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Items: 1 to 50 of 213

1.

CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells.

Mukherjee S, Tucker-Burden C, Kaissi E, Newsam A, Duggireddy H, Chau M, Zhang C, Diwedi B, Rupji M, Seby S, Kowalski J, Kong J, Read R, Brat DJ.

Cell Rep. 2018 May 8;23(6):1651-1664. doi: 10.1016/j.celrep.2018.04.016.

2.

TASI: A software tool for spatial-temporal quantification of tumor spheroid dynamics.

Hou Y, Konen J, Brat DJ, Marcus AI, Cooper LAD.

Sci Rep. 2018 May 8;8(1):7248. doi: 10.1038/s41598-018-25337-4.

3.

Predicting cancer outcomes from histology and genomics using convolutional networks.

Mobadersany P, Yousefi S, Amgad M, Gutman DA, Barnholtz-Sloan JS, Velázquez Vega JE, Brat DJ, Cooper LAD.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2970-E2979. doi: 10.1073/pnas.1717139115. Epub 2018 Mar 12.

4.

Incorporating Advances in Molecular Pathology Into Brain Tumor Diagnostics.

Velázquez Vega JE, Brat DJ.

Adv Anat Pathol. 2018 May;25(3):143-171. doi: 10.1097/PAP.0000000000000186.

PMID:
29521646
5.

A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle.

Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, Louis DN, Yong WH, Lopes MB, Rosenblum MK, Butowski N, Tihan T, Bollen AW, Phillips JJ, Wiita AP, Yeh I, Jacobson MP, Bastian BC, Perry A, Solomon DA.

Nat Commun. 2018 Feb 23;9(1):810. doi: 10.1038/s41467-018-02826-8.

6.

Practical Diagnostic Approach to the Presence of Hyphae in Neuropathology Specimens With Three Illustrative Cases.

Chavez JA, Brat DJ, Hunter SB, Velazquez Vega J, Guarner J.

Am J Clin Pathol. 2018 Jan 29;149(2):98-104. doi: 10.1093/ajcp/aqx144.

PMID:
29365030
7.

(-)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia.

Voorhees JR, Remy MT, Cintrón-Pérez CJ, El Rassi E, Khan MZ, Dutca LM, Yin TC, McDaniel LN, Williams NS, Brat DJ, Pieper AA.

Biol Psychiatry. 2017 Nov 6. pii: S0006-3223(17)32145-5. doi: 10.1016/j.biopsych.2017.10.023. [Epub ahead of print]

8.

5-Aminolevulinic Acid Guided Sampling of Glioblastoma Microenvironments Identifies Pro-Survival Signaling at Infiltrative Margins.

Ross JL, Cooper LAD, Kong J, Gutman D, Williams M, Tucker-Burden C, McCrary MR, Bouras A, Kaluzova M, Dunn WD Jr, Duong D, Hadjipanayis CG, Brat DJ.

Sci Rep. 2017 Nov 15;7(1):15593. doi: 10.1038/s41598-017-15849-w.

9.

Interactive phenotyping of large-scale histology imaging data with HistomicsML.

Nalisnik M, Amgad M, Lee S, Halani SH, Velazquez Vega JE, Brat DJ, Gutman DA, Cooper LAD.

Sci Rep. 2017 Nov 6;7(1):14588. doi: 10.1038/s41598-017-15092-3.

10.

Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models.

Yousefi S, Amrollahi F, Amgad M, Dong C, Lewis JE, Song C, Gutman DA, Halani SH, Velazquez Vega JE, Brat DJ, Cooper LAD.

Sci Rep. 2017 Sep 15;7(1):11707. doi: 10.1038/s41598-017-11817-6.

11.

Progesterone improves neurocognitive outcomes following therapeutic cranial irradiation in mice.

Yousuf S, Brat DJ, Shu HK, Wang Y, Stein DG, Atif F.

Horm Behav. 2017 Nov;96:21-30. doi: 10.1016/j.yhbeh.2017.08.004. Epub 2017 Sep 18.

PMID:
28866326
12.

Meningioma With Tyrosine-Rich Crystalloids: A Case Report and Review of the Literature.

Reinertsen E, Neill SG, Nael K, Brat DJ, Hadjipanayis CG.

Int J Surg Pathol. 2018 Apr;26(2):157-160. doi: 10.1177/1066896917727100. Epub 2017 Aug 17.

13.

