, Brault AC, Belser JA, Salzer JS, Schuh AJ, Lo M, Zivcec M, Priestley RA, Pyle M, Goodman C, Bearden S, Amman BR, Basile A, Bergeron É, Bowen MD, Dodd KA, Freeman MM, McMullan LK, Paddock CD, Russell BJ, Sanchez AJ, Towner JS, Wang D, Zemtsova GE, Stoddard RA, Turnsek M, Guerrero LW, Emery SL, Stovall J, Kainulainen MH, Perniciaro JL, Mijatovic-Rustempasic S, Shakirova G, Winter J, Sexton C, Liu F, Slater K, Anderson R, Andersen L, Chiang CF, Tzeng WP, Crowe SJ, Maenner MJ, Spiropoulou CF, Nichol ST, Ströher U.

J Infect Dis. 2016 Oct 15;214(suppl 3):S258-S262. Epub 2016 Aug 31.

33.

West Nile Virus Temperature Sensitivity and Avian Virulence Are Modulated by NS1-2B Polymorphisms.

Dietrich EA, Langevin SA, Huang CY, Maharaj PD, Delorey MJ, Bowen RA, Kinney RM, Brault AC.

PLoS Negl Trop Dis. 2016 Aug 22;10(8):e0004938. doi: 10.1371/journal.pntd.0004938. eCollection 2016 Aug.

34.

Php4 Is a Key Player for Iron Economy in Meiotic and Sporulating Cells.

Brault A, Rallis C, Normant V, Garant JM, Bähler J, Labbé S.

G3 (Bethesda). 2016 Oct 13;6(10):3077-3095. doi: 10.1534/g3.116.031898.

35.

Virulence and Evolution of West Nile Virus, Australia, 1960-2012.

Prow NA, Edmonds JH, Williams DT, Setoh YX, Bielefeldt-Ohmann H, Suen WW, Hobson-Peters J, van den Hurk AF, Pyke AT, Hall-Mendelin S, Northill JA, Johansen CA, Warrilow D, Wang J, Kirkland PD, Doggett S, Andrade CC, Brault AC, Khromykh AA, Hall RA.

Emerg Infect Dis. 2016 Aug;22(8):1353-62. doi: 10.3201/eid2208.151719.

36.

The Development of Small Animal Models for Zika Virus Vaccine Efficacy Testing and Pathological Assessment.

Brault AC, Bowen RA.

Am J Trop Med Hyg. 2016 Jun 1;94(6):1187-8. doi: 10.4269/ajtmh.16-0277. Epub 2016 May 2. No abstract available.

37.

Cuf2 Is a Transcriptional Co-Regulator that Interacts with Mei4 for Timely Expression of Middle-Phase Meiotic Genes.

Ioannoni R, Brault A, Labbé S.

PLoS One. 2016 Mar 17;11(3):e0151914. doi: 10.1371/journal.pone.0151914. eCollection 2016.

38.

Rhododendron groenlandicum (Labrador tea), an antidiabetic plant from the traditional pharmacopoeia of the Canadian Eastern James Bay Cree, improves renal integrity in the diet-induced obese mouse model.

Li S, Brault A, Sanchez Villavicencio M, Haddad PS.

Pharm Biol. 2016 Oct;54(10):1998-2006. doi: 10.3109/13880209.2015.1137953. Epub 2016 Feb 26.

PMID:
26916332
39.

Prognostic Indicators for Ebola Patient Survival.

Crowe SJ, Maenner MJ, Kuah S, Erickson BR, Coffee M, Knust B, Klena J, Foday J, Hertz D, Hermans V, Achar J, Caleo GM, Van Herp M, Albariño CG, Amman B, Basile AJ, Bearden S, Belser JA, Bergeron E, Blau D, Brault AC, Campbell S, Flint M, Gibbons A, Goodman C, McMullan L, Paddock C, Russell B, Salzer JS, Sanchez A, Sealy T, Wang D, Saffa G, Turay A, Nichol ST, Towner JS.

Emerg Infect Dis. 2016 Feb;22(2):217-23. doi: 10.3201/eid2202.151250.

40.

Molecular, serological and in vitro culture-based characterization of Bourbon virus, a newly described human pathogen of the genus Thogotovirus.

Lambert AJ, Velez JO, Brault AC, Calvert AE, Bell-Sakyi L, Bosco-Lauth AM, Staples JE, Kosoy OI.

J Clin Virol. 2015 Dec;73:127-132. doi: 10.1016/j.jcv.2015.10.021. Epub 2015 Oct 27.

41.

Potential for Co-Infection of a Mosquito-Specific Flavivirus, Nhumirim Virus, to Block West Nile Virus Transmission in Mosquitoes.

Goenaga S, Kenney JL, Duggal NK, Delorey M, Ebel GD, Zhang B, Levis SC, Enria DA, Brault AC.

Viruses. 2015 Nov 11;7(11):5801-12. doi: 10.3390/v7112911.

42.

Delivery of an Ebola Virus-Positive Stillborn Infant in a Rural Community Health Center, Sierra Leone, 2015.

Bower H, Grass JE, Veltus E, Brault A, Campbell S, Basile AJ, Wang D, Paddock CD, Erickson BR, Salzer JS, Belser J, Chege E, Seneca D, Saffa G, Stroeher U, Decroo T, Caleo GM.

