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Items: 1 to 50 of 307

1.

Domain formation and permeabilization induced by the saponin α-hederin and its aglycone hederagenin in a cholesterol-containing bilayer.

Lorent J, Lins L, Domenech Ò, Quetin-Leclercq J, Brasseur R, Mingeot-Leclercq MP.

Langmuir. 2014 Apr 29;30(16):4556-69. doi: 10.1021/la4049902. Epub 2014 Apr 14.

PMID:
24690040
2.

A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation.

Coyan FC, Abderemane-Ali F, Amarouch MY, Piron J, Mordel J, Nicolas CS, Steenman M, Mérot J, Marionneau C, Thomas A, Brasseur R, Baró I, Loussouarn G.

PLoS One. 2014 Mar 28;9(3):e93255. doi: 10.1371/journal.pone.0093255. eCollection 2014.

3.

SAHBNET, an accessible surface-based elastic network: an application to membrane protein.

Dony N, Crowet JM, Joris B, Brasseur R, Lins L.

Int J Mol Sci. 2013 May 30;14(6):11510-26. doi: 10.3390/ijms140611510.

4.

Effects of surfactin on membrane models displaying lipid phase separation.

Deleu M, Lorent J, Lins L, Brasseur R, Braun N, El Kirat K, Nylander T, Dufrêne YF, Mingeot-Leclercq MP.

Biochim Biophys Acta. 2013 Feb;1828(2):801-15. doi: 10.1016/j.bbamem.2012.11.007. Epub 2012 Nov 14.

5.

Multi-scale simulation of the simian immunodeficiency virus fusion peptide.

Crowet JM, Parton DL, Hall BA, Steinhauer S, Brasseur R, Lins L, Sansom MS.

J Phys Chem B. 2012 Nov 26;116(46):13713-21. doi: 10.1021/jp3027385. Epub 2012 Nov 9.

PMID:
23094791
6.

Modeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo.

Crowet JM, Lins L, Deshayes S, Divita G, Morris M, Brasseur R, Thomas A.

Biochim Biophys Acta. 2013 Feb;1828(2):499-509. doi: 10.1016/j.bbamem.2012.09.006. Epub 2012 Sep 19.

7.

Self-assembling peptide-based nanoparticles for siRNA delivery in primary cell lines.

Deshayes S, Konate K, Rydström A, Crombez L, Godefroy C, Milhiet PE, Thomas A, Brasseur R, Aldrian G, Heitz F, Muñoz-Morris MA, Devoisselle JM, Divita G.

Small. 2012 Jul 23;8(14):2184-8. doi: 10.1002/smll.201102413. Epub 2012 Apr 18. No abstract available.

PMID:
22514050
8.

In silico predictions of 3D structures of linear and cyclic peptides with natural and non-proteinogenic residues.

Beaufays J, Lins L, Thomas A, Brasseur R.

J Pept Sci. 2012 Jan;18(1):17-24. doi: 10.1002/psc.1410. Epub 2011 Oct 27.

PMID:
22033979
9.

Monolayer properties of uronic acid bicatenary derivatives at the air-water interface: effect of hydroxyl group stereochemistry evidenced by experimental and computational approaches.

Razafindralambo H, Richel A, Wathelet B, Blecker C, Wathelet JP, Brasseur R, Lins L, Miñones J Jr, Paquot M.

Phys Chem Chem Phys. 2011 Sep 7;13(33):15291-8. doi: 10.1039/c1cp21365b. Epub 2011 Jul 22.

PMID:
21779589
10.
11.

The Pseudomonas aeruginosa membranes: a target for a new amphiphilic aminoglycoside derivative?

Ouberai M, El Garch F, Bussiere A, Riou M, Alsteens D, Lins L, Baussanne I, Dufrêne YF, Brasseur R, Decout JL, Mingeot-Leclercq MP.

Biochim Biophys Acta. 2011 Jun;1808(6):1716-27. doi: 10.1016/j.bbamem.2011.01.014. Epub 2011 Feb 1.

12.

Happy birthday cell penetrating peptides: already 20 years.

Brasseur R, Divita G.

Biochim Biophys Acta. 2010 Dec;1798(12):2177-81. doi: 10.1016/j.bbamem.2010.09.001. Epub 2010 Sep 6.

13.

The role of proline in the membrane re-entrant helix of caveolin-1.

Aoki S, Thomas A, Decaffmeyer M, Brasseur R, Epand RM.

J Biol Chem. 2010 Oct 22;285(43):33371-80. doi: 10.1074/jbc.M110.153569. Epub 2010 Aug 20.