Development of a Framework for Large Scale Three-Dimensional Pathology and Biomarker Imaging and Spatial Analytics.

Liang Y, Wang F, Zhang P, Saltz JH, Brat DJ, Kong J.

AMIA Jt Summits Transl Sci Proc. 2017 Jul 26;2017:75-84. eCollection 2017.

14.

DYNAMIC REGISTRATION FOR GIGAPIXEL SERIAL WHOLE SLIDE IMAGES.

Rossetti BJ, Wang F, Zhang P, Teodoro G, Brat DJ, Kong J.

Proc IEEE Int Symp Biomed Imaging. 2017 Apr;2017:424-428. doi: 10.1109/ISBI.2017.7950552. Epub 2017 Jun 19.

15.

T2-FLAIR Mismatch, an Imaging Biomarker for IDH and 1p/19q Status in Lower-grade Gliomas: A TCGA/TCIA Project.

Patel SH, Poisson LM, Brat DJ, Zhou Y, Cooper L, Snuderl M, Thomas C, Franceschi AM, Griffith B, Flanders AE, Golfinos JG, Chi AS, Jain R.

Clin Cancer Res. 2017 Oct 15;23(20):6078-6085. doi: 10.1158/1078-0432.CCR-17-0560. Epub 2017 Jul 27.

PMID:
28751449
16.

Molecular Programs Underlying Asymmetric Stem Cell Division and Their Disruption in Malignancy.

Mukherjee S, Brat DJ.

Results Probl Cell Differ. 2017;61:401-421. doi: 10.1007/978-3-319-53150-2_18. Review.

PMID:
28409315
17.

Robust Cell Segmentation for Histological Images of Glioblastoma.

Kong J, Zhang P, Liang Y, Teodoro G, Brat DJ, Wang F.

Proc IEEE Int Symp Biomed Imaging. 2016 Apr;2016:1041-1045. doi: 10.1109/ISBI.2016.7493444. Epub 2016 Jun 16.

18.

Co-amplification of phosphoinositide 3-kinase enhancer A and cyclin-dependent kinase 4 triggers glioblastoma progression.

Qi Q, Kang SS, Zhang S, Pham C, Fu H, Brat DJ, Ye K.

Oncogene. 2017 Aug 10;36(32):4562-4572. doi: 10.1038/onc.2017.67. Epub 2017 Apr 3.

19.

Chordoid glioma of the third ventricle: report of a rapidly progressive case.

Erwood AA, Velazquez-Vega JE, Neill S, Solomon DA, Butowski N, Nowlan A, Dunbar E, Brat DJ.

J Neurooncol. 2017 May;132(3):487-495. doi: 10.1007/s11060-017-2399-7. Epub 2017 Mar 18.

PMID:
28315998
20.

Genomic Analysis in the Practice of Surgical Neuropathology: The Emory Experience.

Neill SG, Saxe DF, Rossi MR, Schniederjan MJ, Brat DJ.

Arch Pathol Lab Med. 2017 Mar;141(3):355-365. doi: 10.5858/arpa.2016-0276-SAI. Review.

PMID:
28234572
21.

TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3.

Zhang C, Mukherjee S, Tucker-Burden C, Ross JL, Chau MJ, Kong J, Brat DJ.

Mol Oncol. 2017 Mar;11(3):280-294. doi: 10.1002/1878-0261.12034. Epub 2017 Feb 15.

22.

cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification.

Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Gregory Cairncross J, Pfister SM, Rutkowski S, Weller M, Wick W, von Deimling A.

Brain Pathol. 2017 Nov;27(6):851-852. doi: 10.1111/bpa.12457. Epub 2016 Dec 20. No abstract available.

PMID:
27997995
23.

Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy.

Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Cairncross JG, Pfister SM, Rutkowski S, Weller M, Wick W, von Deimling A.

Acta Neuropathol. 2017 Jan;133(1):1-3. doi: 10.1007/s00401-016-1646-x. No abstract available.

24.

Completeness of required site-specific factors for brain and CNS tumors in the Surveillance, Epidemiology and End Results (SEER) 18 database (2004-2012, varying).

Ostrom QT, Gittleman H, Kruchko C, Louis DN, Brat DJ, Gilbert MR, Petkov VI, Barnholtz-Sloan JS.

J Neurooncol. 2016 Oct;130(1):31-42. Epub 2016 Jul 14.

25.

