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Items: 22


Benzyloxycarbonyl-proline-prolinal (ZPP): Dual complementary roles for neutrophil inhibition.

Russell DW, Hardison M, Genschmer KR, Szul T, Bratcher PE, Abdul Roda M, Xu X, Viera L, Blalock JE, Gaggar A, Noerager BD.

Biochem Biophys Res Commun. 2019 Oct 1;517(4):691-696. doi: 10.1016/j.bbrc.2019.07.111. Epub 2019 Aug 7.


Phenotyping ciliary dynamics and coordination in response to CFTR-modulators in Cystic Fibrosis respiratory epithelial cells.

Chioccioli M, Feriani L, Kotar J, Bratcher PE, Cicuta P.

Nat Commun. 2019 Apr 16;10(1):1763. doi: 10.1038/s41467-019-09798-3.


Proline-Glycine-Proline Peptides Are Critical in the Development of Smoke-Induced Emphysema.

Abdul Roda M, Xu X, Abdalla TH, Sadik M, Szul T, Bratcher PE, Viera L, Solomon GM, Wells JM, McNicholas CM, Redegeld FA, Folkerts G, Blalock JE, Gaggar A.

Am J Respir Cell Mol Biol. 2019 Apr 8. doi: 10.1165/rcmb.2018-0216OC. [Epub ahead of print]


Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung.

Genschmer KR, Russell DW, Lal C, Szul T, Bratcher PE, Noerager BD, Abdul Roda M, Xu X, Rezonzew G, Viera L, Dobosh BS, Margaroli C, Abdalla TH, King RW, McNicholas CM, Wells JM, Dransfield MT, Tirouvanziam R, Gaggar A, Blalock JE.

Cell. 2019 Jan 10;176(1-2):113-126.e15. doi: 10.1016/j.cell.2018.12.002.


Corticosteroid use and increased CXCR2 levels on leukocytes are associated with lumacaftor/ivacaftor discontinuation in cystic fibrosis patients homozygous for the F508del CFTR mutation.

Pohl K, Nichols DP, Taylor-Cousar JL, Saavedra MT, Strand MJ, Nick JA, Bratcher PE.

PLoS One. 2018 Dec 12;13(12):e0209026. doi: 10.1371/journal.pone.0209026. eCollection 2018.


Positive clinical response to ivacaftor treatment in an individual with the CFTR genotype F508del/V456A.

Bratcher PE, Hunt KC, Pickard K, Taylor-Cousar JL.

J Cyst Fibros. 2019 Mar;18(2):e9-e10. doi: 10.1016/j.jcf.2018.10.008. Epub 2018 Oct 19. No abstract available.


Neutrophils and Bacterial Coinfection: Aiding and Abetting.

Bratcher PE, Malcolm KC.

Am J Respir Cell Mol Biol. 2018 Dec;59(6):668-669. doi: 10.1165/rcmb.2018-0250ED. No abstract available.


Doxycycline improves clinical outcomes during cystic fibrosis exacerbations.

Xu X, Abdalla T, Bratcher PE, Jackson PL, Sabbatini G, Wells JM, Lou XY, Quinn R, Blalock JE, Clancy JP, Gaggar A.

Eur Respir J. 2017 Apr 5;49(4). pii: 1601102. doi: 10.1183/13993003.01102-2016. Print 2017 Apr.


HuR promotes the molecular signature and phenotype of activated microglia: Implications for amyotrophic lateral sclerosis and other neurodegenerative diseases.

Matsye P, Zheng L, Si Y, Kim S, Luo W, Crossman DK, Bratcher PE, King PH.

Glia. 2017 Jun;65(6):945-963. doi: 10.1002/glia.23137. Epub 2017 Mar 16.


Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis.

Nichols DP, Happoldt CL, Bratcher PE, Caceres SM, Chmiel JF, Malcolm KC, Saavedra MT, Saiman L, Taylor-Cousar JL, Nick JA.

