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Items: 1 to 50 of 158

1.

The role of vitamin D in normal and pathologic processes in the colon.

Kim KE, Brasitus TA.

Curr Opin Gastroenterol. 2001 Jan;17(1):72-7.

PMID:
17031154
2.

Transforming growth factor-beta 1 signaling contributes to Caco-2 cell growth inhibition induced by 1,25(OH)(2)D(3).

Chen A, Davis BH, Sitrin MD, Brasitus TA, Bissonnette M.

Am J Physiol Gastrointest Liver Physiol. 2002 Oct;283(4):G864-74.

3.

Regulation of rat ileal NHE3 by 1,25(OH)2-vitamin D3.

Gill R, Nazir TM, Wali R, Sitrin M, Brasitus TA, Ramaswamy K, Dudeja PK.

Dig Dis Sci. 2002 May;47(5):1169-74.

PMID:
12018917
4.
5.

Differential regulation of the expression of Na(+)/H(+) exchanger isoform NHE3 by PKC-alpha in Caco-2 cells.

Alrefai WA, Scaglione-Sewell B, Tyagi S, Wartman L, Brasitus TA, Ramaswamy K, Dudeja PK.

Am J Physiol Cell Physiol. 2001 Nov;281(5):C1551-8.

6.

PKC-delta inhibits anchorage-dependent and -independent growth, enhances differentiation, and increases apoptosis in CaCo-2 cells.

Cerda SR, Bissonnette M, Scaglione-Sewell B, Lyons MR, Khare S, Mustafi R, Brasitus TA.

Gastroenterology. 2001 Jun;120(7):1700-12.

PMID:
11375951
7.

A vitamin D3 analog induces a G1-phase arrest in CaCo-2 cells by inhibiting cdk2 and cdk6: roles of cyclin E, p21Waf1, and p27Kip1.

Scaglione-Sewell BA, Bissonnette M, Skarosi S, Abraham C, Brasitus TA.

Endocrinology. 2000 Nov;141(11):3931-9.

PMID:
11089522
8.

Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1.

Bissonnette M, Khare S, von Lintig FC, Wali RK, Nguyen L, Zhang Y, Hart J, Skarosi S, Varki N, Boss GR, Brasitus TA.

Cancer Res. 2000 Aug 15;60(16):4602-9.

9.

Inhibition of O(6)-methylguanine-DNA methyltransferase increases azoxymethane-induced colonic tumors in rats.

Wali RK, Skarosi S, Hart J, Zhang Y, Dolan ME, Moschel RC, Nguyen L, Mustafi R, Brasitus TA, Bissonnette M.

Carcinogenesis. 1999 Dec;20(12):2355-60.

PMID:
10590233
10.

1,25-Dihydroxyvitamin D(3) stimulates activator protein-1-dependent Caco-2 cell differentiation.

Chen A, Davis BH, Bissonnette M, Scaglione-Sewell B, Brasitus TA.

J Biol Chem. 1999 Dec 10;274(50):35505-13.

11.

Rapid effects of 1,25(OH)2 vitamin D3 on signal transduction systems in colonic cells.

Sitrin MD, Bissonnette M, Bolt MJ, Wali R, Khare S, Scaglione-Sewell B, Skarosi S, Brasitus TA.

Steroids. 1999 Jan-Feb;64(1-2):137-42. Review.

PMID:
10323682
12.

1,25-dihydroxyvitamin D3 but not TPA activates PLD in Caco-2 cells via pp60(c-src) and RhoA.

Khare S, Bissonnette M, Wali R, Skarosi S, Boss GR, von Lintig FC, Scaglione-Sewell B, Sitrin MD, Brasitus TA.

Am J Physiol. 1999 Apr;276(4 Pt 1):G1005-15.

PMID:
10198345
13.

1,25-dihydroxyvitamin D3 and TPA activate phospholipase D in Caco-2 cells: role of PKC-alpha.