EGFR and C/EBP-β oncogenic signaling is bidirectional in human glioma and varies with the C/EBP-β isoform.

Selagea L, Mishra A, Anand M, Ross J, Tucker-Burden C, Kong J, Brat DJ.

FASEB J. 2016 Dec;30(12):4098-4108. Epub 2016 Aug 29.

26.

Defining neoplastic diseases differently: An emerging paradigm from The Cancer Genome Atlas lower-grade gliomas project.

Halani SH, Brat DJ.

Mol Cell Oncol. 2015 Jul 29;3(2):e1074333. doi: 10.1080/23723556.2015.1074333. eCollection 2016 Mar.

27.

TNFRSF10C copy number variation is associated with metastatic colorectal cancer.

Tanenbaum DG, Hall WA, Colbert LE, Bastien AJ, Brat DJ, Kong J, Kim S, Dwivedi B, Kowalski J, Landry JC, Yu DS.

J Gastrointest Oncol. 2016 Jun;7(3):306-14. doi: 10.21037/jgo.2015.11.04.

28.

The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons.

Lee AS, De Jesús-Cortés H, Kabir ZD, Knobbe W, Orr M, Burgdorf C, Huntington P, McDaniel L, Britt JK, Hoffmann F, Brat DJ, Rajadhyaksha AM, Pieper AA.

eNeuro. 2016 Mar 31;3(2). pii: ENEURO.0006-16.2016. doi: 10.1523/ENEURO.0006-16.2016. eCollection 2016 Mar-Apr.

29.

Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study.

Jakacki RI, Cohen KJ, Buxton A, Krailo MD, Burger PC, Rosenblum MK, Brat DJ, Hamilton RL, Eckel SP, Zhou T, Lavey RS, Pollack IF.

Neuro Oncol. 2016 Oct;18(10):1442-50. doi: 10.1093/neuonc/now038. Epub 2016 Mar 22.

30.

Drosophila Brat and Human Ortholog TRIM3 Maintain Stem Cell Equilibrium and Suppress Brain Tumorigenesis by Attenuating Notch Nuclear Transport.

Mukherjee S, Tucker-Burden C, Zhang C, Moberg K, Read R, Hadjipanayis C, Brat DJ.

Cancer Res. 2016 Apr 15;76(8):2443-52. doi: 10.1158/0008-5472.CAN-15-2299. Epub 2016 Feb 18.

31.

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.

Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, Rao AA, Grifford M, Cherniack AD, Zhang H, Poisson L, Carlotti CG Jr, Tirapelli DP, Rao A, Mikkelsen T, Lau CC, Yung WK, Rabadan R, Huse J, Brat DJ, Lehman NL, Barnholtz-Sloan JS, Zheng S, Hess K, Rao G, Meyerson M, Beroukhim R, Cooper L, Akbani R, Wrensch M, Haussler D, Aldape KD, Laird PW, Gutmann DH; TCGA Research Network, Noushmehr H, Iavarone A, Verhaak RG.

Cell. 2016 Jan 28;164(3):550-63. doi: 10.1016/j.cell.2015.12.028.

32.

Genomic profiling of lower-grade gliomas uncovers cohesive disease groups: implications for diagnosis and treatment.

Zhang CM, Brat DJ.

Chin J Cancer. 2016 Jan 12;35:12. doi: 10.1186/s40880-015-0071-1.

33.

Farewell to GBM-O: Genomic and transcriptomic profiling of glioblastoma with oligodendroglioma component reveals distinct molecular subgroups.

Hinrichs BH, Newman S, Appin CL, Dunn W, Cooper L, Pauly R, Kowalski J, Rossi MR, Brat DJ.

Acta Neuropathol Commun. 2016 Jan 13;4:4. doi: 10.1186/s40478-015-0270-7.

34.

Assessing the Effects of Software Platforms on Volumetric Segmentation of Glioblastoma.

Dunn WD Jr, Aerts HJWL, Cooper LA, Holder CA, Hwang SN, Jaffe CC, Brat DJ, Jain R, Flanders AE, Zinn PO, Colen RR, Gutman DA.

J Neuroimaging Psychiatry Neurol. 2016;1(2):64-72. doi: 10.17756/jnpn.2016-008. Epub 2016 Jul 20.

35.

Management of patients with recurrence of diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline.

Nahed BV, Redjal N, Brat DJ, Chi AS, Oh K, Batchelor TT, Ryken TC, Kalkanis SN, Olson JJ.

