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Items: 45

1.

Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds.

Bracha D, Walls MT, Wei MT, Zhu L, Kurian M, Avalos JL, Toettcher JE, Brangwynne CP.

Cell. 2019 Jan 10;176(1-2):407. doi: 10.1016/j.cell.2018.12.026. No abstract available.

PMID:
30633909
2.

Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome.

Shin Y, Chang YC, Lee DSW, Berry J, Sanders DW, Ronceray P, Wingreen NS, Haataja M, Brangwynne CP.

Cell. 2018 Nov 29;175(6):1481-1491.e13. doi: 10.1016/j.cell.2018.10.057.

PMID:
30500535
3.

Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds.

Bracha D, Walls MT, Wei MT, Zhu L, Kurian M, Avalos JL, Toettcher JE, Brangwynne CP.

Cell. 2018 Nov 29;175(6):1467-1480.e13. doi: 10.1016/j.cell.2018.10.048. Erratum in: Cell. 2019 Jan 10;176(1-2):407.

PMID:
30500534
4.

Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli.

Dine E, Gil AA, Uribe G, Brangwynne CP, Toettcher JE.

Cell Syst. 2018 Jun 27;6(6):655-663.e5. doi: 10.1016/j.cels.2018.05.002. Epub 2018 May 30.

PMID:
29859829
5.

Physical principles of intracellular organization via active and passive phase transitions.

Berry J, Brangwynne CP, Haataja M.

Rep Prog Phys. 2018 Apr;81(4):046601. doi: 10.1088/1361-6633/aaa61e. Epub 2018 Jan 9.

PMID:
29313527
6.

Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles.

Wei MT, Elbaum-Garfinkle S, Holehouse AS, Chen CC, Feric M, Arnold CB, Priestley RD, Pappu RV, Brangwynne CP.

Nat Chem. 2017 Nov;9(11):1118-1125. doi: 10.1038/nchem.2803. Epub 2017 Jun 26.

PMID:
29064502
7.

Liquid phase condensation in cell physiology and disease.

Shin Y, Brangwynne CP.

Science. 2017 Sep 22;357(6357). pii: eaaf4382. doi: 10.1126/science.aaf4382. Review.

PMID:
28935776
8.

Neurodegenerative disease: RNA repeats put a freeze on cells.

Sanders DW, Brangwynne CP.

Nature. 2017 Jun 8;546(7657):215-216. doi: 10.1038/nature22503. Epub 2017 May 31. No abstract available.

PMID:
28562583
9.

Farming and public goods production in Caenorhabditis elegans populations.

Thutupalli S, Uppaluri S, Constable GW, Levin SA, Stone HA, Tarnita CE, Brangwynne CP.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2289-2294. doi: 10.1073/pnas.1608961114. Epub 2017 Feb 9.

10.

Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets.

Shin Y, Berry J, Pannucci N, Haataja MP, Toettcher JE, Brangwynne CP.

Cell. 2017 Jan 12;168(1-2):159-171.e14. doi: 10.1016/j.cell.2016.11.054. Epub 2016 Dec 29.

11.

Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics.

Taylor N, Elbaum-Garfinkle S, Vaidya N, Zhang H, Stone HA, Brangwynne CP.

Soft Matter. 2016 Nov 16;12(45):9142-9150.

PMID:
27791212
12.

Hierarchical Size Scaling during Multicellular Growth and Development.

Uppaluri S, Weber SC, Brangwynne CP.

Cell Rep. 2016 Oct 4;17(2):345-352. doi: 10.1016/j.celrep.2016.09.007.

13.

Cell division: A sticky problem for chromosomes.

Brangwynne CP, Marko JF.

Nature. 2016 Jul 14;535(7611):234-5. doi: 10.1038/nature18904. Epub 2016 Jun 29. No abstract available.

PMID:
27362225
14.

Coexisting Liquid Phases Underlie Nucleolar Subcompartments.

Feric M, Vaidya N, Harmon TS, Mitrea DM, Zhu L, Richardson TM, Kriwacki RW, Pappu RV, Brangwynne CP.

Cell. 2016 Jun 16;165(7):1686-1697. doi: 10.1016/j.cell.2016.04.047. Epub 2016 May 19.

15.