Khare S, Bissonnette M, Scaglione-Sewell B, Wali RK, Sitrin MD, Brasitus TA.

Am J Physiol. 1999 Apr;276(4):G993-G1004. doi: 10.1152/ajpgi.1999.276.4.G993.

PMID:
10198344
14.

Expression of G protein alpha subunits in normal rat colon and in azoxymethane-induced colonic neoplasms.

Bolt MJ, Mailloux RJ, Rasenick MM, Wali RK, Skarosi S, Bissonnette M, Brasitus TA, Sitrin MD.

Gastroenterology. 1998 Dec;115(6):1494-503.

PMID:
9834277
15.

1,25-Dihydroxyvitamin D3 targets PKC-betaII but not PKC-alpha to the basolateral plasma membranes of rat colonocytes.

Wali RK, Bissonnette M, Skarosi S, Khare S, Sitrin M, Brasitus TA.

Biochem Biophys Res Commun. 1998 Sep 8;250(1):48-52.

PMID:
9735329
16.

PKC isoforms: villains in colon cancer?

Brasitus TA, Bissonnette M.

Gastroenterology. 1998 Jul;115(1):225-7. No abstract available.

PMID:
9649481
17.

Enrichment of the more hydrophilic bile acid ursodeoxycholic acid in the fecal water-soluble fraction after feeding to rats with colon polyps.

Batta AK, Salen G, Holubec H, Brasitus TA, Alberts D, Earnest DL.

Cancer Res. 1998 Apr 15;58(8):1684-7.

18.

Decreased PKC-alpha expression increases cellular proliferation, decreases differentiation, and enhances the transformed phenotype of CaCo-2 cells.

Scaglione-Sewell B, Abraham C, Bissonnette M, Skarosi SF, Hart J, Davidson NO, Wali RK, Davis BH, Sitrin M, Brasitus TA.

Cancer Res. 1998 Mar 1;58(5):1074-81.

19.

Protein kinase C alpha modulates growth and differentiation in Caco-2 cells.

Abraham C, Scaglione-Sewell B, Skarosi SF, Qin W, Bissonnette M, Brasitus TA.

Gastroenterology. 1998 Mar;114(3):503-9.

PMID:
9496940
20.

Inverse relationship between membrane lipid fluidity and activity of Na+/H+ exchangers, NHE1 and NHE3, in transfected fibroblasts.

Bookstein C, Musch MW, Dudeja PK, McSwine RL, Xie Y, Brasitus TA, Rao MC, Chang EB.

J Membr Biol. 1997 Dec 1;160(3):183-92.

PMID:
9425602
21.

1,25 dihydroxyvitamin D3 stimulates phospholipase C-gamma in rat colonocytes: role of c-Src in PLC-gamma activation.

Khare S, Bolt MJ, Wali RK, Skarosi SF, Roy HK, Niedziela S, Scaglione-Sewell B, Aquino B, Abraham C, Sitrin MD, Brasitus TA, Bissonnette M.

J Clin Invest. 1997 Apr 15;99(8):1831-41.

22.

Transport of n-butyrate into human colonic luminal membrane vesicles.

Harig JM, Ng EK, Dudeja PK, Brasitus TA, Ramaswamy K.

Am J Physiol. 1996 Sep;271(3 Pt 1):G415-22.

PMID:
8843764
23.

Protein kinase C isoforms in the chemopreventive effects of a novel vitamin D3 analogue in rat colonic tumorigenesis.

Wali RK, Bissonnette M, Khare S, Aquino B, Niedziela S, Sitrin M, Brasitus TA.

Gastroenterology. 1996 Jul;111(1):118-26.

PMID:
8698190
24.

A human antibody binds to alpha-galactose receptors and mimics the effects of Clostridium difficile toxin A in rat colon.

Pothoulakis C, Galili U, Castagliuolo I, Kelly CP, Nikulasson S, Dudeja PK, Brasitus TA, LaMont JT.

