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Items: 1 to 50 of 81

1.

Melanoma to Vitiligo: The Melanocyte in Biology & Medicine-Joint Montagna Symposium on the Biology of Skin/PanAmerican Society for Pigment Cell Research Annual Meeting.

Leachman SA, Hornyak TJ, Barsh G, Bastian BC, Brash DE, Cleaver JE, Cooper CD, D'Orazio JA, Fujita M, Holmen SL, Indra AK, Kraemer KH, Le Poole IC, Lo RS, Lund AW, Manga P, Pavan WJ, Setaluri V, Stemwedel CE, Kulesz-Martin MF.

J Invest Dermatol. 2019 Jul 23. pii: S0022-202X(19)32550-3. doi: 10.1016/j.jid.2019.03.1164. [Epub ahead of print] No abstract available.

PMID:
31348921
2.

Publisher Correction: A call for a better understanding of causation in cell biology.

Bizzarri M, Brash DE, Briscoe J, Grieneisen VA, Stern CD, Levin M.

Nat Rev Mol Cell Biol. 2019 Jun;20(6):384. doi: 10.1038/s41580-019-0130-6.

PMID:
31000809
3.

A call for a better understanding of causation in cell biology.

Bizzarri M, Brash DE, Briscoe J, Grieneisen VA, Stern CD, Levin M.

Nat Rev Mol Cell Biol. 2019 May;20(5):261-262. doi: 10.1038/s41580-019-0127-1. No abstract available. Erratum in: Nat Rev Mol Cell Biol. 2019 Apr 18;:.

PMID:
30962573
4.

Accelerating cancer without mutations.

Brash DE.

Elife. 2019 Mar 21;8. pii: e45809. doi: 10.7554/eLife.45809.

5.

Chemiexcitation and Its Implications for Disease.

Brash DE, Goncalves LCP, Bechara EJH; Excited-State Medicine Working Group.

Trends Mol Med. 2018 Jun;24(6):527-541. doi: 10.1016/j.molmed.2018.04.004. Epub 2018 May 8. Review.

6.

Fluorouracil Enhances Photodynamic Therapy of Squamous Cell Carcinoma via a p53-Independent Mechanism that Increases Protoporphyrin IX levels and Tumor Cell Death.

Anand S, Rollakanti KR, Brankov N, Brash DE, Hasan T, Maytin EV.

Mol Cancer Ther. 2017 Jun;16(6):1092-1101. doi: 10.1158/1535-7163.MCT-16-0608. Epub 2017 Mar 23.

7.

Unanticipated role of melanin in causing carcinogenic cyclobutane pyrimidine dimmers.

Premi S, Brash DE.

Mol Cell Oncol. 2015 Jun 23;3(1):e1033588. doi: 10.1080/23723556.2015.1033588. eCollection 2016 Jan. Erratum in: Mol Cell Oncol. 2016 Jul;3(4):e1198570.

8.

Chemical excitation of electrons: A dark path to melanoma.

Premi S, Brash DE.

DNA Repair (Amst). 2016 Aug;44:169-177. doi: 10.1016/j.dnarep.2016.05.023. Epub 2016 Jun 1. Review.

9.

UV-induced Melanin Chemiexcitation: A New Mode of Melanoma Pathogenesis.

Brash DE.

Toxicol Pathol. 2016 Jun;44(4):552-4. doi: 10.1177/0192623316632072. Epub 2016 Mar 7.

10.

Cancer. Preprocancer.

Brash DE.

Science. 2015 May 22;348(6237):867-8. doi: 10.1126/science.aac4435. No abstract available.

PMID:
25999495
11.

Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.

Premi S, Wallisch S, Mano CM, Weiner AB, Bacchiocchi A, Wakamatsu K, Bechara EJ, Halaban R, Douki T, Brash DE.

Science. 2015 Feb 20;347(6224):842-7. doi: 10.1126/science.1256022.

12.

UV signature mutations.

Brash DE.

Photochem Photobiol. 2015 Jan-Feb;91(1):15-26. doi: 10.1111/php.12377. Epub 2014 Nov 28. Review.

13.

Enhancing the detection of barcoded reads in high throughput DNA sequencing data by controlling the false discovery rate.

Buschmann T, Zhang R, Brash DE, Bystrykh LV.