J Cyst Fibros. 2017 May;16(3):358-366. doi: 10.1016/j.jcf.2016.12.003. Epub 2016 Dec 24.


The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeability.

Hahn CS, Scott DW, Xu X, Roda MA, Payne GA, Wells JM, Viera L, Winstead CJ, Bratcher P, Sparidans RW, Redegeld FA, Jackson PL, Folkerts G, Blalock JE, Patel RP, Gaggar A.

Sci Adv. 2015;1(3). pii: e1500175.


Toll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via Exosomes.

Szul T, Bratcher PE, Fraser KB, Kong M, Tirouvanziam R, Ingersoll S, Sztul E, Rangarajan S, Blalock JE, Xu X, Gaggar A.

Am J Respir Cell Mol Biol. 2016 Mar;54(3):359-69. doi: 10.1165/rcmb.2015-0108OC.


Alterations in blood leukocytes of G551D-bearing cystic fibrosis patients undergoing treatment with ivacaftor.

Bratcher PE, Rowe SM, Reeves G, Roberts T, Szul T, Harris WT, Tirouvanziam R, Gaggar A.

J Cyst Fibros. 2016 Jan;15(1):67-73. doi: 10.1016/j.jcf.2015.02.010. Epub 2015 Mar 11.


Factors influencing the measurement of plasma/serum surfactant protein D levels by ELISA.

Bratcher PE, Gaggar A.

PLoS One. 2014 Nov 3;9(11):e111466. doi: 10.1371/journal.pone.0111466. eCollection 2014.


Characterization and prevention of the adsorption of surfactant protein D to polypropylene.

Bratcher PE, Gaggar A.

PLoS One. 2013 Sep 11;8(9):e73467. doi: 10.1371/journal.pone.0073467. eCollection 2013.


MMP-9 cleaves SP-D and abrogates its innate immune functions in vitro.

Bratcher PE, Weathington NM, Nick HJ, Jackson PL, Snelgrove RJ, Gaggar A.

PLoS One. 2012;7(7):e41881. doi: 10.1371/journal.pone.0041881. Epub 2012 Jul 30.


The role of matrix metalloproteinases in cystic fibrosis lung disease.

Gaggar A, Hector A, Bratcher PE, Mall MA, Griese M, Hartl D.

Eur Respir J. 2011 Sep;38(3):721-7. doi: 10.1183/09031936.00173210. Epub 2011 Jan 13. Review.


Evolution of the capsular gene locus of Streptococcus pneumoniae serogroup 6.

Bratcher PE, Park IH, Oliver MB, Hortal M, Camilli R, Hollingshead SK, Camou T, Nahm MH.

Microbiology. 2011 Jan;157(Pt 1):189-98. doi: 10.1099/mic.0.043901-0. Epub 2010 Oct 7.


Cross-reactivity of current serogroup 6 factor sera from Statens Serum Institut with the recently described pneumococcal serotype 6d.

Bratcher PE, Nahm MH.

J Clin Microbiol. 2010 Aug;48(8):3044-5. doi: 10.1128/JCM.00839-10. Epub 2010 Jun 23. No abstract available.


Identification of natural pneumococcal isolates expressing serotype 6D by genetic, biochemical and serological characterization.

Bratcher PE, Kim KH, Kang JH, Hong JY, Nahm MH.

Microbiology. 2010 Feb;156(Pt 2):555-60. doi: 10.1099/mic.0.034116-0. Epub 2009 Nov 26.


Reduced lipopolysaccharide phosphorylation in Escherichia coli lowers the elevated ori/ter ratio in seqA mutants.

Rotman E, Bratcher P, Kuzminov A.

Mol Microbiol. 2009 Jun;72(5):1273-92. doi: 10.1111/j.1365-2958.2009.06725.x. Epub 2009 Apr 30.


Production of a unique pneumococcal capsule serotype belonging to serogroup 6.

Bratcher PE, Park IH, Hollingshead SK, Nahm MH.

Microbiology. 2009 Feb;155(Pt 2):576-83. doi: 10.1099/mic.0.024521-0.

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