Liquids, Fibers, and Gels: The Many Phases of Neurodegeneration.

Elbaum-Garfinkle S, Brangwynne CP.

Dev Cell. 2015 Dec 7;35(5):531-532. doi: 10.1016/j.devcel.2015.11.014.

16.

Soft viscoelastic properties of nuclear actin age oocytes due to gravitational creep.

Feric M, Broedersz CP, Brangwynne CP.

Sci Rep. 2015 Nov 18;5:16607. doi: 10.1038/srep16607.

17.

RNA Controls PolyQ Protein Phase Transitions.

Zhang H, Elbaum-Garfinkle S, Langdon EM, Taylor N, Occhipinti P, Bridges AA, Brangwynne CP, Gladfelter AS.

Mol Cell. 2015 Oct 15;60(2):220-30. doi: 10.1016/j.molcel.2015.09.017.

18.

Remodeling nuclear architecture allows efficient transport of herpesvirus capsids by diffusion.

Bosse JB, Hogue IB, Feric M, Thiberge SY, Sodeik B, Brangwynne CP, Enquist LW.

Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):E5725-33. doi: 10.1073/pnas.1513876112. Epub 2015 Oct 5.

19.

RNA transcription modulates phase transition-driven nuclear body assembly.

Berry J, Weber SC, Vaidya N, Haataja M, Brangwynne CP.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):E5237-45. doi: 10.1073/pnas.1509317112. Epub 2015 Sep 8.

20.

A size threshold governs Caenorhabditis elegans developmental progression.

Uppaluri S, Brangwynne CP.

Proc Biol Sci. 2015 Aug 22;282(1813):20151283. doi: 10.1098/rspb.2015.1283.

21.

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics.

Elbaum-Garfinkle S, Kim Y, Szczepaniak K, Chen CC, Eckmann CR, Myong S, Brangwynne CP.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7189-94. doi: 10.1073/pnas.1504822112. Epub 2015 May 26.

22.

Nuclear bodies: the emerging biophysics of nucleoplasmic phases.

Zhu L, Brangwynne CP.

Curr Opin Cell Biol. 2015 Jun;34:23-30. doi: 10.1016/j.ceb.2015.04.003. Epub 2015 May 15. Review.

23.

Worms under Pressure: Bulk Mechanical Properties of C. elegans Are Independent of the Cuticle.

Gilpin W, Uppaluri S, Brangwynne CP.

Biophys J. 2015 Apr 21;108(8):1887-98. doi: 10.1016/j.bpj.2015.03.020.

24.

Inverse size scaling of the nucleolus by a concentration-dependent phase transition.

Weber SC, Brangwynne CP.

Curr Biol. 2015 Mar 2;25(5):641-6. doi: 10.1016/j.cub.2015.01.012. Epub 2015 Feb 19.

25.

Phase transitions and size scaling of membrane-less organelles.

Brangwynne CP.

J Cell Biol. 2013 Dec 23;203(6):875-81. doi: 10.1083/jcb.201308087. Review.

26.

Spatial organization of the cell cytoplasm by position-dependent phase separation.

Lee CF, Brangwynne CP, Gharakhani J, Hyman AA, Jülicher F.

Phys Rev Lett. 2013 Aug 23;111(8):088101. Epub 2013 Aug 20. Erratum in: Phys Rev Lett. 2013 Dec 27;111(26):269902.

PMID:
24010479
27.

A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells.

Feric M, Brangwynne CP.

Nat Cell Biol. 2013 Oct;15(10):1253-9. doi: 10.1038/ncb2830. Epub 2013 Sep 1.

28.

Nuclear mechanics: lamin webs and pathological blebs.

Broedersz CP, Brangwynne CP.

Nucleus. 2013 May-Jun;4(3):156-9. doi: 10.4161/nucl.25019. Epub 2013 May 15.

29.

The micro and macro of RNA function.

Brangwynne CP, Johnson TL.

Mol Biol Cell. 2013 Mar;24(6):679. doi: 10.1091/mbc.E13-01-0012. No abstract available.

30.

Getting RNA and protein in phase.

Weber SC, Brangwynne CP.

Cell. 2012 Jun 8;149(6):1188-91. doi: 10.1016/j.cell.2012.05.022. Review.

31.