Gastroenterology. 1996 Jun;110(6):1704-12.

PMID:
8964394
25.

Shrinkage activates a nonselective conductance: involvement of a Walker-motif protein and PKC.

Nelson DJ, Tien XY, Xie W, Brasitus TA, Kaetzel MA, Dedman JR.

Am J Physiol. 1996 Jan;270(1 Pt 1):C179-91.

PMID:
8772443
26.

Primary chemoprevention strategies for colorectal cancer: ursodeoxycholic acid and other agents.

Brasitus TA.

Gastroenterology. 1995 Dec;109(6):2036-8. No abstract available.

PMID:
7498674
27.

Mechanism of action of chemoprotective ursodeoxycholate in the azoxymethane model of rat colonic carcinogenesis: potential roles of protein kinase C-alpha, -beta II, and -zeta.

Wali RK, Frawley BP Jr, Hartmann S, Roy HK, Khare S, Scaglione-Sewell BA, Earnest DL, Sitrin MD, Brasitus TA, Bissonnette M.

Cancer Res. 1995 Nov 15;55(22):5257-64.

28.
29.

Selective preservation of protein kinase C-zeta in the chemoprevention of azoxymethane-induced colonic tumors by piroxicam.

Roy HK, Bissonnette M, Frawley BP Jr, Wali RK, Niedziela SM, Earnest D, Brasitus TA.

FEBS Lett. 1995 Jun 12;366(2-3):143-5.

30.

Urinary N1-acetylspermidine and N8-acetylspermidine excretion in normal humans and in patients with colorectal cancer.

O'Brien BL, Hankewych M, McCormick D, Jacoby R, Brasitus TA, Halline AG.

Dig Dis Sci. 1995 Jun;40(6):1269-74.

PMID:
7781445
31.
32.

1,25-Dihydroxyvitamin D3 stimulates the phosphorylation of two acidic membrane proteins of 42,000 and 48,000 daltons in rat colonocytes: an effect modulated by vitamin D status.

Wali RK, Bissonnette M, Jiang K, Niedziela SM, Khare S, Roy HK, Sitrin MD, Brasitus TA.

J Cell Physiol. 1995 Feb;162(2):172-80.

PMID:
7822428
33.

Relationship of P-glycoprotein and carcinoembryonic antigen expression in human colon carcinoma to local invasion, DNA ploidy, and disease relapse.

Sinicrope FA, Hart J, Brasitus TA, Michelassi F, Lee JJ, Safa AR.

Cancer. 1994 Dec 1;74(11):2908-17.

PMID:
7954255
34.

Protein kinase C mediates the calcium-induced activation of rat colonic particulate guanylate cyclase.

Khare S, Wilson DM, Tien XY, Wali RK, Bissonnette M, Brasitus TA.

Arch Biochem Biophys. 1994 Oct;314(1):200-4.

PMID:
7944395
35.

Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid.

Earnest DL, Holubec H, Wali RK, Jolley CS, Bissonette M, Bhattacharyya AK, Roy H, Khare S, Brasitus TA.

Cancer Res. 1994 Oct 1;54(19):5071-4.

36.

The effect of bile acids and piroxicam on MHC antigen expression in rat colonocytes during colon cancer development.

Rigas B, Tsioulias GJ, Allan C, Wali RK, Brasitus TA.

Immunology. 1994 Oct;83(2):319-23.

37.

Guanylin activates rat colonic particulate guanylate cyclase.

Khare S, Wilson D, Wali RK, Tien XY, Bissonnette M, Niedziela SM, Bolt MJ, Sitrin MD, Brasitus TA.

Biochem Biophys Res Commun. 1994 Sep 30;203(3):1432-7.

PMID:
7945291
38.

1,25(OH)2 vitamin D3 activates PKC-alpha in Caco-2 cells: a mechanism to limit secosteroid-induced rise in [Ca2+]i.