14.

Acylated and unacylated ghrelin binding to membranes and to ghrelin receptor: towards a better understanding of the underlying mechanisms.

Staes E, Absil PA, Lins L, Brasseur R, Deleu M, Lecouturier N, Fievez V, Rieux Ad, Mingeot-Leclercq MP, Raussens V, Préat V.

Biochim Biophys Acta. 2010 Nov;1798(11):2102-13. doi: 10.1016/j.bbamem.2010.07.002. Epub 2010 Jul 13.

15.

Insight into the cellular uptake mechanism of a secondary amphipathic cell-penetrating peptide for siRNA delivery.

Konate K, Crombez L, Deshayes S, Decaffmeyer M, Thomas A, Brasseur R, Aldrian G, Heitz F, Divita G.

Biochemistry. 2010 Apr 27;49(16):3393-402. doi: 10.1021/bi901791x.

PMID:
20302329
16.

Cholesterol interaction with proteins that partition into membrane domains: an overview.

Epand RM, Thomas A, Brasseur R, Epand RF.

Subcell Biochem. 2010;51:253-78. doi: 10.1007/978-90-481-8622-8_9. Review.

PMID:
20213547
17.

Realistic modeling approaches of structure-function properties of CPPs in non-covalent complexes.

Thomas A, Lins L, Divita G, Brasseur R.

Biochim Biophys Acta. 2010 Dec;1798(12):2217-22. doi: 10.1016/j.bbamem.2010.02.020. Epub 2010 Feb 23. Review.

18.

Standardized evaluation of protein stability.

Thomas A, Joris B, Brasseur R.

Biochim Biophys Acta. 2010 Jun;1804(6):1265-71. doi: 10.1016/j.bbapap.2010.02.008. Epub 2010 Feb 20. Review.

PMID:
20176144
19.

Edgetic perturbation models of human inherited disorders.

Zhong Q, Simonis N, Li QR, Charloteaux B, Heuze F, Klitgord N, Tam S, Yu H, Venkatesan K, Mou D, Swearingen V, Yildirim MA, Yan H, Dricot A, Szeto D, Lin C, Hao T, Fan C, Milstein S, Dupuy D, Brasseur R, Hill DE, Cusick ME, Vidal M.

Mol Syst Biol. 2009;5:321. doi: 10.1038/msb.2009.80. Epub 2009 Nov 3.

20.

Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX.

Hulikova A, Zatovicova M, Svastova E, Ditte P, Brasseur R, Kettmann R, Supuran CT, Kopacek J, Pastorek J, Pastorekova S.

FEBS Lett. 2009 Nov 19;583(22):3563-8. doi: 10.1016/j.febslet.2009.10.060. Epub 2009 Oct 25.

21.

'Edgetic' perturbation of a C. elegans BCL2 ortholog.

Dreze M, Charloteaux B, Milstein S, Vidalain PO, Yildirim MA, Zhong Q, Svrzikapa N, Romero V, Laloux G, Brasseur R, Vandenhaute J, Boxem M, Cusick ME, Hill DE, Vidal M.

Nat Methods. 2009 Nov;6(11):843-9. doi: 10.1038/nmeth.1394. Epub 2009 Oct 25. Erratum in: Nat Methods. 2009 Dec;6(12):935.

22.

Study of the specific lipid binding properties of Abeta 11-22 fragment at endosomal pH.

Ravault S, Flore C, Saurel O, Milon A, Brasseur R, Lins L.

Langmuir. 2009 Sep 15;25(18):10948-53. doi: 10.1021/la901544g.

PMID:
19735146
23.

Structural features conferring dual geranyl/farnesyl diphosphate synthase activity to an aphid prenyltransferase.

Vandermoten S, Santini S, Haubruge E, Heuze F, Francis F, Brasseur R, Cusson M, Charloteaux B.

Insect Biochem Mol Biol. 2009 Oct;39(10):707-16. doi: 10.1016/j.ibmb.2009.08.007. Epub 2009 Aug 29.

24.

The "Tilted Peptide Theory" links membrane insertion properties and fusogenicity of viral fusion peptides.

Charloteaux B, Lorin A, Brasseur R, Lins L.

Protein Pept Lett. 2009;16(7):718-25. Review.

PMID:
19601900
25.

Study of Thermomyces lanuginosa lipase in the presence of tributyrylglycerol and water.

Santini S, Crowet JM, Thomas A, Paquot M, Vandenbol M, Thonart P, Wathelet JP, Blecker C, Lognay G, Brasseur R, Lins L, Charloteaux B.