BMC Bioinformatics. 2014 Aug 7;15:264. doi: 10.1186/1471-2105-15-264.

14.

Common contaminants in next-generation sequencing that hinder discovery of low-abundance microbes.

Laurence M, Hatzis C, Brash DE.

PLoS One. 2014 May 16;9(5):e97876. doi: 10.1371/journal.pone.0097876. eCollection 2014.

15.

Clonal growth of human melanocytes using cell-free extracellular matrix.

Zhang R, Premi S, Kilic SS, Bacchiocchi A, Halaban R, Brash DE.

Pigment Cell Melanoma Res. 2013 Nov;26(6):925-7. doi: 10.1111/pcmr.12159. Epub 2013 Sep 19. No abstract available.

16.

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

Krauthammer M, Kong Y, Ha BH, Evans P, Bacchiocchi A, McCusker JP, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, Bosenberg M, Sznol M, Kluger HM, Brash DE, Stern DF, Materin MA, Lo RS, Mane S, Ma S, Kidd KK, Hayward NK, Lifton RP, Schlessinger J, Boggon TJ, Halaban R.

Nat Genet. 2012 Sep;44(9):1006-14. doi: 10.1038/ng.2359. Epub 2012 Jul 29.

17.

Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair.

Rochette PJ, Brash DE.

PLoS Genet. 2010 Apr 29;6(4):e1000926. doi: 10.1371/journal.pgen.1000926.

18.

Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia.

Klein AM, Brash DE, Jones PH, Simons BD.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):270-5. doi: 10.1073/pnas.0909738107. Epub 2009 Dec 15.

19.

Influence of cytosine methylation on ultraviolet-induced cyclobutane pyrimidine dimer formation in genomic DNA.

Rochette PJ, Lacoste S, Therrien JP, Bastien N, Brash DE, Drouin R.

Mutat Res. 2009 Jun 1;665(1-2):7-13. doi: 10.1016/j.mrfmmm.2009.02.008. Epub 2009 Feb 28.

PMID:
19427505
20.

Preneoplastic lesion growth driven by the death of adjacent normal stem cells.

Chao DL, Eck JT, Brash DE, Maley CC, Luebeck EG.

Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15034-9. doi: 10.1073/pnas.0802211105. Epub 2008 Sep 24.

21.

Progressive apoptosis resistance prior to senescence and control by the anti-apoptotic protein BCL-xL.

Rochette PJ, Brash DE.

Mech Ageing Dev. 2008 Apr;129(4):207-14. doi: 10.1016/j.mad.2007.12.007. Epub 2008 Jan 4.

22.

Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling.

Knezevic D, Zhang W, Rochette PJ, Brash DE.

Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11286-91. Epub 2007 Jun 22.

23.

Roles of the transcription factor p53 in keratinocyte carcinomas.

Brash DE.

Br J Dermatol. 2006 May;154 Suppl 1:8-10. Review.

PMID:
16712710
24.

Keratinocyte apoptosis in epidermal development and disease.

Raj D, Brash DE, Grossman D.

J Invest Dermatol. 2006 Feb;126(2):243-57. Review.

25.

PTCH codon 1315 polymorphism and risk for nonmelanoma skin cancer.

Asplund A, Gustafsson AC, Wikonkal NM, Sela A, Leffell DJ, Kidd K, Lundeberg J, Brash DE, Pontén F.

Br J Dermatol. 2005 May;152(5):868-73.

PMID:
15888139
26.

Colonization of adjacent stem cell compartments by mutant keratinocytes.

Brash DE, Zhang W, Grossman D, Takeuchi S.

Semin Cancer Biol. 2005 Apr;15(2):97-102. Review.

PMID:
15652454
27.

UVB-induced apoptosis drives clonal expansion during skin tumor development.

Zhang W, Hanks AN, Boucher K, Florell SR, Allen SM, Alexander A, Brash DE, Grossman D.

Carcinogenesis. 2005 Jan;26(1):249-57. Epub 2004 Oct 21.

28.

Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin.

Takeuchi S, Zhang W, Wakamatsu K, Ito S, Hearing VJ, Kraemer KH, Brash DE.

Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15076-81. Epub 2004 Oct 11.

29.

Role of E2F1 in apoptosis: a case study in feedback loops.