Bissonnette M, Tien XY, Niedziela SM, Hartmann SC, Frawley BP Jr, Roy HK, Sitrin MD, Perlman RL, Brasitus TA.

Am J Physiol. 1994 Sep;267(3 Pt 1):G465-75.

PMID:
7943245
39.

Mechanisms of Na+ transport in human distal colonic apical membrane vesicles.

Dudeja PK, Baldwin ML, Harig JM, Cragoe EJ Jr, Ramaswamy K, Brasitus TA.

Biochim Biophys Acta. 1994 Jul 13;1193(1):67-76.

PMID:
8038196
40.

The role of protein kinase-C alpha in the activation of particulate guanylate cyclase by 1 alpha,25-dihydroxyvitamin D3 in CaCo-2 cells.

Khare S, Tien XY, Wilson D, Wali RK, Bissonnette BM, Scaglione-Sewell B, Sitrin MD, Brasitus TA.

Endocrinology. 1994 Jul;135(1):277-83.

PMID:
7912183
41.

TPA causes divergent responses of Ca(2+)-dependent and Ca(2+)-independent isoforms of PKC in the nuclei of Caco-2 cells.

Frawley BP Jr, Tien XY, Hartmann SC, Wali RK, Niedziela SM, Davidson NO, Sitrin MD, Brasitus TA, Bissonnette M.

Biochim Biophys Acta. 1994 Jun 30;1222(2):301-5.

PMID:
8031867
42.

Vitamin D status modulates rat colonic M3 muscarinic receptor characteristics and coupling to guanylate cyclase.

Khare S, Tien XY, Wilson D, Wali RK, Bissonnette BM, Sitrin MD, Brasitus TA.

FEBS Lett. 1994 Jun 20;347(1):27-30.

43.

Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of Caco-2 cells.

Halline AG, Davidson NO, Skarosi SF, Sitrin MD, Tietze C, Alpers DH, Brasitus TA.

Endocrinology. 1994 Apr;134(4):1710-7.

PMID:
8137734
44.

Activation of the cystic fibrosis transmembrane conductance regulator by cGMP in the human colonic cancer cell line, Caco-2.

Tien XY, Brasitus TA, Kaetzel MA, Dedman JR, Nelson DJ.

J Biol Chem. 1994 Jan 7;269(1):51-4.

45.

Na+ transport in human proximal colonic apical membrane vesicles.

Dudeja PK, Harig JM, Baldwin ML, Cragoe EJ Jr, Ramaswamy K, Brasitus TA.

Gastroenterology. 1994 Jan;106(1):125-33.

PMID:
8276173
46.

K-ras mutations in putative preneoplastic lesions in human colon.

Pretlow TP, Brasitus TA, Fulton NC, Cheyer C, Kaplan EL.

J Natl Cancer Inst. 1993 Dec 15;85(24):2004-7.

PMID:
8246286
47.

M3 muscarinic receptors on rat colonocytes are coupled to particulate guanylate cyclase activation.

Khare S, Wilson DM, Tien XY, Brasitus TA.

Biochim Biophys Acta. 1993 Nov 7;1179(2):234-7.

PMID:
8105894
48.

Characterization of the 1,25-dihydroxycholecalciferol-stimulated calcium influx pathway in CaCo-2 cells.

Tien XY, Katnik C, Qasawa BM, Sitrin MD, Nelson DJ, Brasitus TA.

J Membr Biol. 1993 Nov;136(2):159-68.

PMID:
8107072
49.

1,25-Dihydroxycholecalciferol rapidly activates rat colonic particulate guanylate cyclase via a protein kinase C-dependent mechanism.

Khare S, Wilson DM, Tien XY, Dudeja PK, Wali RK, Sitrin MD, Brasitus TA.

Endocrinology. 1993 Nov;133(5):2213-9.

PMID:
8104780
50.

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