Biophys J. 2009 Jun 17;96(12):4814-25. doi: 10.1016/j.bpj.2009.03.040.

26.

Impacts of the carbonyl group location of ester bond on interfacial properties of sugar-based surfactants: experimental and computational evidences.

Razafindralambo H, Blecker C, Mezdour S, Deroanne C, Crowet JM, Brasseur R, Lins L, Paquot M.

J Phys Chem B. 2009 Jul 2;113(26):8872-7. doi: 10.1021/jp903187f.

PMID:
19518052
27.

Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus.

Prevot PP, Beschin A, Lins L, Beaufays J, Grosjean A, Bruys L, Adam B, Brossard M, Brasseur R, Zouaoui Boudjeltia K, Vanhamme L, Godfroid E.

FEBS J. 2009 Jun;276(12):3235-46. doi: 10.1111/j.1742-4658.2009.07038.x. Epub 2009 Apr 29.

28.

PepLook: an innovative in silico tool for determination of structure, polymorphism and stability of peptides.

Thomas A, Deshayes S, Decaffmeyer M, Van Eyck MH, Charloteaux BB, Brasseur R.

Adv Exp Med Biol. 2009;611:459-60. No abstract available.

PMID:
19400265
29.

Determination of the minimal fusion peptide of HIV, SIV and BLV fusion glycoproteins.

Lorin A, Charloteaux B, Lins L, Stroobant V, Brasseur R.

Adv Exp Med Biol. 2009;611:387-8. No abstract available.

PMID:
19400236
30.

Genomic location of the bovine growth hormone secretagogue receptor (GHSR) gene and investigation of genetic polymorphism.

Colinet FG, Vanderick S, Charloteaux B, Eggen A, Gengler N, Renaville B, Brasseur R, Portetelle D, Renaville R.

Anim Biotechnol. 2009;20(1):28-33. doi: 10.1080/10495390802602926.

31.

Ixodes ricinus tick lipocalins: identification, cloning, phylogenetic analysis and biochemical characterization.

Beaufays J, Adam B, Decrem Y, Prévôt PP, Santini S, Brasseur R, Brossard M, Lins L, Vanhamme L, Godfroid E.

PLoS One. 2008;3(12):e3941. doi: 10.1371/journal.pone.0003941. Epub 2008 Dec 19.

32.

Ir-LBP, an ixodes ricinus tick salivary LTB4-binding lipocalin, interferes with host neutrophil function.

Beaufays J, Adam B, Menten-Dedoyart C, Fievez L, Grosjean A, Decrem Y, Prévôt PP, Santini S, Brasseur R, Brossard M, Vanhaeverbeek M, Bureau F, Heinen E, Lins L, Vanhamme L, Godfroid E.

PLoS One. 2008;3(12):e3987. doi: 10.1371/journal.pone.0003987. Epub 2008 Dec 19.

33.

A new potent secondary amphipathic cell-penetrating peptide for siRNA delivery into mammalian cells.

Crombez L, Aldrian-Herrada G, Konate K, Nguyen QN, McMaster GK, Brasseur R, Heitz F, Divita G.

Mol Ther. 2009 Jan;17(1):95-103. doi: 10.1038/mt.2008.215. Epub 2008 Oct 28.

34.

Large changes in the CRAC segment of gp41 of HIV do not destroy fusion activity if the segment interacts with cholesterol.

Vishwanathan SA, Thomas A, Brasseur R, Epand RF, Hunter E, Epand RM.

Biochemistry. 2008 Nov 11;47(45):11869-76. doi: 10.1021/bi8014828. Epub 2008 Oct 21.

35.

Atomic force microscopy of supported lipid bilayers.

Mingeot-Leclercq MP, Deleu M, Brasseur R, Dufrêne YF.

Nat Protoc. 2008;3(10):1654-9. doi: 10.1038/nprot.2008.149.

PMID:
18833202
36.

Interactions of ciprofloxacin with DPPC and DPPG: fluorescence anisotropy, ATR-FTIR and 31P NMR spectroscopies and conformational analysis.

Bensikaddour H, Snoussi K, Lins L, Van Bambeke F, Tulkens PM, Brasseur R, Goormaghtigh E, Mingeot-Leclercq MP.

Biochim Biophys Acta. 2008 Nov;1778(11):2535-43. doi: 10.1016/j.bbamem.2008.08.015. Epub 2008 Sep 6.

37.