J Neurooncol. 2015 Dec;125(3):609-30. doi: 10.1007/s11060-015-1910-2. Epub 2015 Nov 3. Review.

PMID:
26530264
36.

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.

Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J.

Nat Cell Biol. 2015 Nov;17(11):1484-96. doi: 10.1038/ncb3255. Epub 2015 Oct 19. Review.

37.

AUTOMATED CELL SEGMENTATION WITH 3D FLUORESCENCE MICROSCOPY IMAGES.

Kong J, Wang F, Teodoro G, Liang Y, Zhu Y, Tucker-Burden C, Brat DJ.

Proc IEEE Int Symp Biomed Imaging. 2015 Apr;2015:1212-1215.

38.

Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.

Wang J, Wegener JE, Huang TW, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J, Starwalt R, McDaniel L, Ward CS, Parra D, Newcomb B, Lao U, Nourigat C, Flowers DA, Cullen S, Jorstad NL, Yang Y, Glaskova L, Vigneau S, Kozlitina J, Yetman MJ, Jankowsky JL, Reichardt SD, Reichardt HM, Gärtner J, Bartolomei MS, Fang M, Loeb K, Keene CD, Bernstein I, Goodell M, Brat DJ, Huppke P, Neul JL, Bedalov A, Pieper AA.

Nature. 2015 Sep 24;525(7570):552. doi: 10.1038/nature14671. Epub 2015 Jul 15. No abstract available.

PMID:
26176914
39.

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Sabedot TS, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T Jr, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J, Gehlenborg N, Haussler D, Heiman DI, Iype L, Jacobsen A, Ju Z, Katzman S, Kim H, Knijnenburg T, Kreisberg RB, Lawrence MS, Lee W, Leinonen K, Lin P, Ling S, Liu W, Liu Y, Liu Y, Lu Y, Mills G, Ng S, Noble MS, Paull E, Rao A, Reynolds S, Saksena G, Sanborn Z, Sander C, Schultz N, Senbabaoglu Y, Shen R, Shmulevich I, Sinha R, Stuart J, Sumer SO, Sun Y, Tasman N, Taylor BS, Voet D, Weinhold N, Weinstein JN, Yang D, Yoshihara K, Zheng S, Zhang W, Zou L, Abel T, Sadeghi S, Cohen ML, Eschbacher J, Hattab EM, Raghunathan A, Schniederjan MJ, Aziz D, Barnett G, Barrett W, Bigner DD, Boice L, Brewer C, Calatozzolo C, Campos B, Carlotti CG Jr, Chan TA, Cuppini L, Curley E, Cuzzubbo S, Devine K, DiMeco F, Duell R, Elder JB, Fehrenbach A, Finocchiaro G, Friedman W, Fulop J, Gardner J, Hermes B, Herold-Mende C, Jungk C, Kendler A, Lehman NL, Lipp E, Liu O, Mandt R, McGraw M, Mclendon R, McPherson C, Neder L, Nguyen P, Noss A, Nunziata R, Ostrom QT, Palmer C, Perin A, Pollo B, Potapov A, Potapova O, Rathmell WK, Rotin D, Scarpace L, Schilero C, Senecal K, Shimmel K, Shurkhay V, Sifri S, Singh R, Sloan AE, Smolenski K, Staugaitis SM, Steele R, Thorne L, Tirapelli DP, Unterberg A, Vallurupalli M, Wang Y, Warnick R, Williams F, Wolinsky Y, Bell S, Rosenberg M, Stewart C, Huang F, Grimsby JL, Radenbaugh AJ, Zhang J.

N Engl J Med. 2015 Jun 25;372(26):2481-98. doi: 10.1056/NEJMoa1402121. Epub 2015 Jun 10.

40.

Biomarker-driven diagnosis of diffuse gliomas.

Appin CL, Brat DJ.

Mol Aspects Med. 2015 Nov;45:87-96. doi: 10.1016/j.mam.2015.05.002. Epub 2015 May 21. Review.

PMID:
26004297
41.

Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity.

Zhang S, Qi Q, Chan CB, Zhou W, Chen J, Luo HR, Appin C, Brat DJ, Ye K.

Cell Death Differ. 2016 Jan;23(1):52-63. doi: 10.1038/cdd.2015.66. Epub 2015 May 22.

42.

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.