Knezevic D, Brash DE.

Cell Cycle. 2004 Jun;3(6):729-32. Epub 2004 Jun 6. Review.

PMID:
15107604
30.

Creating knowledgebases to text-mine PUBMED articles using clustering techniques.

Crasto CJ, Morse TM, Migliore M, Nadkarni P, Hines M, Brash DE, Miller PL, Shepherd GM.

AMIA Annu Symp Proc. 2003:821.

31.

Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones.

Remenyik E, Wikonkál NM, Zhang W, Paliwal V, Brash DE.

Oncogene. 2003 Sep 25;22(41):6369-76.

PMID:
14508517
32.

Photocopying cancer cells.

Brash DE.

J Invest Dermatol. 2003 Jul;121(1):XII-V. Review. No abstract available.

33.

Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.

Wikonkal NM, Remenyik E, Knezevic D, Zhang W, Liu M, Zhao H, Berton TR, Johnson DG, Brash DE.

Nat Cell Biol. 2003 Jul;5(7):655-60.

PMID:
12833065
34.

A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen.

Xue D, Shi H, Smith JD, Chen X, Noe DA, Cedervall T, Yang DD, Eynon E, Brash DE, Kashgarian M, Flavell RA, Wolin SL.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7503-8. Epub 2003 Jun 3.

35.

New careers for antioxidants.

Brash DE, Havre PA.

Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):13969-71. Epub 2002 Oct 21. Review. No abstract available.

36.
37.

The DNA damage signal for Mdm2 regulation, Trp53 induction, and sunburn cell formation in vivo originates from actively transcribed genes.

Brash DE, Wikonkal NM, Remenyik E, van der Horst GT, Friedberg EC, Cheo DL, van Steeg H, Westerman A, van Kranen HJ.

J Invest Dermatol. 2001 Nov;117(5):1234-40.

38.

Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations.

Zhang W, Remenyik E, Zelterman D, Brash DE, Wikonkal NM.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13948-53. Epub 2001 Nov 13.

39.

Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53.

Grossman D, Kim PJ, Blanc-Brude OP, Brash DE, Tognin S, Marchisio PC, Altieri DC.

J Clin Invest. 2001 Oct;108(7):991-9.

40.

Ultraviolet radiation induced signature mutations in photocarcinogenesis.

Wikonkal NM, Brash DE.

J Investig Dermatol Symp Proc. 1999 Sep;4(1):6-10. Review.

41.

Skin precancer.

Brash DE, Pontén J.

Cancer Surv. 1998;32:69-113. Review.

PMID:
10489624
42.
43.

UV induces p21WAF1/CIP1 protein in keratinocytes without p53.

Liu M, Wikonkal NM, Brash DE.

J Invest Dermatol. 1999 Aug;113(2):283-4. No abstract available.

44.

Antioxidant action via p53-mediated apoptosis.

Liu M, Pelling JC, Ju J, Chu E, Brash DE.

Cancer Res. 1998 Apr 15;58(8):1723-9.

45.

Sunlight and the onset of skin cancer.

Brash DE.

Trends Genet. 1997 Oct;13(10):410-4. Review.

PMID:
9351343
46.

Frequent clones of p53-mutated keratinocytes in normal human skin.

Jonason AS, Kunala S, Price GJ, Restifo RJ, Spinelli HM, Persing JA, Leffell DJ, Tarone RE, Brash DE.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14025-9.

47.

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas.

Gailani MR, Ståhle-Bäckdahl M, Leffell DJ, Glynn M, Zaphiropoulos PG, Pressman C, Undén AB, Dean M, Brash DE, Bale AE, Toftgård R.

Nat Genet. 1996 Sep;14(1):78-81.

PMID:
8782823
48.

Sunlight and skin cancer.

Leffell DJ, Brash DE.

Sci Am. 1996 Jul;275(1):52-3, 56-9. No abstract available.

PMID:
8658110
49.

Cellular proofreading.

Brash DE.

Nat Med. 1996 May;2(5):525-6. No abstract available.

PMID:
8616708
50.

Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion.

Brash DE, Ziegler A, Jonason AS, Simon JA, Kunala S, Leffell DJ.

J Investig Dermatol Symp Proc. 1996 Apr;1(2):136-42. Review.

PMID:
9627707

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