Determination of the topology of the hydrophobic segment of mammalian diacylglycerol kinase epsilon in a cell membrane and its relationship to predictions from modeling.

Decaffmeyer M, Shulga YV, Dicu AO, Thomas A, Truant R, Topham MK, Brasseur R, Epand RM.

J Mol Biol. 2008 Nov 21;383(4):797-809. doi: 10.1016/j.jmb.2008.08.076. Epub 2008 Sep 6.

PMID:
18801368
38.

Computational study of colipase interaction with lipid droplets and bile salt micelles.

Kerfelec B, Allouche M, Colin D, Van Eyck MH, Brasseur R, Thomas A.

Proteins. 2008 Dec;73(4):828-38. doi: 10.1002/prot.22109.

PMID:
18506778
39.

Relationships between the orientation and the structural properties of peptides and their membrane interactions.

Lins L, Decaffmeyer M, Thomas A, Brasseur R.

Biochim Biophys Acta. 2008 Jul-Aug;1778(7-8):1537-44. doi: 10.1016/j.bbamem.2008.04.006. Epub 2008 Apr 25. Review.

40.

Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity.

Vandermoten S, Charloteaux B, Santini S, Sen SE, Béliveau C, Vandenbol M, Francis F, Brasseur R, Cusson M, Haubruge E.

FEBS Lett. 2008 Jun 11;582(13):1928-34. doi: 10.1016/j.febslet.2008.04.043. Epub 2008 May 6. Erratum in: FEBS Lett. 2008 Jul 9;582(16):2471.

41.

Exploring the active site cavity of human pancreatic lipase.

Colin DY, Deprez-Beauclair P, Allouche M, Brasseur R, Kerfelec B.

Biochem Biophys Res Commun. 2008 Jun 6;370(3):394-8. doi: 10.1016/j.bbrc.2008.03.043. Epub 2008 Mar 17.

PMID:
18353248
42.

Structural polymorphism of two CPP: an important parameter of activity.

Deshayes S, Decaffmeyer M, Brasseur R, Thomas A.

Biochim Biophys Acta. 2008 May;1778(5):1197-205. doi: 10.1016/j.bbamem.2008.01.027. Epub 2008 Feb 14.

43.

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling.

Adam B, Charloteaux B, Beaufays J, Vanhamme L, Godfroid E, Brasseur R, Lins L.

BMC Struct Biol. 2008 Jan 11;8:1. doi: 10.1186/1472-6807-8-1.

44.

Characterization of the interactions between fluoroquinolone antibiotics and lipids: a multitechnique approach.

Bensikaddour H, Fa N, Burton I, Deleu M, Lins L, Schanck A, Brasseur R, Dufrêne YF, Goormaghtigh E, Mingeot-Leclercq MP.

Biophys J. 2008 Apr 15;94(8):3035-46. doi: 10.1529/biophysj.107.114843. Epub 2008 Jan 4.

45.

Hydrophobic substitutions in the first residue of the CRAC segment of the gp41 protein of HIV.

Vishwanathan SA, Thomas A, Brasseur R, Epand RF, Hunter E, Epand RM.

Biochemistry. 2008 Jan 8;47(1):124-30. Epub 2007 Dec 15.

PMID:
18081318
46.

Tilted peptides: a structural motif involved in protein membrane insertion?

Lins L, Brasseur R.

J Pept Sci. 2008 Apr;14(4):416-22.

PMID:
18069746
47.

The minimal fusion peptide of simian immunodeficiency virus corresponds to the 11 first residues of gp32.

Lorin A, Lins L, Stroobant V, Brasseur R, Charloteaux B.

J Pept Sci. 2008 Apr;14(4):423-8.

PMID:
17994611
48.

Probing the interaction forces between hydrophobic peptides and supported lipid bilayers using AFM.

Andre G, Brasseur R, Dufrêne YF.

J Mol Recognit. 2007 Nov-Dec;20(6):538-45.

PMID:
17891753
49.

Lipid-destabilizing properties of the hydrophobic helices H8 and H9 from colicin E1.

Lins L, El Kirat K, Charloteaux B, Flore C, Stroobant V, Thomas A, Dufrene Y, Brasseur R.

Mol Membr Biol. 2007 Sep-Dec;24(5-6):419-30.

PMID:
17710646
50.

Mutational analysis of the TRE2 oncogene encoding an inactive RabGAP.

Bizimungu C, Thomas A, Brasseur R, Vandenbol M.

Biotechnol Lett. 2007 Dec;29(12):1927-37. Epub 2007 Aug 15.

PMID:
17701273

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