Beyond stereospecificity: liquids and mesoscale organization of cytoplasm.

Hyman AA, Brangwynne CP.

Dev Cell. 2011 Jul 19;21(1):14-6. doi: 10.1016/j.devcel.2011.06.013.

32.

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes.

Brangwynne CP, Mitchison TJ, Hyman AA.

Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4334-9. doi: 10.1073/pnas.1017150108. Epub 2011 Feb 28.

33.

Centrosome size sets mitotic spindle length in Caenorhabditis elegans embryos.

Greenan G, Brangwynne CP, Jaensch S, Gharakhani J, Jülicher F, Hyman AA.

Curr Biol. 2010 Feb 23;20(4):353-8. doi: 10.1016/j.cub.2009.12.050. Epub 2010 Feb 4.

34.

Intracellular transport by active diffusion.

Brangwynne CP, Koenderink GH, MacKintosh FC, Weitz DA.

Trends Cell Biol. 2009 Sep;19(9):423-7. doi: 10.1016/j.tcb.2009.04.004. Epub 2009 Aug 21.

PMID:
19699642
35.

Germline P granules are liquid droplets that localize by controlled dissolution/condensation.

Brangwynne CP, Eckmann CR, Courson DS, Rybarska A, Hoege C, Gharakhani J, Jülicher F, Hyman AA.

Science. 2009 Jun 26;324(5935):1729-32. doi: 10.1126/science.1172046. Epub 2009 May 21.

36.

Chapter 19: Mechanical response of cytoskeletal networks.

Gardel ML, Kasza KE, Brangwynne CP, Liu J, Weitz DA.

Methods Cell Biol. 2008;89:487-519. doi: 10.1016/S0091-679X(08)00619-5.

37.

Cytoplasmic diffusion: molecular motors mix it up.

Brangwynne CP, Koenderink GH, MacKintosh FC, Weitz DA.

J Cell Biol. 2008 Nov 17;183(4):583-7. doi: 10.1083/jcb.200806149. Epub 2008 Nov 10. Review.

38.

Nonequilibrium microtubule fluctuations in a model cytoskeleton.

Brangwynne CP, Koenderink GH, Mackintosh FC, Weitz DA.

Phys Rev Lett. 2008 Mar 21;100(11):118104. Epub 2008 Mar 21.

PMID:
18517833
39.

Force fluctuations and polymerization dynamics of intracellular microtubules.

Brangwynne CP, MacKintosh FC, Weitz DA.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16128-33. Epub 2007 Oct 2.

40.

Bending dynamics of fluctuating biopolymers probed by automated high-resolution filament tracking.

Brangwynne CP, Koenderink GH, Barry E, Dogic Z, MacKintosh FC, Weitz DA.

Biophys J. 2007 Jul 1;93(1):346-59. Epub 2007 Apr 6.

41.

A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblast-mediated stiffening of collagen gels.

Leung LY, Tian D, Brangwynne CP, Weitz DA, Tschumperlin DJ.

FASEB J. 2007 Jul;21(9):2064-73. Epub 2007 Mar 6.

PMID:
17341683
42.

The cell as a material.

Kasza KE, Rowat AC, Liu J, Angelini TE, Brangwynne CP, Koenderink GH, Weitz DA.

Curr Opin Cell Biol. 2007 Feb;19(1):101-7. Epub 2006 Dec 15. Review.

PMID:
17174543
43.

Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement.

Brangwynne CP, MacKintosh FC, Kumar S, Geisse NA, Talbot J, Mahadevan L, Parker KK, Ingber DE, Weitz DA.

J Cell Biol. 2006 Jun 5;173(5):733-41.

44.

Symmetry-breaking in mammalian cell cohort migration during tissue pattern formation: role of random-walk persistence.

Huang S, Brangwynne CP, Parker KK, Ingber DE.

Cell Motil Cytoskeleton. 2005 Aug;61(4):201-13.

PMID:
15986404
45.

Glioma expansion in collagen I matrices: analyzing collagen concentration-dependent growth and motility patterns.

Kaufman LJ, Brangwynne CP, Kasza KE, Filippidi E, Gordon VD, Deisboeck TS, Weitz DA.

Biophys J. 2005 Jul;89(1):635-50. Epub 2005 Apr 22.

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