Am J Trop Med Hyg. 2016 Feb;94(2):417-9. doi: 10.4269/ajtmh.15-0619. Epub 2015 Nov 10.

43.

Development and Characterization of Monoclonal Antibodies Directed Against the Nucleoprotein of Heartland Virus.

Calvert AE, Brault AC.

Am J Trop Med Hyg. 2015 Dec;93(6):1338-40. doi: 10.4269/ajtmh.15-0473. Epub 2015 Oct 26.

44.

Molecular basis of the regulation of iron homeostasis in fission and filamentous yeasts.

Brault A, Mourer T, Labbé S.

IUBMB Life. 2015 Nov;67(11):801-15. doi: 10.1002/iub.1441. Epub 2015 Oct 16. Review.

45.

Ebola RNA Persistence in Semen of Ebola Virus Disease Survivors - Final Report.

Deen GF, Broutet N, Xu W, Knust B, Sesay FR, McDonald SLR, Ervin E, Marrinan JE, Gaillard P, Habib N, Liu H, Liu W, Thorson AE, Yamba F, Massaquoi TA, James F, Ariyarajah A, Ross C, Bernstein K, Coursier A, Klena J, Carino M, Wurie AH, Zhang Y, Dumbuya MS, Abad N, Idriss B, Wi T, Bennett SD, Davies T, Ebrahim FK, Meites E, Naidoo D, Smith SJ, Ongpin P, Malik T, Banerjee A, Erickson BR, Liu Y, Liu Y, Xu K, Brault A, Durski KN, Winter J, Sealy T, Nichol ST, Lamunu M, Bangura J, Landoulsi S, Jambai A, Morgan O, Wu G, Liang M, Su Q, Lan Y, Hao Y, Formenty P, Ströher U, Sahr F.

N Engl J Med. 2017 Oct 12;377(15):1428-1437. doi: 10.1056/NEJMoa1511410. Epub 2015 Oct 14.

46.
47.

Ebola Virus Diagnostics: The US Centers for Disease Control and Prevention Laboratory in Sierra Leone, August 2014 to March 2015.

Flint M, Goodman CH, Bearden S, Blau DM, Amman BR, Basile AJ, Belser JA, Bergeron É, Bowen MD, Brault AC, Campbell S, Chakrabarti AK, Dodd KA, Erickson BR, Freeman MM, Gibbons A, Guerrero LW, Klena JD, Lash RR, Lo MK, McMullan LK, Momoh G, Massally JL, Goba A, Paddock CD, Priestley RA, Pyle M, Rayfield M, Russell BJ, Salzer JS, Sanchez AJ, Schuh AJ, Sealy TK, Steinau M, Stoddard RA, Taboy C, Turnsek M, Wang D, Zemtsova GE, Zivcec M, Spiropoulou CF, Ströher U, Towner JS, Nichol ST, Bird BH.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S350-8. doi: 10.1093/infdis/jiv361. Epub 2015 Jul 30.

PMID:
26232439
48.

Genotype-specific variation in West Nile virus dispersal in California.

Duggal NK, Reisen WK, Fang Y, Newman RM, Yang X, Ebel GD, Brault AC.

Virology. 2015 Nov;485:79-85. doi: 10.1016/j.virol.2015.07.004. Epub 2015 Jul 25.

49.

Susceptibility of Carrion Crows to Experimental Infection with Lineage 1 and 2 West Nile Viruses.

Lim SM, Brault AC, van Amerongen G, Bosco-Lauth AM, Romo H, Sewbalaksing VD, Bowen RA, Osterhaus AD, Koraka P, Martina BE.

Emerg Infect Dis. 2015 Aug;21(8):1357-65. doi: 10.3201/2108.140714.

50.

Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone.

Park DJ, Dudas G, Wohl S, Goba A, Whitmer SL, Andersen KG, Sealfon RS, Ladner JT, Kugelman JR, Matranga CB, Winnicki SM, Qu J, Gire SK, Gladden-Young A, Jalloh S, Nosamiefan D, Yozwiak NL, Moses LM, Jiang PP, Lin AE, Schaffner SF, Bird B, Towner J, Mamoh M, Gbakie M, Kanneh L, Kargbo D, Massally JL, Kamara FK, Konuwa E, Sellu J, Jalloh AA, Mustapha I, Foday M, Yillah M, Erickson BR, Sealy T, Blau D, Paddock C, Brault A, Amman B, Basile J, Bearden S, Belser J, Bergeron E, Campbell S, Chakrabarti A, Dodd K, Flint M, Gibbons A, Goodman C, Klena J, McMullan L, Morgan L, Russell B, Salzer J, Sanchez A, Wang D, Jungreis I, Tomkins-Tinch C, Kislyuk A, Lin MF, Chapman S, MacInnis B, Matthews A, Bochicchio J, Hensley LE, Kuhn JH, Nusbaum C, Schieffelin JS, Birren BW, Forget M, Nichol ST, Palacios GF, Ndiaye D, Happi C, Gevao SM, Vandi MA, Kargbo B, Holmes EC, Bedford T, Gnirke A, Ströher U, Rambaut A, Garry RF, Sabeti PC.

Cell. 2015 Jun 18;161(7):1516-26. doi: 10.1016/j.cell.2015.06.007.

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