Wang J, Wegener JE, Huang TW, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J, Starwalt R, McDaniel L, Ward CS, Parra D, Newcomb B, Lao U, Nourigat C, Flowers DA, Cullen S, Jorstad NL, Yang Y, Glaskova L, Vingeau S, Kozlitina J, Yetman MJ, Jankowsky JL, Reichardt SD, Reichardt HM, Gärtner J, Bartolomei MS, Fang M, Loeb K, Keene CD, Bernstein I, Goodell M, Brat DJ, Huppke P, Neul JL, Bedalov A, Pieper AA.

Nature. 2015 May 21;521(7552):E1-4. doi: 10.1038/nature14444. No abstract available. Erratum in: Nature. 2015 Sep 24;525(7570):552. Vigneau, Sebastian [Corrected to Vingeau, Sébastien].

43.

Bilateral optic neuropathy after erythematous rash. Bilateral anterior optic neuropathy due to RMSF.

Nazarian SM, Shaon KY, Schwankhaus JD, Chacko JG, Hudgins PA, Brat DJ.

J Neuroophthalmol. 2015 Jun;35(2):201-4. doi: 10.1097/WNO.0000000000000261. No abstract available.

PMID:
25985435
44.

Completeness and concordancy of WHO grade assignment for brain and central nervous system tumors in the United States, 2004-2011.

Lym RL, Ostrom QT, Kruchko C, Couce M, Brat DJ, Louis DN, Barnholtz-Sloan JS.

J Neurooncol. 2015 May;123(1):43-51. doi: 10.1007/s11060-015-1775-4. Epub 2015 Apr 12.

45.

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution.

Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, Laird PW, Weinstein JN, Lander ES, Gabriel S, Getz G, Meyerson M, Chin L, Barnholtz-Sloan JS, Verhaak RG.

Genome Res. 2015 Mar;25(3):316-27. doi: 10.1101/gr.180612.114. Epub 2015 Feb 3.

46.

Template for Reporting Results of Biomarker Testing of Specimens From Patients With Tumors of the Central Nervous System.

Brat DJ, Cagle PT, Dillon DA, Hattab EM, McLendon RE, Miller MA, Buckner JC; Members of the Cancer Biomarker Reporting Committee, College of American Pathologists.

Arch Pathol Lab Med. 2015 Sep;139(9):1087-93. doi: 10.5858/arpa.2014-0588-CP. Epub 2015 Feb 2. No abstract available.

PMID:
25642959
47.

Novel genotype-phenotype associations in human cancers enabled by advanced molecular platforms and computational analysis of whole slide images.

Cooper LA, Kong J, Gutman DA, Dunn WD, Nalisnik M, Brat DJ.

Lab Invest. 2015 Apr;95(4):366-76. doi: 10.1038/labinvest.2014.153. Epub 2015 Jan 19. Review.

48.

Mutational landscape of gastric adenocarcinoma in Chinese: implications for prognosis and therapy.

Chen K, Yang D, Li X, Sun B, Song F, Cao W, Brat DJ, Gao Z, Li H, Liang H, Zhao Y, Zheng H, Li M, Buckner J, Patterson SD, Ye X, Reinhard C, Bhathena A, Joshi D, Mischel PS, Croce CM, Wang YM, Raghavakaimal S, Li H, Lu X, Pan Y, Chang H, Ba S, Luo L, Cavenee WK, Zhang W, Hao X.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1107-12. doi: 10.1073/pnas.1422640112. Epub 2015 Jan 12.

49.

Tumor angiogenesis therapy using targeted delivery of Paclitaxel to the vasculature of breast cancer metastases.

Zhu S, Kisiel W, Lu YJ, Petersen LC, Ndungu JM, Moore TW, Parker ET, Sun A, Liotta DC, El-Rayes BF, Brat DJ, Snyder JP, Shoji M.

J Drug Deliv. 2014;2014:865732. doi: 10.1155/2014/865732. Epub 2014 Dec 7.

50.

Analysis of graft survival in a trial of stem cell transplant in ALS.

Tadesse T, Gearing M, Senitzer D, Saxe D, Brat DJ, Bray R, Gebel H, Hill C, Boulis N, Riley J, Feldman E, Johe K, Hazel T, Polak M, Bordeau J, Federici T, Glass JD.

Ann Clin Transl Neurol. 2014 Nov;1(11):900-8. doi: 10.1002/acn3.134. Epub 2014 Oct 22.

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